체내 카드뮴 농도에 따른 신세뇨관 미세손상 유병률

임동혁, 문선인, 엄상용, 김용대, 강종원, 김헌 충북대학교 의과대학 충북대학교 의학연구소 2011 忠北醫大學術誌 Vol.21 No.2

-본문참고-

DC/DC 승압 컨버터의 출력 특성 개선을 위한 스너버 회로 설계

김성종,김인혁,정구종,손영익,한병문 明知大學校 産業技術硏究所 2009 産業技術硏究所論文集 Vol.28 No.-

Applications of DC!DC boost converters are increasing recently in many industrial areas including renewable energy sources. High switching frequency of the power semiconductor devices including MOSFET, IGBT causes the EMI noise owing to the large values of dv/dt and di/dt. Since the EMI noises degrade power efficiency and reliability of the system many researches have been made to reduce the noise. This paper presents a passive snubber circuit to improve the tum-on and turn-off transients of the pulsewidth modulated (PWM) DC/DC boost converters. The noises in the output voltage of the DC!DC converter are reduced by adding a resistor and an inductor to the circuit. Experimental results show the effectiveness of the proposed snubber circuit to improve the output characteristics of the boost converter.

變煥法에 의한 設計渴水量의 誘導

李淳赫,朴鐘國,孟昇辰 충북대학교 농업과학기술연구소 1994 農業科學硏究 Vol.11 No.2

Derivation of reasonable design low flows was attempted by comparative analysis of design low flows derived by Power and SMEMAX transformations for the normalization of skewed distribution in the four watershed of main river basins in Korea. The results were analyzed and summarized as follows. 1. Basic statistics of annual low flows for the selected watersheds were calculated by using Power and SMEMAX transformations. 2. Power transformation has found to be the best for the normalization of skewed distribution among others including Log, Squareroot and SMEMAX transformations. 3. Design low flows for the seleted watershed were derived by the Power and SMEMAX transformations. 4. Judging by the relative suitablities for the Power and SMEMAX transformations, it was found that design low flows using two methods are closer to the observed data within 10 years of the return period, and those of Power transformation can be acknowledged as a reasonable one in comparison with SMEMAX transformation over 10 years of the return period.

목제품만들기 단원의 수행평가를 위한 포트폴리오 자료 개발

이종오,이상혁 韓國實科敎育硏究學會 1999 實科敎育硏究 Vol.5 No.2

The purpose of this study was to develop and identify the effects of portfolio materials for performance assessment on the unit of wooden ware making practical arts in the primary school. In this study, the researcher was analyzed the literatures which was related to portfolios, and created the elements and items of performance assessment, and developed portfolio materials. The results of the study were as follows: (1) After the portfolio materials of practical arts applied to lesson of the woodenware making unit, the results of learning achievement test showed a level by averages 80.8%. The portfolio materials improved the efficiency of performance assessment, and effected on the increasing performance ability in practical arts. (2) After using portfolios, in the results of the learning attitude test of students, seven items of affective domain consist of pleasure during the practical arts education, value of nature, attitude of using tools safely, feeling of satisfaction in the result of practices, confidence in the working of wood-working tools, continuous practice of the practical exercise, attitude of make and using goods of life, which used portfolio materials effected on the increasing learning achievement level.

기관골 신생증 1예

오영상,이은우,정종혁,문승원,김수현,김동한,양혁승,박정환,박경옥,강성수,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Tracheobronchopathia osteoplastica is a rare disorder of unknown cause characterized by the projection of numerous bony or cartilaginous submucosal nodules into the tracheobronchial lumen with sparing of the posterior membranous portion of tracheobronchial tree. In the past, most of the cases were diagnosed as secondary finding at autopsy. Nowaday, the key component of the evaluation is flexible fiberoptic laryngoscopy and bronchoscopy, which typically demonstrates irregular spicules of subrnucosal bone and cartilage projecting into the tracheobronchial lumen and causing various degrees of airway obstruction. A 45 years old man was visited Sunchon St. Carollo hospital due to discomfort on throat. We saw several nodules just below vocal cord via laryngoscope. The computed tomography revealed multiple small calcified nqdules on trachea and both main bronchi. Pathologic finding of bronchoscopic biopsy showed abnormal proliferation of bony and cartilagious nodules in the tracheal submucosa. These fingdings were consistent with tracheobronchopathia osteoplastica. We report here on a case of tracheobronchopathia osteoplastica with review of literature.

Coating을 시행한 뇌동맥류 파열환자의 예후

박종혁,석종식,목진호,박관,김영백,민병국,황성남,최덕영 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.6

In rare occasions in which aneurysmal neck clipping is nearly impossible, coating is employed. During the period from 1985 to 1992, 312 patients with aneurysm underwent surgery ; aneurysmal neck clipping were performed in 284 cases while coating only in 28. The reasons that coating was required were ; wide and broad neck in 13, perforators arising from the neck in 4, neck tearing during dissection in 3, very friable neck in 2, severe adhesion with surrounding structures in 3, and small aneurysm without enough room for clipping in 3. In twenty-three cases, cotton wisp and bioglue were used as coating materials. In another five cases, the aneurysmal wall was reinforced using Surgicel or Gelfoam. Patients were followed for 24 months on average of all the patients. Four had last contact Six died(4 due to rebleeding and 2 due to pneumonia). Fourteen were good and 4 were moderately disabled. There were no rebleeding incidences during first three months' follow-up after coating. We thus concluded that coating an aneurysm offers some protection from rebleeding, particularly when the rebleeding risk period is over.

파쇄골 이식술을 이용한 안정된 무시멘트 비구컵 주위의 골융해에 대한 치료

서유성,임강철,권혁룡,임수재,박종석,이병일 대한고관절학회 2003 Hip and Pelvis Vol.15 No.3

마늘成分이 肝 Glutathione S-Transferase 및 Glutathione peroxidase 活性에 미치는 影響

朴鍾珉,李相日,金善業,許瑾,金碩煥,徐赫珪 嶺南大學校 環境問題硏究所 1985 環境硏究 Vol.5 No.2

Garlic (Allium sativum L.) is a widely distributed plant used in all parts of the world not only as a spice but also as a popular remedy for several thousand years Recent studies have shown that garlic components may regulate the many metabolism in liver. Therefore, the present work was undertaken to study the effect of garlicjuice, allicin fraction and heat-treated allicin fraction on the hepatic glutathione s-transferase and glutathione peroxidase which protect against toxic compound and lipid peroxide in liver. The results obtained were summarized as follows. By the treatment of garlic juice, glutathione s-transferase and glutathione peroxidase activity was increased in hepatic cytosolic fraction compare with control group. The enzyme activtiy is more increased by treatment with boiled garlic juice compared with fresh garlic juice in rats. The effect of allicin fraction and heat-treated allicin fraction on the hepatic glutathione s-transferase was observed that these components inhibited the enzyme activity in vitro, whereas the enzyme activity was strongly inhibited heat-treated allicin fraction than allicin fraction. These observation led us to conclude that the garlic components which are a stable substance in heat may regulate the hepatic glutathione s-transferase and glutathione peroxidase activity.

복합 적층 박판의 열응력 파손에 대한 진동 활용 비파괴평가

이성혁,이정기,최낙삼 韓國非破壞檢査學會 1999 한국비파괴검사학회지 Vol.19 No.5

두께 1mm의 얇은 복합적층판의 자유경계단부에서 열응력으로 인해 발생하는 미세손상을 진동거동과 관련된 비파괴평가의 가능성을 연구하였다. 유한요소 열응력해석을 통해 예상되는 손상발생영역을 초음파 C-스캔과 광학현미경을 이용하여 관찰하였다. 사인 스윕시험을 이용한 적층보 시험편의 횡진동 해석결과, 미세한 내부손상으로 인해 고유주파수가 확실히 감소하였으며 감쇠비도 상당히 증가하였다. 길이가 짧은 적층보 시험편과 2차 모드의 공진주파수를 이용하여 얇은 적층판에서 열응력으로 유기된 미세손상을 매우 민감하게 평가할 수 있음을 알았다. A feasibility investigation on vibration-based nondestructive evaluation of thermal stress-induced micro failure in the free edge region of thin composite laminates(1mm thick) has been carried out. The failure occurrence and damage zone, which were predicted by the three-dimensional finite-element thermal stress analysis, were observed using the ultrasonic C-scan and optical microscopy. Analysis of the vibration spectrum measured from the laminate beam specimens by the vibration sweep test exhibited that the obvious decrease in resonancy frequency and some considerable increase in damping factor were associated with the micro-failure formation. The vibration technique utilizing short beam and high resonant frequency was found to be very sensitive to the thermal stress-induced damage in the thin laminates.

티로파 정(염산티로프라미드 100 mg) 에 대한 안티모딕정의 생물학적 동등성

곽손혁,구선회,린팜두안,강종성,황성주 충남대학교 약학대학 의약품개발연구소 2000 藥學論文集 Vol.16 No.-

Bioequivalence of two tiropramide tablets, test drug (Antimodic® tablet: Chong Kun Dang Pharm. Co.) and reference drug (Tiropa® tablet: Dae Woong Pharm. Co.), was evaluated according to the guidelines of Korea Food and Drug Administration (KFDA). Twenty healthy male volunteers were divided randomly into two groups and administered the drug orally at the dose of 100 mg as tiropramide hydrochloride in a 2×2 crossover study. There was a week washout period between administrations. Blood samples were taken at predetermined time intervals for 10 hr and the plasma concentration of tiropramide HCl was determined by a GC/MS method. AUC_0-10hr (area under the plasma concentration-time curve from time zero to 10 hr), C_max (maximum plasma drug concentration) and T_max (time to reach C_max) were estimated from the plasma drug concentration-time data. Analysis of variance (ANOVA) revealed no difference in AUC_(0-10hr), C_max and T_max between two products. The apparent differences of these parameters between two products were less than 20% (i.e., 0.043, 6.430 and 8.929% for AUC_(0-10hr), C_max and T_max, respectively). The powers (1-β) for AUC_(0-10hr) and C_max were over 0.9. Minimal detectable differences (Δ) at α=0.05, 1-β=0.8 were less than 20% (i.e. 15.71 and 12.53% for AUC_(0-10hr) and C_max, respectively). The 90% confidence intervals (δ) for these parameters were also within ±20% (i.e. -9.15≤δ≤9.24 and -0.90≤δ≤13.77 for AUC_(0-10hr) and C_max, respectively). These results satisfied the criteria of KFDA guidelines for bioequivalence, indicating the two tablets of tiropramide were bioequivalent.