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Kim, Ki Tack,Kim, Dong Hwan,Chung, Jun-Young,Lee, Soojeong,Joo, Jaesoon,Nah, Seong-Su,Song, Ho-Yeon,Kim, Hak-Jae Informa Healthcare 2012 Immunological investigations Vol.41 No.8
<P>In this study, we investigated whether genetic polymorphisms of the interferon gamma (<I>IFNG)</I> gene were associated with the susceptibility of ossification of the posterior longitudinal ligament (OPLL) in the Korean population. To observe the association between the <I>IFNG</I> gene and the susceptibility of OPLL, we genotyped 135 OPLL patients and 222 control subjects for a single nucleotide polymorphism (SNP, rs2430561) and a microsatellite (CA<SUB>n</SUB> repeats, rs3138557) located in the first intron of the <I>IFNG</I> gene, using the direct sequencing and gene scan method. The numbers of microsatellites (CA<SUB>13</SUB> and CA<SUB>15</SUB>) were significantly changed in the OPLL patients. A combined analysis of the genotype of rs2430561 and the number of microsatellites revealed that the OPLL was associated with frequencies of CA<SUB>13</SUB>-AA, CA<SUB>15</SUB>-AA and CA<SUB>15</SUB>-AT. Our results suggest that the <I>IFNG</I> gene may be one of the factors determining the OPLL in the Korean population. However, larger collaborative and biological studies are needed to confirm these results.</P>
( In Seong Han ),( Young Sang Suh ),( Ki Tack Seong ) 한국수산과학회(구 한국수산학회) 2013 Fisheries and Aquatic Sciences Vol.16 No.2
We investigated the short-term and local changes in the thermohaline front in the Jeju Strait, Korea, which is usually formed dur-ing winter and spring. To do so, wo compared Real-Time Observation System by Ferryboat (RTOSF) data with wind data and routinely collected oceanographic data. During February and April 2007, a thermohaline front formed in the Jeju Strait around the 13-14°C isotherms and 33.0-33.5 isohalines. The thermohaline was clearly weakened and began moving southward in mid-March. The variations in the surface temperature and salinity showed a continuous north-south oscillation of the thermohaline front with a period of 3-10 days. The speed of the short-term and local fluctuation of thermohaline front was about 5-30 cm/s. We confirmed these findings by examining the variation in the maximum temperature gradient and 14°C isotherm during the study period. These short-term and local changes had not been previously detected using serial oceanographic and satellite data. Analysis of local wind data revealed a northerly wind fluctuation with a period of 3-10 days, which was clearly related to the short-term and local changes in the thermohaline front. The short-term and local changes of the thermohaline front in the Jeju Strait originated from local changes in the winter monsoon in this area.