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이가순,이주찬,이종국,박원종 한국식생활문화학회 2001 韓國食生活文化學會誌 Vol.16 No.5
This study was carried out to investigate the effects of addition ratio(0, 5, 10 and 20%) of various minor ingredients(prosomillet, glutinous barley, oat, wheat, yellow and black soybean, safflower seed, chocolate etc.) on mechanical and sensory characteristics of Sulgiduk. In mechanical evaluation, hardness, cohesiveness and gumminess were increased with increasing the content of prosomillet, glutinous barley, oat and wheat to be added, and did not show any relationship the content of them to be added on yellow and black soybean, safflower seed and chocolate. In sensory evaluation, quality characteristics of Sulgiduk added with prosomillet, oat, yellow and black soybean and chocolate with 5∼10%, respectively was better than those of Sulgiduk without the minor ingredients. Change of hardness on Sulgiduk added with oat, yellow soybean, black soybean and chocolate was lower than those of Sulgiduk without them during storage of room temperature.
박기령,조성민,우가은,이기현,손혜영,임정윤,최진혁,이순남,정화순 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.2
Chronic neutrophilic leukemia(CNL) is a very rare myeloproliferative disease, characterized by sustained mature neutrophilic leukocytosis with granulocytic bone marrow infiltration, high NAP(neutrophilic alkaline phosphatase) score and absence of philadelphia chromosome, It is frequently accompanied by hepatosplenomegaly, elevated serum vitamin B_12 and uric acid level. For the diagnosis of CNL, the leukemoid reaction, especially secondary to neoplasia, infection and autoimmune diseases, should be excluded. Since Tuohy's first description in 1920, more than 50 cases fullfilling the above criteria have been reported worldwide, and 4 cases in Korea. Several authors have demonstrated the defect of intracellualr killing in the mature neutrophil and this finding correlates well with the very high incidence of fatal infection, The hemorrhagic diasthesis in CNL is caused by functional abnormality of the platelet. This disease has tendency to transform to blastic crisis and acute leukemia as in other myeloproliferative disease, but characteristically shows frequent coexistence with multiple myeloma. Until now , the therapeutic trials in CNL have been disappointing. Hydroxyrea and busulfan can control hyperleukocytosis. On the basis of functional defect in neutrophil, alpha-2b-interferon has been tried and several reports have demonstrated the clinical and functional effect of interferon on CNL. CNL is very rate hematologic disease and there are few report about general aspect of disorder. We report here a typical CNL case presenting with splenomegaly and leukocytosis with a review of the literature.
참나리(Lilium lancifolium) 구근을 이용한 민속발효주의 제조 및 생리활성
이가순(Ka-Soon Lee),김관후(Gwan-Hou Kim),김현호(Hyun-Ho Kim),이찬구(Chan-Gu Lee),이지용(Ji-Yong Lee),이희덕(Hee-Duck Lee),오만진(Man-Jin Oh) 한국식품영양과학회 2008 한국식품영양과학회지 Vol.37 No.5
백합구근을 식품으로 활용하기 위한 일환으로 구근을 첨가한 전통민속발효주를 개발하기 위하여 알코올 발효 조건을 검토하고 그의 생리기능성을 조사하였다. 백합구근을 건조분말과 생구근 상태로 첨가량을 달리하여 발효한 결과, 구근건조분말 첨가량이 증가할수록 발효 초기에는 에탄올 생성량이 무첨가구보다 낮았으나 발효 후기로 갈수록 에탄올 생성량이 높았으며, 25℃에서 10일간 발효시켰을 때 건조분말 15% 첨가 발효주와 생구근 20% 첨가 발효주의 에탄올 함량이 각각 19.4%, 19.0%이었다. 첨가량에 따른 발효주의 관능검사 결과 백합구근 건조분말을 5% 또는 생구근 20% 정도 첨가하였을 때 색, 향, 맛 및 전체적인 기호도면에서 가장 기호도가 좋았으며, 특히 건조분말을 첨가하였을 때가 생구근 첨가 발효주보다 기호도가 더 높았다. 기호도가 가장 좋았던 건조분말 5% 첨가 발효주와 생구근 20% 첨가 발효주의 생리기능성을 측정한 결과 전자공여능, SOD 유사활성, ACE 저해활성 및 tyrosinase 저해활성이 무첨가구인 대조구보다 우수하였으며, 생구근 첨가 발효주보다 건조분말 첨가 발효주가 생리기능성이 약간 더 높았다. This study was carried out to develop a new traditional alcoholic beverage by using lily scale in order to utilize lily scale as a new matter for nutritious foods. The condition of alcohol fermentation was investigated by the addition of 2.5, 5.0, 7.5, 10.0, 12.5 and 15.0% dried lily scale and 10, 20, 30, 40 and 50% raw lily scale into mash, respectively. The maximum amount of ethanol was produced when 15% dried lily scale and 20% raw lily scale were added to cooked rice at 25oC for 10 days. In overall acceptability of sensory evaluation, the LSD-5 alcoholic beverage (added 5% dried lily scale into mash) and LSR-20 alcoholic beverage (added 20% raw lily scale into mash) showed the best acceptability. Physiological functionalities of LSD-5 and LSR-20 alcoholic beverage were investigated. Electron donating ability by DPPH solution (16.5~23.2%), SOD-like activity (20.4~24.7%), ACE inhibitory activity (66.5~78.2%) and tyrosinase inhibitory activity (57.4~62.6%) of LSD-5 and LSR-20 alcoholic beverage were better than the control (non-added liquor). Moreover, acceptability and physiological functionalities of LSD-5 alcoholic beverage are better than LSR-20.
브랜칭 처리에 의한 신선편이식 둥근마의 저장 중 품질 특성
Ka Soon Lee,Bong Jae Seong,Sun Ick Kim,Moo Geun Jee,A Reum Kwon,Su Dong Kim,Hyun Ho Kim 한국약용작물학회 2017 한국약용작물학술대회 발표집 Vol.2017 No.05
Background : Dungkunma (Dioscorea bulbifera, commonly known as the air potato, air yam, bitter yam, cheeky yam, potato yam) is a species of true yam in the yam family, and has been used as folk remedy to treat conjunctivitis, diarrhea and dysentery, etc. This study was carried out to investigate shelf-life and quality of fresh-cut Dungkunma (Dioscorea bulbifera) in order to elevate utilization of Dungkunma as fresh food. Methods and Results : Before vacuum-packaging (in polyethylene/polypropylene film (100 ㎛, 15 × 20 ㎝, 75 ± 2 ㎝Hg) and storage at 2℃, Dungkunma were peeled out and cut to dice type (2.0 ± 0.5 ㎤), and then washed and blanched (30 sec at 90 ± 2℃ hot water and 2% NaCl solution) and pre-dried at room temperature, 40℃ and 50℃ for removing surface water. Each peeled dice Dungkunma were packed 50 g in polyethylene/polypropylene film (100 ㎛, 15 × 20 ㎝) with vacuum treatment (75 ± 2 ㎝Hg) and stored at 2℃ for 90 days. Hardness and adhesiveness of Dungkunma blanched by 2% NaCl and pre-dried at 50℃ (SB50) was the highest and increased and decreased, respectively, but changes was the least during storage. Lightness and yellowness of stored Dungkunma in all treatments decreased slightly and redness increased during storage but changes of color was the least at SB50. On vacuum packing, SB50 showed 1.88 log CFU/g of total aerobic bacteria during 90 days, and E. coliwas detected in all treatments during whole storage periods. Dioscin and allantoin content of SB50 was virtually unchanged during the storage. Conclusion : Consequently, the results of this study suggest that vacuum packaged Dungkunma after blanching at 2% NaCl could be effective to prolong the quality of fresh-cut Dungkunma and could be easily used.
젖산발효 처리에 의한 도라지의 Platycosides 조성 및 호흡기 질환 유발세균에 대한 항균활성 변화
Ka Soon Lee,Bong Jae Seong,Sun Ick Kim,Moo Geun Jee,Saet Byeol Park,Myeong Hee Park,Shin Young Park,Hyun Ho Kim 한국약용작물학회 2016 한국약용작물학술대회 발표집 Vol.2016 No.05
Background : Platycodon grandiflorum root(PGR) was one of the primary herbs used in a phlegm-relieving herb from the past. Purified platycoside compounds from the roots of PGR may exhibit neuroprotective, antimicrobial, anti-inflammatory, anti-cancer, anti-allergy, improved insulin resistance, and cholesterol-lowering properties. To evaluate preference and functionality of PGR extracts, PGR was fermented by several lactic acid bacteria. Lactic acid bacteria used were Leuc. mesenteroides N12-4 and N58-5, L. plantarum N76-10 and 56-12, L. brevis N70-9 and E3-8. Methods and Results : This study was performed in order to investigate the changes of platycosides, as well as the antimicrobial activities on bronchus diseases inducing bacteria(C. diphtheriae, K. pnneumoniae, S. aureus, S. pyogenes) of Platycodon grandiflorum root(PGR) fermented by using lactic acid bacteria(Leuc. mesenteroides N12-4, Leuc. mesenteroides N58-5, L. plantarum N76-10, L. plantarum N56-12, L. brevis N70-9, L. brevis E3-8). Growth of L. plantarum on PGR was the most active during lactic acid fermentation by some different strains. Total platycoside, platycoside E, platycodin A, polygalacin D2, polygalacin D and diapioplatycoside E contents of PGR fermented for 96 hours at 37℃ by Leuc. mesenteroides and L. plantarum were increased, while platycodin D and platycodin D3 were decreased. The antimicribial activity on PGR fermented by L. plantarum N56-12 exhibited a strong microbial proliferation in all four kinds of bronchus diseases inducing bacteria and was higher than non-fermented PGR extract. Conclusion : Thus, this results showed antimicrobial activities on bronchus diseases inducing bacteria and platycosides content of PGR by L. plantarum N56-12 were higher than non-fermented PGR extract.