운동자세에 따른 인체부위별 피부온 분포에 관한 연구

정명희,서미아 漢陽大學校 韓國生活科學硏究所 2002 韓國 生活 科學 硏究 Vol.- No.20

This study focuses on the influence of the exercise posture on physiological responses of the human body from the viewpoint of clothing physiology. The distribution of the skin temperature on the body regions for two different exercise and recovery time were examined. Ten untrained female subjects, wearing brassiere and shorts performed 15 minutes of exercise at 50% of maximal oxygen intake, which of each subject for each kind of exercises was decided by use of a bicycle ergometer. Exercise conditions consisted of leg exercise in the supine and the sitting postures. Environmental conditions were at 30±1℃ air temperature, 50±10% relative humidity and 0.2m/sec air velocity. Maximal of oxygen intake of the exercise posture(VO2Pmax), skin temperature(Tsk) on the 13sites of the human body surface, mean skin temperature(Tsk) were measured. As a result, VO2Pmax in the sitting exercise posture was 20% higher than that for the supine exercise posture. Skin temperature on the body regions was significantly different between the supine exercise posture and the sitting exercise posture. In the supine posture, skin temperature from the trunk, chest, abdomen, back and loin were higher than in the sitting posture, while those from the extremities in the sitting posture were significantly larger than those in the supine posture. Skin temperature on the forehead and cheek showed the maximal values. Mean skin temperature was affected by the exercise posture, higher in the supine posture than in the sitting posture.

운동자세 및 의복압이 최대의 산소섭취량(VO₂Pmax)에 미치는 영향

정명희,田村熙子,서미아 漢陽大學校 韓國生活科學硏究所 2001 韓國 生活 科學 硏究 Vol.- No.19

This study focuses on the influence of body pressure for posture and clothing pressure on physiological responses of the human body from the viewpoint of clothing physiology. Physiological responses for different exercise postures and different levels of clothing pressure were examined. Six untrained female subjects performed leg exercises, using a bicycle ergometer in the supine and sitting postures. Clothing used in the experiment consisted of two kinds of sportswear -non-pressure suits and pressure suits-both of which were made in the same shape of short sleeves and short pants and were made of the same material of 90% nylon/10% polyurethane. Environmental conditions were at 30±1℃ air temperature, 50±10% relative humidity and 0.2m/sec air velocity. Clothing pressure on the 10 sites of the human body surface and maximal of oxygen intake(V˙O2Pmax) were measured. As a result, body pressure for posture was significantly higher(45 ~55gf/cm3) than the clothing pressure(3~ 25gf/cm2). V˙O2Pmax during exercise was affected both by the posture and clothing pressure. V˙O2Pmax in the sitting posture was 9∼20% higher than that for the supine posture, and V˙O2Pmax in the pressure suits was 2∼12% higher than that in the non-pressure suits.

카드뮴이 인간 단핵구 세포주(THP-1)에서 cytokine 유전자 발현에 미치는 영향

신동훈,박관규,강미정,서석권,정인성,양선희 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.2

Cadmium, a potent toxic metal, posses a serious environmental threat but the mechanism of its toxicity remains unclear. Also, cadmium is a known immunotoxic agent in animal studies and induces pathophysiological effects by modulating components of immune system. Cytokines are being increasingly recognized as essential mediators of normal and pathologic immune response. Cells of mononuclear phagocytic system are strategically located at portals of entry in humans and therefore may be particularly at risk for cadmium exposure through contaminated air, food, and drinking water. In the present study, we investigated the effect of cadmium cytotoxicity for the monocyte and expression of cytokine gene in the control and cadmium treated human monocytic cell lines using RT-PCR method. The results showed that cadmium inhibited cell proliferation at 0.1mM cadimium treated cells for 24 hours. The TNF-α mRNA was expressed in both control and cadmium treated cells but not IL-6 and IL-1β. The mRNA levels of TNF-αwere examined during 24 hours culture period, at different time points. The expression of TNF-αmRNA increased in both 0.01mM and 0.1mM cadmium treated cells, but did not show dose-response relationship. According to cadimium treated duration, expression of TNF-αmRNA was more decreased in 24 hours than 6 hours. The decreased levels of mRNA of TNF-α suggest that cadmium suppresses its production at the transcription level.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

A cDNA Clone from Broccoli(Brassica oleracea) for a New Type of Oleosin

Suh, Mi Chung,Kim, Young Soon,Hong, Choo Bong,Nam, Sang Hyeon,Cho, Young Hwan 한국식물학회 1999 Journal of Plant Biology Vol.42 No.1

From a differential screening of a cDNA library for broccoli anther, a cDNA clone for oleosin was isolated and named BASC1. BASC1 did not contain the ammo-terminus but probably coded for most of the protein. The open reading frame extending for 212 amino acids had a very long hydrophobic region flanked by amphiphatic regions, the typical pattern for oleosins. In the long hydrophobic region, BASC1 showed strong homologies to the previously reported oleosins. To the carboxy-terminus from the center of ORF, BASC1 is unique in having a region of hydrophilicity in the middle of the amphiphatic stretch. Transcripts of BASC1 were detected from the anther of uninucleate and binucleate pollens, and from the tapetum and pollen.

Plant lipid biology and biotechnology

Suh, Mi Chung,Hahne, Gü,nther,Liu, Jang R.,Stewart Jr., C. Neal Springer-Verlag 2015 Plant cell reports Vol.34 No.4

DEWAX-mediated transcriptional repression of cuticular wax biosynthesis in Arabidopsis thaliana.

Suh, Mi Chung,Go, Young Sam Landes Bioscience 2014 Plant signaling & behavior Vol.9 No.8

<P>The aerial parts of plants are covered with a cuticular wax layer, which is the first barrier between a plant and its environment. Although cuticular wax deposition increases more in the light than in the dark, little is known about the molecular mechanisms underlying the regulation of cuticular wax biosynthesis. Recently DEWAX (Decrease Wax Biosynthesis) encoding an AP2/ERF transcription factor was found to be preferentially expressed in the epidermis and induced by darkness. Wax analysis of the dewax knockout mutant, wild type, and DEWAX overexpression lines (OX) indicates that DEWAX is a negative regulator of cuticular wax biosynthesis. DEWAX represses the expression of wax biosynthetic genes CER1, LACS2, ACLA2, and ECR via direct interaction with their promoters. Cuticular wax biosynthesis is negatively regulated twice a day by the expression of DEWAX; throughout the night and another for stomata closing. Taken together, it is evident that DEWAX-mediated negative regulation of the wax biosynthetic genes plays role in determining the total wax loads produced in Arabidopsis during daily dark and light cycles. In addition, significantly higher levels of DEWAX transcripts in leaves than stems suggest that DEWAX-mediated transcriptional repression might be involved in the organ-specific regulation of total wax amounts on plant surfaces.</P>

Cadimium Resistance in Transgenic Tobacco Plants Expressing the Nicotiana glutinosa L. Methallothionein-like Gene

Suh, Mi Chung,Choi, Doil,Liu, Jang Ryol Korean Society of Molecular Biology 1998 Molecules and cells Vol.8 No.6

Cuticular lipid composition, surface structure, and gene expression in Arabidopsis stem epidermis.

Suh, Mi Chung,Samuels, A Lacey,Jetter, Reinhard,Kunst, Ljerka,Pollard, Mike,Ohlrogge, John,Beisson, Fred American Society of Plant Physiologists 2005 Plant Physiology Vol.139 No.4

<P>All vascular plants are protected from the environment by a cuticle, a lipophilic layer synthesized by epidermal cells and composed of a cutin polymer matrix and waxes. The mechanism by which epidermal cells accumulate and assemble cuticle components in rapidly expanding organs is largely unknown. We have begun to address this question by analyzing the lipid compositional variance, the surface micromorphology, and the transcriptome of epidermal cells in elongating Arabidopsis (Arabidopsis thaliana) stems. The rate of cell elongation is maximal near the apical meristem and decreases steeply toward the middle of the stem, where it is 10 times slower. During and after this elongation, the cuticular wax load and composition remain remarkably constant (32 microg/cm2), indicating that the biosynthetic flux into waxes is closely matched to surface area expansion. By contrast, the load of polyester monomers per unit surface area decreases more than 2-fold from the upper (8 microg/cm2) to the lower (3 microg/cm2) portion of the stem, although the compositional variance is minor. To aid identification of proteins involved in the biosynthesis of waxes and cutin, we have isolated epidermal peels from Arabidopsis stems and determined transcript profiles in both rapidly expanding and nonexpanding cells. This transcriptome analysis was validated by the correct classification of known epidermis-specific genes. The 15% transcripts preferentially expressed in the epidermis were enriched in genes encoding proteins predicted to be membrane associated and involved in lipid metabolism. An analysis of the lipid-related subset is presented.</P>

Session J : Plant Gene Structure and Expression : PROGENY ANALYSIS OF INSECT RESISTANT TOBACOO PLANTS WITH BACILLUS THURINGIENSIS δ - ENDOTOXIN

Mi Chung Suh,Choo Bong Hong,Sang Seock Kim,Woong Seop Sim 생화학분자생물학회(구 한국생화학분자생물학회) 1993 추계학술대회집 Vol.- No.-