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직장 카르시노이드 종양에서 Ki-67 발현의 예후적 중요성
홍수민 ( Su Min Hong ),김유선 ( You Sun Kim ),문정섭 ( Jung Seop Moon ),김진남 ( Jin Nam Kim ),오명기 ( Myoung Ki Oh ),권선옥 ( Sun Ok Kwon ),정성연 ( Seong Yeon Jeong ),홍성우 ( Seong Woo Hong ),강윤경 ( Yun Kyung Kang ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.2
Background/Aims: Rectal carcinoid tumors can be resected with endoscopy, and it is important to assess their prognostic factors. We evaluated the potential of Ki-67 expression as a prognostic factor in rectal carcinoid tumors. Methods: We retrospectively reviewed the medical records of 37 patients with rectal carcinoid tumors who got endoscopic resection from January 2001 to January 2011 at Inje University Seoul Paik Hospital. We analyzed their endoscopic and histologic findings, Ki-67 expression, clinical outcome, and prognosis. Results: The mean age (±SD) of the patients was 56.3±10.7 years, and the male : female ratio was 3.6:1. The mean tumor size was 0.5±0.4 cm, 33 patients showed grade 1 tumors (89.2%) and the average Ki-67 expression was 0.7±1.2%. Thirty five patients underwent endoscopic mucosal resection, and two required endoscopic submucosal dissection. Eight patients had positive margins after resection, but no cases of lymphovascular invasion were identified. The median follow-up duration was 21.4±25.4 months, and no recurrences were observed. Conclusions: In low grade rectal carcinoid tumors which are lack of central depression on colonoscopy, the expression of a molecular marker of malignant potential, Ki-67, was low. Therefore, endoscopic resection seemed to be a safe and effective treatment for these tumors.
대두박에 대한 extrusion처리 및 formaldehyde처리가 젖소의 반추위내 in situ분해율에 미치는 영향
문여황,김기원,문점동,조광일,김병기,이성실,이상철 진주산업대학교 농업기술연구소 2001 農業技術硏究所報 Vol.14 No.-
This experiment was conducted to investigate the effect of temperature of extrusion processing on ruminal degradation characteristics of soybean meal. Four ruminally cannulated Holstein cows were employed to in situ trial and treatments were composed of soybean meals untreated(Control), extruded at 115, 130 and 155℃, and treated with 0.3% formaldehyde(HCHO). The nylon bags were suspended for 0, 3, 6, 9, 12 and 24 hours in the rumen, respectively. Animals fed the diet of 50 : 50 in concentrate and orchard grass hay at 110% of NRC(1988) requirements, and were freely access to water and mineral block. The regression equations for degradation characteristics and effective degradability(ED) of crude protein of soybean meals in the rumen were obtained as follows. Control P = 26.41 + 69.86(1-e^-0.041t) ; ED(k=0.05) = 57.89% 115℃ extrusion P = 3.39 + 44.76(1-e^-0.013t) ; ED(k=0.05) = 12.63% 130℃ extrusion P = 2.79 + 56.60(1-e^-0.015t) ; ED(k=0.05) = 15.85% 155℃ extrusion P = 1.71 + 31.48(1-e^-0.018t) ; ED(k=0.05) = 0.04% 0.3% HCHO P = 7.23 + 35.14(1-e^-0.015t) ; ED(k=0.05) = 15.34% where, P = Degradability during the time(t) suspended in the rumen, k = Passage rate at the rumen(%/hr/100). Ruminal degradabilities of dry matter, crude protein, organic matter and energy significantly (P<.01) decreased by extrusion or HCHO treatments, but did not affected by the temperature of extrusion processing. The ruminal degradation of soybean meals treated extrusion and formaldehyde, paticularly crude protein, was low beyond expectation.
엄기진,이철규,박장평,이광재,문병용,홍관이,노성규,오수일,박기동 江原大學校附設體育科學硏究所 1985 江原大學校附設體育科學硏究所論文集 Vol.- No.10
This study conducted for analyze the process of physiological variation during shooting, and produce the basic data for training prescription to the performance improvement in Air Rifle Shooting, 9 Elite Rifle shooters )College 3, High School 3, Middle School 3) in GangWeon province were tested the physiological parameter which are Electrocardiograph(E.C.G), Heart-rate(H.R), Respiratory pattern, and Trigger time by polygraph system 8 channel from Sept. 1st to Sept. 10th, 1985. Analyzed experimental results are as follows; 1. Firing at T-P wave in E.C.G, 77.68bpm in H.R)16.68% by resulting H.R), the deep size of inspiration-expiration was low, and 8.34 sec of trigger interval were appeared when the shooter acquired high score. 2. The most effective factor among physiological parameters for excellent shooting score is the inspiratory volume with decresc breathing pattern. 3. Shooting performances correlated with stability and static-dynamic balance, but flexibility effected on negative correlation.
朴鍾聲,金文圭,禹基大,劉勝憲 충남대학교 농업과학연구소 1977 農業技術硏究報告 Vol.4 No.1
1. Chemical properties of soils and inorganic compositions of rice plants were analysed to explain the acute wilting occurred in the late stage of rice variety, Yusin. The results obtained were summarized as follows. 1) The amount of K and S_iO_2 of soils where severe rice wilting occurred was lower than that of soils where rice wilting didn't occurred. 2) The amount of N and FeO of wilted rice plants was higher than that of normal rice plants while the amount of K_2O and SiO_2 and the ratio of K_2O/N of former were lower than that of letter. 2. Severe wilting was occurred only in the rice variety, Yusin, when three varieties… Yusin, Milyang #15, Milyang #23……were interplanted. The amount of organic and inorganic compositions of three varieties and chemical properties of rhizosphere soils were analysed. 1) The rice variety, Yusin, was the lowest and that of the rice variety, Milyang #15, was the highest in the level of total carbohydrate and hemicellulose. 2) Comparatively higher levels of K were observed in rhizosphere soil where Yusin was planted, while the level of the K in the plant of Yusin was the lowest.
마우스 골수 소핵 시험에 의한 디젤분진, HgCl_(2) 및 Pb(Ac)_2의 유전독성효과
허문영,최성규,유기선,손동헌 江原大學校 附設 環境硏究所 1989 環境硏究 Vol.6 No.-
The clastogenic effects of the diesel emission particle extrace(DEPE), mercuric chloride and lead acetate were examined by the mouse bone marrow micronucleus test. DEPE had a potent clastogenic effect by intraperitoneal injection with dose-response between 100 and 300mg/kg b.w.. Mercuric chloride and lead acetate also gave a clastogenic effects but mercuric chloride only had a dose-response between 1 and 3mg/kg b.w.. When DEPE was administrated with mercuric shloride or lead acetate, the frequency of micronucleated cells was slight but not significant incresase in comparision to a single treatment with DEPE alone.
박문기,김승영,김정호 한국환경과학회 2004 한국환경과학회지 Vol.13 No.12
The concentration of heavy metal were studied for the estimation of quality in herbal medicines which is Bupleuri Radix, Paeoniae Radix, Dioscoreae Rhizoma and Astragali Radix in products of north Gyeongbuk area. And we collected soils from several area in Gyeongbuk, and determined heavy metal concentration of soils by ICP. We compared with herbal medicines in products of Gyeongbuk and their soils. For the heavy metals contents of Gyeongbuk area, in Gong Jung Ri, represented the higher level, it may be due to a near the road. The Cd contents in soil was not a wide difference. For the As and Pb contents in soil, Song Sa Ri (Bupleuri Radix) represented the higher level (0.68mg/kg, 1523mg/kg). Heavy metal contents in cultured herbal medicines and their soils did not give reproducible results. But the degree of correlation between a few heavy metal contents of Dioscoreae Rhizoma and their soil showed the good transfer from the soil.