40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

성인의 급성 설사에 대한 로페라미드 옥사이드의 효과: 위약과의 무작위 이중 맹검 비교 다시설 시험

박영태,정희진,박중원,이계희,김나영,임선희,윤병철,한동수,이오영 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.31 No.5

톡소포자충 배양시 약제투여에 따른 Toxoplasma P30 유전자의 발현

이상걸,이영하,김계영,나영언,신대환 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

To know the drugs effect on gene expression and its regulating mechanism by RT-PCR and southern blot hybridization assay based on detection of the P30 gene encoding the major surface antigen, P30 of Toxoplasma gondii and the DNA synthesis in T. gondii infected HeLa cells. The experiment was performed and the results were as follows. 1. The thymidine incooperation in DNA of HeLa cell and T. gondii infected HeLa cell reached peak level at 36 hours and suddenly decreased at 48 hours. The uracil incooperation in DNA of T. gondii reached peak level at 48 hours. 2. The decrease of P30 gene expression began from 24 hours after pyrimethamine treated and 36 hours after methotrexate treated in T. gondii. The results were some what different. Pyrimethamine was more sensitive and acted earlier to T. gondii than Methotrexate did. The decrease of P30 gene expression of T. gondii was regulated these drugs in dose dependent manner. 3. The effects of dibutyryl cyclic AMP on P30 gene expression increased peak at 24 hours and on contrary decreased at 60 hours after treatment in dose dependent manner, but at 10mM high concentration of dibutyryl cAMP, P30 gene expression was supressed. 4. Actinomycine D supressed the P30 gene expression of T. gondii in HeLa cell. As the results, we presume pyrimethamine acts more powerful and earlier to supresses P30 gene expression than methotrexate, and it is regulated at transcription level. The results of RT-PCR were in agreement with that of southern blot hybridization.

일 도농복합지역 저소득층 노인의 건강문제 분석 : 보건소 방문간호사업 대상자 중심으로

고일선,,이태화,이경자,이정렬,임미혜,천의영,주윤미,이계철 노인간호학회 2005 노인간호학회지 Vol.7 No.2

Purpose: The purpose of this study was to analyze the health problems of low-income aged with chronic illness living in urban-rural composite area. Method: The sample consisted of 440 aged who were receiving home care services from a public health center. MDS-HC was applied to analyze the health problems of the aged. Data were collected through a face- to-face interview by six trained interviewers from June 28 to July 15, 2004. Result: Subjects had average number of 8 health problems in both urban and rural area. Lack of preventive health care measure, pain, and visual function were the most frequent health problem. The rural aged had more pain, bowel management problems, compared to the urban aged having more urinary incontinence and indwelling catheter. There were many health problems related to falls and pressure ulcers with middle-old aged in urban, and old-old aged in rural area. Conclusion: The results of this study showed strategies for care intervention of low-income elderly to put in practice. Therefore, tailored-service for each subject should be provided.

조직확장술및 장골이식을 이용한 하악골 결손부의 재건

이계영,민경인,정수일,박재범,안재진,김도균,김철환 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.4

Soft tissue expansion is widely used technique in oral & maxillofacial reconstruction and provide new method of reconstruction in posttraumatic alopecia, post burn, wide scar, congenital deformity, benign tumor, tattoo, etc. Expanded tissue flaps have the advantage of increased vascularity, proximity to the defect, and similarity of color and texture. They also preclude the need to advance flaps from distant sites. Tissue expansion can be used to form a well vascularized cavity to accomodate and nourish bone grafts. The following report describes the uses of tissue expanders by allowing bone grafting to correct both soft and bony defects of mandibular region

냉수 가글링과 젖은 거즈를 이용한 구강간호가 비강수술 환자의 갈증 및 구강상태에 미치는 효과 비교

이인선,심명숙,나은희,강재연,김지혜,황민영,윤계숙,성영희 병원간호사회 2006 임상간호연구 Vol.11 No.2

Purpose: This study researched the comparison of oral care methods between the wet gauze and the water gargling for nasal surgery patients. It executed to find out more effective method to relieve thirst. Method: We divided two groups; the wet gauze and the cold water garaling. We assessed patient's oral cavity state and sebjective oral dryness for three times; firstly before the intervention, secondly 15 minutes after 1st intervention and thirdly 15 minutes afrer 2nd intervention. Result: As the intervention, there was no difference on oral condition subhectvely, but there was a difference on thirsty reduction objectively. As the aral dryness has relieved through both methods. It showed the repeated gargling helps more to relieve oral dryness effectively than the wet gauge. At PACU, post nasal surgery patient's oral dryness was decreased with gauze more than two times, patient's oral dryness was relieved. Whereas the dryness was relieved after applying the cold water gargling for just one time. Conclusion: The water gargling is more effective intervention than the wet gauze. Especially, oral dryness was improved in the section of objetive oral assessment index.

HL-60 세포 분화유도증 c-Myc 발현에 대한 세포분화유도제의 영향

이용진,곽상태,김계영,이명선,권기량,임규,황병두 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Effects of the differentiation inducers on DNA synthesis and c-myc gene expression have been investigated during the differentiation of human promyelocytic leukemia cell line HL-60. All-trans retinoic acid(retinoic acid) and dimethyl sulfoxide(DMSO) decreased DNA synthesis at 24 hours and 12-O-tetradecanoylphorbol 13-acetate(TPA) decreased at 12 hours after exposure, respectively. On the other hand control, no adding differentiation inducers, gradually increased DNA synthesis. The c-myc mRNA was sharply reduced at 24 hours in retinoic acid-, at 4 hours in DMSO-, and at 1 hour in TPA-exposured HL- 60 cells. The level of c-myc mRNAs was reduced in proportion to the concentration in all of three differentiation inducers. The level of c-myc mRNAs in the differentiation inducers-exposured cells were elevated by cycloheximide treatment. These results suggest that c-myc gene expression and differentiation mechanism are variable according to the kinds of the differentiation inducers in HL-60 cells.

공업계고등학교 '공작기계 Ⅰ' CAD수업에서 JigsawⅡ 협동학습이 학업성취도에 미치는 효과

이세계,이상봉,금영충 한국직업능력개발원 2004 직업능력개발연구 Vol.7 No.1

이 연구는 공업계고등학교 '공작기계 Ⅰ' CAD수업에서 JigsawⅡ 협동학습이 학생들의 학업성취도에 미치는 효과를 알아보는 데 그 목적이 있다. 실험은 '정적집단 비교 설계' 를 실험 모형으로 적용하여 실험 집단은 JigsawⅡ 협동학습 집단으로, 통제 집단은 전통적 수업방법을 시행하는 집단으로 구성하였다. 실험결과를 통해 CAD수업에서 JigsawⅡ 협동학습은 학업성취도를 향상하는 데 전통적 수업방법보다 효과가 없는 것으로 나타났다. 그 원인은 이 연구의 CAD수업 내용이 기초적인 내용이었고, 또 대상 학생들이 공업계고등학교에 입학한 1학년 학생들로 CAD수업에 대한 내용을 처음으로 공부하게 되어 수업 내용에 대한 이해가 충실하지 못했기 때문인 것으로 판단된다. 따라서 학생들이 처음으로 접하게 되는 수업내용이나 기초적인 수업 내용에 대한 JigsawⅡ 협동학습 관련연구를 시행하고자 할 때에는 수업에 대한 준비가 더 필요할 것으로 판단된다. 특히 공업계고등학교에서는 학생들의 기본 학습 능력의 부족, 학업에 대한 흥미 저하, 재학생의 중도탈락증가 등의 여러 가지 문제들이 나타나고 있는데, 학교 현장에 종사하는 교사들은 이러한 문제를 해결하기 위해서 학생들이 학업에 흥미를 갖도록 다양한 교수학습 방법을 구안 후 적용해야 할 것이다. The purpose of this study was to verify the effects of JigsawⅡ cooperative learning on academic achievement of Computer Aided Design(CAD) instruction, the Machine Tool Ⅰsubject of technical high school. To verify the hypotheses of this study, 2 parts(16 students in each part) of the first grades from technical high school in Cheong-Ju were selected. Each part was divided into three sub-groups by the level of entering behavior levels. Static-Group Comparison Design was applied for experimental planning. The content of the experiment was the CAD instruction in the Machine Tool Ⅰ textbook. The experimental group was taught using a JigsawⅡ cooperative learning method and the control group using a traditional teaching method. The independent variable was teaching method and the dependent variable was academic achievement. The data was analysed using a t-test with a significance level of 0.05 Significance level established prior to data treatment. The result of this study were as follows; First, the JigsawⅡ cooperative learning in CAD instruction had little effect on the academic achievement Second, the JigsawⅡ cooperative learning in CAD instruction had little effect on the academic achievement in the entering behavior levels. Finally, the JigsawⅡ cooperative learning in CAD instruction had little effect on the academic achievement in the cognitive and functional domain of the brain.

유두에 발생한 음부 평활근종 1예

계경채,이영,서영준,이증훈,박장규,김진만,김협 대한피부과학회 2006 大韓皮膚科學會誌 Vol.44 No.4

아음속풍동의 제작과 난류경계층 구조의 변화에 관한 연구

李南榮,朴桂香,柳相信 한국항공대학교 1991 論文集 Vol.29 No.-

본 연구에서는 풍동의 활용성과 경제성, 장비설치 및 취급의 용이성등을 고려하여 요구풍속을 결정한 후 확산부, 정체실, 수축부, 시험부등을 설계하고, 제작된 풍동에 대한 성능검사를 실시하였다. 정체부와 시험부 수축비는 9이고 시험부의 단면은 406mm×406mm 이며 길이는 1,200mm 이다. 시험부에서 얻을 수 있는 최대속도는 송풍기 회전수 1,500rpm 일때 36m/sec이다. 송풍기 동력은 19kW 이며 송풍기 형태는 원심형 임펠러를 선택하였다. 시험부의 성능을 검사하기 위해 열선유속계를 사용하여 시험부 출구 단면에서의 속도분포와 난류강도를 조사하였다. 시험부의 속도는 5m/sec 에서 30m/sec 까지의 범위에서 난류강도는 0.5%이고 벽면경계층 두께를 고려하면 유효 단면적은 약 85%이다. 제작된 풍동에 에머리 페이퍼(emery paper) 또는 트리핑 와이어(tripping wire)를 부착한 매끈한 평판과 축대칭 3차원 물체를 장치하여 경계층 속의 흐름이 난류가 되도록 하였고 발생된 난류 경계층의 특성을 분석 하였다. In the present experimental study, the range of wind speed at the test section was determined by considering the availability, economy, installation and handling of the wind tunnel, and diffuser section, settling chamber, contraction section and test section of the wind tunnel were designed and manufactured to satisfy the prescribed wind speed range. Performance of the manufactured wind tunnel was tested according to the normal testing procedure. Contraction ratio of the test section to the settling chamber is 9 and the cross section of the test section is 406mm×406mm and the test section is 1200mm long. The maximum air speed at the test section is 36m/sec for the motor speed of 1500 rpm. A centrifugal type fan is used and the maximum power required is 19kw. The hot-wire anemometer system was employed to test the performance of the wind tunnel by measuring the velocity distribution and turbulent intensity at the exit of the test section. Measured values of turbulent intensity were less than 0.5% for the range of wind speed from 5m/sec to 30m/sec. The available cross sectional area of the test section was about 85%. Flat plate and axisymmetric three dimensional body were used as models to identify the boundary layer characteristics. The boundary layers were triggered by emery paper and/or tripping wire. The characteristics of the generated turbulent boundary layers were analyzed.