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USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance
Lee, Jin-Ku,Chang, Nakho,Yoon, Yeup,Yang, Heekyoung,Cho, Heejin,Kim, Eunhee,Shin, Yongjae,Kang, Wonyoung,Oh, Young Taek,Mun, Gyeong In,Joo, Kyeung Min,Nam, Do-Hyun,Lee, Jeongwu Oxford University Press 2016 Neuro-oncology Vol.18 No.1
<P>USP1-mediated protein stabilization promotes GSC maintenance and treatment resistance, thereby providing a rationale for USP1 inhibition as a potential therapeutic approach against GBM.</P>