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중국 일 종합병원에서 적적 간호인력 추정을 위한 환자분류체계의 타당성 검증
이동매,송영선 대한간호학회 간호행정학회 2005 간호행정학회지 Vol.11 No.2
This study was to setup the basis on hospital and national nursing manpower estimation accurately according to apply patient classification system of Song's study to China hospital system. Method: This study was surveyed to 964 patients at surgical and medical ward on Yanbian University Hospital in China from 17th to 31th January, 2005. Results: There was study results to test hypotheses for estimating optimal nursing manpower as follows. First, a trimodel classification scheme was developed which suggested three categories of patients as minimal care(category 1), moderate care(category 2), intensive care(category 3). Second, there was not significant difference with nursing time by sex. Third, there was not significant difference with nursing time by medical wards. Fourth, there was not significant difference with average nursing care time for each category of patients. Category 1 was estimated to spend average 19.59minutes for patients, Category 2 was about 35.68 minutes, Category 3 was 72.07minutes respectively. Total nursing hours was 62,610 minutes. Conclusion: Patient classification system of Song's study is validity for optimal nursing manpower of hospital in China.
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중국 일 종합병원에서 적정 간호인력 추정을 위한 환자분류체계의 타당성 검증
이동매(Dong Mei Lee),송영선(Sun Song Young) 한국간호행정학회 2005 간호행정학회지 Vol.11 No.2
This study was to setup the basis on hospital and national nursing manpower estimation accurately according to apply patient classification system of Song`s study to China hospital system. Method: This study was surveyed to 964 patients at surgical and medical ward on Yanbian University Hospital in China from 17th to 31th January, 2005, Results: There was study results to test hypotheses for estimating optimal nursing manpower as follows, First, a trimodel classification scheme was developed which suggested three categories of patients as minimal care (category 1), moderate care (category 2), intensive care (category 3), Second, there was not significant difference with nursing time by sex, Third, there was not significant difference with nursing time by medical wards. Fourth, there was not significant difference with average nursing care time for each category of patients. Category 1 was estimated to spend average 19.59minutes for patients, Category 2 was about 35.68 minutes, Category 3 was 72.07minutes respectively, Total nursing hours was 62,610minutes, Conclusion: Patient classification system of Song`s study is validity for nursing manpower of hospital in China.
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Anhai Chen,Chufeng He,Yong Feng,Jie Ling,Xin Peng,Xianlin Liu,Shuang Mao,Yongjia Chen,Mengyao Qin,Shuai Zhang,Yijiang Bai,Jian Song,Zhili Feng,Lu Ma,Dinghua He,Lingyun Mei1 대한이비인후과학회 2023 Clinical and Experimental Otorhinolaryngology Vol.16 No.4
Objectives. Branchio-oto syndrome (BOS) primarily manifests as hearing loss, preauricular pits, and branchial defects. EYA1is the most common pathogenic gene, and splicing mutations account for a substantial proportion of cases. However,few studies have addressed the structural changes in the protein caused by splicing mutations and potential pathogenicfactors, and several studies have shown that middle-ear surgery has limited effectiveness in improving hearing in thesepatients. BOS has also been relatively infrequently reported in the Chinese population. This study explored the ge-netic etiology in the family of a proband with BOS and provided clinical treatment to improve the patient’s hearing. Methods. We collected detailed clinical features and peripheral blood samples from the patients and unaffected individualswithin the family. Pathogenic mutations were identified by whole-exome sequencing and cosegregation analysis andclassified according to the American College of Medical Genetics and Genomics guidelines. Alternative splicing wasverified through a minigene assay. The predicted three-dimensional protein structure and biochemical experimentswere used to investigate the pathogenicity of the mutation. The proband underwent middle-ear surgery and was fol-lowed up at 1 month and 6 months postoperatively to monitor auditory improvement. Results. A novel heterozygous EYA1 splicing variant (c.1050+4 A >C) was identified and classified as pathogenic (PVS1(RNA),PM2, PP1). Skipping of exon 11 of the EYA1 pre-mRNA was confirmed using a minigene assay. This mutation mayimpair EYA1-SIX1 interactions, as shown by an immunoprecipitation assay. The EYA1-Mut protein exhibited cellularmislocalization and decreased protein expression in cytological experiments. Middle-ear surgery significantly improvedhearing loss caused by bone-conduction abnormalities in the proband. Conclusion. We reported a novel splicing variant of EYA1 in a Chinese family with BOS and revealed the potential molec-ular pathogenic mechanism. The significant hearing improvement observed in the proband after middle-ear surgeryprovides a reference for auditory rehabilitation in similar patients.
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Mei Ling Song 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10
Purpose: Life and Death education is an education that helps people to understand life and death correctly, values the present life, and allows them to live more meaningfully. The purpose of this study is to investigate the effect of life and death education on meaning of life, perception of death, attitude on terminating life support, and personality of nursing school students. Methods: The subjects of this study were college of nursing students, who was taking life and death classes at first year of college. The contents of classes were prepared referenced by the thanatology, and well-dying education. The education was consisted of 13 weeks and the contents were consisted with history of death education, the different definitions of death, the death problems of elderly, hospice care, life-sustaining treatment decision related act, death-related legal issue, the funeral culture, and bereavement management of family, meaning of life, and happiness and so on. For investigating the effect of the education, we investigated the meaning of life, attitude of death, perception of death, perception of hospice, attitude on terminating life support, concept of good death, and personality. The data were collected at two times that were at the beginning of the education, and after the education. For analyzing the results, we did pared-test analysis, using SPSS 18.0 program. Results: Total 142 students answered the questionnaires. After taking the life and death education, the meaning of life, perception of death, perception of hospice, attitude on terminating life support, concept of good death, and personality have been significantly changed. Conclusion: According to the results, life and death education can help the nursing students to build positive perception of death, meaning of life, and personality, thus life and death class is a necessary and important class for nursing school students.
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SONG, IK-CHAN,LIANG, ZHE-LONG,LEE, JUNG-CHAN,HUANG, SONG-MEI,KIM, HA-YON,OH, YOON-SUK,YUN, HWAN-JUNG,SUL, JI-YOUNG,JO, DEOG-YEON,KIM, SAMYONG,KIM, JIN-MAN,LEE, HYO-JIN Spandidos Publications 2011 Oncology letters Vol.2 No.6
<P>Lymph node metastasis is considered to be a significant prognostic factor for early gastric cancer (EGC). However, no real consensus exists on which patient and/or tumor characteristics are associated with lymph node metastasis. We investigated whether stromal cell-derived factor (SDF)-1α expression correlates with lymph node metastasis in patients with EGC by immunohistochemically examining the expression of SDF-1α in 138 archival tissue specimens of EGC. Of these specimens, 59 (42.8%) and 79 (57.2%) were grouped into SDF-1α-positive and SDF-1α-negative groups, respectively. No significant differences existed with respect to age, gender, tumor location, proportion of tumors >20 mm in size, macroscopic type, depth of invasion or histology between the SDF-1α-positive and -negative groups. However, the SDF-1α-positive group was significantly correlated with lymphovascular invasion and lymph node metastasis. Results of the univariate analyses indicated that lymphovascular invasion, undifferentiated histology and SDF-1α positivity were statistically significant risk factors affecting lymph node metastasis in patients with EGC. Multivariate analyses showed that lymphovascular invasion [hazard ratio (HR), 8.595; 95% confidence interval (CI), 1.694-43.595; P=0.009], undifferentiated histology (HR, 2.965; 95% CI, 1.037-8.471; P=0.043) and SDF-1α positivity (HR, 2.108; 95% CI, 1.316-10.135; P=0.013) were independent risk factors predicting lymph node metastasis in EGC. In conclusion, these results suggest that SDF-1α expression in tumor cells is a predictive marker of lymph node metastasis in EGC.</P>
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L1 cell adhesion molecule as a novel independent poor prognostic factor in gallbladder carcinoma
Choi, Song-Yi,Jo, Young Suk,Huang, Song-Mei,Liang, Zhe Long,Min, Jeong-Ki,Hong, Hyo Jeong,Kim, Jin-Man Elsevier 2011 Human pathology Vol.42 No.10
<P><B>Summary</B></P><P>Gallbladder carcinoma is a lethal malignancy and is hard to cure by current treatment. Thus, identification of molecular prognostic markers to predict gallbladder carcinoma as therapeutic targets is urgently needed. Recent studies have demonstrated that L1 cell adhesion molecule is associated with the prognosis of variable malignancy. Here, we investigated L1 cell adhesion molecule expression in gallbladder carcinoma and its prognostic significance. In this study, we examined L1 cell adhesion molecule expression in tumor specimens from 69 patients with gallbladder carcinoma by immunohistochemistry and analyzed the correlation between L1 cell adhesion molecule expression and clinicopathologic factors or survival. L1 cell adhesion molecule was not expressed in the normal epithelium of the gallbladder but in 63.8% of gallbladder carcinomas, remarkably at the invasive front of the tumors. In addition, L1 cell adhesion molecule expression was significantly associated with high histologic grade, advanced pathologic T stage and clinical stage, and positive venous/lymphatic invasion. Multivariate analyses showed that L1 cell adhesion molecule expression (hazard ratio, 3.503; <I>P</I> = .028) and clinical stage (hazard ratio, 3.091; <I>P</I> = .042) were independent risk factor for disease-free survival. L1 cell adhesion molecule expression in gallbladder carcinoma was significantly correlated with tumor progression and unfavorable clinicopathologic features. L1 cell adhesion molecule expression was an independent poor prognostic factor for disease-free survival in patients with gallbladder carcinoma. Taken together, our findings suggest that L1 cell adhesion molecule expression could be used as a novel prognostic factor for patient survival and might be a potential therapeutic target in gallbladder carcinomas.</P>
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Frequency Hopping CR MAC Protocol in Cognitive Radio Ad Hoc Network
Mei Bie,Zhe Wang,Wei Xiao,Kai Song 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.9
To insure the fairness for the Cognitive Radio (CR) nodes with various available channels, a frequency hopping CR MAC protocol based dynamic (named DCR-MAC) is proposed. In the case of uneven distribution of frequency spectrum in cognitive Ad Hoc network, based on the numbers of workable channels of each cognitive node, DCR-MAC protocol adjusts access time dynamically, ensuring the node priority access channel number, in order to improve the overall performance of the network. Meanwhile, against the problem of the multi-channel hidden terminal which appears in cognitive network of single wireless interface configuration, through introducing the "data segment" mechanism, and informing present channels occupied condition of adjacent node via receiving node, DCR-MAC protocol broadcast of channel occupation in transmission channel, and prohibit possible data transmission of adjacent node, in order to solve this problem on this account. Finally, proving that DCR-MAC protocol is obviously excelled other FH CR MAC protocols in through put capacity, packet access delay, accessing fairness which through network simulation.
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