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Effects of Test Temperature on Low Cycle Fatigue Behaviors in Large Mold Steel
Jong‑Ho Shin,Jehyun Lee 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.7
A mold steel for plastic injection was subjected to low cycle fatigue (LCF) tests at temperatures of 25, 200, and 250 °C. LCFtests were carried out at a total strain amplitude (Δεt/2) from 0.004 to 0.012 under a constant strain rate of 0.01 s–1. Transmissionelectron microscope images showed that cyclic loading accelerated dislocation recovery as the LCF test temperatureincreased. The LCF life increased as a result of improvement in the ductility associated with dislocation recovery as the testtemperature increased. The LCF behavior at the test temperature range followed the Coffin–Manson equation. Empiricalequation was proposed to predict the LCF life of the mold steel within the test temperature range.
Jong‑Ho Shin,Jehyun Lee 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5
Considering the variation of the solid/liquid interface morphology with a growth condition, microstructure selection map inperitectic system was modified by comparing growing α (primary phase) interface tip temperature and β (peritectic phase)nucleation temperature. The results were proved experimentally in hypo-peritectic Sn–Cd alloys by delicate directionalsolidification experiment under the diffusive growth condition using capillary thin tube. When β-phase took over α-phaseand grew a short distance as the leading phase, the instability of β-phase was first observed experimentally. This phenomenawas explained by constitutional undercooling, which was present temporarily in liquid ahead of the β/l interface.
Joo Heon Kim,김경민,Jin Uk Jeong,Jong-Ho Shin,신재민,방기태 대한신장학회 2019 Kidney Research and Clinical Practice Vol.38 No.3
Background: Autophagy is a highly balanced process in which lysosomes remove aged and damaged organelles and cellular proteins. Autophagy is essential to maintain homeostasis in the kidneys. Methods: Using human renal tubule cells HK-2, we assessed the impact of high glucose (HG) on autophagy. We also evaluated the capability of sulforaphane (SFN) to protect the HK-2 cells from HG-induced apoptosis by modulating autophagy. Results: SFN modulated autophagy and decreased apoptosis in the HK-2 cells that were cultured in 250 mM glucose medium for two days. The reactive oxygen species (ROS) levels increased, as expected, in the cells cultured in the 250 mM glucose medium. However, the SFN decreased the ROS levels in the HK-2 cells. The overexpression of heme oxygenase-1 (HO-1) by SFN decreased the expression of LC3 and beclin-1. LC3 and beclin-1 were involved in the downregulation of caspase-3 that was observed in the HG-induced cells. Conclusion: The activation of nuclear factor E2-related factor 2 (Nrf2)-HO-1 inhibited ROS expression and subsequently attenuated autophagy and cell apoptosis after HG injury was decreased. HG injury led to the activation of autophagy and HO-1 in order to combat oxidative stress and protect against cell apoptosis. Therefore, HO-1 activation can prevent ROS development and oxidative stress during HG injury, which considerably decreases autophagy and apoptosis.
신동면,한상연,김종호,이호창,김민용 한국정책학회 2004 韓國政策學會報 Vol.13 No.1
이 논문에서는 정보기술이 지역복지 전달체계의 개편에 기여할 수 있다는 인식을 바탕으로 지역복지 정보네트워크를 구축하기 위한 모델과 지역복지 정보네트워크를 위한 컨텐츠 구성 방안 등에 대하여 논의하고 있다. 정보의 공유와 상호협력 관계를 충실하게 구혈할 수 있는 정보네트워크 구축방식은 지역복지 전달과정에 관련된 공급자, 수혜자, 후원자, 그리고 정부를 포함한 모든 당사자들을 상호 연결하는 e-허브 모델이 바람직하다. 지역복지 네트워크 허브는 지역복지 전달과정에서 각 주체들이 정보네트워크에 올린 원시정보를 분류?축적?갱신함으로써 사회복지서비스의 수급을 연결시키는 역할을 담당하기 때문에 지방자치단체가 운영의 책임을 져야 한다. 지역복지 정보네트워크는 지역복지 전달과정에서 5C 활동-컨텐츠(Contents), 의사소통(Communication), 커뮤너티(Community), 협업(Collaboration), 기여(Contribution) -을 촉진할 것이다. 이중에서 특히 컨텐츠의 수준은 지역복지 정보네트워크가 효과적으로 운영되기 위한 관건이 된다. 이에 본 논문에서는 공급자, 수혜자, 후원자, 그리고 정부가 지역복지 정보네트워크의 운영을 위하여 제공해야 할 컨텐츠를 구체적으로 예시하고 있다. 지역복지 정보네트워크는 5C 활동을 통하여 지역복지 전달과정에서 관련 당사자들 간의 상호, 협력적 관계를 지속시킴으로써 지역복지 전달체계의 효율성, 적절성, 통합성, 전문성, 접근성을 제고하는 데 기여할 것이다.
신태균,김승호,배종희,이두식,임윤규,이수길 濟州大學校 農科大學 動物科學硏究所 1992 動物科學論叢 Vol.7 No.1
Two cases of verminous arteritis were chosen for this case. These horses were originally submitted for necropsy in the Cheju horse race. Case 1 : At necropy, there was increased ascite, thickened ab-dominal aorta at junction of cranial mesenteric artery. In the aorta, there was a long thrombus embed-ded with strongylus vulgaris larvae. Some larvae were also firmly attached in the aortic intima Histologically, there was infiltration of neutropliils, eosinophils, and macrophages in the tunica media. At the junction of thrombus and arterial intima, there was proliferation of vessels. Case 2 : At necropsy, there was thickened abdominal aorta, which showed typical verminous arteritis with thrombus. Histologically, ceseous tissues with haematopoietic tissue was recognized in the aortic wall.
신정호 大韓神經精神醫學會 1978 신경정신의학 Vol.17 No.4
A clinical study was conducted on the psychiatric problems manifested by 21 chronic renal failure patients on maintenance hemodialysis at Yonsei Medical Center. Structred interviews with the patients and family members were done at least twice on each patient and Zung's self-rating depression scale, Hamilton's anxiety and depression scales were administered. The data obtained were compared with those of both normal control and neurotic patients group. The results indiated that patients on the hemodialysis have confronted with serious personal, familial and socioeconomic stresses and they suffered from marked psychiatric symptoms such as depression, pessimistic idea, guilty feeling, psychomotor retardation, rejected feeling, increased dependency, irritability and insomnia. But they showed tendency to minimize or deny their problems and complaints, as reflected in the self-rating depression scale. Denial was considered to be the mian defense mechanism against chronic stress associated with the procedure. And the depression of those patients was characterized by the fact that female patients showed higher scores than males, and by the fact that the longer the duration of hemodialysis, the more severe the degree of depression and that comparing to neurotic patients, they showed higher scores in decreased libido, dissatisfaction and suicidal rumination in Zung's SDS. Also two case histories of acute psychotic episode were presented; they were characterized by relatively short-term progress of about 7 days with good prognosis and bizarre symptoms as mask like dull facial expression and symbolic expression of suicide and of conflit associated with death. Lastly, the possible roles of psychiatry for patients on the hemodialysis were discussed.
대형 화재로 인한 사상자의 손상 유형과 합병증 : 동인천 라이브호프 화재를 중심으로
신중호,김재광,염석란,신종환,민순식,임용수,양혁준,이근,황성연 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3
Background: High risks of fire alway exist for buildings in urban areas, especially those in downtown. Crowds, as well as more complex and larger structures, may cause more victims in the event of fire; therefore, emergency medical service plans must be established for such disastrous events. Methods: On the evening of October 30,1999, a fire broke out in downtown, Dong-Incheon Live-Hof restaurant; 56 people were killed and 76 were injured. Most of them were teenagers. We retrospectively reviewed the medical records of the victims, Results: 1) Among the 56 dead, 54 died from smoke inhalation, one from extensive burns, and one from sepsis during treatment. 2) Among the 76 injured, 70 patients suffered from smoke inhalation, 53 from burns, and 9 from several types of trauma (sprains, contusions, lacerations, abrasions, fractures, etc.). 3) Later complications were laryngeal edema, pulmonary edema, scar contracture, and hypoxic brain damage, and so forth. 4) Post traumatic stress syndrome was unexpectedly more prevalent in mildly to moderately injured survivors and witnesses than in seriously injured survivors. Conclusion: Many complications exist after a fire. Some may be resolved in time, but others may result in permanent sequelae. Early rescue, early triage, and early management during transport by emergency medical service (EMS) personnel can result in fewer complications and a lower mortality rate. Therefore, we propose the establishment of plans to be followed during various major disasters.
HeLa세포 허족의 액틴 미세섬유에 대한 면역 형광현미경적 연구
신길상,김호진,김완종 순천향대학교 기초과학연구소 2000 순천향자연과학연구 논문집 Vol.6 No.1
Actin cytoskeletons of HeLa cell-pseudopodia are observed in confocal laser scanning microscopic field after the treatment with monoclonal anti-actin and anti mouse IgG-FITC. The cytoskeletons are then compared with the control group stained with coomassie blue. The network of actin microfilaments in lamellae and meshwork in leading edge can be observed while stress fiber are observed on ventral surface of the cells which are intimately associated with substrate. The meshworks are fine microfilaments embedded in peripheral pale cytoplasm of the pseudopodium, the networks are composed of rather thick cross linked actin microfilaments in the lamellae in the middle cytoplasm. The thicker stress fibers are often adhered to the inside of ventral undulating cell membrane at the peripheral psuedopodium. These actin filaments are conserved especially in microwave field(microwave fixator KC600A). The features of the microfilaments and suggested functions are discussed.
신종익,이정한,송한범,강대언,오상훈,차승렬,이용재,김상대,이원호 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)
This study investigates the performance of the reinforced concrete frame with the steel plate slit damper. The test was carried out to investigate the structural behavior between the reinforced concrete bare frame and the reinforced concrete frame with the steel plate slit damper. The test results showed that the energy absorption capacity of the damped-frame was several times larger than that of the bare frame. For the damage by the input energy is concentrated on the steel plate slit damper, the ductilities of the former structure were increased and the damaged frame can be reused after exchange the steel plate slit damper.