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      • KCI등재

        교수자 첨삭논평에 대한 글쓰기 학습자의 반응 양상 고찰

        박준범(Park, Jun-beom) 한국어문학회 2017 語文學 Vol.0 No.135

        The purpose of this article is to investigate writing student’s response to the comments provided by the teacher. This paper first categorizes the comments of the teacher into the two aspects: the focus and the mode, and then it attempts to classifies the student’s response to the teacher’s comments into two types: acceptance and rejection. In this article, the students’ responses of acceptance and rejection are analyzed in accordance with the teacher’s comments, which deal with either the focus or the mode. First, the student’s acceptance of the teacher’s comments is as follows. As for the comment that emphasizes the focus, the students showed the acceptance rate of 62.64%. The students with the comment of in the focused area showed somewhat higher acceptance rate of 76.00% when the comment was shaped as the ‘command’. On the other hand, the teacher’s comments in ‘criticism’ yielded a somewhat lower acceptance rate of 54.69%. Those fact shows that, when the students react positively about the teacher’s comments dealing with the focus, they prefer the commentary which suggests a relatively straightforward and clear suggestions in the ‘command’. In addition, the comments asking for ‘correction’ was found to be effective way of helping students to revise, especially when the teacher uses the modes of ‘closed question,’ ‘correction,’ ‘command,’ and ‘criticism.’ On the other hand, the students acceptance of the comment regarding the mode, the acceptance rate when applying the style of ‘command’ was higher than that of the other modes. And there are symmetrical relationship among ‘closed question’, ‘open question’, ‘criticism’ and ‘qualified criticism’, which are the ways of asking for answers among the modes of commentary provided to writing students. When the teacher provides comments on ‘context’ or ‘organization,’ the student tends to easily take the comment regardless of the modes of ‘closed question’ or ‘criticism.’ Therefore, it is effective for the teacher to consider such a tendency when composing comments for students. Secondly, the rejection of the comment provided by the teacher is analyzed as follows. In the rejection of the comment regarding what it focuses, the students showed the rejection rate of 17.94% against the teacher’s comments. The rejection of the comment regarding the focus did not show a biased rejection rate. However, the ‘correction’ as the modes of comment does not effectively induces the student’s participation, while the modes of ‘open question,’ ‘advice,’ and ‘qualified criticism’ showed the higher rejection rate. The acceptance and rejection as the students’ responses were partially symmetrical but not completely symmetrical. In the rejection aspect of writing students with the comment on the mode, the method of ‘command’ showed a somewhat lower rejection rate. This signifies that the students are likely to reject to the comments in the mode of ‘criticism.’ The response of rejection shows a slight difference between ‘closed question’ and ‘open question,’ while it reveals smaller gaps among ‘closed question’ and ‘criticism’, ‘open question’ and ‘qualified criticism.’

      • KCI등재후보

        甘豆湯 전탕액과 구성약물이 배양심근세포 박동수에 미치는 영향

        박준배,권강범,황인진,김우경,김희찬,오광수,이호섭,류도곤 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.4

        To test the protective effect of herbal medicine on myocardial damage against adriamycin-induced myocardiotoxicity, cytotoxicity of adriamycin was examined using MTT assay and protective effect of herbal medicine in the presence of water extract of Gamdu-tang, Gamigamdu-tang, or single constituents of these prescriptions was examined using counting of beating rate. The results of these experiments were obtained as follows : Adriamycin resulted in a decrease in viability and beating rate in cultured myocardial cells. Gamdu-tang water extract shows effects of protection from the cardiocyte toxicityinduced by adriamycin treatment such as increases beating rate. Gamigamdu-tang water extract shows the similar protective evvect as shown in gamdu-tang treatment on the decreasing of beating rate induced by adriamycin. Radix Glycyrrhizae, Semen Glycine, and Folium Phyllostachyos water extract shows a significant effect of protection for cardiotoxicity induced by adriamycin in cultured myocardial cells. These results show that adriamycin elicits toxic effects in cultured myocardial cells derived from neonatal mouse, and suggest teat water extract of gamdu-tang, gamigamdu-tang, Radix Glycyrrhizae, Semen Glycine, or Folium Phyllostachyos is very effective in the prevention of adriamycin-induced cardiotoxicity/

      • KCI등재후보

        당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

        한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

        Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

      • 성인에서 발병한 과면역글로불린 E 증후군 1예

        이재천,박주상,윤지열,정두련,문희범,우준희,류지소 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

        과민역글로불린 E 증후군은 영유아기부터 반복적인 부비동, 호흡기감염 및 농양의 형성, 습진성 피부 질환 및 혈청 면역글로불린 E의 상승을 보이는 드문 질환이다. 특징적으로 농양은 발열이나 균혈증을 동반하지 않으며, 포도상구균이 흔한 원인균이며, 배농 및 항균제 정주로 효과적으로 치료된다. 향후 병태생리 및 치료에 대한 연구가 필 요하다. 저자들은 성인기에 발병한 반복적인 피하 농양 형성, 습진성 피부질환, 혈청 면역글로불린 E의 상승 등으로 과면역글포블린 E 증후군으로 진단된 증례를 국내 최초로 보고하는 바이다. Hyperimmunoglobulin E syndrome, rarely reported, is a syndrome of hyperimniunoglo-bulinemia E. eczematous skin lesion, and recurrent staphylococcal infections on respiratory system and skin with abscess formation, mostly from early in life. The abscess is not accompamed with fever and bacteremia, that is a characteristic 'cold abscess' We report a case of 56 year-old woman who manifested this syndrome from adulthood. with the review of literatures.

      • 비장경색이 동반된 쯔쯔가무시병 1예

        오종찬,이범주,장재현,원경준,박경희,김동민,박치영,정춘해 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

        Tsutsugamushi disease is an acute febrile illness caused by Orientie. tsutsugsmushi. It is characterized by fever, myalgia, lymphadenopathy, and rash. And it can be easily diagnosed by characteristic eschar and serologic testing. Nearly all of the patients with tsutsugamushi disease improve with antibiotics such as doxycycline. However, the fatality rate of untreated cases is seven to ten percent. Splenic infarction is not common disease which is caused by occlusion of the main splenic artery or any of its branches. It is mainly caused by emboli that arise from cardiovascular disease, but sometimes by regional thrombosis associated with leukemia, myeloproliferative disorder, sickle cell anemia, pancreatitis, splenic torsion and septicemia. We experienced one case of tsutsugamushi disease with splenic infarction, which was improved after doxycycline treatment finished.

      • 당뇨병 환자에서 발생한 대장 가성폐색증 1예

        이재형,강준구,박준성,이창범,박용수,김동선,함준수,김태화,안유헌,박충기 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.2

        가성 장폐색은 기계적인 폐색부위가 없이 복부팽만과 구토 등 장폐색의 증상과 징후가 나타나는 질환을 말하며, 선행원인을 찾을 수 없는 원발성 가성 장폐색과 다른 질환에 이차적으로 발생하는 속발성 가성 장폐색으로 나눌 수 있다. 당뇨병은 잘 알려진 속발성 가성 장폐색의 원인이지만 실제로 당뇨병에 의한 가상 장폐색의 발생 빈도는 매우 드문 것으로 보이며, 가성 장폐색의 적절한 치료에 대해서는 아직 논란이 있다. 저자들은 2형 당뇨병 환자에게 대장에 국한된 급성 가성 장폐색을 진단하고 보존적 치료를 시행하여 호전된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Colonic pseudo-obstruction is a disorder characterized by gross dilatation of the colon in the absence of any anatomic lesions, which obstructs the flow of the intestinal contents. Diabetes is a well known cause of secondary pseudo-obstruction but its prevalence in rare and not well understood. A 59-year-old woman patient was admitted due to abdominal distension and nausea of a day's duration. She was diagnosed with diabetes 15 years ago, but the condition had been poorly controoled. On the abdominal radiographs, there were marked small and large bowel dilatation with the, exception of the descending colon. Our initial diagnosis was mechanical obstruction, but the possible causes were not found. Also, we could not find another cause of the secondary pseudo-obstruction, with the exception of diabetes mellitus. Thus, she was diagnosed with a diabetes induced intestinal pseudo-obstruction. The colonic dilatation was resolved by conservative management and she became comfortable in 10 hospital days, and was subsequently discharged.

      • KCI등재

        한국어 판 구조화 임상면담도구 개발 : 신뢰도 연구

        한오수,안준호,송선희,조맹제,김장규,배재남,조성진,정범수,서동우,함봉진,이동우,박종익,홍진표 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

        연구목적: 정신장애의 정확한 진단과 평가는 임상에서뿐만 아니라 신뢰성 있는 연구를 위해서도 매우 중요하다. Structured Clinical Interview for DSM-IV(SCID)는 임상전문가들이 사용하는 진단도구로서, 비교적 짧은 시간에 정확한 진단을 내릴 수 있다. 본 연구는 한국어판SCID를 개발하고 그 신뢰도를 평가하기 위해 수행되었다. 방법: 국문학자가 포함된 번역위원회를 통하여 연구용판 SCID를 번역한 후, 정신과 의사 2인과 임상심리학자 1인에게 한국어판SCID 실시방법을 교육시킨 뒤 한국어판SCID를 이용한 면담의 평가자간 신뢰도 (interrater reliability)를 검증하였다. 면담 대상은 1999년 2월에서 3월까지 2개 병원 정신과에 치료중인 환자 90명(남:41명, 여:29명)이었다. 결과: 현재 장애(current disorder) 평가에서 주요 우울장애, 기분부전장애, 정신분열병, 알코올 남용 및 의존, 기타 물질 남용 또는 의존, 여러 불안장애들 및 섭식장애 등과 같은 대부분 장애의 kappa값은 .70이상으로 매우 높았다. 그 이외의 양극성 장애, 망상장애, 광장공포증, 감별 불능 신체화 장애 및 건강염려증의 kappa값도 .69에서 .40사이로 수용할 수 있는 정도였다. 평생 장애(lifetime disorder)에서는 양극성 장애(k=.69)와 감별 불능 신체화장애(k=.59)를 제외한 다른 모든 장애의 kappa값이 .70이상이었다. K-SCID 면담시 Ⅰ축 질환에 대하여 흔하게 다중 진단이 내려졌으며, 평균 진단 수는 1.5∼1.7개로 나타났다. 결론: 한국어판 SCID는 신뢰도가 높은 진단도구로 생각되며, 향후 정신질환의 정확한 진단과 임상연구에 유용하게 사용될 수 있다. Objectives: Accurate diagnosis and assessment for psychiatric disorders is crucial for research, as well as for clinical practice. Structured Clinical Interview for DSM-Ⅳ(SCID-RV) is a less time-consumimg and more accurate structured diagnostic interview form. It can be used by clinical professions and is known for a reliable diagnostic tool. Present study was conducted to develop Korean version of SCID-RV and to test the inter-rater reliability. Methods: The authors have translated original SCID-RV into Korean, and revised in parallel with sociocultural background of Korea. Ninety patients from two psychiatric hospitals, both outpatient and inpatient, were interviewed and rated independently by three raters. Results: The kappa coefficients for most of illnesses, such as major depressive disorder, dysthymia, schizophrenia, alcohol abuse and dependency, anxiety disorder and eating disorder were excellent(>0.70) in the evaluation of current disorders. And the kappa coefficients for bipolar disorder, delusional disorder, agoraphobia, undifferentiated somatoform disorder, and hypochondriasis were acceptable(>0.40) in the evaluation of current disorders. In the evalua-tion of lifetime disorders, the concordant rates of all the diagnoses except bipolar disorder and undifferentiated somatoform disorder were excellent. Lack of hierarchy in DSM-Ⅳ allows for multiple Axis I diagnoses. Mean numbers of Axis I diagnoses per subject assigned by the three raters were 1.5-1.7. Conclusions: Our findings confirm that SCID-RV yields highly reliable diagnoses. SCID-RV is recommended for accurate diagnosis in clinical practice and research on psychiatric disorders.

      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • 다양한 함불소가스들의 고비점 용매에 관한 용해도 측정 및 엑막에 의한 분리

        최평호,이상학,김철웅,김범식,김광주,이정민,박인준 한국공업화학회 2002 응용화학 Vol.6 No.2

        The solubility of various fluoro-gases in high boiling-point solvents, n-Cnh_2n+_1OH(6<n<10)and ionic liquids(+ ions: 1-Buty 1-3-methy1-imidazolium, 1-Ethy1-3-methy1-imidazolium, - ions:BF_4, PF_6, S_6F_6, F_6O_4S_6) were measured at temperatures from 0 to 30℃, at total pressures up to 4 bat Solubility increased significantly with the decrease of n in n-Cn_2N+OH and showed no such a difference in the types of ionic liquids, Especially, the solubility of R22 gas in these solvents increases rapidly with increases in pressure and decreases in temperature, whereas other fluoro-gases were showed a little solubility Liquid-supported membranes were prepared with these solvents and polymer matrix and were applied to the separation of fluoro-gases including R22 gas. A high permeability and selectivity were exhibited in R22 gas against other fluoro-gases.

      • 급성 백혈병 환자에서 감염증의 양상 및 예후인자에 관한 연구 : 1988년∼1995년까지

        정희진,김병수,신상원,김열홍,김우주,김민자,김준석,박승철,김권범 대한감염학회 1998 감염 Vol.30 No.3

        목적 : 급성 백혈병의 경우 골수기능이 억제되고 항암화학요법에 따른 골수기능 저하로 감염의 위험이 증가하며 감염의 치료가 환자의 생존에 큰 영향을 미치게 된다. 이에 저자들은 1988년부터 1995년까지 고대 구로병원에 급성 백혈병으로 입원했던 환자들 중 입원 기간 내 감염이 있었던 경우를 대상으로 하여 감염의 위험인자 및 감염증의 예후를 후향적으로 분석함으로써 향후 급성 백혈병환자의 감염의 치료에 대한 지침을 얻고자 하였다. 방법 : 급성 백혈병으로 확진된 환자들 중 감염병에 이환된 경우를 대상으로 하여 각각을 미생물학적 확인감염, 임상적 확인감염, 그리고 설명 불가열로 구분하였다. 각각의 경우에서 감염 당시의 호중구 수, 호중구 감소 기간, 항암화학요법과의 연관성, 감염 병소, 배양된 검체 및 원인균, 선택적 소화관 살균법의 사용여부 및 골수회복 여부 등을 조사한 후 환자의 예후와 어떤 관계가 있는 지 조사하였다. 결과 : 연구 대상은 총 113예로 남녀비는 46:67 이었고 평균연령은 34±13세, 진단은 급성 골수성 백혈병 (AML)이 84예, 급성 림프구성 백혈병(ALL)이 29예였으며, 감염시 평균 호중구수는 663±1678/㎣이었고, 호중구 감소 기간은 평균 18±13일이었다. 감염양상은 항암화학요법과 연관된 감염이 84예로 대부분이었고 미생물학적 확인 감염이 40예로서 35%였으며, 폐렴과 원발성 패혈증이 각각 20예와 19예로 가장 많았고, 카테터 연관 감염이 7예로 나타났다. 배양된 균주는 E. coli가 10예(25%)로서 가장 많았으며, 전체적으로 E. coli, P. aeruginosa, K. pneumoniae 등의 그람음성균이 63%로 대부분을 차지하였으나 최근 그람양성구군 및 진균의 분리율이 증가하는 양상을 보였다. 감염증의 예후를 분석한 결과 진균 감염인 경우나 호중구 감소 기간이 긴 경우 사망률이 높았으며 그 중에서도 골수 기능이 회복 여부가 환자들의 생존과 통계적으로 유의한 연관이 있었다.(P=0.01). 결론 : 급성 백혈병 환자들에서의 감염은 관해유도화학요법 후 초래되는 호중구 감소와 유의한 관계가 있으며, 폐렴 및 패혈증의 임상양상을 보이는 경우가 흔하고, 원인균별로는 그람 음성균이 주류를 이루나 최근 그람 양성균 감염이 증가하는 추세를 보였다. 감염의 예후 인자로는 진균 감염인 경우나 호중구 감소 기간이 긴 경우 사망률이 높았으나 골수 기능의 회복여부가 결정적인 역할을 하는 것으로 나타나, 향후 급성 백혈병 환자의 치료에 있어 감염 빈도의 감소와 감염에서의 조속한 회복을 위해서는 골수 기능의 회복에 중점을 두어야 할 것으로 사료된다. Background : Infection is one of the most important and fatal complications in patients with acute leukemia. The characteristics of infection in acute leukemic patients are different from those in other diseases by the lack of normal inflammatory responses or distinct clinical evidence except fever. To improve the outcome of acute leukemia, it is very important to recognize the risk factors, patterns and prognostic factors of acute leukemia. Methods : We analyzed retrospectively the patterns of infection from 113 febrile patients with acute leukemia from January, 1988 to December, 1995. To determine the prognostic factors and the outcome of infection, the following variables were analyzed: the presence of neutropenia, use of chemotherapeutic agents, type and site of infections, isolated organisms, gastrointestinal decontamination, duration of neutropenia, and bone marrow recovery. Results : Out of 113 febrile patients with acute leukemia, 84 infection episodes(74%) occurred after chemotherapy. The mean duration of neutropenia was 18±13 days. The incidence of microbiologically-documented infection(MDI) was 35%(40/113). Pneumonia was the most common infection(26%), followed by primary sepsis(24%), catheter-related infection(9%). In cases of MDI, 63% were caused by gram-negative bacteria, followed by gram-positive bacteria(28%), and fungi(10%). Escherichia coli(25%) was the most common isolated in MDI. Regarding the prognostic factors in cases with infections, the recovery of bone marrow function was the only statistically significant factor(P=0.01). Conclusion : Infection has been a major cause of morbidity and mortality in acute in acute leukemic patients. To prevent infection and thereby improve the prognosis of acute leukemia, restoration of bone marrow function at early stage is important.

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