Genetic Toxicity Test of Nanosilica by Comet assay and Mouse Lymphoma Assay

Youn?Jung Kim(김연정),Han Seam Choi(최한샘),Dong Ge Ra Mi Moon(문동그라미),Ji Hee Kim(김지희),Hye Gyeong Jo(조혜경),Jae Chun Ryu(류재천) 환경독성보건학회 2007 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

치매방지 작업기구 사용이 항산화효소 활성에 미치는 영향

조경혜,박정은,윤지윤,문세보,박효영,정인옥,이정원 서울여자대학교 자연과학연구소 2001 자연과학연구논문집 Vol.13 No.-

We developed an occupational therapy tool to maintain and improve the cognitive function for the elderly who have senile dementia. 86 elderly people took a mininal mental state examination (MMSE) for the therapy to perform the occupational therapy, and divided into three groups based on avarage ages and MMSE values. The occupational therapy was treated three times per week for 10 weeks. The results showed that there were significant differences in the performing scores before and after the treatment ; the scores for the occupational therapy were increased significantly (p<0.001) and the performing time was shortened from 6-week throughout 10-week regimen. This study was to examine the effect on the activity of antioxidant enzymes by occupational therapy. The activities of antioxidant enzymes such as catalase, Glutathion-6-phosphate dehydrogenase (G6PDH), and superoxide dismutase (SOD) were increased to the normal standard by the occupational therapy for the elderly having dementia. The recovery of activities of antioxidant enzymes was obvious in severe demented elderly compared to those in normal or mild demented elderly. These results suggest that the occupational therapy had an beneficial effect on the protection against the oxidative stress especially for severe demented elderly, and the occupational tool need to be modified so as to improve the protection against the oxidative stress for normal and/or mild demented elderly.

고등학생들의 음란물 접촉실태 및 관련요인

윤분희,정문숙,한창현,어윤국 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

본 연구는 성에 민감한 청소년들의 음란물 접촉 실태를 알아보기 위하여 1998년 11월 30일부터 12월 30일까지 경상남도 J시 소재 고등학교 2학년 학생 732명을 대상으로 설문 조사 분석한 결과는 다음과 같다. 음란물 접촉실태는 대상자가 가장 많이 접촉하는 음란물은 성인용 비디오(76.9%)이었고 성인용 만화(70.1%), 성인용 주간지(55.9%), 음란 컴퓨터 프로그램(51.2%), 포로노 비디오(50.3%), 포로노 잡지(34.4%) 및 포로노 사진집(28.1%) 순이었다. 인문계 학생이 가장 많이 접촉하는 음란물은 성인용 만화이었고, 실업계 학생은 성인용 비디오였으며 남학생이 여학생보다, 실업계 학생이 인문계 학생보다 음란물 접촉 경험이 더 많았다.(p<0.01) 음란물 접촉 시 특성을 보면 대부분 학생이 "중학교"때 처음 접촉했으며 접촉경로응 "친구를 통해서"가 가장 많았고, 접촉이유는 "호기심 때문에"가 가장 많았다. 제반 변수들에 따른 음란물 접촉과의 연관성을 알아본 결과 자위행위, 성 경험, 이성교제, 학생성적, 흡연, 음주는 모든 음란물의 접촉과 상관성이 있는 것으로 나타났다.(p<0.01) 음란물 접촉 유무를 종속변수로 하여 다중 로지스틱 분석을 한 결과는 남자일수록, 자위행위를 할수록, 학교 성적이 낮을수록, 담배를 피울수록, 술을 마실수록, 외향성일수록 음란물을 보는 경험이 더 많았다.(p<0.01) 이상 결과들을 볼 때, 청소년들을 음란물로부터 보호하기 위해서는 성적충동을 올바르게 표출하고 승화할 수 있도록 개개인의 취향에 맞는 운동이나 취미활동을 권장하고 이를 개발할 수 있도록 도와주어야 할 것이며 유해환경에 대한 규제를 강화하여 학생들이 살고 잇는 사회의 성문화 정화에 모두 관심을 가져야겠다. This study was conducted to examine the sex-sensitive adolescents' actual condition of contact with lecherous things from November 11th to December 20th, 1998 with 732 high school sophomores in Chinju, Kyungsangnam-do. And the results are as follows. According to the actual condition of contact with lecherous things the most lecherous thing subject group came into contact was adult videos(76.9%) and adults cartoons(70.1%), adults magazines(55.9%), lecherous computer programs(51.2%), porn videos(50.3%), porn magazines(34.4%) and porn photo collections(28.1%) in highest order. The most lecherous thing academic high school students came into contact was adults cartoons and that of business high school students was adults videos and contact experiences to it of male students and business school students were higher than those of female students and academic school students respectively(p<0.01%). In view of students' characteristics of contact with lecherous things, most students made first contact with them in their middle school years and from their friends curiosity. In the result of study of relevance to the contact with lecherous things due to all sorts of variables, it shows that masturbations, sex experiences, intersexual acquaintances, school records, smoking and drinking are related to the all contacts with lecherous things(p<0.01). In the result of Multiple Logistic Analysis with the presence of contact with lecherous things as subordinate variable, the more they are men, doing masturbations, the person with bad school records, smoking, drinking and extroversive the more they are inclined to contact with lecherous things(p<0.01). To protect adolescents from the access to lecherous things, in view of above results, we have to encourage and help adolescents to enjoy and develop sports or hobbies of their own to express and purify their sexual impulses right. And we also have to concern the purification of sexual culture of the society in which students live by strengthening our regulatory systems for unsound circumstances.

임신부의 인플루엔자 백신 접종률 및 관련요인

김미정,이승연,이광수,김아름,손동욱,정문현,박신구,박지현,이병익,이진수 대한감염학회 2009 감염과 화학요법 Vol.41 No.6

Background : During seasonal influenza epidemics and previous pandemics, pregnant women have been at increased risk for complications related to influenza infection. Although influenza vaccination has been widely recommended to pregnant women and immunocompromised hosts, the vaccination rate is presumed to be low in pregnant women. This study was aimed to evaluate the vaccination rate and factors associated with Influenza vaccination among pregnant women, who are at high risk for developing complications from the influenza. Materials and Methods : This study was carried out by telephone survey from April, 2007 to August, 2007. Women who were in their second trimester of pregnancy or above,- during October, 2006 and February, 2007, the recommended vaccination period, and had given birth at Inha University Hospital were selected as the study population. Immunization status, general understanding, and factors associated with vaccination were evaluated. Results : Among a total of 506 eligible pregnant women, 227 (44.8%) responded to the questionnaires. The influenza vaccination rate among the pregnant women was only 4% (9/227). Major reasons for not receiving vaccination were first, not awaring the necessity of immunization during pregnancy (48.5%, 110/227) and second, misunderstanding that it is prohibited during pregnancy (36.1%, 82/227). The major factors that influenced the compliance of vaccination were correct understanding and doctor's recommendation on the influenza immunization during pregnancy. Conclusions : The influenza vaccine coverage on pregnant women was very low and the awareness of influenza vaccination during pregnancy in general was inaccurate. Shift in perception is required and this can be achieved by educating the pregnant women on the safety and efficacy of vaccination. In addition, doctors' active encouragement to vaccination is highly recommended.

뇌실외 배액술 관리에 대한 이해 및 업무수행 실태

김정숙,윤미선,송소이,이지은,문경선,고지운,임분남,김경희,박경숙 중앙대학교 간호과학연구소 2001 중앙간호논문집 Vol.5 No.2

The objective of this study was to investigate the managing realities of EVD and provide a descriptive survey with the attempt to obtain basic data needed for the standardization of EVD management. For that purpose, 220 questionnaire copies were distributed to those nurses who were working with intensive care units at university hospitals, general hospitals, semi-general hospitals in Seoul, Kyongki-de and local areas. Of 158 returned questionnaire copies, 139 were used for analysis. Data were collected during the term of academic seminars of Neurosurgery Nursing Committee and KICA (Korea Intensive Care Association), ranging from Oct. 26 through 27. 2000. The tools utilized a structured questionnaire form consisting of 21 questions on general characteristics, the level of understanding, the level of work performance, standard management guidelines, etc. The data collected were analysed with frequency, percentage, mean vague, chi -square test using the SPSS 10.0 program Findings were revealed, as follows: For managing the prevention of EVD infection, aseptic technique was found to be of the most importance (48.9%),'the technique should be carried out at an operation room'(92.8%), but it was actually performed at intensive care units (over 51.5%). 'The term of antibiotics use should be less than 7 days' (81.8%), while it was actually executed for less than 7 days (49.5%). 'The proper time of quittance from it should be within less than 7 days'(74.1%) but actual quittance was executed only by 51.1%. 'Set exchange is needed' by 54.0% but actual exchange was implemented merely by 28.1%. 'The subject of management should be nurses' was reflected by 40% but actually 52.0% were carried out. As a result of hating analysed the understanding of the management of EVD by general characteristics, a significant difference was found in the necessity for set exchange by hospitals, in the time of quittance of a catheter, and in ablution items by work experience. The result of hating analysed the work performance levels of EVD management by general characteristics revealed that a significant difference in administration facilities of medicine by the classification of hospitals, especially the use of antibiotics and the quitting time of a catheter by the classification of intensive care units, and in the use of antibiotics and ablution items by the standard management guidelines.

Cu-base合金의 Boron化에 의한 表面改質

徐昌濟,文貞勳,林秉守,朴洙用 成均館大學校 科學技術硏究所 1993 論文集 Vol.44 No.1

Boriding has been investigated by means of a surface heat treatment burying in amorphous boron powder under an argon gas atmoshere. The hardness of the boronized surface on the Ag and Cu alloys show the range of Hv 600 to Hv 1000 depending on chemical compositions. Moreover, in order to investigate the effect of each alloying element in pure Cu on increase in boronized surface hardness, various Cu-binary alloys, which contained Mn, Ti, Si, Zn or Al element, were boronized. The boronized surface of the alloys has been investigated from metallographic and X-ray analyses and hardness distribution.

천안시 도로변의 NO₂및 SO₂오염도 측정에 관한 연구

손부순,염윤기,김종오,문정숙 한양대학교 환경및산업의학연구소 2000 環境과 産業醫學 Vol.9 No.1

This study's goale to find out the degree of the air pollution caused by vehicle emissions and to collect basic data for alternative plan in the improvement of the quality of the air by searching for the quality of the air around the road(in front of Chunan station, Terminal intersection, at Bangiugan five forked road, Chunanro intersection) in Chunan. NO2 and SO2 were measured as a object for this study in winter time and in summer time respectively. There has been an rapid increase in population and industrial complex has been built up in Chunan area. Therefore an increase in the number of vehicles and the use of domestic fuel has followed by that. So more studies of that and the effort for the improvement in the quality of the air will have to be made.

前腕部 經穴 取穴에서 骨度分寸法과 一夫法의 比較 硏究

박히준,채윤병,차웅석,박종배,이혜정,이향숙,인창식,고형균,김수영,최일환,김강식,문정배,배기태,유경환,육근영,정병주,손인철,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Background : The cun measurement System, an essential and convenient method in locating acupoints, has been widely used in the practice of acupuncture. However, traditional cun measurement has been criticized for its lack of reliability. Objectives : The purposes of this study are to determine if one cun measured by the directional methods have a consistency with that of proportional methods and to investigate which factors are related with these differences, especially in forearm. Methods : The distance between the elbow crease and the wrist crease of forearm was compared to a reference value of one cun obtained by the directional method. In this method, one cun is one third of the distance between index finger and Small finger of a subject, measured at proximal interphalangeal joint. In addition, to investigate the factors influencing the differences between these two methods, we measured the height and body weight and calculated body mass index (BMI). Finally we analyzed the factors correlated with these lengths by linear regression test. Results : The results showed that one cun obtained by the directional methods were significantly different from one cun by the proportional methods in forearm. It was demonstrated that the length acquired with the directional method was more correlated with body weight and body mass index, while the length obtained by the proportional method was more correlated with the height.

혈전 발생의 위험 인자가 없는 환자에서 급성 신우신염에 의해 유발된 신정맥 혈전증 및 폐색전증

이광수,김아름,이승연,정주홍,김미정,이진수,정문현,홍기천,조순구 대한감염학회 2009 감염과 화학요법 Vol.41 No.5

Renal vein thrombosis (RVT) is not an uncommon condition amongst patients with nephrotic syndrome or malignancy. Septic pulmonary embolism (SPE) is associated with risk factors such as intravenous drug use, pelvic thrombophlebitis, and suppurative processes in the head and neck. However, acute pyelonephritis is a rare cause of RVT and SPE. Case reports on RVT and SPE due to acute pyelonephritis are rare. In most of the earlier cases, patients had underlying conditions such as diabetes mellitus, renal carcinoma, calyceal stones, and hyperhomocysteinemia. We report a case of acute pyelonephritis complicated by RVT and SPE that occurred in a patient without any predisposing risk factors for thromboembolism. RVT and SPE were diagnosed using computed tomography and ventilation/perfusion scan. The patient recovered with antibiotics and anticoagulation therapy without any surgical interventions.

황색포도상구균 신속 검출용 간이 진단키트

김기영,박샛별,문지혜,이상대,이새롬,장윤정 충남대학교 농업과학연구소 2013 농업과학연구 Vol.40 No.2

This study was performed to develop a rapid test kit for pathogenic Staphylococcus in various samples. The rapid detection kit has been fabricated based on nitrocellulose lateral-flow strip. Colloidal gold and Staphylococcus antibodies were used as a tag and a receptor, respectively. Manually spotted Staphylococcus antibody and anti-mouse antibody on the surface of nitrocellulose membrane were used as test and control lines, espectively. Feasibility of the rapid kit to detect Staphylococcus aureus in samples were evaluated. The intensity of the color of the tes line started to increase with the samples in which higher concentration of the cells were contained. The sensitivity of the sensor was 106 cfu/mL Staphylococcus spiked in PBS. Also, the rapid test kit could detect 105 cfu/mL of Staphylococcus in chicken meat extract.