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수요자의 요구와 아파트 단위세대 평면계획의 상관관계에 관한 연구 : 용인지역을 대상으로
신중진,박성진,김명훈,김태엽 대한건축학회 2004 대한건축학회논문집 Vol.20 No.2
The purpose of this study is to define the correlation between consumer's needs appearing diversely in recent years and characteristics of apartment unit plan derived from categorizing composition forms of unit plan. The results of this study are as follows; ① The separation and connection of public zone have relation to use space economically with living room in the center. ② The opened space composition is reflected to an increase in size and openness of the living room. ③ The variability by the hierarchy change of space appears into the introduction of variable designs through light wall and family room. ④ The protection of privacy and communication have relation to the separation of master zone and conversion of inner room to family communication space. ⑤ The diversity and individualization of rooms appear into giving a special function to rooms increased by the extension of bay. ⑥ the extension and connection of service space are reflected to an increase in size of balcony and storage and the flexibility of utility space. ⑦ The recovery of emotionality has relation to the introduction of interior garden.
Clinical Usefulness of Serial Neutrophil Geletinase-Associated Lipocalin as a Predictor for Aki
( Jung Yeop Lee ),( Seung Yong Park ),( Yeong Hun Choe ),( So Ri Kim ),( Seoung Ju Park ),( Heung Bum Lee ),( Yong Chul Lee ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Background: Plasma neutrophil geletinase-associated lipocalin (NGAL) has been regarded as one of the valuable markers of development of acute kidney injury (AKI) in ICU admitted patients. However, clinical significance of short-term change of plasma NGAL was not clearly investigated. Methods: 50 patients who admitted intensive care unit (ICU) was included by prospective manner. We analyzed plasma NGAL level by Triage immunoassay on ICU admitted time and 12 hours after. Change of estimated glomerular filtration rate (by MDRD equation) and need of renal replacement therapy was investigated. Patients with chronic kidney disease were excluded. Results: Persistent elevation of plasma NGAL above 1,000 ng/mL on 0 and 12 hours was significantly associated with need for early renal replacement therapy. Patient with increased level of NGAL at 12 hours showed unfavorable outcome which is related to renal replacement therapy or progressive renal impairment (13/25; 48% of patients). Conversely, 2/17 (11.8%) of patients had poor renal outcome when NGAL decrease more than 20% from baseline at 12 hours after ICU admission. On multivariate analysis, baseline NGAL and ΔNGAL0-12 hr was independent predictors of unfavorable renal outcome. However, ΔNGAL0-12 hr did not significantly correlated with the change of glomerular filtration rate between day 1 and day3. Conclusions: Our data suggest that measurement of early serum NGAL change may be useful marker in predicting the renal impairment and need for renal replacement therapy in intensive care unit.
Preparation and in vivo evaluation of immediate-release pellet containing celecoxib solid dispersion
Park, Chun-Woong,Tung, Nguyen-Thach,Son, Dao-Danh,Kim, Ju-Young,Rhee, Yun-Seok,Kang, Seung-Yeop,Park, Shin-Ae,Hwang, Kyu-Mok,Oh, Tack-Oon,Ha, Jung-Myung,Chi, Sang-Cheol,Park, Eun-Seok 한국약제학회 2012 Journal of Pharmaceutical Investigation Vol.42 No.3
The aim of this study was to make use of small size of immediate-release (IR) pellet and amorphous state of solid dispersion to increase solubility of celecoxib (CLX), a drug in BCS class II. Primary, binary and ternary solid dispersions were developed to choose the final components for solid dispersion. A ternary novel solid dispersion was prepared by incorporation of one aqueous soluble polymer (povidone k17; PVP 17PF), Methacrylate copolymer-based gastric soluble polymer ($Eudragit^{(R)}$ EPO) and one pH modulator (MgO). This combination was effective to increase solubility in pH 1.2 up to 25-30 %. The mechanism of solubility enhancement was proven by DSC, PRXD, and FT-IR. Accordingly, hydrogen bonding or electrostatic interaction of CLX with PVP/$Eudragit^{(R)}$ EPO was the main cause to form the amorphous state of CLX within polymer cluster which increasing solubility of drug. Besides, MgO played an important role to change microenviroment for solid dispersion. Pellets containing this solid dispersion were prepared by extrusion and spheronization technique. Effect of four kinds of additive (calcium hydrogen phosphate dihydrate,$NaHCO_3$, crospovidone, and sodium dodecyl sulfate) on dissolution of CLX from IR pellet was also determined. Because of highest dissolution rate, formulation using sodium dodecyl sulfate was used for pharmacokinetics study. Solid dispersion-IR pellet formulation presented bioequivalence and lower variability in comparison with reference product.
한정엽(Jung Yeop Han),전덕인(Duk In Jon),홍현주(Hyun Ju Hong),정명훈(Myung Hun Jung),유제현(Je Hyun Yoo),박재용(Jae Yong Park),류상현(Sang Hyun Rhyu),홍나래(Na rei Hong) 대한노인정신의학회 2018 노인정신의학 Vol.22 No.2
Objective:Delirium is very common in orthopedic elderly patients and increase comorbidity and mortality rates. By controling the risk factors of delirium, prevention strategy can be effective and reduce negative outcomes. The purpose of this study was to explore the usefulness of delirium risk assessment with some simple collateral questionaires. Methods:The subjects were 50 elderly patients (≥65 years old) who admitted to a department of orthopedic surgery for operations of lower extremity fractures. They were evaluated with Diagnostic and Statistical Manual of Mental Disorders, fifth edition, Confusion Assessment Method and Korean Dementia Screening Questionnaire (KDSQ) by psychiatrists. The demographic data, medical histories, and orthopedic chart were checked through medical records of patients. Results:27 subjects (54.0%) were diagnosed as delirium. There was a significant difference between delirium group and control group with all KDSQ scores. Depressive category of KDSQ score had the highest correlation (coefficient=0.399) and can be independent risk factor of delirium (p=0.045). Conclusion:Cognitive impairment and depressive symptoms have high correlation with delirium. We found that just a few questions of cognitive impairment and depressive symptoms by caregivers
변증 진단 체계 개발 및 응용 연구 분석-한방 비만변증을 중심으로-
박정식 ( Jung Sik Park ),송윤경 ( Yun Kyung Song ),황의형 ( Eui Hyoung Hwang ),정원석 ( Won Suk Chung ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ),신승우 ( Seung Woo Shin ),박태용 ( Tae Yong Park ),장보형 ( Bo Hyoung Jan 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.2
Objectives The purpose of this study is analyzing internal research trends of oriental obesity pattern identification in korean literature based on obesity pattern identification questionnaires, development and application of Pattern Identification System to help solve problems of future researches.Methods6 Korean databases were searched for articles of oriental obesity pattern iden-tification, irrespective of publication year and 13 studies were reviewed. An analytical meth-od such as descriptive statistics and an actual number and percentage was used. Results We collected 13 studies. 4 studies were published in 2012 and 2008, the highest number of studies. 7 Clinical studies were the major research method. The Studies were classified according to the characteristics and design. 5 studies were about research of analysis and improvement of oriental obesity pattern identification questionnaire, the most number of studies. 4 studies were about research of observational studies in clinical on obe-sity pattern identification. 3 studies were about research of intervention studies in clinical on obesity pattern identification and 1 study was about clinical practice recommendation. Conclusions Establishment of obesity pattern identification system and its clinical appli-cation could lead to standardizing obesity pattern identification and clinical practice guideline. Applied on other diseases, obesity pattern identification system could also lead to improving treatment rate, contributing to the development of clinical practice guidelines and academic field of research. (J Korean Med Rehab 2014;24(2):107-114)
수중정찰용 자율무인잠수정의 운동 모델링 및 시험을 통한 계수 조정
이필엽(Phil-Yeop Lee),박성국(Sung-Kook Park),권순태(Soon Tae Kwon),박상웅(Sangwoong Park),정훈상(Hunsang Jung),박민수(Min-Soo Park),이판묵(Pan-Mook Lee) 한국해양공학회 2015 韓國海洋工學會誌 Vol.29 No.6
This paper presents the dynamic model of an AUV called HW200 for underwater surveillance. The mathematical model of HW200 is briefly introduced, considering its shape. The maneuvering coefficients were initially estimated using empirical formulas and a database of vehicles with similar shapes. A motion simulator, based on Simulink of Mathworks, was developed to evaluate the mathematical model of the vehicle and to tune the maneuvering coefficients. The parameters were finely tuned by comparing the experimental results and simulated responses generated with the simulator by applying the same control inputs as the experiment. The velocity of HW200 in the tuning process was fixed at a constant forward speed of 1.83 m/s. Simulations with variable speed commands were conducted, and the results showed good consistency in the motion response, attitude, and velocity of the vehicle, which were similar to those of the experiment even under the speed variation. This paper also discusses the feasibility of its application to a model-based integrated navigation system (INS) using the auxiliary information on the velocities generated by the model.
박동엽 ( Dong Yeop Park ),박애라 ( Ae Ra Park ),정은희 ( Eun Hee Jung ),배재형 ( Jae Hyeong Bae ),이국천 ( Guk Cheon Lee ),황보원 ( Bo Won Hwang ),이민권 ( Min Kwon Lee ) 한국가축위생학회 2009 韓國家畜衛生學會誌 Vol.32 No.4
Porcine proliferative enteritis (PPE) is a transmissible gastroenteric disease caused by Lawsonia intracellularis. Clinically, PPE causes hemorrhagic diarrhea and sometimes death in growing pigs, but when the disease progresses to a chronic phase, the infected pig no longer displays significant symptoms. The purpose of the present studies were carried out to determine L. intracellularis in the pig farms and slaughter house, in Gyeongnam area. A survey of proliferative enteritis in pig was conducted using polymerase chain reaction (PCR) testing method, total 1,495 samples. PCR products showed a specific band at the 210bp, 329bp in the specimens of feces and mucosal scraping. Of 420 fecal specimens, 113 (26.9%) were identified as positive to PPE. Of 1,075 mucosal scraping specimens, 109 (10.1%) were identified as positive to PPE. Of total 1,495 specimens, 222 (14.8%) were identified as positive to PPE.
PD제어 기법을 적용한 어뢰형 무인잠수정(HW200)의 선수각 및 심도제어기 설계와 실해역 성능 검증
박성국(Sung-kook Park),이필엽(Phil-yeop Lee),박상웅(Sangwoong Park),권순태(Soon T. Kwon),정훈상(Hunsang Jung),박민수(Min-su Park) 제어로봇시스템학회 2015 제어·로봇·시스템학회 논문지 Vol.18 No.12
This Paper considers the heading and depth control problem for an underactuated AUV (Autonomous Underwater Vehicle) HW200. The HW200 is a torpedo-type AUV that is developed from Hanwha corporation R&D Center for military operation such as MCM (Mine Counter Measures). The HW200 controls horizontal and vertical motion with two stern plane and two rudder plane. It is well known that fine control of an AUV motion is not easy because of model uncertainties, highly nonlinear and coupled motions. To overcome those kind of uncertainties, a number of control methods have been presented. In this paper, the motion controllers of the HW200 are designed using PD controller design method based on the linear and perturbed model of the typical 6-DOF equations of an AUV, and confirmed the effectiveness of the controller through simulations and field test.
E10의 경항부 근육통 완화에 대한 효과; 전-후 비교, 예비 임상 연구
정동훈 ( Dong-hoon Jung ),김혜정 ( Hye-jung Kim ),김정섭 ( Jung-sup Kim ),이귀선 ( Gui-sun Lee ),박원형 ( Won-hyung Park ),차윤엽 ( Yun-yeop Cha ) 대한한의학회 한방재활의학과학회 2016 한방재활의학과학회지 Vol.26 No.3
Objectives The purpose of this study is to investigate the efficacy of E10 on the relief of cervical myalgia. Methods This study is a one group pre-post, pilot trial test. After the approval of institutional review board (IRB), we have recruited 25 patients suffering from cervical myalgia. 23 patients (2 patients dropped out) was treated by using E10 on the cervical muscle and acupuncture points, three times a week for a total of two weeks from February 2016 to April 2016. Evaluations of VAS for bothersomeness of neck pain (VASB), VAS for pain intensity (VASP), NDI, SF-36, X-ray, thermography, etc. before and 1 week after treatment were carried out. The primary outcome measure was the VASB, measured 1 week after the end of the therapy. Results VASB scores was significantly decreased from 72.5±9.9 to 50.4±9.9. VASP scores was significantly decreased from 71.5±10.5 to 48.5±18.3. Results showed significant improvements in VASB, VASP, NDI, SF-36 from the baseline. However, in X-ray, thermography, there was no singnificant difference. Conclusions This study demonstrates the effectiveness of E10 treatment for relieving cervical myalgia. (J Korean Med Rehabil 2016;26(3):119-128)