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Dual specificity phosphatase 6 as a predictor of invasiveness in papillary thyroid cancer.
Lee, Jung Uee,Huang, Songmei,Lee, Min Hee,Lee, Seong Eun,Ryu, Min Jeong,Kim, Soung Jung,Kim, Yong Kyung,Kim, Seul Young,Joung, Kyong Hye,Kim, Jin Man,Shong, Minho,Jo, Young Suk Scandinavian University Press 2012 European journal of endocrinology Vol.167 No.1
<P>The genetic mutations causing the constitutive activation of MEK/ERK have been regarded as an initiating factor in papillary thyroid carcinoma (PTC). The ERK-specific dual specificity phosphatase 6 (DUSP6) is part of the ERK-dependent transcriptional output. Therefore, the coordinated regulation of the activities of ERK kinases and DUSP6 may need to be reestablished to make new balances in PTC.</P>
Comparison of Eight Crops for Bioenergy and Forage in Korea
Joung Kyong Lee,Hyung Soo Park,Hee Chung Ji,Jong Guen Kim,Won Ho Kim,Sang-Hoon Lee,Ki-Won Lee,Sei Hyung Yoon,Ki Yong Kim,Min Woong Jung,Yeon Sik Choi,Young Chul Lim 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08
In this study, we conducted to select the promising crops for both uses in the bioethanol and forage production in Korea. The result indicated t㏊t Natsukaje (guinea grass), Gwangpyeongok (corn), Jumbo (sorghum×sudangrass hybrid), SS405 (sorghum×sorghum hybrid), Millex32 (pearl millet), Jeju barnyard grass), Alamo (switch grass) and Selection75 (klein grass) showed the production of biomass from the highest to the lowest in order. However, the order of the production of quality forage was, from the highest to the lowest, Natsukaje (guinea grass), Jumbo (sorghum×sudangrass hybrid), SS405 (sorghum×sorghum hybrid), Gwangpyeongok (corn), Millex32 (pearl millet), Selection75 (klein grass), Jeju (barnyard grass), and Alamo (switch grass). We concluded the Natsukaje (guinea grass) was the best bioethanol crop, and also the Natsukaje (guinea grass) was the best for forage production.
Thyroid dysfunction associated with follicular cell steatosis in obese male mice and humans.
Lee, Min Hee,Lee, Jung Uee,Joung, Kyong Hye,Kim, Yong Kyung,Ryu, Min Jeong,Lee, Seong Eun,Kim, Soung Jung,Chung, Hyo Kyun,Choi, Min Jeong,Chang, Joon Young,Lee, Sang-Hee,Kweon, Gi Ryang,Kim, Hyun Jin The Endocrine Society 2015 Endocrinology Vol.156 No.3
<P>Adult thyroid dysfunction is a common endocrine disorder associated with an increased risk of cardiovascular disease and mortality. A recent epidemiologic study revealed a link between obesity and increased prevalence of hypothyroidism. It is conceivable that excessive adiposity in obesity might lead to expansion of the interfollicular adipose (IFA) depot or steatosis in thyroid follicular cells (thyroid steatosis, TS). In this study, we investigated the morphological and functional changes in thyroid glands of obese humans and animal models, diet-induced obese (DIO), ob/ob, and db/db mice. Expanded IFA depot and TS were observed in obese patients. Furthermore, DIO mice showed increased expression of lipogenesis-regulation genes, such as sterol regulatory element binding protein 1 (SREBP-1), peroxisome proliferator-activated receptor γ (PPARγ), acetyl coenzyme A carboxylase (ACC), and fatty acid synthetase (FASN) in the thyroid gland. Steatosis and ultrastructural changes, including distension of the endoplasmic reticulum (ER) and mitochondrial distortion in thyroid follicular cells, were uniformly observed in DIO mice and genetically obese mouse models, ob/ob and db/db mice. Obese mice displayed a variable degree of primary thyroid hypofunction, which was not corrected by PPARγ agonist administration. We propose that systemically increased adiposity is associated with characteristic IFA depots and TS and may cause or influence the development of primary thyroid failure.</P>
Joung Kyong Lee(이종경),Sei Hyung Yoon(윤세형),Young Cheol Lim(임영철),Hee Chung Ji(지희정),Ki Young Kim(김기용),Gi Jun Choi(최기준),Won Ho Kim(김원호),Jong Geun Kim(김종근),Hyung Soo Park(박형수),L. L. Tandang(탄당),Sung Seo(서성) 한국초지조사료학회 2008 한국초지조사료학회지 Vol.28 No.3
2005년 4월 4일부터 6일까지 강원도 양양군에 대형산불이 발생하여 산림 250 ㏊를 포함하여 인근 농가의 목초지가 피해를 입었다. 따라서 본 연구는 산불 피해 초지에서 보파시기와 보파량이 초지의 생산성과 사료가치에 미치는 영향을 구명하기 위하여 수행되었다. 처리는 대조구, 산불발생 10일후에 추천 파종량의 30%와 50%, 20일후에 30%와 50% 보파를 포함하여 6처리를 공시하였다. 그러나 본 연구에서 산불 피해 목초지에서 생산성과 사료가치에 미치는 보파의 효과는 뚜렷하게 나타나지 않았다. On April 4 to 6, 2005, there was a huge fire in Yangyang-gun, Kangwon-do, Korea, which burned over 250㏊ of forests and 246 buildings including 160 houses. The effects of reseeding rate and timing on productivity and nutritive value of forages in the forest fire burnt pasture in this study were investigated. The effect of reseeding could not be seen in the burnt pastures in terms of forage productivity and quality in short term but there was a long-term effect particularly with higher reseeding rates at later days after the fire on forage botanical composition. We concluded that forest fire brought reduction in pasture forage yield for a short period but it did not make a significant effect for a long term.
Analysis of Whole Crop Barley Silage for Forage Quality Contest in Korea
Joung Kyong Lee,Jong Duk Kim,Hyun Jin Lee,Kyeong Hup Jeon,Jong Guen Kim,Sung Seo,Min Woong Jung,Jin Hyuk Choi,Nam Chul Jo,Hyung Soo Park,Won Ho Kim,Young Chul Lim 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08
Although whole crop barley are now widely grown as a silage crop in Korea, but silage quality of the whole crop barley produced from farmer's fields have not been published. Therefore, this experiment was conducted to evaluate forage quality of whole crop barley which was participated in Korean quality contest in 2008. These data were classified by region, forage production, added inoculants, planting date and harvest date. Difference on lactic acid of barley silage was detected in the region (p<0.05), however, there no significant differences in other chemical composition. The moisture and lactic acid were significant differences in dry matter yield of barley silage. There is all the difference between silage added inoculants and control. Differences between planting dates in ash and crude protein (CP) were detected in barley silage (p<0.05). From comparison within harvest date, lactic acid ㏊d significant differences among barley silage. Differences in forage quality were observed among whole crop barley for silage. Therefore, nutritional quality as well as lactic acid is important in silage quality contest of whole crop barley.
Case Reports : A Case of Granular Cell Tumor of the Trachea
Mi Kyong Joung,Yu Jin Lee,Chae Uk Chung,Jeong Eun Lee,Sung Soo Jung,Sun Young Kim,Ju Ock Kim 대한내과학회 2007 The Korean Journal of Internal Medicine Vol.22 No.2
A 20-year-old man presented to our outpatient clinic with hemoptysis, cough, and pleuritic chest pain. His chest radiograph and pulmonary function tests (PFT) were normal. A bronchoscopy showed a small yellowish patch with a regular surface. A direct bronchoscopic biopsy was performed. The pathologic findings showed a benign granular cell tumor. The respiratory symptoms resolved after biopsying the tumor. On follow-up, there were no signs of recurrence of the granular cell tumor after a period of 24 months.
이종경(Joung Kyong Lee),데이빗 브랜스비(David Bransby) 한국초지조사료학회 2008 한국초지조사료학회지 Vol.28 No.2
Demand for alternatives to petroleum is increasing the production of biofuels from food crops such as corn, soybeans, sorghum and sugarcane, etc. At least for the next 5 years, ethanol demand will be increased greatly in the United States and in the world. Presently, most ethanol produced in the United States is corn (Zea mays) ethanol. As a result, especially in the Americas and Southeast Asia, agricultural land is diverted to biofuel production. Even though biofuel industry has many advantage including national security, economical, energetical and sustainable impacts, it is driving grain prices up and creating considerable concern about the potential negative impacts on a wide range of food products that depend on grain : chicken, pork, beef, and dairy products such as milk, cheese, yoghurt, cream and ice cream. Feedstock crops are crops such as switchgrass (Panicum virgatum, L.), corn stover and grasses that can be used in industrial processes such as fermentation into alcohol fuels. Feedstock is no compete with food. Furthermore it is friendly environmental bioenergy crops. In Korea, with increasing demand for fossil fuels the exploration of alternative sources of liquid fuel is inevitable. I suggest Korea need to research and to develop actively on feedstock for biofuel production through this review.
Alfalfa 파종시 질소와 석회시용이 토양특성 , 잡초발생 , 사초수량 및 사료가치에 미치는 영향
이종경(Joung Kyong Lee),서성(Sung Seo),임윤환(Youn Whan Lim),박광진(Kwang Jin Park) 한국축산학회 1990 한국축산학회지 Vol.32 No.10
This experiment was carried out to determine the effects of nitrogen (0 and 80kg ha^-1) and lime application (0, 2 and 4 t ha^-1) at the seeding time on the soil properties, weeds development, dry matter(DM) yield and nutritive value in alfalfa(Medicago satiua L.) meadow, 1988 to 1989. Soil pH and nutrients on 6 months after adjustment with lime was increased with increasing level of lime. Percentage of weeds was decreased with increasing of N fertilization and lime application. Higher DM production and crude protein yield(CPY) of alfalfa were observed by N fertilization at the seeding time. Also the DM production, CPY, and is vitro digestible dry matter were increased significantly with higher lime application(p $lt;0.05). Based on the results, it is suggested that enough lime application at seeding time of alfalfa are more effective for forage production and nutritive value. Also N fetilization is desirable for alfalfa growth.