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( Bernardino Roca ),( Raquel Monferrer ),( Jose A Ferrero ),( Manuel Roca ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Objective: To find factors associated with increased homocysteine serum level in HIV-infected patients. Methods: Cross-sectional study, carried out as a supplementary task to the usual follow- up of HIV-infected patients. The possible association of increased homocysteine serum level with blood analyses results was assessed with a multiple linear regression analysis. Results: A total of 145 patients were included. Creatinine was higher than normal in 7 patients (5 %), prothrombin time was higher than normal in 36 patients (25 %), and a monoclonal gammopathy was detected in 2 patients (1 %). An association was found between high homocysteine serum level and the following variables: high creatinine (P < 0.001), low folic acid (P < 0.001), and low prothrombin time (P = 0.007). Conclusion: An associations was found between high homocysteine serum level and low prothrombin time.