Conceptual Study for Tissue-Regenerative Biodegradable Magnesium Implant Integrated with Nitric Oxide-Releasing Nanofi bers

Jin‑Kyung Jeon,Hyunseon Seo,Jimin Park,Soo Ji Son,Yeong Rim Kim,Eun Shil Kim,Jong Woong Park,Woong‑Gyo Jung,Hojeong Jeon,Yu‑Chan Kim,Hyun‑Kwang Seok,Jae Ho Shin,Myoung‑Ryul Ok 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.4

The excessive initial corrosion rate of Mg is a critical limitation in the clinical application of biodegradable Mg implantsbecause the device loses its fi xation strength before the fractured bone heals. This study suggests a new approach to overcomethis hurdle by accelerating tissue regeneration instead of delaying the implant biodegradation. As angiogenesis is anessential process in early bone regeneration, a Mg implant coated with electrospun nanofi bers containing nitric oxide (NO),which physiologically promotes angiogenesis, is designed. The integrated device enables adjustable amounts of NO to bestored on the NO donor-conjugated nanofi ber coating, stably delivered, and released to the fractured bone tissue near theimplanted sites. An in vitro corrosion test reveals no adverse eff ect of the released NO on the corrosion behavior of the Mgimplant. Simultaneously, the optimal concentration level of NO released from the implant signifi cantly enhances tube networkformation of human umbilical vein endothelial cells without any cytotoxicity problem. This indicates that angiogenesis canbe accelerated by combining NO-releasing nanofi bers with a Mg implant. With its proven feasibility, the proposed approachcould be a novel solution for the initial stability problem of biodegradable Mg implants, leading to successful bone fi xation.

糞尿와 都市 廢棄物과의 混合處理에 대한 硏究 (Ⅰ) : 肥料化를 中心으로한 實驗室的 考察 Experimental study for the fertilization

金熙鐘,金相烈,金秀生,孫晋彦,金燦國,成周慶,吳英敏 동아대학교 환경문제연구소 1977 硏究報告 Vol.1 No.1

우리나라에 있어서 都市廢棄物의 主인 糞尿와 固形廢棄物의 太宗인 無煙炭재를 同時에 效果的으로 處理할 수 있고 또한 堆肥化시킬 수 있는 好氣性 酸化方式의 最適條件을 얻기 위하여 生糞尿 및 煉炭재의 理化學的 및 生物學的 數値를 測定하고 이를 基礎로하여 上記 兩者를 混合處理 할수 있는 消化條件(溫度, 糞尿와 煉炭재의 配合比, 기타 固形物의 添加量, 注入되는 空氣量의 變化)에 따른 C.O.D., B.O.D.의 變化, 水分 및 電氣傳導度의 變化, 熱灼減量, N量의 變化 等을 硏究하였으며 이들 사이의 相關關係를 檢討하여 다음과 같은 結論을 얻었다. 1. 生糞尿에 固形廢棄物인 煉炭재나 紙類를 配合시켜 消化시키므로서 케이크속의 질소成分의 量을 增加 시킬수 있다. 2. 煉炭재의 配合은 糞尿의 消化速度를 增加 시킨다. 3. 糞尿의 處理를 위한 反應槽의 溫度는 50℃보다 60℃로 維持 시킬때 消化速度가 크다. 4. 反應槽의 溫度를 一定하게 했을때 空氣의 注入速度는 初期 反應時는 적게하고 後期 反應時는 크게 함이 效果的 이다. For the effective treatment and usable disposal of urban wastes in the area of Busan city, the composition of the nightsoil and anthracite bulky ash which is the main munic ipal solid wastes have been studied on the digestion of the compositive mixtures with the variable conditions that are ratio of compounding between nightsoil and ash, amount of solid additives and volume of air for the effective airation at 50, 65℃. The digestion has been detected by the physico-chemical and biological data; pH, specific gravity, content of moisture, C.O.D., B.O.D., electroconductance of the solution of the results, decrease of nition, and volume of total free nitrogen etc. The results are obtained as follows. 1) The characteristics of domestic nightsoil are different to the foreign data as table 5, but the data of anthracite ash almost are same except the composition of Fe₂O₃ and Al₂O₃. 2) Amount of total free nitrogen are increased by the digestion with the addition of solid waste, as effective absorption, to the nightsoil. 3) The digestion are accelerated by the compounding of ash, but the adding of sulfuric acid to fix the free ammonia reduced reaction. 4) The airation have to proceed slowly at initial step, and then endure enough volume of air at the later step.

지역4-H조직의 내적 적합성에 관한 문화기술적 연구

김진모,김진군,전영욱,이정은,최영창,이은영 한국농업교육학회 2008 농업교육과 인적자원개발 Vol.40 No.2

이 연구의 목적은 지역4-H조직의 내적 적합성을 탐색하고 이를 기술하는데 있었다. 2006년 8월부터 10월까지 약 3개월 동안 지역4-H후원회 회장 및 임원진 3명, 지역4-H연맹 회장 1명, 학교4-H 지도교사 4명, 지역의 영농4-H회장 1명, 시·군 농업기술센터 소장 및 4-H담당자 9명을 주요 연구 참가자로 하여 심층면담을 통해 자료를 수집하였다. 수집한 자료를 분석한 결과는 다음과 같았다. 첫째, 지역4-H조직 관련자들이 인식하는 지역4-H조직의 주요성과 격차로, ① 민간4-H조직을 중심으로 한 자율적이고 독립적인 활동 부재, ② 지역4-H조직 간 다양한 종류의 협력 부재, ③ 지역사회에서 4-H활동에 대한 가치 인식 부족이 나타났다. 둘째, 지역4-H조직의 핵심 과업으로 ① 4-H의 가치 및 이념에 부합하고, 지역의 실정에 맞는 프로그램 확보, ② 지역4-H 조직 간 협력적 네트워크 확립, ③ 4-H에 대한 지역사회의 관심 및 지지 확보가 나타났다. 셋째, 지역4-H조직의 내적 부적합성으로는 ① 인원 확보의 어려움과 핵심과업에 대한 전문성 결여, ② 관료화되고 경직된 낡은 문화, ③ 조직적 자원의 축소 및 조직 간 낮은 네트워크의 수준이 도출되었다. The purpose of this study was to describe and understand internal fit in Local 4-H Organization. The main participants of this study were one leader and two members of Local 4-H Society for the support, one leader of Local 4-H Association, four School 4-H teacher, one leader of Local farm 4-H, 9 local agricultural extension workers. The data were collected through in-depth interview with them from August, 2006 to October, 2006. The Results from this study were as follow: 1. Key performance gaps of local 4-H organizations were identified: ① lack of local 4-H based activities, ② lack of various types of partnership between local 4-H organizations, ③ lack of understanding value of 4-H activities in the communities. 2. Key tasks of local 4-H organizations were identified: ① developing local 4-H programs based on 4-H's values and ideas, ② establishing the cooperative networks among local 4-H organizations, ③ ensuring the interest and support about 4-H in the communities. 3. Internal misalignments of local 4-H organizations were identified: ① difference of recruitment and lack of expertise, ② bureaucratic and rigid cultures, ③ decrease in organizational support and low level of network among organizations.

Proportion And Characteristics Of Transient Nodules In A Retrospective Analysis Of Pulmonary Nodules

( Jin Yeong Yu ),( Su Young Chi ),( Hee Jung Ban ),( Yong Soo Kwon ),( In Jae Oh ),( Kyu Sik Kim ),( Yu Il Kim1 ),( Sung Chul Lim ),( Song Choi ),( Yun Hyeon Kim ),( Young Chul Kim ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.-

Ⅲ-Ⅴ족 반도체의 연구 : GaAs의 합성, 단결성 및 특성 Crystal Growth and Characterization of GaAs

이형재,김영기,신영진,박해용,정양준,최춘태,김병호,김진성 全北大學校 基礎科學硏究所 1982 基礎科學 Vol.5 No.1

Temperature of 618 and 1250℃ at As and Ga sities respectively in the horizontal Bridgman furnace and growht speed of 0.7cm/h were found to be optimal for the production of single crystalline GaAs. Self-seeded and unintentionally doped GaAs crystals showd n-type characteristics with Hall mobillity of ∼0.75㎡/V-sec and carrier density of ∼10^19 m^-3 when the mesurements were made right after the growth. About three month later it was found that the same samples were converted to p-type GaAs. The analysis on the p-type sample showed that impurity scattering is dominant at around room temperature and thus the measured Hall mobility was 0.0065㎡/V-sec at 300K. 7.4±0.6 eV was obtained for acoustic deformation potential in the heavy hole band by fitting the theoretical conductivity and Hall coefficient to the corresponding experimental data. The value is very much higher than the theoretically estimated value, 3.6eV. The carrier density variation with temperature obtained from the present analysis gave 0.38 and 0.17 eV respectively for the activation energies of donor and acceptor.

8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염

홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

지문 융선의 방향성 특징추출을 위한 영상 처리

김은영,양영수,강진석,김장형,최연성 제주대학교 공과대학 첨단기술연구소 2002 尖端技術硏究所論文集 Vol.13 No.2

In this paper, it was presented that broadly delivered scanner devices can also used in fingerprint recognition process and then modified existing steps of fingerprint image processing. First, using the adaptive binary method, that effect was certified already, increased the effect of the results. And then, applying table mapping methods that looks for elements from look-up table, decreased the processing time, too. Finally, it was presented that ridge-direction characteristics extracted from these processes can used effectively in the area of fingerprint recognition system.

中國文學批評史上「神」·「道」에 대한 考察

金進暎 부산외국어대학 1985 논문집 Vol.3 No.-

In studying chinese literature, the method that only interpret the literary works and give them some meaning without any precedent survey on their historically continued literary ideas may lead to a prejudiced conclusion which is beyond from their orthodoxical ideas about literary realities. Kuo Shao Wu(郭紹虞) indicated that among the most important ideas in the history of chinese criticisms are Shen(神) and Tao (道). James Liu explained hat the metaphysical theories by Chinese criticisms focus on the idea of Tao (道). As metaphysical ideas, Shen and Tao in the literary criticisms must be considered from their own origin of confucism and taoism. And They need to be analysed interrelationally, not individually and investigated on the base of historical point of view. But these terms of chinese literary criticism seem to have little relation with the realities of popular literature. This fact induces that the history of literary criticisms differs form that of literary works and it can not include the whole literary realities.

飼料作物 Alfalfa(Medicago sativa L.)品種別 生育狀에 대하여

김무성,노영덕,김세영,백남인,정우진 경희대학교 부설 식량자원개발연구소 1996 硏究論文集 Vol.17 No.-

서로 특성이 다양한 32개의 도입한 Alfalfa품종을 우리나라 중부지역인 충청남도에 재배하여 초장과 건물중 등의 생육상태를 비교, 검토한 결과는 다음과 같다. 1. 평균초장이 큰 상위 10개 품종들은 Dekalb brand 135 > Diamond > Pioneer brand 581 > Raidor > Pioneer brand532 > Pierce> Nitro > Sparta ) Florida 77 > Sapphire의 품종순 이 며, 초장이 작은 10개 품종을 최하위 순으로 열거하여 보면 Salute < Spredor 2 < LS-1920 < Arrow < Challenger < Milkmaker < Armor < Pioneer brand 545 < Pioneer brand 5262 < Saranac의 품종 순이였다. 2. 총건물 수량이 많은 상위 10개 품종들은 Diamond > Nitro > Dekalb brand 120 > Dekalb brand 135 > Drummer > Saranac > Sapphire > Raider > Magnum > Dekalb brand 167의 품종 순이며, 건물수량이 적은 최하위 순으로 10개 품종은 Milkmaker < Pioneer brand 526 < Pioneer brand 5262 < Salute < Pioneer brand 555 < Decathlon < Pioneer brand 5929 < LS-1920 < Pioneer brand 581 < Husky의 품종들이였다. 3 평균초장과 총건물 수량의 결과를 비교하여 보면 대체로 초장이 우세하였거나, 열세하였던 품 종들이 다소간 건물수량이 우세하거나 열세하였으며, 정비례한 결과는 보이지 아니하였다. 4. 생육상태 및 건물수량이 모두 좋은 품종들은 Diamond, Nitro, Dekalb brand 135, Sapphire, Raidor품종들이며, 우리나라 중서부지역의 재배환경에 적합한 품종으로 사료된다 This study was conducted to select the best adapted alfalfa cultivars among the 32 introduced alfalfa cultivars with different characteristics in Chung-Chong Nam Do, Korea, environmental condition. Mean of plant height and total dry matter yields per cultivar from May to August in 1996 were determined. On the point of mean of plant height, ten high ranked cultivars among the 32 alfalfa cultivars in high order were Dekalb brand 135>Diamond>Pioneer brand 581>Raidor>Pioneer brand 532>Pierce>Nitro>Sparta>Florida 77>Sapphire and ten low ranked cultivars in low order were Salute<Spredor 2<LS-1920<Arrow<Challenger<Milkmaker<Armor<Pioneer brand 545<Pioneer brand 5262<Saranac. Ten high ranked cultivars from 32 alfalfa cultivars on the total dry matter yields in high order were Diamond>Nitro>Dekalb brand 120>Dekalb brand 135>Drummor>Saranac>Sapphire>Raidor>Magnum>Dekalb brand 167 and ten low ranked cultivars in low order were Milkmaker<Pioneer brand 526<Pioneer brand 5262<Salute<Pioneer brand 555<Decathlon<Pioneer brand 5929<LS-1920<Pioneer brand 581<Husky. Total dry matter yields of per cultivar was also slightly greater but It was not appeared direct proportion when alfalfa cultivar was appeared higher mean of plant height compared with those which were lower mean of plant height. Leading alfalfa cultivars for plant growth and dry matter yields were Diamond, Nitro, Dekalb brand 135, Sapphire, Raidor cultivar which can be well grown under moderate temperatures zone of midwest in Korea.