주산기 백서에서 혈중 에스트로겐 농도와 공간 기억력과의 상관관계

박민성,박제민,신성현,한귀원,김명정,김성곤 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.5

Objectives : This study was designed to find possible effect of pregnancy and parturition on spatial memory, especially in relation to levels of estrogen during the third trimester and postpartal period in rats. Methods : 25 female Sprague Dawley rats were divided into pregnant group (N= 14) and control group (N= 11). Changes in spatial memory during 6 weeks including third trimester and postpartal period were measured using Morris water maze. Time to reach the platform in the maze was indicator of spatial memory. Serum estrogen level was measured on 1 week before delivery, postpartal day 1, and day 14. Results : Both groups showed gradual improvement in performance by trial days and weeks, but no significant difference was found between the two groups. However in the third trimester, pregnant group showed a trend of less achievement on 3 days of learning than control group. Serum estrogen levels did not differ significantly between groups over the 6 weeks of period. However there was positive correlation between serum estrogen level on postpartum day 1 and time to reach platform on postpartum week 2, and negative correlation between estrogen level on postpartum day 14 and latency to the platform on postpartum week 5. Conclusion : These results imply that changes in the serum estrogen level may have dual effects on the spatial learning in peripartal period. It is suggested that decline in cognitive function might occur either by failure of rapid decrease of estrogen, immediately after parturition, or retarded restoration of estrogen in later postpartal period.

대전지역 대학생들에 의한 대학 급식소의 급식평가

박상욱,하귀현 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.5

대전지역 대학생들에 의한 대학급식소의 급식평가를 조사하기 위하여 3개 대학의 남녀 대학생 309명에게 설문 조사한 결과를 요약하면 다음과 같다. 1. 학생들이 대학급식소를 평가한 것 중 음식 및 메뉴의 특성에 대해서는 음식의 양, 영양가는 대체로 적절하다고 평가되었으나 온도, 신선도, 계절음식의 이용성, 식단의 변화, 메뉴선의 다양성은 만족하지 못하고 있는 것으로 나타났으며, 학교별로는 B학교가 맛, 외관, 영양가, 신선도, 식단의 변화, 가격 등에서 낮은 점수평가를 하여 불만족한 것으로 나타났다. 2. 위생 및 종업원의 태도에 대한 평가에서는 전체적으로 종업원의 위생, 배식시 신속함, 용모의 단정함, 친절함은 보통으로 평가되었으나 음식의 위생, 식기의 청결은 만족하지 못한 것으로 평가되었으며 A, B학교는 음식의 위생에서 낮게 평가되었고 B학교는 식기의 청결에서 낮게 평가되었다. 3. 식당시설에 대한 평가에서는 전체적으로 식탁 및 의자배치, 반납구의 위치, 카운터의 위치, 메뉴판 사용, 환기시설 등은 보통 정도라고 평가하였으나 실내장식, 난방시설은 낮은 평가점수를 나타내었다. 학교별로는 A학교는 식탁 및 의자배치, 카운터의위치, 난방시설, 실내장식 등에서 낮은 점수를 보여 불만족한 것으로 나타났으며 B학교는 메뉴판사용에서 평가 점수가 낮았다. 4. 식당분위기 및 편리성에 대한 평가에서는 전체적으로 조용함, 편안함에서 불만족하게 나타났고, 식당의 위치, 식당 운영시간, 줄서는 시간은 적절하다고 평가되었으며, 휴식공간은 평가점수가 낮았다. 학교별로는 A학교가 줄서는 시간, 휴식공간에서 낮은 평가점수를 나타내 개선해야 할 것으로 생각되며 C학교는 줄서는 시간에서 낮은 평가점수를 나타냈다. 줄서는 시간이 길어 학생들에게 불편함을 주는 요인은 배식시간의 짧음, 식권의 제한 판매, 카운터의 위치, 강의시간표의 영향 등이 관계하고 있었다. 전체적으로 볼 때 음식의 온도와 신선도, 계절음식의 이용성, 식단의 변화, 메뉴선택의 다양성, 음식의 위생, 식기의 청결, 실내장식, 난방시설, 휴식공간 등은 낮은 평가점수를 나타내 대학급식에서 만족하지 못하고 있음을 알 수 있다. 이상의 결과를 살펴볼 때 대전지역 대학급식소에 대한 학생들의 급식평가는 전반적으로 만족하지 못하고 있는 것으로 나타났다. 이는 앞으로 더욱더 급식의 품질향상을 위해 노력해 나가야 할 것으로 보며 이를 위해서는 음식의 맛, 위생, 식단의 다양화, 급식시설 등에 더욱 개선을 하여 보다 나은 급식을 제공할 수 있어야 하고, 또한 급식 대상자들이 만족한 급식을 할 수 있도록 급식관리자들은 적극적이고 다양한 급식평가를 통해 문제점을 재검토하여 보다 효과적인 급식운영을 해야 할 것으로 사료된다. This study was conducted to provide some basic information for promoting efficiency in university food services. Subjects were 309 students of A,B and C university. The survey was done by questionaires, and the data were analyzed by SAS program. The quantity and nutritional value of food was evaluated as appropriate but temperature and freshness of food, use of seasonal food, variety of menu were indicated as unsatisfactory. Male students marked lower points on the price but female students gave lower scores for variety of menu and use of seasonl food. Employee hygiene fast service and neatness and kindness of workers were evaluated as appropriate but food sanitation and cleanness of dishes were indicated as unsatisfactory. A and B university students scored low marks on food sanitation. Female students scored higher marks on the employee's neatness. Arrangement of tables and chairs, location of returning utensils, location of counter use of menu board and ventilation facilities were scored as average but interior decoration and heating facilities were scored as low level. Students of a school scored low mark on the arrangement of tables, location of counter, heating facilities and interior decoration but students of B school scored low mark on the use of menu board. Calmness and comfortableness of dining hall was unsatisfactory but location of dining hall, serving time and waiting time were evaluated as appropriate. In conclusion improvements for temperature and freshness of food, use of seasonal food, variety of menu, food sanitation, cleanness of dishes, interior decoration, heating facility and resting area were indicated as necessary.

평면 가까이에서 부상하는 기구의 제어특성에 관한 연구

박선국,이상관,최부귀 동아대학교 공과대학 부설 한국자원개발연구소 1990 硏究報告 Vol.14 No.2

A multi-fan hovering mechanism is investigated as a vehicle for field work at a mountainous resion. This paper presents its control characteristics in level ground proximity. The motion is formulated considering ground effect. A controller stable for the change of property with height is presented The experimental results obtained using a scale model are presented. It is shown that the controller works properly, problems are made clear to improve the hovering charactistics.

위치제어계에서 외란관측기 설계에 관한 연구

박선국,이상관,최부귀,하홍곤 동아대학교 공과대학 부설 한국자원개발연구소 1991 硏究報告 Vol.15 No.1

The dynamics of the Multi―degree of freedom manipulator is highly nonlinear and the compensation against this nonlinearity should be indispensable. This paper proposes the decentralized joint control method based on the distrubance observer where the dynamical equation is not directly solved. This system has excellent performance of disturbance supression, because the total acceleration including the load torque and various kinds of frictional torques can be controlled directly, come experiments show the effectiveness of the proposed system. This paper discuss the important relationships with the feedforward compensation type Servo system using distrubance torque observer.

직접극배치 PID 자기동조 알고리즘을 이용한 제어기 설계에 관한 연구

김성대,박선국,최부귀 동아대학교 공과대학 부설 한국자원개발연구소 1990 硏究報告 Vol.14 No.2

One of the advantage of the well-known PID controller is that it is a sufficients flexible controller for many applications. But, when the flant paramaters and distrubance are unknown or change with time, it is desirable to make automatic tuning of PID controller in order to achive an acceptable level of performance of the control system. In this paper, classical controller parameters are estimated by the recursive least square(RLS) identification algorithm, the pole placement method and Diopantine euqation. A series of simulations in which stationary stage and state with distrubance are subjected to a patten of system parameter changes is presented to show some of the features of the proposed control algorithm.

신경회로망을 이용한 시변 동적 시스템의 적응제어

이상관,박영식,최부귀 東亞大學校 附設 情報通信硏究所 1995 情報通信硏究所論文誌 Vol.3 No.1

본 논문에서는 시변 동적 시스템의 적응제어를 위한 신경회로망의 응용에 대해 제안한다.플랜트를 제어하기 위하여 역동적 신경회로망 모델을 사용하는 학습이 필요하다. 제안된 시스템은 제어회로망과 학습회로망으로 구성된다. 제어회로망은 제어된 플랜트와 직렬로 구성한다. 학습회로망은 회로망이 동작하는 동안 역 동적 학습을 하기 위해 플랜트와 병렬로 구성한다. 제어회로망은 궤환오차와 원하는 플랜트의 출력을 입력으로 하여 제어 신호을 발생한다. 시뮬레이션 결과를 통해서 본 연구에 제안된 적응 추적제어 문제의 응용 가능성을 확인한다. In this paper an application of neural networks to the adaptive control of time-varying dynamic systems is proposed. The essence of the approach adopted was to use a neural network model of the inverse dynamics of a plant to control that plant. The proposed control system comprises a control network and a training network. The control network is placed in series with the controlled plant. The training network is positioned across the plant to learn its inverse dynamics during operation. The control network generates control signals to the plant, taking as its inputs the desired plant output and the feedback error. Simulation results are presented to illustrate the applicability of the proposed scheme to adaptive tracking control problems.

연시첨가가 김치의 발효와 기호성에 미치는 영향

하귀현,박상욱 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.5

연시를 배추김치에 0, 5, 10, 15% 첨가하여 4℃에서 20일간 저장하면서 pH, 산도, 염도, 환원당, Vit.C 및 관능적 특성을 분석하였다. pH는 저장기간에 따라 점차 낮아지고 시료간에는 거의 차이가 없었다. 산도는 숙성초기 pH의 변화가 급격히 낮아질 때는 균일하고 숙성후기에 점차 증가하였으며 제조당일부터는 20일 동안 0.3∼1.0%를 나타내었다. 염도는 1.2∼2.2%로 숙성이 진행됨에 따라 점차적으로 감소하였으며 대조군이 전반적으로 염도가 높았다. 환원당은 저장 2일째 함량의 감소를 보였다. 발효진행에 따라 점차 감소하였고 연시 첨가군의 함량이 대조군보다 전반적으로 높았다. Vit. C는 저장 4일경 가장 높은 함량을 보였고, 이후 점차적으로 감소하였으며 연시 첨가군이 대조군보다 함량이 높았다. 관능검사 결과는 저장기간동안 맛, 향기, 텍스처 및 전반적인 바람직성에서 연시 10% 첨가군이 기호도가 가장 높게 나타났다. 따라서 김치에 연시를 첨가하면 김치가 숙성됨에 따라 연시가 김치의 기호성에 중요한 역할을 할 수 있는 것으로 볼 수 있다. This paper presents an investigation of chemical and sensory properties of Kimchi with red-ripe persimmon. Kimchi with different levels(0, 5, 10, 15%) of red-ripe persimmon was fermented at 4℃ for 20days. During the fermentation, pH decreased in all Kimchi samples and pH of Kimchi with red-ripe persimmon was a little lower than that of Kimchi without red-ripe persimmon. Acidity increased continuously and saltiness was maintained at 1.2∼2.2% levels during fermentation. The reducing sugar of Kimchi with red-ripe persimmon was relatively higher than that of the other sample without red-ripe persimmon. Total vitamin C(Vit. C) in Kimchi added red-ripe persimmon increased in the early stage of fermentation and reduced gradually after 4days of fermentation. In the sensory evolution, Kimchi with 10% red-ripe persimmon recorded high scores in taste, flavor, texture and overall acceptability during all fermentation period.

트라이애슬러의 비타민Q 섭취가 호흡순환기능 및 항산화 효소활성에 미치는 영향

현송자,김귀백,박상일,석혜경 東亞大學校附設스포츠科學硏究所 2002 스포츠科學硏究論文集 Vol.20 No.-

The purpose of this present study was to investigate the effect of VitaminQ supplementation on antioxidant enzyme activities and cardiorespiratory function following prolonged exercise in trained triathlers. Male 14 healthy college students of trained triathlers participated in exercise sessions. The subjects were divided into 2 groups, as Non-supplement(NS) or VitaminQ supplement(VQ) groups. VitaminQ subjects were participated in two exercise sessions: an initial prolonged exercise(swim 750m, running 10㎞) and 70%V O2max treadmill running exercise. The Non-supplement group fed normal diet. VitaminQ group adminstated 90㎎/day for 4weeks. Venous blood samples were drown from the forearm antecubital vein pre-supplement, pre-exercise and immediately post-exercise. The results of this study can be summarized as follow: First, the SOD activity of RBC was not changed, while the GPx, GR or GR/GPx activies of Hb were significantly increased following prolonged exercise with CoQ10 supplementation. Second, 70%VO2max treadmill running exercise increased significantly the V O2max and VE, but the heart rate significantly decreased. In conclusion, the present results clearly show that the VitaminQ supplementation gave rise to increase the GPx or GR activies and to improve the cardiorespiratory function.

Correlation between DNA Ploidy and Activity of Proliferating Cell Nuclear Antigen (PCNA) in a Dog with Well Differentiated Squamous Cell Carcinoma

Sung-Kwi Kang,Nam-Yong Park,Kenji Ochiai,Mun-Il Kang,Ho-Sung Cho,Chang-Baig Hyun,Sang-Ki Kim,Su-Jin Park,You-Jung Kim,Jae-Ho Jeong,Kyoung-Oh Cho 한국실험동물학회 2005 Laboratory Animal Research Vol.21 No.2

Paraffin-embedded tissue sections of surgically removed skin tumor from an eight-year-old male Shih-Tzu dog were analyzed for proliferation state using immunohistochemical detection of proliferating cell nuclear antigen (PCNA) and for DNA ploidy using flow cytometry. Histologically, tumor was diagnosed as well differentiated squamous cell carcinoma. The percentage of PCNA-positive cells, which distributed through tumor lesions, was 61.4%. In addition, PCNA-positive cells in the cancer pearls were detected only at the periphery of the neoplastic epithelial structures. The ploidy of this tumor detecting by DNA flow cytometry was clearly aneuploid. From these results, the proliferation state of this tumor determined by PCNA-immunostaining and DNA ploidy revealed malignant, even this tumor was diagnosed as well differentiated squamous cell carcinoma.

Case Reports : A Case of Granuloma Pyogenicum-Like Cutaneous Metastasis to the Fingertip in Papillary Thyroid Carcinoma

( Sung Kwi Park ),( Ho Sun Jang ),( Kyung Sool Kwon ),( Tae Ahn Chung ) 대한피부과학회 1995 Annals of Dermatology Vol.7 No.4