Nanostructured Fe_xSb_yO_z Composites as Anode Materials for Sodium-Ion Batteries

Nguyen, Tuan Loi,Park, Sang Joon,Kim, Ji Hyeon,Kim, Il Tae American Scientific Publishers 2017 Science Of Advanced Materials Vol.9 No.9

<P> Nanostructured Fe<SUB>x</SUB>Sb<SUB>y</SUB>O<SUB>z</SUB> composites were developed via a galvanic replacement reaction. Two different galvanic replacement reaction times were used to control the morphology of the composite material. The structure, morphology, and composition of the as-prepared composites were characterized by X-ray diffraction, transmission electron microscopy, and energy dispersive X-ray spectroscopy. It was observed that the Fe<SUB>x</SUB>Sb<SUB>y</SUB>O<SUB>z</SUB> composites consisted of the Sb/Sb<SUB>2</SUB>O<SUB>3</SUB>/Fe<SUB>3</SUB>O<SUB>4</SUB> phases. When evaluated as anode materials for sodium-ion batteries, the composites exhibited a high coulombic efficiency, excellent cycling stability, and high rate capability. The excellent electrochemical performance of the composites could be ascribed to the synergistic effect involving conversion and alloying reactions between Sb/Sb<SUB>2</SUB>O<SUB>3</SUB>/Fe<SUB>3</SUB>O<SUB>4</SUB> and Na+ ions. Specifically, conversion reactions between Na+-ions and Sb<SUB>2</SUB>O<SUB>3</SUB> or Fe<SUB>3</SUB>O<SUB>4</SUB> generated amorphous Na<SUB>2</SUB>O and the inactive conductive phase of Fe, which could act as an effective buffer against volume changes during cycling, resulting in improved cycling performance. </P>

Recent advances in Alzheimer’s disease pathogenesis and therapeutics from an immune perspective

Nguyen Thai-Duong,Dang Loi Nguyen,Jang Jung-Hee,박소연 한국약제학회 2023 Journal of Pharmaceutical Investigation Vol.53 No.5

Background The prevalence of Alzheimer’s disease, the most common type of dementia, is continuously increasing. Many recent reports have indicated that immune-related mechanisms play a vital role in Alzheimer’s disease pathogenesis, such that the imbalance between the immune response and central nervous system leads to neuroinflammation. Area covered The inflammatory response in Alzheimer’s disease is a “double-edged sword”. Neuroinflammation protects neuronal cells in the initial stages of Alzheimer’s disease, while sustained inflammation promotes neurodegeneration. Alterations in the peripheral immune system, such as increased inflammation, lead to the activation of the central immune response, which in turn causes neuroinflammation and neuronal damage. Additionally, an imbalance between pro- and anti-inflammatory cytokines, which are secreted by the central and peripheral immune systems, induces complex immune responses and contributes to Alzheimer’s disease pathogenesis. In this review, we aimed to summarize our current knowledge of the role of the immune system in Alzheimer’s disease pathology. We performed an in-depth investigation on the contribution of each immune system component to Alzheimer’s disease progression at different disease stages. More importantly, we discuss novel immune-related therapeutic strategies for Alzheimer’s disease treatment currently being investigated via clinical trials. Expert opinion The scrutinized observations of immune responses in different brain regions at various stages of Alzheimer’s disease might help identify potential treatment strategies for Alzheimer’s disease. The modulation of immune components in the brain by targeting cytokines and other factors, which compromise immune response and neuroinflammation, is recommended as a promising alternative for Alzheimer’s disease treatment. Clinical trials are currently investigating the efficacies of numerous vaccines and monoclonal antibodies targeting amyloid beta peptide and tau protein for Alzheimer’s disease treatment. Moreover, aducanumab and lecanemab were approved by the Food and Drug Administration as monoclonal antibody-based drugs for Alzheimer’s disease treatment in 2021 and 2023, respectively. However, these drugs are effective only against mild symptoms due to the irreversible neuronal damage found in patients with Alzheimer’s disease progression. In addition, side effects including amyloid-related imaging abnormalities (such as vasogenic edema, microhemorrhages, and hemosiderosis) were reported in patients undergoing Alzheimer’s disease treatment using monoclonal antibodies. Thus, the future development of therapeutic agents for Alzheimer’s disease requires more sophisticated and multi-plunged approaches considering various biomarkers and immune landscapes characterizing the different stages of Alzheimer’s disease.

Facile Synthesis of quantum dots SnO₂/Fe₃O₄ hybrid composites for superior reversible lithium-ion storage

Nguyen, Tuan Loi,Hur, Jaehyun,Kim, Il Tae Elsevier 2019 Journal of industrial and engineering chemistry Vol.72 No.-

<P><B>Abstract</B></P> <P>Quantum dots SnO<SUB>2</SUB>/Fe<SUB>3</SUB>O<SUB>4</SUB> hybrid composites were synthesized by galvanic replacement reaction between Fe<SUP>3+</SUP> ions and Sn and were utilized as anodes for lithium-ion batteries. The composites at few-nanometer scale showed different compositions of SnO<SUB>2</SUB> and Fe<SUB>3</SUB>O<SUB>4</SUB> with different reaction time. The composites exhibited significantly enhanced electrochemical performance; for instance, SnO<SUB>2</SUB>/Fe<SUB>3</SUB>O<SUB>4</SUB>-18h electrode delivered a reversible capacity of 1300mAhg<SUP>−1</SUP> after 100 cycles and a rate capacity of 507mAhg<SUP>−1</SUP> at 10Ag<SUP>−1</SUP>. The notable performance was ascribed to the presence of quantum dots nanostructures and inactive phases and to the generation of a short Li<SUP>+</SUP>-ion diffusion pathway.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Quantum dots SnO<SUB>2</SUB>/Fe<SUB>3</SUB>O<SUB>4</SUB> are synthesized by galvanic replacement reaction. </LI> <LI> SnO<SUB>2</SUB>/Fe<SUB>3</SUB>O<SUB>4</SUB> hybrid composites are comprised of small nanoparticles (<6nm). </LI> <LI> SnO<SUB>2</SUB>/Fe<SUB>3</SUB>O<SUB>4</SUB> hybrid composites include void spaces acting as buffers during cycling. </LI> <LI> Presence of quantum dots and inactive phases leads to superior reversible Li-ion storage. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Iron-antimony-based hybrid oxides as high-performance anodes for lithium-ion storage

Nguyen, Tuan Loi,Kim, Doo Soo,Hur, Jaehyun,Park, Min Sang,Yoon, Sukeun,Kim, Il Tae Elsevier 2018 Journal of Power Sources Vol.389 No.-

<P><B>Abstract</B></P> <P>We report a facile approach to synthesize Fe-Sb-based hybrid oxides nanocomposites consisting of Sb, Sb<SUB>2</SUB>O<SUB>3</SUB>, and Fe<SUB>3</SUB>O<SUB>4</SUB> for use as new anode materials for lithium-ion batteries. The composites are synthesized via galvanic replacement between Fe<SUP>3+</SUP> and Sb at high temperature in triethylene glycol medium. The phase, morphology, and composition changes of the composites involved in the various stages of the replacement reaction are characterized using X-ray diffractometry, high-resolution transmission electron microscopy, and energy dispersive X-ray spectroscopy. The as-prepared composites have different compositions with very small particle sizes (<< 10 nm). The Fe<SUB>x</SUB>Sb<SUB>y</SUB>O<SUB>z</SUB>-18 h composite, for instance, exhibits high capacity, better cyclic stability, and rate performance than other composites, with a highly stable specific capacity of 434 mAh g<SUP>−1</SUP> at 500 cycles. The excellent electrochemical performance can be ascribed to the high interfacial contact area between the nanocomposite and electrolyte, stable structure of the composites owing to a mixture of inactive phases generated by the conversion reaction between Li<SUP>+</SUP> and oxide metal—whose structure serves as an electron conductor, inhibits agglomeration of Sb particles, and acts as an effective buffer against volume change of Sb during cycling—and high Li<SUP>+</SUP> diffusion ability.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Fe-Sb-based hybrid oxides are synthesized via galvanic replacement reaction. </LI> <LI> Fe<SUB>x</SUB>Sb<SUB>y</SUB>O<SUB>z</SUB> composites have nanoparticles consisting of crystalline Sb, Sb<SUB>2</SUB>O<SUB>3</SUB>, and Fe<SUB>3</SUB>O<SUB>4</SUB>. </LI> <LI> Fe<SUB>x</SUB>Sb<SUB>y</SUB>O<SUB>z</SUB> composites possess enough spaces functioning as buffers during lithiation. </LI> <LI> Formation of active and inactive phases leads to enhanced electrochemical performances. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Cu–SnO₂ nanostructures obtained via galvanic replacement control as high performance anodes for lithium-ion storage

Nguyen, Tuan Loi,Park, Duckshin,Hur, Jaehyun,Son, Hyung Bin,Park, Min Sang,Lee, Seung Geol,Kim, Ji Hyeon,Kim, Il Tae Elsevier BV * North-Holland 2018 Applied Surface Science Vol.429 No.-

<P><B>Abstract</B></P> <P>SnO<SUB>2</SUB> has been considered as a promising anode material for lithium ion batteries (LIBs) because of its high theoretical capacity (782mAhg<SUP>−1</SUP>). However, the reaction between lithium ions and Sn causes a large volume change, resulting in the pulverization of the anode, a loss of contact with the current collector, and a deterioration in electrochemical performance. Several strategies have been proposed to mitigate the drastic volume changes to extend the cyclic life of SnO<SUB>2</SUB> materials. Herein, novel composites consisting of Cu and SnO<SUB>2</SUB> were developed via the galvanic replacement reaction. The reaction was carried out at 180 <B>°</B>C for different durations and triethylene glycol was used as the medium solvent. The structure, morphology, and composition of the composites were analyzed by X-ray diffraction, transmission electron microscopy, and energy dispersive X-ray spectroscopy. The reaction time affected the particle size, which in turn affected the reaction kinetics. Furthermore, the novel nanostructures contained an inactive metal phase (Cu), which acted both as the buffer space against the volume change of Sn during the alloying reaction and as the electron conductor, resulting in a lower impedance of the composites. When evaluated as potential anodes for LIBs, the composite electrodes displayed extraordinary electrochemical performance with a high capacity and Coulombic efficiency, an excellent cycling stability, and a superior rate capability compared to a Sn electrode.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cu–SnO<SUB>2</SUB> nanostructures can be controlled by reaction time of galvanic replacement reaction. </LI> <LI> The Cu–SnO<SUB>2</SUB> composites show better cyclability compared to Sn. </LI> <LI> The Cu–SnO<SUB>2</SUB> composite anode demonstrates extraordinary electrochemical performance. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Key Factors Affecting Sustainable Tourism in the Region of South Central Coast of Vietnam

NGUYEN, Cong De,NGO, Thang Loi,DO, Ngoc My,NGUYEN, Ngoc Tien Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.12

Sustainable tourism is the development of tourism activities to meet the current needs of tourists and indigenous peoples while paying attention to the conservation and improvement of resources for the development of tourism activities in the future (World Tourism Organization, 2013). With the aim of identifying factors affecting the development of sustainable tourism in the South Central Coast of Vietnam, the study conducted a typical survey of 160 tourism managers and 240 tourists traveling or have participated in tourism activities of 8 provinces in the South Central Coast of Vietnam, and used the exploratory factor analysis (EFA) analysis and regression analysis for analyzing the data. The research results show that 11 factors impact the development of sustainable tourism in the South Central Coast namely Institutions and policies for tourism development, Infrastructure, Tourism resources, Human resources for tourism, Diversity of tourism services, Relevant support services, Activities of association and cooperation for tourism development, Tourism promotion and encouragement, Tourists' satisfaction, Local community, and Other factors. At the same time, among the above factors, the factors Institutions and policies for tourism development, Infrastructure, Tourism resources, and Local community strongly impact the development of sustainable tourism in the region.

A novel methanotroph in the genus Methylomonas that contains a distinct clade of soluble methane monooxygenase

Ngoc-Loi Nguyen,유운종,양혜영,김종걸,정만영,박수제,노성운,이성근 한국미생물학회 2017 The journal of microbiology Vol.55 No.10

Aerobic methane oxidation is a key process in the global carbon cycle that acts as a major sink of methane. In this study, we describe a novel methanotroph designated EMGL16-1 that was isolated from a freshwater lake using the floating filter culture technique. Based on a phylogenetic analysis of 16S rRNA gene sequences, the isolate was found to be closely related to the genus Methylomonas in the family Methylococcaceae of the class Gammaproteobacteria with 94.2–97.4% 16S rRNA gene similarity to Methylomonas type strains. Comparison of chemotaxonomic and physiological properties further suggested that strain EMGL16-1 was taxonomically distinct from other species in the genus Methylomonas. The isolate was versatile in utilizing nitrogen sources such as molecular nitrogen, nitrate, nitrite, urea, and ammonium. The genes coding for subunit of the particulate form methane monooxygenase (pmoA), soluble methane monooxygenase (mmoX), and methanol dehydrogenase (mxaF) were detected in strain EMGL16-1. Phylogenetic analysis of mmoX indicated that mmoX of strain EMGL16-1 is distinct from those of other strains in the genus Methylomonas. This isolate probably represents a novel species in the genus. Our study provides new insights into the diversity of species in the genus Methylomonas and their environmental adaptations.

Facile Synthesis of quantum dots SnO2/Fe3O4 hybrid composites for superior reversible lithium-ion storage

Tuan Loi Nguyen,허재현,김일태 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.72 No.-

Quantum dots SnO2/Fe3O4 hybrid composites were synthesized by galvanic replacement reactionbetween Fe3+ ions and Sn and were utilized as anodes for lithium-ion batteries. The composites at few-nanometer scale showed different compositions of SnO2 and Fe3O4 with different reaction time. Thecomposites exhibited significantly enhanced electrochemical performance; for instance, SnO2/Fe3O4-18 h electrode delivered a reversible capacity of 1300 mAh g 1 after 100 cycles and a rate capacity of507 mAh g 1 at 10 A g 1. The notable performance was ascribed to the presence of quantum dotsnanostructures and inactive phases and to the generation of a short Li+-ion diffusion pathway.

Factors Affecting FDI Intentions of Investors: Empirical Evidence from Provincial-Level Data in Vietnam

Van Loi TA,Anh Duc DO,To Uyen PHAN,Quang Huy NGUYEN,Thi Thuy Hong NGUYEN,Thuy Duong LE,Thanh Phong NGUYEN 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.4

This study aimed to explore the factors affecting the foreign direct investment (FDI) intentions of investors into Quang Ninh province, located in the north-eastern of Viet Nam. Researchers used two main methods, namely, Exploratory Factors Analysis (EFA) and the Structural Equation Model (SEM) based on partial least squares structural equation modeling (PLS SEM) to explore and measure the impact of factors affecting the investors’ FDI intentions into Quang Ninh province. The empirical analysis used data from the survey of 206 domestic and foreign investors into Quang Ninh province, including representatives of the Board of Directors, members, and management representatives at the department level, with reliable tools (SPSS 26 and SmartPLS 3.0 software). The research results identified the following factors affecting investment into Quang Ninh: FDI attraction policies have the strongest impact on the investors’ FDI intentions; it is followed by infrastructure, public services and human capital with strong effects on intentions of investors’ FDI; and finally the standards of living that affects the investors’ FDI intentions. There is also a positive relationship between all the factors and the investors’ FDI intentions. Several recommendations are further suggested to enhance attraction of foreign direct investment into Quang Ninh province.

Acid adaptation of methane oxidation

Ngoc-Loi NGUYEN,Woon-Jong Yu,Samuel Imisi Awala,Lorraine Bellosillo,Sung-Keun RHEE 한국생물공학회 2019 한국생물공학회 학술대회 Vol.2019 No.4