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      • 캡슐내시경과 단일풍선 소장내시경으로 진단된 공장의 간질종양 1예

        송도경,심기남,태정현,김경진,송명은,송하응,윤혜원,정가영,정정화 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2

        Gastrointestinal stromal tumors (GISTs) are common mesenchymal tumors that arise in the wall of the gastrointestinal tract. We report a case of obscure gastrointestinal bleeding due to a GIST of the jejunum successfully documented by videocapsule endoscopy (VCE) and single-balloon enteroscopy (SBE). A 36-year-old man with hematochezia was referred for further evaluation of no evidence of bleeding focus on esophagogastroduodenoscopy and colonoscopy. A VCE showed a suspicious ulcerative hyperemic mass that located in about 1 hour apart from duodenal second portion. SBE revealed a nonbleeding 4×2 cm mass with an ulcer at the proximal jejunum. The patient underwent laparoscopic resection without complication. Histological examination revealed a well circumscribed, dumbbell-shaped firm mass comprised of spindle cells. Immunohistochemical staining for CD 117 was diffusely positive, whereas staining for S-100, CD 34 and MIB-1 was all negative. It was confirmed to be a low-grade GIST at the proximal jejunum.

      • 청소년의 스마트폰 중독과 우울 및 불안과의 관계

        김경은,김필송,민주연,박수경,신서인,이지은,정해인,조호정,최정원,최정인 이화여자대학교 간호과학대학 2013 이화간호학회지 Vol.- No.47

        Purpose: The purpose of this study was to investigate the relationships between the degree of smart phone addiction among adolescents and their depression and anxiety levels. Method: In this study, 379 high school students were selected using the convenient sampling method. The instruments used for this study were smart phone addiction measure, the CES-D (Center for Epidemiological Studies-Depression Scale), and the STAI (State-Trait Anxiety Inventory). Data were analyzed using the SPSS 20.0 program with descriptive statistics, t-test, ANOVA with Scheffe test, and Pearson’s correlation coefficient. Result: The mean score for smart phone addiction was 40.45±17.27, depression was 36.56±9.58, state anxiety was 44.00±9.61, and trait anxiety was 45.70±9.75. There were significant differences between the degree of smart phone addiction and the following variables: gender (t=-4.953, p<.001), hours of smart phone use per day (F=12.259, p<.001), types of frequently used features (F=3.485, p=.008), and satisfaction level for smart phone (F=5.18, p<.001). There were statistically significant relationships (p<.001) among degree of smart phone addiction, depression level, and state and trait anxiety levels. Conclusion: The results of this study suggested that there was a significant relationship between smart phone addiction and mental health, specifically, depression and anxiety among adolescents. Further research is needed to develop nursing strategies to provide care for adolescents who frequently utilize smart phones.

      • KCI등재

        유용성 도료와 수용성 도료의 유해성 비교에 관한 연구 : 자동차 보수용 도료를 중심으로

        권은혜,김광식,오정룡,최정근,정윤석,이유진,김은아,송세욱,정호근 한국산업위생학회 2001 한국산업보건학회지 Vol.11 No.1

        The purpose of this study is to substitute water-based painting materials for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters. This study assessed the exposure of organic solvents to the painters using water-based and solvent-based painting materials and compared compositions, painting processes and the health hazards of the application of these alternative painting materials. The results of this study are as follows. 1. solvent-based painting materials used in motor-repairing process consist of various organic solvents, which consist primarily of toluene, xylene, ethyl benzene, ethyl methyl bezene, trimethyl bezene, ethyl acetate, butyl acetate, methyl isobutyl ketone, 2-ethoxy ethanol, 2-ethoxy ethyl acetate and toluene-2.4-diisocianate and the others. These organic solvents are know as health-hazardous substances. But water-based painting materials are high-solid, low-solvent ones and consist of such two organic solvents as 2-butoxy ethanol and 2-heptanone and the others. 2. The painters using solvent-based painting materials in motor-repairing process are exposed to various organic acetate, methyl isobutyl ketone, trimethyl benzene, 2-ethoxy ethanol, and 2-ethoxy ethyl acetate. But the painters using solvent-based ones are only exposed to 2-butoxy ethanol and 2-heptanone. 3. By using water-based painting materials in stead of solvent-based painting materials containing health-hazardous organic solvents, the exposure of such organic solvents in the painter's breathing zone can be largely prevented. 4. This study recommends water-based painting materials as substitutes for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters.

      • KCI등재
      • KCI등재

        과산화효소를 이용한 백혈구 측정용 뇨 검사지 제조에 관한 연구

        송은영,변시명,김희정,김종완,정태화,이홍수,최인성 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 1996 Journal of biomedical laboratory sciences Vol.2 No.2

        백혈구에 존재하는 과산화 효소를 이용하여 뇨 중 백혈구의 수를 간접적으로 측정하는 새로운 방법의 뇨 검사지를 개발하였다. 과산화 수소원으로서 포도당 산화효소와 포도당을, 색원체로서 tetramethylbenzidine을 처리하여 백혈구 측정용 뇨 검사지를 제조하였으며 검출한계는 10cells/㎕ (5 cells/hpf)이었다. 개발된 백혈구 측정용 뇨 검사지로 뇨를 분석하였을 때 뇨 1/㎕당 10-25cells의 백혈구가 존재할 경우에는 2분내에 연녹색을, 75-250 cells/㎕에서는 녹색을 보였고 500 cells/㎕ 이상에서는 녹청색을 보였다. 172명의 환자뇨를 대상으로 뇨중 백혈구 수치를 현미경 측정 결과와 본 연구에서 개발한 백혈구 측정용 뇨 검사지와 현재 수입 시판 중인 미국의 A사 제품과 B사 제품으로 분석 비교한 결과 좋은 상관관계를 보였다. 이와 같은 평가분석을 통하여 볼 때 본 연구에서 개발한 백혈구 측정용 뇨 검사지는 에스테라아제를 이용한 백혈구 측정용 뇨 검사지와 함께 뇨중 백혈구를 스크리닝 하는데 효과적임을 알 수 있었다. A new test strip to detect leukocytes using the myeloperoxidase in urine was developed. The reagent strip contains tetramethylbenzine, glucose and glucose oxidase. The detection limit was between 10 cells per 1㎕ urine(5 cells/hpf), showing greenish yellow color in the range of 10-25 cells/㎕, green color in the range of 75-250 cells/㎕, greenish blue color in the range of 500 cells/㎕. The result can be obtained within two minute. The performance of the new method was evaluated by comparing the results of microscopic examination and other commercial products. Good correlations were shown between the values obtained by our urine strip and those by other commercial products with 172 urine samples. The results were proven that new methods were useful as primary screening reagents to detect leukocytes in urine.

      • KCI등재

        전자정부 환경하의 기록관리체계 개선방향

        송희준,김은정 이화여자대학교 2004 사회과학연구논총 Vol.12 No.-

        본 연구에서는 전자정부사업 추진에 따라 행정정보와 문서자료들을 체계적으로 관리하기 위한 전자적 기록관리의 추진 실태와 전망을 살펴보고자 한다. 새로운 정보화 환경으로 전자정부와 기록관리는 단순히 행정업무에 정보기술을 도입하는 문제가 아니라 정보기술관리 이상의 행정업무 방상과 관련 법 ∙ 제도에 있어서의 변화는 물론, 이에 따른 공무원과 국민의 의식 및 행태 변화를 수반한다. 따라서 전자정부와 기록관리는 하드웨어와 소프트웨어 등 플랫폼, 인터넷 등 통신, 정보보안 기술 등 기술 시스템과, 업무 프로세스 재구축 (BPR), 행정 조직과 기능의 변화, 관련 법 ∙ 제도의 제 ∙ 개정, 정보보호와 정보격차 해소 등과 같은 사회 시스템 사이에 상호 작용하는 하나의 시스템(socio-technical system)으로 인식되어야 한다. This paper looks at the realities and prospect of electronic data management in e-government in order to deal with administrative information and documents. E-government is not simply to introduce information technology into administrative process, but to be accompanied by a variety of changes in business process reengineering and legal and institutional rearrangements. Therefore, several social factors including administrative process and function, legal and institutional rearrangements, information security, and so on, In addition to technical elements such as hardware, software, and other standard issues have to be considered in building e-archives and records in e-government.

      • KCI등재

        이트라코나졸의 경구용 액제 처방화

        정기섭,홍지웅,최기송,지상철,박은석 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.4

        The oral bioavailability of itraconazole is variable and low in fasting state. This is mainly due to the low solubility of this drug. Bioavailability can be improved by changing the formulation and it is general that the liquid preparations show greater bioavailability than the solid dosage forms such as tablets and capsules do. Benzyl alcohol-water binary mixture showed the excellent solubilizing capacity for itraconazole but the release of the drug from the preparation needs to be enhanced. In this study, various nonionic surfactants and hydrophilic polymers, poloxamers, were screened to investigate their effects on the release of itraconazole from the liquid preparations. Poloxamer 407 showed the most enhancing effect on the drug release and the release rate was proportional to the amount of poloxamer 407 added. A liquid preparation of itraconazole, consisting of benzyl alcohol/water/poloxamer 407 ternary solvent system, released more than 80% of the total drug amount at 5 min and showed the possibility of a new formulation development.

      • KCI등재후보
      • 화성군 우정면 석천리 일대의 해수침투경로 파악을 위한 물리탐사 기술의 적용

        송무영,김양수,이성은,최정은 忠南大學校 環境問題硏究所 1998 環境硏究 Vol.16 No.-

        본 연구는 경기도 화성군 우정면 석천리 일대의 경작지역을 대상으로 전기 비저항 탐사를 실시하여 해수 침입의 진위여부를 판단하고자 하였다. 본 연구지역에서는 현재 해수가 침투중 인가를 파악하기 위하여 슐럼버져배열 전기비저항 탐사를 실시하였고, 가능한 해수침투의 이동경로를 파악하고자 쌍극자배열 전기비저항 탐사를 실시하였다. 본 탐사의 해석은 컴퓨터 역산과정을 통해 얻어진 자료를 활용하여 저비저항의 방향성을 찾고자 하였다. 쌍극자 탐사의 수직단면도와 슐럼버져배열 전기탐사의 전기비저항 수평분포도에 의한 해석결과는 연구지역의 남서방향에서 동북방향으로 저비저항대가 천부에서 심부로 연장 발달되어 있음을 알 수 있다. 본 탐사에서 얻어진 자료는 해수침입의 가능지역과 해수침입 가능경로를 파악하는데 기초자료로 활용될 수 있을 것이다.

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