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Repeated dose 90-day oral toxicity of 20nm, negative charged Zinc Oxide Nanoparticles in SD rats
Seon-Ju Kim,Eun-Ho Maeng,Su-Hyun Kim,Jin-Hee Lee,Sung-Sup Shin,Jun-Ho Kim,Taek-Jin Lee,Nak-Won Seong,Hak-Su Park,Sang-Bum Koh,Eun-Jeong Lee,Yu-Ri Kim,Meyoung-Kon Kim 한국실험동물학회 2013 한국실험동물학회 학술발표대회 논문집 Vol.2013 No.2
Hedgehog signaling between cancer cells and hepatic stellate cells in promoting cholangiocarcinoma.
Kim, Younjoo,Kim, Myeong-Ok,Shin, Jin Sun,Park, Sun Hoo,Kim, Sang Bum,Kim, Jin,Park, Su Cheol,Han, Chul Ju,Ryu, Ji Kon,Yoon, Yong Bum,Kim, Yong-Tae Raven Press 2014 Annals of Surgical Oncology Vol.21 No.8
<P>Aberrant Hedgehog (HH) signaling activation is important in cancer growth and mediates the interaction between cancer cells and the surrounding stromal cells. This study investigated the role of HH signaling on the growth of cholangiocarcinoma (CC), focusing on the interaction of CC cells with stromal cells.</P>
Kim, Yeon-Ki,Kim, Jeong-Sook,Cheong, Pil-Joong,Kim, Min-Jeong,Lee, Tae-Ho,Joo, Joung-Su,Kim, Ju-Kon,Nahm, Baek-Hie,Song, Sang-Ik The Korean Society for Applied Biological Chemistr 2009 Applied Biological Chemistry (Appl Biol Chem) Vol.52 No.3
Designing high density DNA arrays representing all the genes of an organism could be limited when the entire genome sequence of the organism is not available or if only a limited number of ESTs are available. In an effort to prepare coding sequences as DNA sources for a microarray, we found that coding region enriched genomic DNA libraries can be produced by S1 nuclease treatment of partially denatured genomic DNA. Sequence analysis of about 1,000 clones using BLASTN and BLASTX searches showed that 46% of the clones in the library have regions which share significant similarity with sequences deposited in the rice EST and nr data bases. These data suggested that clones produced in this library could be directly used as PCR templates, where the resulting PCR products could be spotted on slides for microarray analysis. This technique might be applicable in designing a high density DNA array for an organism whose entire genome sequence is not available.