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원발성 두개골내 수막종 : 1예 보고 A Case Report
김대호,홍현숙,조준희,박재성,박성진,차장규,백상현,이혜경 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Primary intraosseous meningioma of skull is rare, and often confused with a primary bone tumor. We report a case of a 71 years old female patient with an intraosseous calvarial meningioma of frontal bone presenting as a solitary osteolytic skull lesion. Plain skull radiograph, CT and MR images show sharply marginated expansile bony lesion in frontal skull vault, and a small well enhanced soft tissue mass within bone. The mass is extracranially protruded to scalp, and is partially attached to the underlying dura. Outer and inner table of skull vault is slightly bulged out, suggesting intradiploic origin of the tumor. The tumor was treated with surgical excision and cranioplasty. Histological examination revealed fibrous meningioma.
홍현숙,김대호,이혜경,박재성,박성진,조준희,차장규,백상현 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
We report seizure induced brain swelling in three patients. MRI revealed a cortical, subcortical(3/3), and basal ganglia(2/3) high signal intensity on T2- weighted and FLAIR images. The lesion shows low signal on T1-weighted image, and enhanced after contrast administration. Follow up study after 27 days in one case revealed complete resolution of the lesion. The reversible MRI findings may be the results of a local brain swelling, breakdown of blood-brain permeability, and a defect of cerebral autoregulation during seizure activity. The transient nature of such findings have to be considered in the differential diagnosis such as reversible ischemia, migraine, inflammation and infection.
CT 유도하의 경피적 폐생검 : 임상적 의의 및 합병증에 관한 연구 A Study of Clinical Significance and Complication
박재성,백상현,차장규,홍현숙,김대호,박성진,조준희,임한혁,이혜경 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2
Purpose : To determine the diagnostic accuracy and predicting factor of pneumothorax on CT-guided percutaneous transthoracic needle biopsy. Materials and Methods : Using automated biopsy devices, 107 CT-guided percutaneous needle biopsies of pulmonary lesions were performed. Final diagnosis was made with operation or other methods. We retrospectively analyzed the frequency of complications and diagnostic yields of 107 biopsies. The clinical features, treatment, and courses of complications were reviewed, and risk factors of pneumothorax such as depth and size of lesion, CT emphysema score of whole lung and pathway of needle, and the result of pulmonary function test were analyzed. Result : 96 biopsies(89.7%) yielded sufficient tissue for pathologic evaluation. For cases of malignant and benign disease, sensitivity was 91.5% and 87.5% respectively; the corresponding figures for diagnostic accuracy were 88.1% and 77.1%. So, sensitivity and diagnostic accuracy of percutaneous transthoracic needle biopsy was 89.7% and 83.2%. Eighteen(16.8%) of 107 patients developed pneumothorax and 3 of these required application of chest tube or percutaneous catheter drainage. In the group with pneumonthorax, the lesion was significantly smaller(p=0.029) and higher CT emphysema score of pathway of needle(p=0.032). But there were no significant difference between two groups(with or without pneumothorax) for depth of lesion, pulmonary function test(% predictive value of FEV1 and FEV1/FVC) and CT emphysema score of whole lung. Conclusion : CT-guided transthoracic needle biopsy of the pulmonary lesions is safe and easy method of obtaining specimens of good quality and quantity. It may be an useful procedure in the diagnosis of localized pulmonary lesions. For the prediction of pneumothorax, size of lesion and CT emphysema score of pathway of a needle are significant risk factors.
백상현,박재성,차장규,홍현숙,김대호,박성진,조준희,이혜경,최진수 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2
Purpose: BOOP and NSIP also share similar clinical features such as subacute flu-like illness, the finding of bronchoalveolar lavage, the result of pulmonary function test and more favourable outcome than usual interstitial pneumonia(UIP). The author try to compare the HRCT findings of NSIP with BOOP by pattern and distribution of diseases. Materials and Methods: HRCT findings of histopathologically proven NSIP(Group Ⅰ; 6, Group Ⅱ; 7, Group Ⅲ; 2) in 15 patients(5 male, 10 female, age range, 39-69 years; mean age, 53 years), BOOP in 15 patients(6 male, 9 female, age range, 26-76 years; mean age, 52 years) were reviewed retrospectively. Results: The common pattern of the two diseases was admixed consolidation, ground glass attenuation & reticular densities with/without architectural distortion(NSIP; 53.3%, BOOP; 46.7%). The main component of the pattern wan predominantly consolidation(NSIP; 46.7%, BOOP; 73.3%) and ground glass attenuation(NSIP; 40.0%, BOOP;20.0%). Architectural distotion was more provinent finding with NSIP(mild ; 3, moderate ; 4, severe; 2) compared with BOOP(mild; 7, moderate; 2, severe; 0). The predominant overall distribution was lower lung, peribronchovascular & peripheral lung field in both of the two entities(NSIP;73.3%, BOOP; 73.3%). Peribronchovascular involvement was more common with NSIP(100%) than BOOP(80%), whereas peripheral involvement was more common with BOOP(93.3%) than NSIP(80%). Conclusion: The HRCT findings of NSIP and BOOP were similar in pattern and distribution. But NIP manifested more frequently ground-glass attenuation, whereas BOOP showed more frequently consolidation. Architectural distortion was more severe with NSIP than BOOP. NSIP invoved more frequently peribronchovascular space and BOOP were more common in peripheral lung field.
Unusual Presentation of The Popliteal Venous Aneurysm : A Case Report 증례보고
Joh, Joon-Hee,Park, Jai-Soung,Paik, Sang-Hyun,Cha, Jang-Gyu,Park, Seong-Jin,Hong, Hyun-Sook,Kim, Dae-Ho,Lee, Hae-Kyung 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Primary venous aneurysm (PVA) is a rare condition and in most cases of little clinical significance, whereas PVA's are potentially life threatening because they have been recognized to be a source of recurrent pulmonary embolism. Recently, we experienced a case of PVA without obvious pulmonary embolism that was managed by surgery. And we report rediologic findings of the venography, Magnetic Resonance Imaging (MRI) and operation.
Characterization of Yersinia ruckeri isolated from the farm-cultured eel Anguilla japonica in Korea
Joh, Seong Joon,Kweon, Chang Hee,Kim, Min Jeong,Kang, Min Su,Jang, Hwan,Kwon, Jun Hun The Korean Society of Veterinary Science 2010 大韓獸醫學會誌 Vol.50 No.1
Yersinia (Y.) ruckeri has been recognized as a serious bacterial pathogen to several kinds of fish, including rainbow trout. However, there are no reports about the characteristics and pathogenicity of Y. ruckeri isolated from farm-cultured eels. In this study, we isolated and characterized Y. ruckeri from the farm-cultured eel Anguilla japonica in Korea. We investigated the phenotypic and genotypic characteristics of Y. ruckeri and tested the virulence of Y. ruckeri isolates on experimentally infected eels. Examination of the flagellar morphology of Y. ruckeri by electron microscopy showed peritrichous flagella in its cell body. Biochemical reaction studies showed overall identical profiles between the isolates and the reference strain of Y. ruckeri in API 20E and API ZYM tests. We sequenced the 16S rRNA of the Y. ruckeri (1,505 bp) for the genotypic characterization (National Center for Biotechnology Information accession number EU401667). Comparison of the 16S rRNA sequences with previously reported Y. ruckeri strains revealed similar phylogenetic relationships. In the virulence assay of the Y. ruckeri on eels, the eels exhibited listlessness, but Y. ruckeri was reisolated from those of the gills and kidneys.
충주댐 유역의 유출량에 대한 SWAT 모형의 예측 불확실성 분석 기법 비교
조형경,박종윤,장철희,김성준,Joh, Hyung-Kyung,Park, Jong-Yoon,Jang, Cheol-Hee,Kim, Seong-Joon 한국수자원학회 2012 한국수자원학회논문집 Vol.45 No.9
SWAT(Soil and Water Assessment Tool) 모형의 적용성 검증을 위해서는 매개변수 민감도 분석 및 검 보정, 예측 불확실성 분석을 필요로 한다. 최근 SWAT 모형의 불확실성을 분석하기 위한 다양한 기법들이 개발되었는데, 본 연구는 충주댐 유역(6,581.1 $km^2$)을대상으로유역출구점의 실측 일 유출량자료(1998~2003)를 바탕으로 SWAT 모형의 유출관련 매개변수에 대한 불확실성 분석을 실시하였다. 이때 사용된 분석 기법으로는 SUFI2 (Sequential Uncertainty FItting algorithm ver.2), GLUE(Generalized Likelihood Uncertainty Estimation), ParaSol (Parameter Solution) 등을 적용하였다. 이러한 기법은 모두 SWAT-CUP (SWAT-Calibration Uncertainty Program; Abbaspour et al., 2007) 모형에 탑재되어있으며, 모형의 결과로써 검 보정, 매개변수의 민감도 분석, 각종 목적 함수 및 불확실성의 범위 등이 자동으로 산출되므로 모형의 사용자가 불확실성 평가 기법의 분석 및 비교를 손쉽게 할 수 있다. 그 결과 대표적인 목적 함수인 결정 계수($R^2$; Legates and McCabe, 1999)와 NS (Nash and Sutcliffe, 1970) 모형효율은 모두 0.67에서 0.92 사이의 값을 나타내어 대체적으로 모의가 잘 이루어졌음을 알 수 있었다. 그러나 불확실성의 범위를 나타내는 지표인 p-factor 및 r-factor에서는 평가 기법 별로 그 차이가 확연하게 드러났다. 여기서 p-factor는 불확실성 범위에 실측치가 포함되는 비율이며, r-factor는 불확실성의 상대적인 범위로 각각 1과 0에 가까울수록 모의기법의 성능이 우수함을 의미한다. 세가지 알고리듬 중에서 SUFI2의 p-factor가 약 0.79로 가장 높게 나타났으며, ParaSol의 r-factor가 0.03으로 가장 작게 나타났다. 본 연구의 결과는 SWAT 모형을 이용한 수문 모의에서 수문분석에 따른 예측결과의 불확실성을 정량적으로 평가함으로서, 모형의 적용성 평가 및 모의결과의 신뢰성 확보에 근거자료로 활용이 가능할 것으로 판단된다. To fulfill applicability of Soil and Water Assessment Tool (SWAT) model, it is important that this model passes through a careful calibration and uncertainty analysis. In recent years, many researchers have come up with various uncertainty analysis techniques for SWAT model. To determine the differences and similarities of typical techniques, we applied three uncertainty analysis procedures to Chungju Dam watershed (6,581.1 $km^2$) of South Korea included in SWAT-Calibration Uncertainty Program (SWAT-CUP): Sequential Uncertainty FItting algorithm ver.2 (SUFI2), Generalized Likelihood Uncertainty Estimation (GLUE), Parameter Solution (ParaSol). As a result, there was no significant difference in the objective function values between SUFI2 and GLUE algorithms. However, ParaSol algorithm shows the worst objective functions, and considerable divergence was also showed in 95PPU bands with each other. The p-factor and r-factor appeared from 0.02 to 0.79 and 0.03 to 0.52 differences in streamflow respectively. In general, the ParaSol algorithm showed the lowest p-factor and r-factor, SUFI2 algorithm was the highest in the p-factor and r-factor. Therefore, in the SWAT model calibration and uncertainty analysis of the automatic methods, we suggest the calibration methods considering p-factor and r-factor. The p-factor means the percentage of observations covered by 95PPU (95 Percent Prediction Uncertainty) band, and r-factor is the average thickness of the 95PPU band.