지상라이다를 이용한 미기록 외래종 갯쥐꼬리풀(Spartina Alterniflora)의 분포특성과 관리방안 연구 -다도해 해상국립공원 진도 남동리 해안을 사례로-

박정원 ( Jung Won Park ),김하송 ( Ha Song Kim ),장성건 ( Seong Geon Jang ),천숙진 ( Sook Jin Chun ),육관수 ( Kwan Soo Yuk ) 한국도서학회 2015 韓國島嶼硏究 Vol.27 No.3

갯쥐꼬리풀(Spartina alterniflora)은 북미 대서양 연안 뉴펀들랜드, 캐나다 남쪽에서 아르헨티나 북부의 갯벌이 원산이며, 생장이 강한 특성으로 세계의 기수지역과 해안에서 생태공학적 용도로 도입된 바 있다. 그러나 매우 빠르게 갯벌을 피복하여 자생종의 생장을 방해하고, 염습지 종다양성을 감소 시켰고, 결과적으로 과다생육으로 갯벌 무척추동물의 서식지를 잠식해 사라지게 하여 무척추동물을 먹이로 하는 조류 또한 생태계 내에서 감소키는 등 많은 환경문제를 야기 시켰다. 우리나라에서는 2008년 전후에 다도해해상국립공원에 유입된 것으로 판단된다. 현재 다도해해상국립공원 남동리 해안에서 분포하고 있는 갯쥐꼬리풀(Spartina alterniflora)군락은 습지내 총 6개의 염생식물 군락면적(8,487.7㎡) 중 75.34%의 비율(6,394.86㎡)로 분포하고 있다. 또한 2008년에 11.54㎡ 이던 분포 면적이 2015년 현재 약 550배가 늘어난 6,394.22㎡로 조사되었고 생육지 고도 범위인 0.69m~1.1m를 요인 값으로 두고 GIS 분석한 하였다. 그 결과 앞으로 확산 될 예상 면적은 12,584㎡이며 현재보다 약 6,189.14㎡가 늘어날 것으로 예측되며 우리나라에서도 역시 확산이 빠르고 넓게 늘어날 것으로 판단된다. 향후 계속 분포역이 확대 될 것으로 예상하고 관리방안을 위하여 시범 연구를 실시하였다. 갯쥐꼬리풀군락 중 일부를 첫 번째는 뿌리째 뽑아내기와 두 번째 지상부 제거 후 포장덮기 방법 등 국외사례의 문헌을 바탕으로 방재를 실시하였으나 전체 면적을 방재하기에는 많은 인력과 시간 그리고 예산이 소요되므로 다각적인 방안을 강구하여야 한다. Spartina alterniflora is native to the Atlantic coast from Newfoundland, the south of Canada and northern Argentina. There it forms a dominant part of brackish coastal saltmarshes. Due to its strong growth, the Spartina alternifolra was introduced to the rider area and coast as a use for ecological engineering. The Spartina alterniflora community can crowd out native species, reduce the biodiversity of saltmarsh and alter the environment. As a result, the invertebrates living in mud flats disappeared due to the encroaching of Spartina alterniflora, and the birds which eat off invertebrates went along as well. The Spartina alterniflora was first introduced in South Korea in 2008 and is known to have flowed in the Dadohaehaesang National Park. Compared to 2008, in 2015 the distribution area of the Spartina alterniflora has increased 550 times. (11.54㎡ in 2008 to 6,394.22㎡ in 2015). The large increase of Spartina alterniflora calls for urgent management and additionary study on the subject. Thus, this study analyzed the geo-spatial information on the Spartina alterniflora such as its distribution area, the height of habitats and expected expansion area, and can act as the preliminary data for management.

조기위암의 임상적 연구

박태준,양은수,류종철,박태군,이희승,신원창,이진호,김관엽 인제대학교 1994 仁濟醫學 Vol.15 No.1

1989년 9월부터 1993년 7월까지 인제대학교 의과대학 상계백병원에서 실시한 위내시경 소견이 조기위암이며 내시경 직시하 생검결과 선암으로 판명되어, 근치적 위절제술을 시행받은 23명의 환자에서 임상적 특징을 알아보고, 문헌고찰과 함께 보고하는 바이다. The incidence and mortality rate of stomach cancer ranks well ahead of all malignancies in Korea. The prognosis is excellent in early gastric cancer of which the overall 5 years survival rate of 85∼95% is comparative with that of advanced gastric cancer of 15∼49%. So early detection with very sensitive mordality of gastroscope and surgery is the only premise to decrease the mortality rate of gastric cancer. This report deals with the clinical aspects of 23 cases of early gastric cancer, which were confirmed with histopathologic examination of resected stomach during the 4 years from September 1989 to July 1993 at Sanggye Paik hospital, Seoul, Korea. Out of 23 cases of early gastric cancer, 14 cases were male, 9 cases were female, and the male to female ratio was 1.6 : 1. The most common type of early gastric cancer was talc type(43.5%), IIc and its combined type comprised most of them(87.0%). The most prevalent sloe of lesion was gastric angle(43.5%) and the most common direction was lesser curvature(73.9%) 19 cases of 23(78.3%) were between 1∼3cm in size, and there was no statistical significance between the size of the lesion and lymph node metastasis. Of the 9 cases with mucosal lesion, there were 2 cases with lymph node metastasis(22.2%), but 7cases(50.0% ) of 14 cases with submucosal lesion presented lymph node metastasis. Diagnostic accuracy of endoscopy on detection of early gastric cancer was 17 cases(73.9%) of total 23 cases in our study. As with other report, histopathulogic examination of resected stomach revealed adenocarcinoma, tubular type as the most common type. Frequent complaint of patients with early gastric cancer was epigastric pain(65.2%), and duration of the symptom was less than 12 months in 17 cases(73.1%) of 23 patients with early gastric cancer.

高濃度에타놀投與가 흰쥐 數種臟器의 酸素消費量과 肺容壓率에 미치는 影響

朴東盛,黃樹寬,朴載植,朱永恩 慶北大學校 醫科大學 1982 慶北醫大誌 Vol.23 No.2

Ethanol 投與로 因한 흰쥐 數種臟器의 酸素消費量(QO_2)과 血中乳酸濃度 및 肺容壓率의 變化를 살펴보기 위해서, 흰쥐를 材料로하여 50% ethanol을 體重 100gm 當 1.5㎖ 씩 經口적으로 單回投與하여 1時間에서 24時間까지 經時的으로 肝, 腎, 脾 및 腦組織의 QO_2를 測定하고, 血中乳酸濃度 및 肺容壓率를 測定하여 對照群과 比較하여 다음과 같은 結果를 얻었다. QO_2는 肝組織에서 對照의 2.11±0.10㎕O_2/hr/㎎D. W. 에 比해 ethanol 投與後 1∼6 時間에는 有意하게 높았으며, 特히 1 및 3時間에는 各各 2.81±0.15 및 2.82±0.07㎕O_2/hr/㎎D. W. 로서 最高値를 나타내었다. 腎組織은 對照의 5.33±0.26㎕O_2/hr/㎎D. W. 에 比해 ethanol投與後 1∼12時間에는 有意하게 높았으며, 그 中 3時間에는 7.47±0.32㎕O_2/hr/㎎D. W. 로서 最高値를 나타내었다. 腦組織은 對照의 4.20±0.14㎕O_2/hr/㎎D. W.에 比해 ethanol 投與後 1∼6時間에는 有意하게 높았으며, 特히 3時間에는 5.53±0.29㎕O_2/hr/㎎D. W로서 最高値를 나타내었다. 脾組織은 對照의 3.55±0.13㎕O_2/hr/㎎D. W.에 比해 ethanol 投與後 1∼6 時間에는 有意하게 높았으며, 이 中 3時間에는 5.81±0.23㎕O_2/hr/㎎D. W로서 最高値를 나타내었다. 卽 肝, 腎, 脾 및 腦組織 모두의 QO_2는 對照値에 比해서 ethanol 投與後 1, 3 및 6時間에 有意하게 높았으며, 이 中 3時間에 最高値를 나타낸 後 漸次 減少하여 12 및 24時間에는 別差異가 없었다. 腎은 12時間까지 有意하게 높았다. 그리고 各 組織의 QO_2의 比較에서 腎이 가장 높고, 다음이 腦, 그리고 脾, 肝의 順으로 나타났다. 血中乳酸濃度는 對照의 12.57±0.47㎎/㎗ 에 比해 ethanol 投與後 1 및 3時間에 各各 24.36±2.70㎎/㎗ 및 22.48±3.21㎎/㎗로서 有意하게 높았으며, 6∼24時間에는 別 差異가 없었다. 血中乳酸濃度 對 QO_2의 比는 對照에 比해 1 및 3時間에는 有意하게 높았고, 6 및 12時間에는 有意하게 낮았다. 組織의 QO_2 對 血中乳酸濃度의 比는 對照에 比해 ethanol 投與後 1時間에 有意하게 높다가 3時間에는 有意하게 낮으며, 다시 6 및 12時間에는 有意하게 높은 후 漸次 낮아져 24時間에는 特히 腎과 脾가 有意하게 낮았다. 組織의 QO_2×血中乳酸濃度에서 對照에 比해 ethanol 投與後 1 및 3時間에는 有意하게 높다가 漸次 減少하여 脾는 12時間에 有意하게 낮았다. 肺容積은 ethanol投與後 1∼2時間에서 낮은 壓力下에서는 대체로 正常보다 낮았고, 높은 壓力下에서는 對照値와 비슷했으며, 24時間에는 모든 壓力下에서 對照와 거의 같은 값을 나타내었다. 肺容壓率은 ethanol投與後 3時間까지 對照보다 增加된 후 그 後 次次 減少하였다. 以上을 綜合해 보면 血中 ethanol 濃度가 0.72gm/㎗ 가 될 程度의 高濃度 ethanol을 投與해서도 QO_2가 增加되며, ethanol投與 1∼3時間에 最高値를 나타낸 事實과 ethanol 投與로 因한 血中乳酸濃度의 增加에서 1時間에 最高値에 達한 점, 그리고 肺容壓率이 ethanol 投與 初期에 增加를 보이고 肺容積이 ethanol 投與後 24時間에 거의 對照値로 되돌아온다는 事實等은 意義있는 結果인 것으로 思料되는 바이다. In order to elucidate the effect of ethanol (EOH) administration on the oxygen consumption rate (QO_2) of some vital organs and lung compliance, ??a single dose of 1.5㎖ of 50% EOH per 100gm of body weight was administered orally to rats, and QO_2 of the liver, kidney, brain and spleen, and blood lactate level and lung compliance were measured from 1 hr to 24 hrs after EOH ingestion. The results were compared with the control group and summarized as follows: QO_2 of the liver was significantly elevated from 1 through 6 hrs after EOH ingestion compared with the control value of 2.11 0.10㎕O_2/hr/㎎ dry weight (D.W. ). The values at 1 and 3 hrs were 2.81±0.15 and 2.81±0.07㎕O_2/hr/㎎D. W. both being the peak levels, respectively. QO_2 of the kidney was significantly elevated from 1 through 12 hrs compared with the control value of 5.33±0.26㎕O_2/hr/㎎D. W. The value at 3 hrs showed the heighest value of 7.47±0.32㎕O_2/hr/㎎ D. W. QO_2 of the brain was significantly elevated from 1 through 6 hrs compared with the control value of 4.20±0.14㎕O_2/hr/㎎D. W. The value at 3 hrs showed the peak level of 5.53±0.29㎕O_2/hr/㎎D. W. QO_2 of the spleen was significantly elevated from 1 through 6 hrs compared with the control value of 3.55±0.13㎕O_2/hr/㎎D. W. The peak level was 5.81 0.23㎕O_2/hr/㎎D. W. at 3 hrs. Thus, QO_2 of the liver, kidney, brain and spleen were uniformly elevated after EOH ingestion showing the peak level at 3 hrs and returning to the control level by 12 or 24 hrs. Also, among the studied organs, the kidney showed the highest QO_2 value, followed by the brain, spleen and liver in the order named. The blood lactate was also elevated significantly at 1 and 3 hrs after EOH ingestion, the figures being 24.36 2.70 and 22.48 3.21 ㎎/㎗, respectively, compared with the value of 12.57±0.47 ㎎/㎗. The blood lactate vs. QO_2 ratio was significantly elevated at 1 and 3 hrs after EOH ingestion and was significantly lowered at 6 and 12 hrs aompared with control. The QO_2 vs. blood lactate ratio was significantly elevated at 1 hr after EOH ingestion, significantly lowered at 3 hrs, significantly elevated at 6 and 12 hrs, again significantly in the kidney and spleen, lowered at 24 hrs compared with the control value. The product of QO_2 times the blood lactate was significantly elevated at 1 and 3 hrs after EOH ingestion and gradually lowered subsequently, and significantly lowered in the spleen at 12 hrs compared with the control value. The dynamic lung volume from 1 to 2 hrs after EOH ingestion compared with the control was smaller under lower pressures but similar under higher pressures. At 24 hrs after EOH ingestion it was almost the same as the control under all pressures. The lung compliance was increased until 3 hrs after EOH ingestion but was decreased gradually thereafter. From the above, we should note that the QO_2 is increased by ingestion of EOH as concentrated as 0.72gm/㎗ showing its peak value from 1 to 3 hrs after ingestion, that the blood lactate is increased by EOH ingestion with the peak at 1 hr, and that the lung compliance is increased during the initial period with the dynamic lung volume returning almost to the control value in 24 hrs after EOH ingestion.

인체구강상피세포의 배양조건에 대한 연구

박종수,최희웅,이수관,김수복,고광삼 中央醫學社 1990 中央醫學 Vol.55 No.2

Human epithelial cell cultures were initiated from explants of normal human oral mucosa. Growth parameter and cell type were assessed by DNA concentration and morphology of the cell lines. Tissues were excised and epithelial cells isolated by collagenase digestion. Spermine was used in order to inhibit overgrowth of the epithelial cells by fibroblast. The effects of different medium formulations were compared. Cultures maintained on the same volume of RPMI 1640 and Dulbecco's modified minimum essential medium containing 10 % fetal bovine serum, 10 ?g/ml of insulin, lng/ml of somatomedin and 10 ng/ml of epidermal growth factor showed optimal and maximal growth. For each cultured human oral epithelial cell the DNA content was in the- range of 5.7 pg to 6.6 pg. This culture system provides epithelial cells that can be used for a variety of dental and biochemical studies.

돼지 하악 과두의 해면골에서 유한요소분석법으로 예측한 방향에 따른 탄성율과 3차원 골 미세지표 간의 상관관계

박관수,이삼선,허경회,이원진,허민석,최순철 대한구강악안면방사선학회 2008 Imaging Science in Dentistry Vol.38 No.2

Purpose : To investigate the relationship between 3D bone architectural parameters and direction-related elastic moduli of cancellous bone of mandibular condyle. Materials and Methods : Two micro-pigs (Micro-pig^(R), PWG Genetics Korea) were used. Each pig was about 12 months old and weighing around 44 kg. 31 cylindrical bone specimen were obtained from cancellous bone of condyles for 3D analysis and measured by micro-computed tomography. Six parameters were trabecular thickness (Tb.Th), bone specific surface (BS/BV), percent bone volume (BV/TV), structure model index (SMI), degree of anisotropy (DA) and 3-dimensional fractal dimension (3DFD). Elastic moduli of three orthogonal directions (superiorinferior (SI), medial-lateral (ML), andterior-posterior (AP) direction) were calculated through finite element analysis. Results : Elastic modulus of superior-inferior direction was higher than those of other directions. Elastic moduli of 3 orthogonal directions showed different correlation with 3D architectural parameters. Elastic moduli of SI and ML directions showed significant strong to moderate correlation with BV/TV, SMI and 3DFD. Conclusion : Elastic modulus of cancellous bone of pig mandibular condyle was highest in the SI direction and it was supposed that the change into plate-like structure of trabeculae was mainly affected by increase of trabeculae of SI and ML directions.

골다공증을 동반한 척추제 압박골절을 가진 노령환자에서 경피적 척추제 성형술 후 생활이 질 향상

박재우,공민호,이상구,송관영,강동수 The Korean Neurosurgical Society 2003 Journal of Korean neurosurgical society Vol.34 No.6

경안면 괴사성 근막염 : 증례보고

박관수,정기훈,김효언,정정권,윤규호,전인성 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.1

Necrotizing fasciitis is defined as infectious disease showing extensive necrosis of the superficial fascia with widespread involvement of the surrounding tissues and concurrent systemic toxicity. It is found commonly in the extremities, the trunk and the perineum, but shows extremely rare occurrence in the well vascularized area such as head and neck area. Occurred in the head and neck area, it is called "cervicofacial necrotizing fasciitis" (CFNF). It is a fatal disease which carries a mortality rate up to 60%. Early diagnosis, aggressive surgical debridement of necrotic tissues and massive antibiotics therapy are essential for achieving a favorable outcome. We present a case of cervicofacial necrotizing fasciitis in 35-year-old male patient with literature review.

DEM의 정확도 분석에 의한 도시 소유역의 유출해석

박진형,이관수,이삼노 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.1

본 연구는 수치지형자료의 해상도와 보간법의 변화에 따른 정확도 분석을 실시하여 도시소유역의 유출현상을 해석하고자 하였다. 수치자료는 격자크기별로 TIN 보간법을 이용하여 DEM 자료를 생성하고, 정확도 분석은 수치지도의 등고선을 이용하여 결정계수(R2)와 회귀식을 도출하였다. 검증된 DEM 자료를 사용하여 소유역구분, 면적, 유역폭, 지면경사도 등의 지형인자를 추출하여 도시유출모형에 적용시켜 여서-문수지구의 도시 소유역에 가장 적합한 유출모형을 알아보고자 한다. 모형의 적용 결과 SWMM의 유출수문곡선이 ILLUDAS의 유출수문곡선보다 실측값에 더 근사하게 나타났고, SWMM의 경우 실측값과 최대 19%, 최소 5%, 평균 13%의 오차를 나타냈다. 본 연구대상지역과 같은 도시소유역은 강우지속시간이 첨두도달시간에 미치는 영향은 미미하게 나타났다. 본 연구의 결과로 SWMM 모형이 여서-문수지역의 도시유출모형으로 적합하며 적용면에서도 더 다양한 기능과 정확성을 나타낸다고 판단된다. The purpose of this study is to analyze the urban hydrologic state by the use of GIS, resolution and interpolation. The determination coefficient(R2) and Regression Formula were derived from the contour of digital map for the accuracy, and DEM data was made by using TIN interpolation by the size of the grid. By using the observed DEM data, topographical factors were extracted from the small basin, size, the width of a basin and the slope, and were applied in the urban runoff model. Through the model, we tried to find out the most suitable runoff model in a small basin of Yosu-Munsu area. As a result of applying models to the drainage considered, the runoff hydrograph estimated by SWMM model was closer to the observed one than that estimated by ILLUDAS model. The difference between the runoff hydrograph by SWMM and the observed one is maximum error of 19%, minimum error of 5% and average error of 13%. The influence of duration in contrast to pick time is insignificant in a urban small basin. As a conclusion of this study, SWMM model was more suitable and applicable for the urban runoff model than ILLUDAS model due to its accuracy and various abilities.

골격성 Ⅲ급 부정교합 환자에서 하악골상행지 시상분할골절절단술후 상순과 하순의 연조직 변화에 관한 연구

박관수,김태열,김희광,정정권,윤규호,전인성 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.6

Purpose : The prediction of profile change as a result of orthognathic surgery remains a problem during preoperative planning because of the difference relative movements of the hard and soft tissues. This study was performed to predict the changes o( upper and lower lips after BSSRO with non-rigid fixation Material and Methods : 15 patients wish skeletal Class III malocclusion treated by bilateral sagittal split ramus osteotomy(BSSRO) and mandibular setback were selected for analysis. Cephalometric data of presurgery and postsurgery 12 months were used. Wilcoxon signed rank test, calculation of Spearmans correlation rho and simple regression analysis were performed to predict the relations between hard tissue changes and soft tissue changes. Results : The horizontal change of hard tissue Pogonion and those of lower lips showed high correlation and the ratios were from 71% to 84%. The horizontal change of hard tissue Pogonion and those of chin showed high correlation and the ratios were from 90% to 92%. The horizontal change of hard tissue Pogonion and those of upper lips showed moderate correlation and the ratios were from 7% to 18%. Conclusion : This study suggests that the changes of lower lips are highly affected by the hard tissue change of mandible and those of upper lips are moderately affected. In comparison with other studies, no significant differences were found among the fixation methods.

실험적으로 제작한 Videoensitometer의 디지탈 영상처리와 임상적 적용에 관한 연구

박관수,이상래 大韓口腔顎顔面 放射線學會 1992 Imaging Science in Dentistry Vol.22 No.2

The purpose of this study was to propose the utility which was evaluated the digital image processing and clinical application of the videddensitomery. The experiments were performed with IBM-PC/16bit-AT compatible, video comera(CCdtr55, Sony Co., Japan), an color monitor(MultiSync 3D, NEC, Japan) providing the resolution of 512×480 and 64 levels of gray. Sylvia Image Capture Board for the ADC(Analog to digital converter) was used, composed of digitized image from digital signal and the radiographic density was measured by 256 level of gray. The periapical radiograph(Ektaspeed EP-21, Kodak Co., U. S. A.) which was radiographed dried human mandible by exposure condition of 70 kVp and 48 impulses, was used for primary X-ray detector. And them evaluated for digitzed image by low and high pass filtering, correlations between aluminum equivalent values and the thickness of aluminum step wedge, aluminum equivalent values of sound enamel, dentin, and alveolar bone, the range of diffuse density for gray level ranging from 0 to 255. The obtained results were as follows ; 1. The edge between aluminum steps of digitized image were somewhat blurred by low pass filtering, but edge enhancement could be resulted by high pass filtering. Expoecially, edge enhancement between distal root of lower left 2nd molar and alveolar lamina dura was observed. 2. The correlation between aluminum equivalent values and the thickness of aluminumstep wedge was intimated yielding the coefficient of correlation r=0.999(p<0.001), the regression line was described by Y=0.9699+0.456, and coefficient of variation amounting to 1.5%. 3. The aluminum equivalent values of sound enamel, dentin, and alvolar bone were 15.41mm, 12.48mm, 10.35mm, respectively. 4. The range of diffuse density for gray level ranging from 0 to 2585 was wider enough than that of photodenstiometer to be within the range of 1-4.9.