고혈압 환자들의 건강행태

김석범,강복수,윤성호,황정희,이경수 韓國保健敎育.健康增進學會 2000 보건교육건강증진학회지 Vol.17 No.1

This study was conducted to examine health behaviors in hypertensive patients and the factors that would affect these healthy life-styles, and to provide basic data for effective and continuous hypertension control in private medical facilities. Among those patients diagnosed as hypertension who had visited the Department of Internal Medicine of Yeungnam University Hospital during the two month period from August 2 to September 30, 1999, the present study included 222 patients who were in more than one month after the initial diagnosis of hypertension and those who had hypertension for less than 10 years. Using a structured questionnaire, the present study was conducted by a self-administered survey method, and the obtained data were analyzed with t-test, χ2-test and one-way analysis of variance using the SPSS statistical program. The scores on knowledge related to hypertension were higher as the education level of a patient was higher(p〈0.05). As for occupation, those who performed office or management jobs showed higher scores than those who were into manufacturing jobs, and as for economic status, although those patients who were in middle class showed highest scores, however, no statistical significance was observed. The scores of knowledge on hypertension was higher when the family history hypertension was present(p〈0.05). The scores of health-related behaviors were higher with higher education level and higher economic status, higher in those with family history of hypertension, and higher in those with office or management jobs than those who had manufacturing jobs(p〈0.05). Blood pressure measurement on regular basis was performed most frequently in those who were between 50∼59 years old with 83.3% and was least frequent in those who were older than 70 years old with 50%(p〈0.05). The frequency of regular blood pressure measurement was higher with higher education level, higher economic status, higher in those with family history of hypertension, and the highest in those with management position with 93.5%, however, on statistical significance was observed. Changes in health-relaxed behaviors after hypertension diagnosis were higher with higher education level, higher economic status, and in those patients performed office or management work. In particular, diet change was observed in female and higher economic status and smoking cessation was observed in 60∼69 years old. Housewives and office workers or managers have taken exercise more regularly and those who had management jobs and had high scores on knowledge related to hypertension would participate health education program more actively. Thus, for improving health-related behaviors for continuous management of hypertension, changes in health-related behaviors can be followed through conduction health education to improve understanding of knowledge related to hypertension as the method of helping to improve changes in health life-styles in those with little education and those in low economic status.

광양만 묘도해역의 魚類 군집의 종조성 및 양적변동

한경호,윤연미,양한춘 여수대학교 1998 論文集 Vol.13 No.2

전라남도 광양만 묘도 주변의 연안어장에서 1997년 2월부터 12월까지 6회에 걸쳐 소형 저인망을 이용하여 어획물을 채집하여 魚類 군집의 종조성 및 양적변동을 조사하였다. 채집된 어류는 총 8目 38科 56屬 66種 21,541개체, 175,330g 으로 농어目(Perciformes), 쏨뱅이目(Scorpaeniformes) 및 가자미목(Pleuronectiformes) 어류가 총 50種으로 전체 출현종수의 75.8%를 차지하였으며, 科別로는 망둑어科() 어류가 8種 出現하여 가장 많았다. 총 66種의 어류중 개체수는 주둥치(Leiognathus ruchalis), 전어(Konosirus punctatus), 멸치(Engraulis japonicus), 준치(Ilisha elongata), 실양태(Repomucenus valencinnei), 보구치(Argyrosomus argentatus), 및 청멸(Thryssa kammalensis)의 7種이 전 개체수의 95.4%를 차지하여 우점종으로 나타났다. 生體量은주둥치, 전어, 꼼치(Liparis tanakai), 숭어(Mugil cephalus), 준치, 보구치, 문절망둑(Acanthogobius flavimanus), 멸치, 쥐노래미(Hexagrammos otakii) 및 실양태의 順으로 이들 10種이 全生體量의 86.1%를 차지하여 우점하였다. 출현 개체수와 생체량은 고수온기인 봄과 여름에 높게 나타났으며, 저수온기의 가을과 겨울에 낮게 나타나 수온과 밀접한 관계가 있었다. 월별 출현종수는 수온이 낮은 2월과 높은 8월에 각 19種과 20種이 出現하여 적었고, 수온이 상승하기 시작한 4월에 37種으로 가장 많았다. 종다양도지수는 0.460∼1.833으로 2월에 가장 높았으며, 6월에 낮았다. 주요 魚種의 出現頻度는 주둥치, 전어, 준치 및 실양태가 年中 出現하여 본 해역에 우점하는 주거종으로 나타났다. To determine seasonal fluctuations in abundance and species composition, fish samples were collected by a bottom trawl from February to December 1997 off Myo-do in Kwangyang Bay. A total of 21,541 fishes were sampled and indentified into 66 species, 38 families and 8 orders. Of the eight orders, Perciformes, Scorpaniformes and Pleuronectiformes accounted for approximately 75.8% of the fish fauna in this area. Gobiidae was dominant representing 8 species. Of 66 species identified, Leiognathus nuchalis, Konosirus punctatus, Engraulis japonicus, Ilisha elongata, Repomucenus valenciennei, Argyrosomus argentatus and Thryssa kammalensis accounted for 95.4% of the individuals collected. Leiognathus nuchalis, Konosirus punctatus, Liparis tanakai, Mugil cephalus, Ilisha elongata, Argyrosomus argentus, Acanthogobius flavimanus, Engraulis japonicus, Hexagramus otakii and Repomucenus valenciennei constituted 88.1% of the total biomass. Fish fauna in both number and biomass were higher in spring and summer, than other in autumn and winter. A peak abundance of total fishes occurred in April: the following abundance July: the lowest abundance in February. The number of species showed some significant seasonal variations however, a larger number of individuals and greater biomass was observed from July to August than October to the next February.

뇌졸중 위험인자를 가진 어지럼 환자에서의 확산강조 자기공명영상

강형구,윤유상,이진희,박인철,이경룡,정상원,구홍두,김승호 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: The management of vertiginous patients is a great challenge to emergency physicians. We evaluated the diagnostic value of a diffusion-weighted image(DWI) in differentiating central vertigo from the peripheral vertigo in patients who presented no neurological symptoms other than risk factors for stroke. Methods: From March 2000 to February 2001, we retrospectively analyzed the cases of 68 patients who visited the emergency department with symptoms of isolated vertigo and who had risk factors for stroke. DWIs, computed tomograms(CT), and medical records were reviewed, and the final diagnose, the DWIs and the CT readings, the risk factors for stroke, and the time it took waiting for a DWI or CT scan were analyzed. Results: Of the 68 patients, 21(30.8%) had central vertigo: 15 vertebrobasilar transient ischemic attacks(VB-TIA), 4 brain stem infarctions, 1 cerebellar infarction, and 1 cerebellopeduncular infarction. The DWI showed a 28.6% sensitivity, a 97.9% specificity, and an 85.7% positive predictive value in diagnosing central vertigo. It also had a 100% sensitivity in detecting infarctions. Conclusion: A DWI had a comparable sensitivity to MRI in detecting central vertigo and small, but potentially, lethal infarctions in our patient population. We recommend clinical application of DWI in the emergency department evaluation of isolated vertigo patients with risk factors for stroke.

석청(Mad-honey) 복용 후 유발된 부정맥 1예

김용철,김남호,김승환,최준호,박은미,이상재,이은미,유남진,윤경호,오석규,정진원 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

석청에 포함된 grayanotoxin에 의해 독성 작용이 나올 수 있으며, 이러한 독성 작용은 일반적으로 24시간 이내 저절로 회복된다. 최근에 본 저자들은 석청 복용 후 발생한 심실빈맥을 경험하였기에 보고하는 바이다. 49세 남자가 호흡곤란으로 내원하였으며, 내원당시 분당 40회 정도의 동성 서맥이 관찰되었고, 수액을 투여하던 중 심실 빈맥이 발생하였다. 항부정맥제를 투여 후 정상 동율동으로 전환되었으며, 특별한 이상 없이 4일 후 퇴원하였다. Mad-honey intoxication caused by the consumption of honey producted from the nectar of rhododendrons. The grayanotoxins cause the intoxication. The toxic effects of mad-honey poisoning are rarely fatal and generally last for no more than 24 hours. We experienced one case, a 49 years-old man who presented with dyspnea after ingestion of mad-honey. He showed marked sinus bradycardia with < 40 beats per minute on admission. The cardiac rhythm was changed to ventricular tachycardia immediately. These features resolved completely in 24 hours with continuous infusion of amiodarone(600 mg per day) and fluids. We report the case of intoxication of mad-honey as a presentation of fatal cardiac arrhythmia.

Long-term outcomes of simple crossover stenting from the left main to the left anterior descending coronary artery

( Ho Myung Lee ),( Chang Wook Nam ),( Yun Kyeong Cho ),( Hyuck Jun Yoon ),( Hyoung Seob Park ),( Hyung Seop Kim ),( In Sung Chung ),( Yun Seok Heo ),( Seung Ho Hur ),( Yoon Nyun Kim ),( Kwon Bae Kim ) 대한내과학회 2014 The Korean Journal of Internal Medicine Vol.29 No.5

Background/Aims: Although complex bifurcation stenting in patients with nonleftmain (LM) bifurcation lesions has not yielded better clinical outcomes thansimpler procedures, the utility of complex bifurcation stenting to treat LM bifurcationlesions has not yet been adequately explored. Methods: In the present study, patients who underwent LM-to-left anterior descending(LAD) coronary artery simple crossover stenting to treat significantde novo distal LM or ostial LAD disease, in the absence of angiographically significantostial left circumflex (LCX) coronary artery disease, were consecutivelyenrolled. The frequencies of 3-year major adverse cardiovascular events (MACEs;cardiac death, myocardial infarction, and target lesion revascularization), wereanalyzed. Results: Of 105 eligible consecutive patients, only 12 (11.4%) required additionalprocedures to treat ostial LCX disease after main vessel stenting. The mean percentagediameter of ostial LCX stenosis increased from 22.5% ± 15.2% to 32.3% ±16.3% (p < 0.001) after LM-to-LAD simple crossover stenting. The 3-year incidenceof MACEs was 9.7% (cardiac death 2.2%; myocardial infarction 2.2%; target lesionrevascularization 8.6%), and that of stent thrombosis 1.1%. Of seven cases (7.5%)requiring restenosis, pure ostial LCX-related repeat revascularization was requiredby only two. Conclusions: Simple crossover LM-to-LAD stenting without opening of a struton the LCX ostium was associated with acceptable long-term clinical outcomes.

Quantitative Analysis Method for Harmful Carbonyl Compounds in E-cigarette Liquid Using Gas Chromatography-Mass Spectrometry

Kyeong-Yun Choi,Yun-Suk Oh,Heesoo Pyo,Ho-Sang Shin 한국분석과학회 2023 학술대회논문집 Vol.2023 No.11

Development of Quantitative Analysis Method for Hazardous Residual Solvents in E-cigarette Liquid Using Headspace-Gas Chromatography-Mass Spectrometry

Kyeong-Yun Choi,Vu Thi Hoang Van,Yun-Suk Oh,Heesoo Pyo,Ho-Sang Shin 한국분석과학회 2023 학술대회논문집 Vol.2023 No.11

Clinical Significance of On-Treatment Triglyceride Level in Patients Treated by Percutaneous Coronary Intervention for Non-ST-Segment Elevation Acute Coronary Syndrome

( Kyeong Ho Yun ),( Ik Sang Shin ),( Sang Jae Rhee ),( Eun Mi Lee ),( Nam Jin Yoo ),( Nam Ho Kim ),( Seok Kyu Oh ),( Jin Won Jeong ) 대한내과학회 2009 The Korean Journal of Internal Medicine Vol.24 No.4

Background/Aims: The use of statins in patients with acute coronary syndrome (ACS) has increased, and reduced levels of low-density lipoprotein cholesterol (LDL-C) lead to lower coronary event rates. We studied the effect of lipid levels during statin treatment on prognosis in patients with ACS and percutaneous coronary intervention (PCI). Methods: Between January 2005 and May 2007, 325 ACS patients who underwent PCI and received statins were evaluated. We measured serum lipid levels at baseline and 4 weeks. The relationships between on-treatment levels of triglyceride (TG) and LDL-C and one-year major adverse cardiac events (MACE) were assessed. Results: At 4 weeks, the mean LDL-C level was 72.5±23.8 mg/dL and the mean TG was 123.2±62.8 mg/dL. MACE occurred in 41 cases (12.6%). Baseline serum lipid levels were similar between the patients with and those without MACE. However, the patients with MACE showed significantly higher TG level at 4 weeks (149.6±81.4 vs. 119.3±58.9 mg/dL, p=0.026) than those without. High on-treatment TG level (≥150 mg/dL) were associated with increased adverse events compared to lower TG level in a univariate analysis (hazard ratio [HR], 3.3; p<0.001). In a multivariate analysis, high 4-week TG level after statin treatment was an independent predictor for MACE (HR, 4.01; 95% confidence interval, 1.85 to 9.06; p=0.001), however, baseline TG and LDL-C levels were not. Conclusions: High on-treatment TG level (≥150 mg/dL) was associated with a higher risk of MACE. This finding supports the concept that achieving low TG levels may be an important therapeutic parameter in statin-treated patients following ACS and PCI. (Korean J Intern Med 2009;24:330-336)

Temporal Variability of Platelet Reactivity in Patients Treated with Clopidogrel or Ticagrelor

Kyeong Ho Yun,Sang Jae Rhee,Jae Young Cho,Seok Kyu Oh 대한심장학회 2019 Korean Circulation Journal Vol.49 No.11

Background and Objectives: The degree of antiplatelet response to P2Y12 inhibitors has been associated with clinical outcomes. The aim of this study was to test the variability of platelet reactivity over time among patients treated with clopidogrel or ticagrelor. Methods: A single-center cohort of acute coronary syndrome patients that underwent percutaneous coronary intervention (PCI) was analyzed. Platelet reactivity was measured at baseline, 48 hours after PCI, 1 month, and 6 months after clopidogrel (n=79) or ticagrelor (n=93) treatment. High on-treatment platelet reactivity (HPR) was defined as ≥47 U, assessed by multiple electrode platelet aggregometry. Results: Platelet reactivity in the clopidogrel group increased over time, 38.2±21.7 U at 48 hours, 41.4±22.3 U at 1 month, and 44.7±25.5 U at 6 months (p=0.018, 48 hours to 6 months). However, platelet reactivity in the ticagrelor group was not significantly changed, 21.4±12.6 U at 48 hours, 20.0±12.2 U at 1 month, and 22.8±13.8 U at 6 months (p=0.392). A platelet reactivity change over time of more than 20U was found in 67.1% of the patients with clopidogrel group and 34.4% of ticagrelor group (p<0.001). Between 48 hours and 6 months, 43% of patients changed their responder status in the clopidogrel group, and 13% in the ticagrelor group (p<0.001). Conclusions: Although ticagrelor treatment resulted in less temporal variability of platelet reactivity than clopidogrel treatment in terms of HPR, platelet reactivity varied over time in a significant proportion of patients.

An Increased Monocyte Count Predicts Coronary Artery Spasm in Patients with Resting Chest Pain and Insignificant Coronary Artery Stenosis

Kyeong Ho Yun,Seok Kyu Oh,Eun Mi Park,Hyun Jung Kim,Sung Hee Shin,Eun Mi Lee,Sang Jae Rhee,Nam Jin Yoo,Nam Ho Kim,Jin Won Jeong,Myung Ho Jeong 대한내과학회 2006 The Korean Journal of Internal Medicine Vol.21 No.2

Background: Coronary atherosclerosis with inflammation gives rise to coronary vasospasm in the patients with coronary vasospastic angina. We have postulated that the peripheral leukocyte count and the differential count are associated with vasospastic angi