서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

신경회로망을 이용한 서보밸브 유압실린더-부하계의 위치제어

趙勝鎬,黃雲奎 弘益大學校 科學技術硏究所 2001 科學技術硏究論文集 Vol.12 No.-

The open loop response of a single-rod linear actuator controlled by an electro-hydraulic servovalve is investigated for unloaded conditions by applying the self-excited identification method. A quasi model reference control approach is proposed for adapting the controller structure to variations in system parameters. The Neural network is trained off-line and on-line respectively by simulation and the effectiveness of this method is verified through real-time experiment. Experimental results of Artificial Neural Network control method are also compared with those of PD control method.

아드레날린 수용체 중개에 의한 Catecholamine의 Synaptosome을 통한 칼슘 이동의 조절

조성진,이정수,신용규,이광수 중앙대학교 의과대학 의과학연구소 1988 中央醫大誌 Vol.13 No.1

The presynaptic α-adrenoceptors medicate a negative feedback mechanism which leads to inhibition of neurotransmitter release probably by restricting the calcium available for the excitation-secretion coupling. It is reported that norepinephrine may shorten the duration of plateau phase in action potential by decreasing a voltage sensitive, slow inward calcium current and this action of norepinephrine is antagonized by α-adrenergic blocking agents. It is also suggested that there is a direct linkage between adrenoceptors and Na+-K+ ATPase. In the present study, therefore, effects of norepinephrine, dopamine an 5-hydroxytryptamine on the calcium uptake, Na+-Ca++ exchange and membrane potential in rat brain synaptosomes were investigated. The actions of neurotransmitters on the regulators for cellular calcium transport were also studied by investigation effects of catecholamines on synaptosomal Na+-k+ ATPase, Ca++ ATPase and Na+-Ca++ ATPase activities with or without adrenergic blocking agents. In the reaction mixture containing calcium without potassium, the addition of ATP induced the synaptosomal calcium uptake only slightly. The further addition of potassium is followed by a marked increase in calcium uptake with concomittent development of membrane depolarization. Amounts of calcium uptake were increased with increasing concentrations of potassium but decreased in the presence of extracellular sodium. Norepinephrine, dopamine and 5-hydroxytryptamine inhibited the potassium induced calcium uptake but had no effect on membrane potential. Na+-K+ ATPase, Mg++ ATPase and Ca++ ATPase activities were stimulated by these amines and stimulatory effects of catecholamines were antagonized by phentolamine and propranolol. Ouabain enhanced potassium induced calcium uptake but significantly inhibited Na+-K+ ATPase activity. Diltiazem and dibucaine effectively inhibited the depolarization induced calcium uptake, but had a variable effects on ATPase activities. Dibucaine significantly inhibited Ca++ ATPase. Among various agents tested, dibucaine alone was shown to slow down the development of membrane depolarization. Norepinephrine, dopamine and 5-hydroxytryptamine inhibited both the sodium dependent calcium efflux and Na+-Ca++ ATPase activity. The inactivation of Na+-CA++ ATPase by catecholamines was reversed by phentolamine and propranolol. These results suggest that there is a linkage between presynaptie adrenoceptors and regulatory apparatus for calcium transport across the synaptic membrane. Catecholamines appear to inhibit the calcium transport by the indirect effect on the ATPases, particulary Na+-K+ ATPase at plasma membrane which is mediated by adrenoceptors and also by possible action on the calcium conductance mechanism. On the other hand, adrenergic agonists may affect the Na+ dependent Ca++ efflux in synaptic membranes.

Goal-based Scenarios (GBS) 모형을 적용한 웹기반 교육용 컨텐츠의 설계 및 개발 연구

조규락,조영환,김미경,성봉식 한국컴퓨터교육학회 2004 컴퓨터교육학회 논문지 Vol.7 No.5

인터넷이라는 새로운 IT기술을 교육현장에서 적극적으로 활용해야 한다는 강한 요구에도 불구하고 웹기반 교육의 정착은 미흡한 실정이다. 그 원인은 현재 웹기반 교육이 전통적 교실수업과 질적으로 다르지 않고 웹기반 교육에 적합한 설계모형들이 충분히 개발되지 않았기 때문이다. 본 연구자들은 구성주의 학습관에 기반한 GBS 설계모형을 이용하여 도서관 이용에 관한 웹기반 교육용 컨텐츠를 개발함으로써 웹기반 교육을 개발하거나 활용하고자 하는 교사와 교육실천가들에게 구체적인 개발사례를 제공하고자 한다. 3개월 간 요구분석, 학습내용분석, 학습자 및 학습환경분석을 통해서 GBS모형을 적용한 웹기반 교육용 컨텐츠를 설계하고 GBS의 7가지 구성요소들에 충실하게 개발하였다. 본 연구의 결과들은 학교와 기업에서 새로운 형태의 웹기반 교육을 개발하고자 하는 실천가들에게 구체적인 가이드를 제공해줄 것이다. In spite of the strong request that Internet, a new IT technique, should be extensively used in classroom settings, WBI is not still wide spread. One possible reason is that most WBIs developed so far are not qualitatively different from the traditional classroom ones and various design models for WBI are unknown. Developing a WBI program according to Goal-based Scenarios (GBS), a constructivistic instructional design model, this study offers a useful case for the design and development of WBI to educators and implementers. The program developed embodied seven important components of the GBS model. The development process also included needs assessment, task analysis, and learner and environment analysis, which are the basic components of the domain of instructional design. The GBS development case in this article will provide concrete guidelines to educational practitioners who have an intention to create a new type of WBI in schools as well as in corporate.

Cerebral Arteritis

황성규,조수호 慶北大學校 醫科大學 1981 慶北醫大誌 Vol.22 No.1

The angiographic changes and causes of cerebral arteritis are presented. At any way, cerebral arteris is very rare condition, but we experienced 3 cases recently. There are observed spasm, vasodilatations, acclusion, cerebral infaction, extremely slow arteriovenous circulation time and collateral blood supply. Literatures were reviewed. But still we have a question and need further evaluation about long use of contraceptive pills could be a cause of cerebral arteritis or not.

新鮮 채소류의 Plastic film 包裝材에 關한 硏究

閔龍圭,朴相旭,趙光衍 충북대학교 농업과학기술연구소 1987 農業科學硏究 Vol.5 No.1

In order to determine shelf life and proper packaging material, polyethylene, polypropylene, polyvinyl chloride, polyester, oriented polypropylene and cellophane films were used to package sweet pepper and crisphead lettuce. The best result was obtained for sweet pepper in 0.03mm OPP film which showed shelf life of 41 days and weight loss 0.44% at low temperature. For crisphead lettuce it was obtained in PET film which showed shelf life of 40 days and weight loss 1.91% at low temperature. Shelf life of sweet pepper was extended up to 11 days at room temperature storage and 22 days at the low temperature storage. That of crisphead lettuce was extended up to 8 days at the room temperature storage and 37 days at the low temperature storage.

成分未詳의 漢藥服用後 發生한 Stevens-Johnson 症候群 1例

허성호,조보연,최규완,강석영 대한의학협회 1975 대한의학협회지 Vol.18 No.10

외과적 정출술을 통한 치은 하방 치경부 파절선이 있는 상악 전치부의 심미 보철 치료

이소진,김유진,박영범,조규성,정문규 大韓齒科補綴學會 2012 대한치과보철학회지 Vol.50 No.3

Surgical extrusion, immediate extrusion following tooth luxation, is a method to preserve one's natural tooth and achieve esthetic restoration without additional periodontal surgery when subgingival dental caries or crown fracture occurs. A 16-year-old male was referred to the clinic from the department of operative dentistry for the esthetic restoration of maxillary left lateral incisor. Due to the crown to root fracture, the tooth was endodontically treated with a buccal crown length of 4 mm. When the palatal flap was elevated, the mesiopalatal cervical fracture area was situated 3 - 4 mm subgingivally. Crown lengthening was achieved through surgical extrusion. After 3 months of clinical observation and provisional restoration, the maxillary left central incisor was restored with all ceramic crown and obtained a satisfactory clinical result. 치은연 하방에 치아 우식증이나 치아 파절이 발생했을 때, 치아를 탈구시켜 즉시 정출시키는 외과적 정출술을 이용한 치관 연장술은 자연치를 보존하고 추가적인 치주적 수술 없이 단기간에 심미적인 보철 치료를 가능하게 한다. 본 환자는 16세 남환으로 본원 보존과로부터 상악 좌측 중절치의 심미 수복을 위해 본원 보철과로 의뢰되었다. 상악 좌측 중절치는 근관치료가 되어 있었으며 치관-치근 파절로 인해 협측 치관 길이는 4 mm였으며 구개측 판막을 열었을 때 근심 구개측 치경부 파절 범위는 치은 하방 3 - 4 mm에 위치하였다. 외과적 정출술을 통한 치관연장술을 시행하였으며 경과 관찰 및 임시 치아의 단계를 거쳐 3개월 후에 전부 도재관으로 수복하여 만족할 만한 임상 결과를 얻을 수 있었다.

일 농촌지역의 우울 증상에 관한 역학연구 -위험요인 및 요인구조분석

하양숙,홍진표,김한규,이군희,한경자,조맹제,김용익,송미순,박성애,김창윤 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.2

연구목적 : 세계적으로 널리 사용되는 우울증 척도인 the Center for Epidemiologic Studies Depression Scale(CES-D)을 이용하여 지역사회 주민의 우울증상의 정도를 평가하고, 우울증상의 위험요인을 분석하고, 한국인에서 우울증상의 요인구조를 알기 위해 본 연구를 실시하였다. 방 법 : 경기도 일 농촌 지역의 30세 이상 주민에 대해 무작위 군집 집락 추출을 실시하였고, 훈련된 면담원들이 가정 방문을 통하여 면접 및 자기보고 검사인 CES-D를 실시하였다. 총 1,315명에서 응답을 하였고 응답율은 59.3%이었다. 결 과 : CES-D에 의한 우울증 점수는 0∼5점이 57%정도를 차지하였고, 평균 점수는 남자 7.8점 여자 9.5점으로 비교적 낮은 편이었다. ANCOVA 분석 결과 비결혼, 저학력, 여성이라는 위험요인은 독립적으로 우울증상을 악화시키는 요인이었으나 연령은 통계적으로 유의하지 않았다. CES-D 결과를 요인분석을 시행한 결과 4가지 요인이 추출되었는데 우울증상 및 신체증상이 한 개의 요인으로, 다른 나라에서 보고되지 않는 정서적 고통이 별도의 요인으로 추출되었다. 결 론 : 국내 역학 조사에서도 외국과 유사한 우울점수 및 위험요인이 확인되었으나 우울증의 요인에서는 특이한 요인이 추출되었다. 한국인에 독특한 우울 반응에 관한 추가 연구가 필요하다. Objectives :The rates, correlates, and factor structure of depressive symptoms in a Korean rural sample were examined using Korean version of the Center for Epidemiologic Studies Depression Scale(CES-D). Methods : Door to door visiting survey was conducted by trained interviewers. A random cluster sample of 1,315 respondents, aged 30 and over completed the CES-D scale along with additional sociodemographic questionnaire. Results : In this sample, mean CES-D score of male and female were 7.8 and 9.5, respectively which were lower than those reported previously. Symptoms of depression were most common among the less educated, non-married and female according to ANCOVA. Age was not a significant risk factor for depressive symptoms. Different factor structures emerged from this sample as compared to other studies using this approach. Somatic symptoms and affective symptoms were combined as one factor and emotional hardship emerged as a separate factor. Conclusion : Symptoms scores and risk factors were similar to the results reported in other countries but unique factor structures were found in this study. Further research is needed about the Korean depressive symptomatology and related areas.

Research Forum Oral Presentation : Bone formation by E.coli-expressed rHBMP-2 using MBCP block carrier in a rat calvarial defect and ectopic subcutaneous model

( Sung Soo So ),( Yoo Jung Um ),( Ui Won Jung ),( Chang Sung Kim ),( Seong Ho Choi ),( Jung Kiu Chai ),( Chong Kwan Kim ),( Kyoo Sung Cho ) 대한치주과학회 2009 대한치주과학회 학술대회자료집 Vol.2009 No.1