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FCP 14 : Screening of psoriatic arthritis in Korean psoriasis patients using PASE questionnaire
( Hyang Suk You ),( Hyun Ho Cho ),( Won Jeong Kim ),( Je Ho Mun ),( Marg Aret Song ),( Hoon Soo Kim ),( Hyun Chang Ko ),( Moon Bum Kim ),( Seung Geun Lee ),( In Sook Lee ),( Byung Soo Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Psoriatic arthritis (PsA) is a chronic seronegative oligoarthritis causing irreversible joint damage. Early recognition of PsA in patients with psoriasis is important to prevent physical disability and deformity. However, diagnosing PsA pose a distinct challenge for most dermatologists in the context of a busy clinic. Objectives: The aim of this study was to validate Psoriatic Arthritis Screening Evaluation (PACE) questionnaire in detecting PsA in Korean patients with psoriasis. Methods: A total 148 patients with a diagnosis of psoriasis, but not previously diagnosed with PsA were administered with PACE questionnaire prospectively. All patients underwent radiologic and laboratory examinations. In addition, they were clinically evaluated by a rheumatologist. Results: Eighteen patients (12.1%) were diagnosed with PsA meeting the Classification Criteria for Psoriatic Arthritis (CASPAR) criteria. The sum of PACE score in patients with PsA showed signifcant difference compared with those without PsA. Receiver operator curves showed an area under the curve of 0.82 (95% CI 0.72, 0.92) for the total score. A cut-off value ≥36 showed sensitivity of 77.8%, and specificity of 82.3% for the diagnosis of PsA. Conclusion: The PACE questionnaire is simple and convenient screening tool for detecting PsA in Korean dermatologic clinic. Dermatologists should consider PASE questionnaire for psoriasis patients attending clinics, as it proved robust for the early identification of PsA.
( Hoon Soo Kim ),( Hyang Suk You ),( Won Jeong Kim ),( Hyun Ho Cho ),( Je Ho Mun ),( Marg Aret Song ),( Hyun Chang Ko ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Mohs micrographic surgery(MMS) is the most widely used treatment option for non-melanoma skin cancer(NMSC) because of very high success rate of complete excision. However, even MMS cannot guarantee a 100% chance of cure and there is risk of recurrence after MMS. Objectives: To analyze clinical and histologic data of cases of recurred NMSC after MMS and to understand characteristic features of recurred cases. Methods: Total of 17 patients, including 9 with basal cell carcinoma(BCC) and 8 with squamous cell carcinoma(SCC), recurred after MMS during 15 year period at Pusan National University Hospital. Previous treatment history, location of lesion, clinical and histologic subtype and data related to MMS were investigated. Results: Five patients with BCC and 4 with SCC had previous treatment history such as laser ablation and incomplete excision. In BCC group, 4 were located on periorbital area and 6 had aggressive histologic type. The average number of MMS stage, tumor size and length of surgical margin in study groups was more larger than that of total patient group treated with MMS at our hospital. The mean interval between operation and recurrence was 52 months in BCC group and 9 months in SCC groups. Conclusion: Based on our study, particular attention should be drawn to NMSC patients with previous treatment history, specific anatomical location such as periorbital area, and large tumor size to reduce the risk of recurrence after MMS.