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흰쥐에 있어서 납과 카드뮴이 Hepatic Microsomal Electron Transport System 활성도에 미치는 영향
김주봉,장성근,김기웅,송용범,김무호 순천향대학교 1994 논문집 Vol.17 No.3
In rats treated with lead nitrate and cadmium chloride we observed a change of he level of hepatic microsomal protein, cytochrome P-450 and ??, and electron transport system for P-450 dependent reaction. The contents of microsomal protein, P-450 and b5, and activity of NADPH-cytochrome C(P-450) reductase were decreased according to the dosage of lead nitrate and cadmium chloride. On the other hand, the activity of NADH-cytochrome ?? reductase was increased according to the dosage of lead nitrate and cadmium chloride. These results suggest that the content and activity of cytochrome dependent mono-oxygenase may be dependent on specificity of substrates, and electron transport occurred through two pathway, that is, NADPH-cytochrome C(P-450) reductase and ?? reductase but NADH-cytochrome ?? reductase was mainly act as a mobile carrier so-called second electron carrier.
김웅흠,김우택,이창연,김동욱,박성기,장무환 동국대학교 경주대학 1993 東國論集 Vol.12 No.-
Hemolytic uremic syndrome is characterized by Coombs-negative microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure in infant and children. At present, E. coli 0157 : H7 and other verotoxin-producing E. coli(VTEC) seem to be a major cause of this illness. The majority of patients have a prodrome of bloody diarrhea, and acute renal failure develops several days to weeks later. Although an optimal treatment remains unknown, the general management of hypertention and renal failure with early and frequent dialysis is the mainatay of treatment, and intravenous administration of immunoglobulin G is like to be effective. We experienced a case composed of bloody diarrhea, seizures, coma, and anuria in 1 year old girl who was diagnosed as HUS and recovered renal function completely with slight impairment of cognitive ability and behavioral function. We presented this case with a review of literatures.
鄭武雄,金善弼 단국대학교 1993 論文集 Vol.27 No.-
This study, as one subject of E·B·S(Environmental Behavior Study) to find out relationship between environment and behavior, is a scientific implementation to control or prevent crime through environmental design. This study takes the hypotesis that environment give cues of crime, when latent criminals percept it, raise crime. Also, by the hypotesis, this study takes the theory that can prevent crime with seeking environmental elements to promote crime, changing or improving it. The purpose of this study is to seek design guideline applicable to our houses and site plan by consideration of the theory and the case study of crime prevention through environmental design.
韓國住居文化의 連續性과 變化性에 관한 硏究 : 改良韓屋의 生活樣式과 空間適應性을 中心으로
鄭武雄,金善弼,李容賑 단국대학교 1992 論文集 Vol.26 No.-
This is a study on the cultural change and continuity of Korean residential settlement. The relationship between residential environment and life style is essential issue of this study. 1. There is a recyclic relationship influencing each other between residential environment and life style. 2. The adaptation process between host oulture and migrant culture is conflict → sublimation → assimilation and the relative strength between wants and needs is a very essential element in cultural settlement. 3. The continuity factors in the reformed house are family room of Anbang, floor panel heating system(Ondol), inner court of life space, veranda floor, place hierarchy in daily life and preference of main floor(Maru) and texture. 4. The changing factors in the reformed house are influenced by daily life needs and reconstruction, extension, equipment improvement, material exchange and some addition facilities. 5. Soccio-cultural control system is necessary to control the speed, frequency and scale of changing tendency.
Paraquat 중독환자의 초기검사로서 sodium dithionite를 이용한 소변내 paraquat검출의 임상적 의의
윤갑준,임경수,이진웅,김영식,이부수,박덕우,김선만,이강현,황성오,안무업 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1
Background : Mortality from paraquat intoxication depends upon plasma paraquat concentration. To know the severity of paraquat intoxication is important for directing therapeutic modality and predicting prognosis. Sodium dithionite test for urinary paraquat provides an easy and simple method to determine the severity of paraquat intoxication in emergency department. purpose : To determine whether the result urinary paraquat test by sodium dithionite can predict outcome in patients with paraquat intoxication in emergency department. Subjects : 48 patients(male 31, female 17, mean age 37 years) who had exposure to paraquat and presented within 24 hours after exposure. Result : Thirty five patients were positive in paraquat urine test and thirteen patients were negative. Clinical manifestations were more severe in positive patients than in negatives. Complication was much more in positives than in negatives. 28 of 35 patients(80%) in positives and 2 of 13 patients(15%) in negatives died. Conclusion : Positive test for urinary paraquat is associated with high mortality and morbidity from paraquat intoxication, and qualitative test for urinary paraquat by sodium dithionite is an useful method to determine the severity of paraquat intoxication in emergency department.
Usefullness of J-turn,pull-release method for intubation of bile duct without accessory in DPOC
( Moo Woong Kim ),( Seo Joon Eun ),( Ui Sin Lee ),( Susie Rah ),( Geum Soo Lee ),( Hyeung Chul Moon ),( Sang Wook Park ),( Gun Young Hong ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Background and Study Aims: The Direct peroral cholangioscopy (POC) using an ultraslim endoscope provides endoscopic visualization of the biliary trees with following major advantages, high quality endoscopic images, a working channel and economical benefit. Despite of these advantages, an accessory usually is required to insert into the bile duct because of acute angle between the duodenum and bile duct and loop formation in stomach. But it has been reported that the intubation without an accessory was possible, so we carried out the study for how to be successful intubation without any accessories under the direct POC. Patients and Methods: From April 2014 to June 2015, we carried out the direct POC using ultraslim endoscope without any accessories in patients who had large or hard stone. Ultraslim endoscopy (Olympus GIF-XP260N) was used for choledochoscopy. Before POC, the orifice of major papilla should be widened enough by EST or EPBD. First, entering the 2nd portion of duodenum, the scope was shortened by right turn, pulling method. Second, it was deflected up (J-turn) carefully and positioned in front of the major papilla. Then pull it slowly toward the major papilla. When the tip of scope reached at papilla orifice, release the J-turn by down regulation of endoscopy with advancing the scope into the bile duct simultaneously. After entering the common bile duct, we performed stone fragmentation with EHL. If the scope could not reach the stone, balloon catheter was used for advancing the scope. Finally the stones were extracted by ERCP. Results: DPOC using an ultraslim endoscope without an accessory was successfully performed in 21 of the 29 (24 for impacted CBD stone, 4 mirrizi syndrome, 1 IHD stone) patients. No significant procedure- related complications such as bleeding, pancreatitis, perforation except one air embolism was noted. Conclusions: Despite of limitation for advancing endoscopy to upper CBD and IHBD, POC using J-turn, pull-release method is considered for successful maneuver for intubation of bile duct. We reported 21 successful cases by this method, further cases are needed to evaluate the effectiveness and safety of this method.