악성흑색종과 양성멜라닌세포성모반에서 bcl-2 단백발현에 관한 면역조직화학적 연구

이성열,이종석,김현조,정현,조현듯,김의한 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background: The bcl-2 protein, contrast to p53, has been shown to be suppress the apoptosis, and overexpression of the bcl-2 protein has been reported in several malignant tumors. Although how the bcl-2 protein takes part in tumorigenesis has not been proved, the bcl-2 positive tumors appeared to have good prognosis in some malignant tumors. The expression pattern of the bcl-2 in melanocytic nevi and malignant melanoma have not been well known. The authors analyzed immunohistochemically expression of the bcl-2 protein to investigate the role of the bcl-2 protein in developing malignant melanoma. Method: 10 malignant melanoma and 10 benign melanocytic nevi were immunostained with anti-bcl-2 monoclonal antibody. Results: In malignant melanoma, 1 case was 2+ positive, 9 cases were 3+ positive. In benign melanocytic nevi, 2 cases were 2+ positive, 8 cases were 3+ positive. Conclusion: Bcl-2 protein is expressed by benign melanocytic nevi and malignant melanoma. There is no difference of bcl-2 protein expression in melanocytic nevi and malignant melanoma.

전자결제시스템으로서의 CHIPS와 Fedwire에 관한 비교 연구

이병렬,김종칠 신라대학교 경제경영연구소 2007 경제경영연구 Vol.8 No.-

This article is to discuss on comparative research between CHIPS and Fedwire as the cross-border payment systems which America have used at present. The CHIPS is a New York-based automated private-sector clearing facility for large-dollar transfers. It is a central switch communication and settlement system whose 53 participating banks exchange same-day payment messages over dedicated communication lines linking each one to the CHIPS central computer. On January 22, 2001, the CHIPS introduced immediate finality for payment released from the CHIPS queue. Unlike the Fedwire system, the CHIPS system is not a real-time gross settlement system. The CHIPS is hybrid system that uses a computer program to select payment order in a queue for release to the receiving bank. The CHIPS are governed by CHIPS Rules and Administrative Procedures. The Fedwire system is a nationwide electronic fund-transfer system facilitating same-day transfers throughout the United States. It is a gross settlement system providing immediate credit to the receiving bank's master account. Communicating between a Federal Reserve Bank and Fedwire users can be either on-line or off-line. The Fedwire transfers are governed by Subpart B of Regulation J, issued by the Federal Reserve Board, which incorporates U.C.C. Article 4A but preempts or supersedes any of its inconsistent provisions.

점화에너지 방전특성이 희박연소한계에 미치는 영향

이중순,하종률,이종숭 東亞大學校 大學院 1998 大學院論文集 Vol.23 No.-

The purpose of this research is to clarify that ignition characteristics such as ignition energy and discharge pattern have effect upon maximum pressure, maximum pressure appearance timing. IMEP and revolution of engine on the lean burn of mixture. In this paper, We studied relations between discharge performance of ignition energy and extension of lean inflammability by development of High Frequency Ignition System.

아토피 피부염 환자에서 혈청내 Cu와 Zn치 및 Cu/Zn비에 관한 연구

이성열,정현,이종석,황규왕 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

아연과 구리는 피부를 포함하는 인체의 거의 모든 기관에서 일어나는 대사과정에 작용하는 metallonenzyme의 보조인자로 상당히 중요한 역할을 수행한다. 저자들은 정상대조군 10명, 전신성 아토피성 피부염 환자 16명을 대상으로 atomic absorption spectrometry를 사용하여 혈청 아연과 구리치를 측정하였고 그결과로 혈청 구리/아연 비를 구하였다. 그 결과 혈청 구리치는 대조군에 비하여 아토피성피부염 환자에서 통계적으로 의의있게 높게 나타났다. 이는 아마도 아토피성 피부염에 의한 염증반응으로 이차적으로 ceruloplasmin이 증가되어 나타난 것으로 생각되나 이 것이 명확히 규명된 것은 아니다. 혈청 아연치는 약간 감소하였으나 통계적인 유의성은 없었고 혈청 구리/아연 비의 값은 약간 증가되었으나 역시 통계적 유의성을 찾을 수는 없었다.

인체 두피 모낭 외측모근초 각질형성 세포의 배양

이종석,이성열,박영립,서용원,황규왕 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

Follicular stem cell was assumed as a hair matrix cell. But, recently it was suggested that follicular stem cells were in the bulge portion of outer root sheath of hair follicles, and its proofs were reported. We tried to culture outer root sheath keratinocytes in the bulge portion of human hair follicles, and it would be experimental base for many factors and drugs realated with hair growth and differentiation. The outer root sheath keratinocytes were isolated from plucked human hair follicles, and could be serially passaged for up to 2 times on used biologic feeder cell layer.

유방외 Paget 병 1예

이성열,이종석 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Extramammary Paget's disease is a rare cutaneous adenocarcinoma, usually of epidermal origin and glandular differentiation and frequently associated with and underlying adnexal carcinoma and perhaps with underlying internal malignancy. We report a case of extramammary Paget's disease on the right scrotum and penile shaft.

원형 탈모증 환자의 혈청 철분 조사

이종석,정현,이성열 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

Alopecia areata is characterized by rapid and complete loss of hair in one, or more often several, round or oval patches, usually on the scalp. It is not at present possible to attriute all or indeed any case of alopecia areata to a single cause. Among the many factors which appear to be implicated in at least a proportion of cases are the patient's genetic constitution, the atopic state, non-specific immune and organ-specific autoimmune reactions and possibly emotional stress. Iron deficiency as an etiological factor in diffuse alopecia and androgen-dependent alopecia has been discussed previously. We decided to investigate the iron status of alopecia areata patients visiting our department for treatment. All these patients had alopecia areata for at least 6 months before visiting our department. Thirty patients(16 female and 14 male) participated in the study. Blood samples were sent for full blood count, including estimation of mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, Fe, TIBC, and serum ferritin. The results are shown in Table. We suggest that serum ferritin assay should be included in the hematological assessment of patients with alopecia areata.

내연기관용 점화장치의 방전에너지특성에 관한 연구

이중순,배종용,이태원,하종률 동아대학교 공과대학 부설 한국자원개발연구소 1994 硏究報告 Vol.18 No.1

Ignition devices used in electric ignition engine supply electric sparks with the air-fuel mixture intake into the cylinder and compressed, at the optimal time and enable the mixture to ignite and explode. It is critical, therefore, that the ignition energy be changed into more inflammable type, identifying constructions of the ignition energy and factors affecting on the inflammation by the energy. In order to accomplish this, CDI, SIS and MIS based upon the DLI system, in which high level ignition energy is supplied for the ignition plug directly from the ignition coil, have been developed and manufactured.

수종의 표피종양에서 p53단백발현에 관한 면역조직화학적 연구

이성열,부태성,이종석,김의한 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

This study was carried out to evaluate the aberrant expression of P 53 protein using immunohistochemical method in 28 basal cell carcinoma, 24 squamous cell carcinoma, 7 keratoacanthoma, and 4 Bowen's disease. Eighteen out of 28(64.3%) and twenty one out of 24(87.5%) showed positive reaction in the nucleus of basal cell carcinoma and squamous cell carcinoma, respectively. Five out of 7(71.4%) and three out of 4(75%) showed positive reaction in the nucleus of keratoacanthoma and Bowen's disease. In conclusion, our results suggest that the aberrant expression of P53 protein is a common and an important part of the pathogenetic sequence in a majority of cases of epidermal neoplasms.

색소성 양진 1예

이성열,이종석 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

prurigo pigmentosa is a chronic pruritic inflammatory dermatosis characterized by erythematous papules in a reticalated pattern that resolve leaving a reticulated, mottled hyperpigmentation. Most cases have been reported from Japan. We report a case of prurigo pigmentosa in a Korean man of 19 years of age.