심근 허혈-재관류 백서 모델에서 mitogen-activated protein kinase 활성화에 대한 α-lipoic acid의 효과

김연경,박은미,최준호,윤경호,유남진,이은미,김남호,정진원,김민선,박병림,오석규 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

관상동맥 스텐트 삽입술을 시행한 환자에서 안지오텐신 전환효소 억제제와 안지오텐신 수용체 차단제가 재협착에 미치는 영향

김연경,정진원,윤경호,박은미,송미진,최준호,이은미,유남진,김남호,오석규 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

정상체중군과 과다체중군 산업장 중간관리자의 건강증진 행위에 관한 비교연구

김정남(Kim Chung Nam),박경민(Park Kyung Min),류미경(Ryu Mi Kyung),장희정(Jang Hee Jung) 계명대학교 간호과학연구소 2001 계명간호과학 Vol.5 No.1

The purpose of this study was to identify and compare Health Promoting Behavior and its affecting factors between Normal and Over weight industrial middle manager. The subjects were 163 workers employed in factories in Taegu and Kyung-book were convenient sampling data the period for May 22th-26th, 2000 through self report methodby structured questionnaires. Collected data were analyzed by t, x2, Kendal tau, Pearson correlation, Stepwise Multiple Regression. The results of this study were as follows. 1. There were a significant difference in shift pattern(x2=7.89, P=0.005) and career. (x2=12.99, P=0.005) between normal weight and overweight group. 2. The average score of performance in health promoting behavior among overweight group(2.55) was higher than that of normal weight group(2.46), but not significant. 3. The average score of health status in overweight group(3.07) was lower than that of normal weight group(3.21), but not significant. 4. The average score of self-efficacy in overweight group(3.63) was significant lower than that of normal group(3.71). 5. The average score of the perceived barrier of in overweight group(2.44) was significant higher than that of normal group(2.24). 6. Health promoting behaviors in overweight group was significantly correlated with health status(r=.384, P<.05), health Concept(r= 458, P<.01) self-efficacy ( r=352, P< 01), perceived benefit(r=.386, P< .05), perceived barrier(r= -245, P< .05) Health promoting behavior in normal weight group was significantly correlated with health concept( r= .307, P< .050 and perceived benefit. 7. In consideration of variables that have an influence on Health promoting behavior among Normal weight group, health concept and perceived benefit account for 28.8% of health promoting behavior. In overweight group. The perceived benefit account for 13.7% of health promoting behavior. The suggestions are as follows on the basis of the results of this study. 1. It is required to develop health promoting program to improve health promoting behavior. In addition, there are special demands on developing nursing strategies for health promoting behavior of overweight industrial supervisors. 2. It is necessary to support exercise facility in occupational field for improving supervisor's health promoting behavior.

급성 관동맥증후군 환자의 신기능 이상과 주요 심장사건과의 관계

이상재,윤경호,최준호,송미진,김연경,박은미,김현정,이은미,유남진,김남호,오석규,정진원 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

환기정도에 따른 수술실용 신발 종류가 수술실 오염에 미치는 영향 : How to Choose Suitable Shoes?

남경동,정혜선,박영신,원진희,주미자,성화신,이지혜,이병희,조경숙,배재춘 한국의료QA학회 2000 한국의료질향상학회지 Vol.7 No.1

Background : Various types of protective footwear have been used to minimize bacterial contamination in operating rooms. In recent years, debate has arisen concerning the need for use of such protective footwear. This study was designed to provide useful data about choosing shoes most suitable for the surgical environment. Methods : Between November, 1999 and January, 2000, we performed this experimental study by comparing effect of three types of shoes (i.e., disposable shoescover, operating room-restricted shoes, and ordinary shoes) on bacterial contamination of operating rooms equipped with two different ventilation systems (i.e., high air-change, low air-change) respectively. Data were collected during two-hour sham operations in which subjects and their activities were strictly standardized. Bacterial flora were sampled from the study area floor and air colony-counts were measured. Results : In experiments involving high air-change ventilation system, there was a significant difference of floor contamination between three types of shoes, but no difference of air contamination. Under low air-change system, there was a significant difference of both floor and air contamination between three types of shoes. Conclusion : The results show that protective footwear would be unnecessary in the operating room with high air-change ventilation system, but it is important to choose suitable shoes carefully under low air-change system. Therefore, the use of outdoor shoes can be considered under high air-change system, but it would seem sensible to apply their first use in less bloody operations at the day surgery center or out-patient department to prevent transfer of body fluid into the outside environment.

경기지역 일부 초등학생의 건강관련습관 및 음식기호도에 관한 연구

남미성,송경희 명지대학교 자연과학연구소 2004 자연과학논문집 Vol.23 No.-

본 조사는 초등학생의 건강관련 습관 및 음식에 대한 기호도를 연구하고자 경기도의 초등학교 어린이 524명(남자 265명, 여자 259명)을 대상으로 실시되었다. 저체중군은 32.8%, 정상체중군은 36.7%, 과체중군은 30.5%이며 남자아동이 52.5%로 여자아동 47.5% 보다 과체중군이 많았다. 과체중군이 신장, 체중, 비만도, BMI, RI가 저체중군이나 정상체중군에 비해 현저히 높은 값을 나타내어 유의적으로 높았다. 체중은 비만도, BMI,RI와 유의적인 양의 상관관계가 있었다. 아침식사에 대한 규칙성 조사결과 55.9%의 아동이 매일 아침 식사를 하고 있으며, 아침식사의 내용은 88.9%의 아동이 밥을 먹고 있는 것으로 나타났다. 식사에 소비되는 시간은 11~20분이 43.3%로 가장 많았으며, 남자아동이 여자아동보다 현저히 음식을 빠르게 먹는 경향을 보였다(p<.001). 대부분의 아동이 식사량은 적당히 먹고 있는 것으로 조사되었다. 하루에 간식은 2~3회 하고 있으며, 주로 아이스크림과 과자류를 선호하는 경향을 보였다. 음식의 기호도 조사결과 밥류에서는 흰쌀밥과 현미밥, 보리밥을 선호하였으며 국 · 탕 · 찌개류에서는 쇠고기미역국, 참치김치찌개, 맑은 미역국, 설렁탕 순으로 선호하였다. 남자아동이 여자 아동보다 삼계탕, 해물탕, 육개장을 유의성 있게 선호하였으며(p<0.05), 콩비지찌개는 여자 아동이 남자 아동보다 유의성 있게 선호하였다(p<0.05). 김치류에서는 배추김치, 오이김치, 열무김치순으로 선호하였다. This study was carried out to investigate health-related lifestyle and food preference of elementary school children. A survey was conducted with 520 healthy children (265 males and 259 females) from 4th grade to 6th grade in elementary school. According to the Obesity Index, 52.5% of boys were overweight, which was higher than 47.5% of girls. Overweight group had height, weight, BMI, Obesity Index, and RI significantly higher values than the other two groups (p < 0.001). Fifty-sixpercent of children reported that they reguarly consumed breakfast, and among them 88.9% answered rice as their main breakfast food. Time spent eating was 11~20 minutes where boys ate faster than girls (p < 0.001). Majority of children considered themselves eating moderate amounts for each meal. Their snack consumption was 2~3 times a day, with highest preference for ice cream. Their most favorite food were Ssalbap in rices, Soegogi-miyeokguk in guks, and Baechuk-kimchi in kimchis.

FGF-mediated FGFR signaling 이 두개봉합부의 초기형태발생 및 유지기전에 미치는 영향

남순현,김영진,서경환,김현정,박미현,유현모 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.4

두개봉합부의 조기융합으로 알려진 Craniosynostosis는 두개봉합부 주위 조직들 사이의 조화로운 상호 작용이 파괴되었을 때 야기될 수 있다. 흥미롭게도 FGF receptor들, 특히 FGFR2의 point mutation은 여러 가지 형태의 craniosynostosis 증후군과 연관되어 있어, FGFR가 두개봉합부를 포함한 두개골 성장 발달과정에 중요한 유전자임을 시사하고 있다. Mouse 두개봉합부의 초기형태발생시 FGFR 유전자들의 기능을 알아보기위해, in situ hybridization 방법을 이용하여 FGFR2(BEK) 및 골아세포분화의 초기표지자인 osteopontin이, 태생기(E15-18)에서 출생후(P1-P3)까지, 두개골의 시상봉합부에서의 발현양상을 조사하였다. FGFR2(BEK)은 osteogenic front에 강하게 발현되었으며, osteopontin은 parietal bone의 exo-, endocranial부위에서 발현되었으나, parietal bone의 성장가장자리인 osteogenic front에서는 관찰되지 않았다. 두개봉합부에서의 FGF-mediated FGFR signaling의 역할을 좀더 심도깊게 조사 하기위해 E15.5 mouse의 두개골을 이용하여 in vitro 실험을 시행하였다. 흥미롭게도 osteogenic fronts 및 시상봉합부의 간엽조직 중앙에 FGF2 - soaked beads를 점적하여 36시간 기관배양한 결과, bead주위 조직들의 두께 및 세포수가 증가되었으며, osteogenic fronts 상에 FGF4 beads를 올려놓은 경우, 시상두개봉합부 중앙에 점적된 FGF4 beads나 BSA control beads에 비해, 골성장이 촉진되어 시상두개봉합부의 부분적인 소멸을 관찰할 수 있었다. 이와 더불어 FGFR2 beads는 osteopotin 및 Msxl 유전자의 발현을 유도하였다. 이 결과들을 종합해 볼 때, FGF - mediated FGFR signaling이 발육중인 두개골과 두개봉합부에서 세포의 증식과 분화의 균형을 조절하는데 중요한 담당하고 있음을 시사해주고 있으며, 이 과정중 FGF signaling이 osteopontin 및 Msxl 유전자의 발현을 조절하므로써 막내골 성장 및 두개봉합부의 유지기전에 기여할 것으로 사료된다. Craniosynostosis, the premature fusion of cranial sutures, presumably involves disturbance of the interactions between different tissues within the cranial sutures. Interestingly, point mutaions in the genes encoding for the fibroblast growth factor receptors(FGFRs), especially FGFR2, cause various types of human craniosynostosis syndromes. To elucidate the function of these genes in the early morphogenesis of mouse cranial sutures, we first analyzed by in situ hybridization the expression of FGFR2(BEX) and osteopontin, an early marker of osteogenic differentiation, in the sagittal suture of calvaria during embryonic (E15-E18) and postnatal stage (P1 - P3). FGFR2(BEK) was intensely expressed in the osteogenic fronts, whose cells undergo differentiation into osteoprogenitor cells that ultimately lay down the bone matrix. Osteopontin was expressed throughout the parietal bones excluding the osteogenic fronts, the periphery of the parietal bones. To further examine the role of FGF-mediated FGFR signaling in cranial suture, we did in vitro experiments in E15.5 mouse calvarial explants. Interestingly, implantation of FGF2 soaked beads onto both the osteogenic fronts and mid-mesenchyme of sagittal suture after 36 hours organ culture resulted in the increase of the tissue thickness and cell number around FGF2 beads, moreover FGF4-soaked beads implanted onto the osteogenic fronts stimulated suture closure due to an accelerated bone growth, compared to FGF4 beads placed onto mid-mesenchyme of sagittal suture and BSA control beads. In addition FGF2 induced the ectopic expression of osteopontin and Msxl genes. Taken together, these data indicate that FGF-mediated FGFR signaling has a important role in regulating the cranial bone growth and maintenance of cranial suture, and suggest that FGF-mediated FGFR signaling is involved in regulating the balance between the cell proliferation and differentiation through inducing the expression of osteopontin and Msxl genes.

자료포락분석(DEA)를 이용한 보건의료의 효율성 측정

김남송,박홍섭,김은진,김설화,김정숙,김현아,김경숙,신지혜,최은정,양은진,유선미,유수진 圓光大學校 醫科學硏究所 2007 圓光醫科學 Vol.22 No.1

근골격계 환자에서 간호중재 빈도분석

權敬男,李美景 영남이공대학 1999 論文集 Vol.28 No.-

The purpose of this study was to survey and identify the nursing intervention performed by the orthopedic nurses from 2 university hospital in Taegu. The sample consisted of 30 nurses had worked 1 year in orthopedic unit. For this study, I used the Nursing Intervention questionnare developed by the Iowa Intervention project and translated by korean specialists and professors concerned to the same field. In order to obtain the data, a special group of 4 head nurses, professor, and researcher was instituted. the special group work validated 201 nursing interventions with agreement of more than 50% because the NIC(433 nursing intervention) survey process was too time-consuming and not appropriate for all labels. The data were collected from June 1 to July 4, 1999 and analysed with SAS program. The obtained results are as follows; (1) 32 interventions were performed at least daily. The most frequently used nursing interventions were Ⅳ Insertion, Ⅳ Therapy, Parenteral Medication Administration, Analgesic Administration, Medication Administration, Pressure Ulcer Prevents, and Pain Management in rank. he next interventions were rarely used: Postmortem Care, Dying Care, Resuscitation, Sucide Prevention, Seclusion in rank. In conclusion, this survey using NIC has helped to figure out the component of the orthopedic care in Korea. The use of this results will contribute to enhance quality assessment and improve the standard of orthopedic nursing.

누구를 위한 POCT인가?

조경진,이창규,이승관,정희천,김미숙,남경미,전주임 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.2

Patient-oriented minds and Bill of Rights have brought a lot of POCTs or Waived Tests, which can obviously be threats to the medical technology profession. However, we cannot help but admit the realities and should take some necessary measures to meet the situation. Accordingly we took a survey to find what opinions medical scientists or nurses have against the POCTs. Most of the scientists worried about the reliabilites of test results while nurses were concerned about the ambiguity of their job entities. Taking account of the POCT nature, the scientists should lead the development of POCT menus and have the primanry responsibility to educate or train the POCT perfomers maitaining periodic QCs on all the procedures or equimpments, not paying much attention to the issues who might be the performers.