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      • 경북 최초의 신장이식 1례

        이중현,김용섭,이정호,이창우,김상욱,이문섭,오민구,하달봉,이경섭 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

        신장이식은 환자의 삶의 질을 높이고 거의 정상적인 사회생활을 가능하게 함으로써 말기신부전 환자의 3가지 신대체 요법(혈액투석, 복막투석, 신장이식) 중에 가장 효과적이고 각광받는 치료법이라 할 수 있다. 최근 들어 의료기술과 의학의 발달로 신장이식의 성공률은 과거에 비해 비약적으로 높아지고 있으며 국내에서도 점차 신장이식수술을 받는 환자가 증가하고 있으나 서울이나 다른 대도시에 비해 의료환경이 열악한 중소도시나 지방의 병원에서는 아직도 시행하지 못하고 있는 형편이다. 이에 저자들은 경북 최초로 자체 의료진에 의해 고혈압과 말기 신부전으로 동국대 포항병원에서 혈액투석을 받고 있던 32세의 남자환자에게 부인으로부터 신장을 제공받아 신장이식을 성공적으로 시행하였기에 문헌고찰과 함께 보고하고자 한다. Kidney transplantation is the preferred treatment modality for many patients with end-stage renal disease (ESRD), because it offers improved quality of life over both hemodialysis and peritoneal dialysis. Patients who do well after transplantation generally report improvement in vitality and freedom to return to the style of life that they experienced before their progression to ESRD. Recently, the success rate of kidney transplantation is greatly being increased as the surgical technique and immunosuppressive drugs are developed. Kidney transplantation is also popular in Korea which has good result. But, until now the general hospitals which are located at small city can't try the kidney transplantation because they don't have proper facilities and experts. We firstly experienced a case of kidney transplantation in a 32 years old man with hypertension and chronic renal failure at KyoungBuk province. So we report this case with references.

      • 실험적 간암의 전암병변에 관한 면역 조직화학적 및 유세포 계측 연구 : C-ras, C-erb B2, Proliferating Cell Nuclear Antigen 및 C-myc의 변동 Expression of C-ras, C-erb B2, PCNA, and C-myc

        이중달,김종만,고영혜,김재영 한양대학교 의과대학 1994 한양의대 학술지 Vol.14 No.1

        To investigate the role of oncogenes in the hepatocarcinogenesis, author had undertaken an experimental study of hepatic carcinogenesis induced in 50 rats by feeding 2-acetylaminofluorene(2-AAF) in diet. The animals were sacrificed at 2, 4, 6, 8, 12, 16, 27, and 36 weeks after 2-AAF administration, and each liver was immunostained with monoclonal antibodies for c-ras, c-erb B2, and proliferating cell nuclear antigen(PCNA), and analysed by flow cytometry for c-myc oncoprotein. 1.The control livers were negative for expression of c-ras, c-erb B2, and c-myc oncoprotein, and positive for PCNA in 0.2% of hepatic cells. 2.The oval cells were markedly proliferated at 4 weeks after 2-AAF administration. They eventually became differentialted into bile ductular cells and small hepatocytes. 3.The oval cells and small hepatocytes showed high positive rate for PCNA with strong reaction for c=ras, c-erb B2, and c-myc oncoprotein whereas bile ductular cells failed to react for c-ras and c-erb B2. 4.Most hepatocytes in regenerative nodules lost the expression for c-myc, c-ras, and c-erb B2, although the oncoproteins persisted in some hepatocytes in the nodules. 5.Hepatocellular carcinoma of trabecular type and undifferentiated carcinoma were induced by 36 weeks after 2-AAF administration. The undifferentiated carcinoma cells expressed both PCNA and c-erb B2 oncoprotein rather strongly. Above results suggested that in the early phase of the experiment, c-ras, c-erb B2, and c-myc oncogenes were activated and stimulated to proliferation makes the oval cells to e transformed into malignant cells. However, the findings that most oval cells were differented into reversible cells in regenerating nodules suggested that overexpression of these oncogenes might not be sufficient to obtain irreversible phenotype of malignant cells. Also strong expression of oncoproteins and high PCNA positive rate in small hepatocytes and in a few cells of the hyperplastic nodules suggested that the pathway of the cancer might go through the development of oval cells to small hepatocytes to nodules and eventually to cancer. However, the results that most hepatocytes in the nodules lost oncoproteins and development of undifferentiated carcinoma in the absence of nodule formation suggested that the hepatocellular carcinoma arose from oval cells directly without a morphologic intermediate.

      • SF6/N₂압축가스중에서 支持絶綠物의 沿面放電 特性

        李鉉雨,高義石,金正達 慶南大學校 附設 工業技術硏究所 1987 硏究論文集 Vol.5 No.-

        直流 平等電界중에서 電氣的 負性氣體인 SF?가스와 N₂가스를 混合시킨 경우 破壤電壓과 PMMA 스페이서가 존재하는 경우 沿面放電特性을 760〔torr·cm〕이하에서 조사 검토한 結果를 要約하면 다음과 같다. 1. SF?, N₂,SF?/N₂가스 混合가스중에서 스페이서가 없는 直流平等電界의 破壤强度는 파센곡선에 따랐으며 電極과 스페이서의 接觸狀態가 完全한 경우도 거의 직선적으로 증가했다. 2. 스페이서가 없는 경우와 스페이서와 電極이 完全한 경우는 가스 種類에 관계없이 極性效果는 나타나지 않고 電極과 스페이서간에 接觸缺陷이 있는 경우 負極性 閃絡電壓은 正極性의 경우보다 낮았다. 3. pd≥500〔torr·cm〕범위에서는 스페이서 效率이 낮게 나타나고 pd?200〔torr·cm〕범위에서는 閃絡電壓이 가스壓에 依存한다. 4. SF?30〔%〕N₂70〔%〕混合가스의 경우 N₂단독가스와 비교해 볼 때 약 2.2배의 絶綠强度를 나타내므로 N₂가스에 소량의 SF? 가스를 混合하여도 閃絡電壓은 매우 높게 된다. Surface Breakdown Characteristics of Spacer in SF?/N ₂Compressed Gas. The flashover voltages have been investigated for PMMA spacer and unbridged-gap in SF?/N₂gas mixtures up to the value of 760(torr·cm), The gap was stressed by DC source The results obtained are as follow; 1. The flashover voltages for an unbridged gap and for a spacer in SF?/N₂gas mixtures follow the Paschen's curve. 2. The polarity effects was not observed in both unbridged gap and a spacer which had perfect contacts with an electrodes. The flashover voltages for negative polarity are lower than those for positive polarity in case of imperfect contacts. 3. 3% flashover voltages is decreased by the putting a spacer which had perfect contacts with an electrodes. The spacer which has gap void shows the lowest flashover voltages. 4. The lowest spacer efficiency was obtained with higher gas pressure & large amount of N₂content. The flashover voltages depend on the gas pressure rather than the spacer efficiency at low valuse of pd. 5. The flashover voltage of gas mixtures of N₂with SF? are relatively high, even though the amount of SF? gas content is small.

      • 복수의 자율이동로봇의 협조운동에 관한 연구

        정원갑,최유식,서호철,이석규,이달해 영남대학교 공업기술연구소 1999 工業技術硏究所論文集 Vol.27 No.2

        This paper proposes a fuzzy algorithm for cooperative behaviors of multiple autonomous mobile robots. Each robot makes decision of his behavior based on the information obtained by ultrasonic sensors to measure the position and angles of other robots. To enhance the industrial applicability of the suggested algorithm, we add disturbances of error angle caused by wheel steering when autonomous mobile robot navigates toward next destination point. This algorithm uses the position and velocity information of both the nearest robot and other robots within the detective radius of sensor with different weighting. Based on the fuzzy rule table and fuzzy inference, we obtain the rotational angle of the robots. The effectiveness of the proposed algorithm is shown by some computer simulations where a group of mobile robots encircles with equi-interval. In addition each robots is given weighting value to avoid the wall. Finally, the suggested algorithm shows that the more robots exist, the more effective it is.

      • KCI등재
      • 비정상교통류에서의 운전자 경로학습 : Systems Dynamics Approach

        李鐘達,金重秀 嶺南大學校 環境問題硏究所 1998 環境硏究 Vol.18 No.1

        경로유도는 교통의 수급문제를 해결하기 위한 방법 중의 하나이다. 본 연구는 공공기관의 경로유도에 있어서 비정상교통류상태에 있는 운전자들의 경로학습을 스텔라 시뮬레이션 언어로 Systems Dynamics화 한 것이다. Systems Dynamics는 경영과학이나 산업공학의 분야에서 의사결정과정의 수치해석적 또는 이론분석적 관리에 의한 조직적 접근법이다. 본 연구에서의 Systems Dynamics는 비정상교통류에서 운전자의 행태를 분석하기 위한 유용한 시뮬레이션법이라 생각된다. 특히, Systems Dynamics는 동적인 변화의 상황에 뛰어난 적응성을 보여주었다. The route guide is a method which is one of the solution of the traffic demand problems. For the route guide by a public corporation, this study is modeling of the route choice behavior under nonstationary traffic condition with systems dynamics approach using the Stella simulation language. The systems dynamics is systematic approach supplemented by the decision making process of management to the numerical and theoretical analyses in the field of the operations research or the industrial engineering. In the results of this study, the systems dynamics seems to be one of the useful simulation methods for the analysis of a driver's behaviour under nonstationary traffic condition. The systems dynamics approach, especially, shows a good and adaptive respondence at a dynamical changeable conditions.

      • 부모-자녀간의 의사소통이 중학생의 자아 개념에 미치는 영향

        이정신,이달석 조선대학교 사범대학 부설 교과교육연구소 2001 敎科敎育硏究 Vol.4 No.1

        The purpose of this study was to explore that an effect on middle school pupil's SelfConception by the parent-children's communication which was categorized the communication frequency and the acceleration communication. In order to actualige the purpose of this study, problems of this study were specified as follows: 1) In what shape does the reality of parent-pupils' communications frequency and acceleration communication appear? 2) In what shape does the reality of pupils' self-conception appear? 3) To what parent-pupils' communications frequency and pupils' self-conception relate? 4) To what does parent-puils' acceleration communications and pupils' self-conception relate? 5) To what does parent-pupils' communications frequency and acceleration communication to pupils' self-conception with parent's academic career, job an pupils' sex relate? Subjects of this study was sampled middle school pupils 292 persons with stralified random at 4 middle school in Gu-Rye region and one middle school in Young-Gwang region of Jun-nam province. The instruments of this study were the communciation inventory for parent-son, daughter made by Gim Young-Gu(1992) and the self-conception inventory made by S대 Woo-Sug(1992). DAta were treated with using the Descriptive, F-test and T-test of SPSS-PC^+ Majors findings of this study were as follow: 1) Relating parent-pupils' communications,all most pupils' communications with parent per one or two in a week and one third of pupils' have not communications with parent, in acceleration-communications with parent not many pupils' is occupied at high level and almost pupils' are performing with the normative communication, so teacher should-inform parent, about the knowledge, the method of communications. 2) The order of pupils' self-conception developed is the social, moral, physical self-conception and academic, personality of self conception are developed low. So adults should concern the developing pupils' self-conception harmony. 3) Relating communications frequency and pupils' self-conception, the more is communications frequency, ohysical , moral, personality and academic self-conception develop the more.

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