흉선종 제거후에 발생한 재생 불량성 빈혈 : 증례보고

전원선,이상철,김현정,배상병,김찬규,이남수,박노진,이규택,박성규,홍대식,박희숙,원종호 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

Thymoma is associated with myasthenia gravis, Pure red cell aplasia, and autoimmune diseases such as autoimmune hemolytic anemia, aplastic anemia, and hypogammaglobulinemia. It's association with aplastic anemia is rare and aplastic anemia appearing after surgical removal of thymoma is especially rare. The authors hereby report a case of aplastic anemia occuring in a patient who was diagnosed with thymoma and myasthenia gravis and had the tumor surgically removed. The patient was treated with anti-thymocyte globulin, cyclosporin, and prednisolone, and showed partial remission with hematologic improvements after 12 months.

재발 또는 불응성 비호즈킨 림프종 환자에서 CDME 구제항암화학요법 후 고용량 항암화학요법 및 자가말초혈액 조혈모세포이식의 효과

김세형,한강원,배상병,김찬규,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Background and objectives : The long-term survival in patients with non-Hodgkin's lymphoma (NHL) after conventional dose chemotherapy is about 35% and the rest of the patients tend to have relapse. So, in relapsed or refractory NHL, we compared the outcome of patients undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation(APBSCT) with only salvage chemotherapy of cisplatin, dexamethasone, mitoxantrone, and etoposide(CDME). Materials and methods : From June 1993 to December 1999, 25 patients with relapsed or resistant NHL were treated with CDME regimen as salvage chemotherapy. Twelve patients were received four cycles of CDME chemotherapy, and 13 patients were received high-dose chemotherapy with APBSCT following two cycles of CDME chemotherapy. Results : The median follow-up duration was 12.8 months(range:4-68). The overall response rate was 41.7% (complete response rate 25%, partial response rate 16.7%) in 12 patients with CDME only. Thirteen patients who were treated with high-dose chemotherapy with APBSCT achieved 61.5% complete response rate and 15.4% partial response rate, with an overall response rate of 76.9%. The estimated 3-year progression-free survival rate was significantly higher among patients who received high-dose therapy than patients who received CDME only(41.5% vs 20.0%, p<0.05). And, 3-year overall survival rate was significantly higher among patients who received high-dose therapy(51.3% vs 25.0%, p <0.05). Conclusions : In relapsed or refractory NHL, CDME chemotherapy is an effective salvage chemotherapy and allow peripheral blood stem cell collection. Also, high-dose chemotherapy with APBSCT following CDME is superior to CDME salvage chemotherapy only.

조혈모세포이식환자에서 조혈기능의 회복과 관련된 인자들에 관한 연구

정기주,강명수,권기두,김경하,이상철,김현정,배상병,김찬규,이남수,이규택,원종호,홍대식,박희숙 순천향대학교 의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

..

固體還元劑에 의한 酸洗廢葉物인 酸化鐵의 充塡層 還元

李大喆,李圭澤 全北大學校 1979 論文集 Vol.21 No.-

In the manufacturing process for obtaining reduced sponge iron from pickling-oxide, the production of sponge iron is strictly controlled by pre-reduction process of the pickling oxide bed by coal coke and anthracite. Consequently for the increased of this product, the fundamental knowleadge of a reduction mechanism of the packed bed has to be reviewed. In this study, time dependences of fractional reduction R for a packed columnar iron oxide bed at 1100℃ were measured for various kind of iron oxides with various particle size, using reducing agents, coal coke and anthracite. Fractional reduction R is measured for ratio of outer diameter of unreacted part r_0 and that of sponge iron r, R=1-(r r_0)^2.

中國外債硏究

李圭澤 한국중국문화학회 2002 中國學論叢 Vol.14 No.-

인터넷 메타데이타 검색 및 관리 시스템의 설계 및 구현

이원석,박경용,양영종,정효택,김순용,이규철 한국문헌정보학회 1997 한국문헌정보학회지 Vol.31 No.2

인터넷은 디지탈 형태의 다양한 정보를 신속하게 전달한다는 점에서 매우 각광을 받고 있다. 그러나, 대량의 인터넷 정보 중에서 자신이 원하는 정보 자원을 정확하게 많이 얻어 낼 수 있는 방법의 제공은 매우 어려운 문제이다. 본 논문에서는 인터넷 정보 자원의 메타데이타를 관리하기 위해 SeriCore라는 SGML 형식의 메타데이타 DTD(Document Type Definition)를 정의하고, 이들 메타데이타를 효율적으로 저장하고 검색, 관리할 수 있는 시스템을 설계, 구현하였다 The Internet has gained popularity because ot provides various information in digital format. However, it is very difficult to provide methods which make it possible to search adequate information resource from bulk of Internet information. In this paper, we define a SGML metadata DTD, named SeriCore, and design and implement a metadata retrieval and management system which can store, retrieve and manage the Internet metadata efficiently

12주간의 써키트 웨이트트레이닝이 중ㆍ장년기 남성의 건강관련체력에 미치는 영향

이규성,김문희,오경택,김범수 한국체육대학교 체육과학연구소 2000 韓國體育大學校附屬 體育科學硏究所論文集 Vol.19 No.1

The purpose of this study is to examine the change of health related physical fitness. The study conducted the experiment with 24 participants; three groups fo eight participants in each age group(40, 50 and 60's) The subjects are members of the G sports center. The results of this study are as followed. According to comprehensive results of the research, circuit weight training for 12 weeks appears to give a positive effects on middle aged men's health, and that large increase in body fat and lower strength is not an unavoidable result of aging but the result of an unhealthy life style. Putting the proper training for the middle-aged group into systematic and regular practice, exercise can delay the normal aging process and also maintain relative good health physiologically. I think we need to develop more rational and scientific exercise programs to build up physical strength and improve health.

식품과 식품포장재 중 첨가물 및 중금속 함량에 관한 연구

李丙晁,朴澤奎 건국대학교 1980 學術誌 Vol.24 No.2

A study was carried out on the coloring matters, preservatives and color fixation matters in hall and sausage sampled from 5 companies during the period of two months from August 1, to October 1, 1979, and determined the contents of cadmium and Lead in food packaging materials (PVC) The results were obtained as follows. (1)In ham a mixture of Amaranth and Tartrazine was detected in three (10%), and Amaranth was detected in two (5%) that of Amaranth, Tartrazine and Sunset yellow FCF in one (3.3%) (2)In sausage a mixture of Amaranth auld Tartrazine was found ill 11 (36.7%) that of Amaranth and Sunset Yellow FCF in 9 (30%), Amaranth in 4 (13.3%), Tartrazine 3 (10%) of 30 samples. (3)In ham a mixture of solbic acid and its salts, AF2 was detected in 11 (36.7%) and a mixture of sorbic acid, its salt, AF2 and Nitrofurazone was detected in 9 (30 %) out of 30 samples and that in sausage was a mixture of sorbic acid, its salts and AF2 in 14 (46.7%) and a mixture of sorbic acid, its salt and Nitrofurazone was in 11 (36.7%) out of 30 samples. (4)The concentrations of all the color fixation matter were in the range of 480mg to 2730mg per Kg of samples in ham and of 410mg to 2700mh in sausage (5)The contents of Cadmium and Lead in PVC packaging materials were in the range of 120.5 ㎍/g to 515.3 ㎍/g and 257 ㎍/g to 1.593 ㎍/g respectively.

폐색전증을 동반한 고환혼합생식세포종양 1례

이규택 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

A 30-year-old male presented with dyspnea and chest pain. Rt radical orchiectomy revealed mixed germ cell tumor and he was diagnosed with stage IV testicular cancer. Mixed germ cell tumor in testis is a rare tumor. Cure rate in ealy stage testicular cancer was above 90% but prognosis in late stage is not good. In three cycles of chemotherapy, β-hCG was not detected in serum, but the lung lesions were seen in the chest X-ray. We recognized that further treatment modalities needed.

세포질내 정자주입법(ICSI)에 있어서 정자흡입 및 난자내 주입방법에 관한 연구

이택후,김항진,송건호,김대근,전상식,박윤규,서태광,전병균,류은경,이은숙,문진수,김광철 경북대학교 의학연구소 2000 경북대학교병원의학연구소논문집 Vol.4 No.1

Study on Method of Sperm Aspiration and Injection into an Oocyte in Intracytoplasmic Sperm Injection(ICSI) Immobilization of spermatozoa prior to intracytoplasmic sperm iniection(ICSI) sometimes results in crooked tail and this makes it difficult to aspirate sperm into an injection pipette tail first. Head-first sperm aspiration into an injection pipette avoid this problem due to the bigger size of the sperm head. The effect of head or tail-first sperm injection into an oocyte on fertilization cleavage, percentage of grade I embryos and development to blastocyst stage in ICSI program has been studied. A single living immobilized spermatozoa from oligoasthenozoospermic patient was injected into an oocyte head-first or tail-first according to the treatment. Eighteen hours after microinjection, oocytes ware inspected for survival and fertilization Fertilized oocytes with two pronuclei were cultured in 30μl drop of mHTF supplemented with 10% heat-inactivated follicular fluid(FF) at 37℃. On day 2. embryo transfer was performed with cleaved embryos. The remaining 2-8 cell stage embryos were co-cultured with BRL cells in mHTF + 10% FF for 72 hours and the developmental stage was observed. The data were analyzed by Analysis of Variance. A total of 164 oocytes from 36 cycles were assigned to earth treatment and ICSI was performed(88 head-first, tail-first). The rates of normal fertilization were 81.8% and 76.3% for head-first and tail-first, respectively. Of the fertilized oocytes, the percentage of cleaved embryos and the percentage of grade 1 embryo among cleaved embryos were 88.9% and 68.8%, 93.1% and 74.1% for head-first and tail-first, respectively. Of the 2-8 cell embryos cultured, 44.4%(16/36) and 50.0%(10/20) for head first and tail first, respectively developed to blastocyst stage. There were no differences in fertilization, cleavage, rates of grade 1 embryos, and development to blastocyst stage. In conclusion, head-first or tail-first sperm injection into an oocyte in ICSI program does not affect fertilization and subsequent embryo development to blastocyst stage in vitro.