유아의 구강관리에 관한 보호자의 인지도 조사

김명진,선예경,심연수 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2

전반적인 유아의 구강관리에 관한 보호자의 인지도를 알아 보고, 이를 통한 구강관리에 대한 동기유발을 목적으로 1998년 7월부터 1998년 8월까지 삼성서울병원 소아과에 내원한 아동과 강남구 일원동 일대 유치원 및 어린이집 8곳의 만 3세 이하 아동 350명의 보호자를 대상으로 시행한 설문 조사를 통해 다음과 같은 결과를 얻었다. 1.남성보다는 여성이, 그리고 교육정도가 높을수록 치과 지식정도가 높았으며, 연령이나 경제 수준과는 무관하게 나타났다. 2.치아의 생성시기에 대해 응답자의 59%가 태아기라고 답하였다. 3.구강관리 시작시기는 응답자의 76%가 맹출 전이라고 하였으며, 63%가 실제로 만 1세 미만에 구강관리를 시작한다고 하였다. 4.구강관리 방법에 대해 응답자의 70%가 거즈를 사용한다고 하였다. 5.응답자의 57%가 만 1세 이후에도 계속 수유한다고 하였다. 6.우유병 우식증에 대한 인지도는 45%로 나타났다. 7.유치수복의 필요성에 대하여서는 90%가 필요하다고 하였으며, 31%에서 최초의 치과 내원시기를 만 2세 경이라고 하였다. 8.47%의 보호자가 치아우식이 감염성 질환임을 인식하지 못하였다. 9.응답자의 33%만이 임신 중 치과 검진을 받았다고 하였고, 소아과나 산부인과에서 구강관리에 관한 지도를 받은 것은 11% 뿐이었다. 10.주로 육아 서적에서 유아의 구강관리에 관한 정보를 얻는 것으로 나타났다. 11.보호자들의 전반적인 치과지식과 실천정도는 유아들에게 적절한 구강관리를 제공하기에 충분치 않은 것으로 나타났다. 주요어 : 유아, 구강건강관리, 부모, 교육

대형경유차 저공해기술 적용에 따른 나노입자 배출특성

임철수,류정호,엄명도,황진우,김예은 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.2

Diesel engines which emit a lot of PM and NOx have been known as a main air polluter. Especially, diesel particulate matters (DPM) including black smoke are hazardous air pollutants to human health and environment. The nations retaining advanced engine technologies have reinforced emission regulations. To meet these regulations diesel engine manufacturers have developed low-emission diesel engines, aftertreatment equipments, alternative fuel technologies and so on. In this study, particle number concentrations characteristics according to particle size and engine driving conditions were analyzed when these low-emission technologies were applied. There was a tendency of increasing particle number concentrations from heavy-duty diesel engines with increasing engine rpm and load rate. In the cases of CDPF (Catalytic Diesel Particulate Filter), CNG (Compressed Natural Gas) engine and ULSD (Ultra Low Sulfur Diesel) more than 99% of particle number concentration were removed.

사무직 근로자의 수면의 질 및 직무스트레스와 우울과의 관련성

강미나,강수영,권수정,김현주,배재원,이보연,이예진,임의롬,정다영,조한솔 이화여자대학교 간호과학대학 2013 이화간호학회지 Vol.- No.47

Purpose: The purpose of this study was to understand the degree of depression, sleep quality, job stress and their association among office workers. Method: A self-administered questionnaire was distributed to 147 workers employed in 5 big enterprises, and 5 small and medium enterprises from October 21 to November 21, 2012. The questionnaires included socio-demographic and health-related characteristics, job-related characteristics, sleep quality, job stress (KOSS) and depression (CES-D). Result: Among all subjects, 23.1% was in the depression group (21 points and over in the CES-D score). Depressive level was positively correlated with job stress and quality of sleep. The adjusted odd ratio for the effects of sleep quality and job stress on depression significantly increased in the depression group compared to that of the normal group. Multiple regression analysis revealed that the following factors of influence had combined explanatory powers on depression: BMI, life satisfaction, quality of sleep, and job stress. Conclusion: The study revealed that complicated influences were exerted on the level of depression by variable factors, as well as socio-demographic characteristics, health-related characteristics, quality of sleep, and job stress. Specifically, the level of depression was influenced by the quality of sleep and job stress.

혈액암환자에서 조혈모세포 이식 후 따르는 헤르페스 바이러스 감영 양상

이호섭,탁희상,신성훈,김양수,남성진,김혜수,박진희,정수현,김성빈,김예나 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.1

배경 : 헤르페스바이러스과에는 단순포진 바이러스(HERPES SIMPLEX VIRUS, HSV), 수두대상포진 바이러스 (VARICELLA-ZOSTER VIRUS, VZV), 엡스타인-바 바이러스 (EPSTEIN-BARR VIRUS, EBV), 그리고 거대세포 바이러스 (CYTOMEGALOVIRUS, CMV) 등이 있다. 헤르페스바이러스 감염은 혈액암환자에서 조혈모세포 이식 환자에서 전파 (dissemination), 이차감염, 세균 중복 감염의 심각한 합병증을 일으킬 수 있다. 하지만 항암약물치료를 받는 림파종 환자에서 항 바이러스 약제의 사용 용량과 기간에 대한 concensus는 없다. 헤르페스바이러스 감염에 대한 발생율과 위험인자를 후향성으로 분석하였다. 방법 : 고신대학교 복음 병원에서 1995년 6월부터 2009 년 2월 사이에 새롭게 진단되어 조혈모세포 이식을 받은 전체 58명의 환자들이 후향적으로 현 연구에 등록했다. 헤르페스 바이러스 감염은 임상적 진단, 혈청학적 검사 또는 병리학적 진단에 기초하여 확진한다. 환자들의 특성은 다음과 같다: 평균 연령은 44세 (범위 19-62세)였고 남녀비는 30:28이었다. 등록된 질환은 백혈병 (n=9, 15.5%), 림프종 (n=30, 51.7%), 다발성 골수종 (n=12, 20.7%), 재생불량성 빈혈 (n=6, 10.3%) 그리고 골수이형성증후군 (n=1, 1.7%)이 포함되었다. 결과는 chi-squre test나 independent samples T test를 사용하여 분석되었다. Multivariate analysises에 대해 logistic regression test를 사용하였다. 결과 : 15명의 환자들 (25.9%)에서 조혈모세포 이식후 헤르페스 바이러스 감염이 발생하였다. 조혈모세포 이식 5년간 누적 발생율은 53.9%였다. Univariate analyses에서 헤르페스 바이러스 감염에 대한 유의한 위험 인자는 없었다. 하지만 조혈모세포 이식후 생존 기간(40.18 ± 30.14 months vs 20.06 ± 26.67 months, p=0.018)은 헤르페스 바이러스 감염의 낮은 발병율과 유의한 관련성이 있었다. 이식 편대 숙주질환 (GVHD)의 존재 (37.5% in developed GVHD vs 0% in no GVHD, p=0.200), 동종조혈 모세포 이식에서 면역억제요법의 기간 (15.98 ± 14.02 months vs 6.78 ± 3.67 months, p = 0.374)은 헤르페스 바이러스 감염에 대한 위험인자가 아니었다. 결론 : 조혈모세포 이식 후 생존 기간은 어사이클로비어 예방을 받은 혈액암 환자에서 헤르페스 바이러스 감염의 낮은 발병율과 연관성이 있는 것으로 보인다. 저용량의 어사이클로비어 예방은 헤르페스 바이러스 감염의 고위험군인 조혈모세포 이식을 받은 혈액암 환자에 필요하리라 생각된다. Background : Herpesviridae family includes herpes simplex virus, varicella zoster virus, Epstein-Barr virus, and cytomegalovirus, etc. Herpesviridae viral infection (HVI) can lead to serious complications including dissemination, secondary infection, bacterial superinfection in patients with hematologic malignancy following hematopoietic stem cell transplantation (HSCT). But there was no consensus on the dose and duration of antiviral agents prophylaxis in patients undergoing chemotherapy. We retrospectively analyzed the incidence and the risk factors for HVI. Method : A total of 58 patients who newly diagnosed and received HSCT with prophylaxis of acyclovir at the Kosin University Gospel Hospital, Busan, Korea between June 1995 and February 2009 were enrolled retrospectively in the current study. HVI was confirmed based on clinical diagnosis, serologic test or pathologic diagnosis. The characteristics of the patients were as follows: the median age was 44 years (range 19-62 years) with a female-to-male ratio of 30:28. The enrolled diseases included leukemia (n=9, 15.5%), lymphoma (n=30, 51.7%), multiple myeloma (n=12, 20.7%), aplastic anemia (n=6, 10.3%) and myelodysplastic syndrome (n=1, 1.7%). The results were analyzed using a chi-square test and independent samples T test. For the multivariate analysis, we used logistic regression test. Results : Fifteen patients (25.9%) developed HVI after HSCT. The cumulative incidence of HVI was 53.8% at 5 years after HSCT. In univariate analysis, there was no significant risk factor for HVI. The presence of graft-versus-host disease (GVHD) (37.5% in developed GVHD vs. 0% in no GVHD, p=0.200), duration of immunosuppressive therapy (IST) in allo-SCT (15.98 ± 14.02 months vs. 6.78 ± 3.67 months, p = 0.374) were not risk factors for HVI. Conclusion : The incidence of HVI was similar to that in historical other studies. There was no risk factor associated with development of HVI. Most of the HVI occurred within the first 24 months after transplantation. So long term use of antiviral prophylaxis may be needed to prevention of HVI after HSCT.

Visual Disturbance Caused by a Nail Gun-Induced Penetrating Brain Injury

( Jin Bong Ye ),( Young Hoon Sul ),( Se Heon Kim ),( Jin Young Lee ),( Jin Suk Lee ),( Hong Rye Kim ),( Soo Young Yoon ),( Jung Hee Choi ) 대한외상학회 2021 大韓外傷學會誌 Vol.34 No.3

Penetrating brain injury caused by a nail gun is an uncommon clinical scenario reported in the literature. A 36-year-old male presented with a nail that had penetrated through the occipital bone. He was alert and neurologically intact except for visual disturbance. Computed tomography (CT) of the brain showed the nail lodged at the occipital lobe and the parietal lobe, with minimal intracerebral hemorrhage. The nail was placed in the occipital lobe close to the superior sagittal sinus. We removed the nail with craniotomy since the entrance of the nail was close to the superior sagittal sinus. There were no newly developed neurological deficits postoperatively. Immediate postoperative CT showed no newly developed lesions. The patient recovered well without any significant complications. Two weeks postoperatively, magnetic resonance imaging showed no remarkable lesions. The visual disturbance was followed up at the outpatient department. To summarize, we report a rare case of penetrating head injury by a nail gun and discuss relevant aspects of the clinical management.

Intronic long nonciding RNA and sumoylation of histone methyltransferase contribute to control of flowering time in rice

Ye Jin Kwon,Do Youn Kim,Sung-il kim,Jun Soo Kwak,Jong Tae Song,Hak Soo Seo 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

Flowering time is a important agronomic trait for grain production in rice. So the control of flowering time is a critical step. In Arabidopsis, expression of certain key flowering gene such as FLOWERING LOCUS C (FLC) is known to be epigenetically regulated by chromatin modification through Enhancer of Zeste[E(z)], a histone methyltransferase, that core component of repressive complex, polycomb repressive complex2(PRC2). However, the chromatin mechanism involved in the regulation of rice flowering genes is presently not well known. Here we show that predict coding region of a intronic LncRNA[termed rice COLDAIR(OsCOLDAIR)], which is expected to associate with a component of PRC2, is predicted at rice FLC gene. And additionally we suggest interaction of histone methyltransferase and E3 SUMO ligase that indicate possibility of interaction with rice E(z) gene and rice E3 SUMO ligase. Our study contribute to control of rice flowering time by observing two factor that can regulate expression of related of rice FLC gene.

Determination of biotin in foods for special dietary uses using HPLC with immunoaffinity column cleanup extraction

Soo Jin Bang,Bo Young Oh,Min Ji Ye,Soo Jung Hu,Hye Young Lee 한국분석과학회 2019 학술대회논문집 Vol.2019 No.11

A Herpes Simplex Virus Infection Secondary to Acupuncture and Cupping

Ye-Jin Jung,Jae-Hong Kim,Hae-jin Lee,Hana Bak,홍승필,Soo Young Jeon,안성구 대한피부과학회 2011 Annals of Dermatology Vol.23 No.1

Acupuncture and cupping have a public reputation as being safe even though these practices can lead to complications such as trauma or infection. We report here on a case of herpes simplex virus (HSV) infection secondary to acupuncture and cupping in a 56-year-old woman. The patient, who had a history of acupuncture and cupping on her left forearm for treating her myalgia, developed painful papules. Histologically, the biopsy specimen showed characteristic ballooning degeneration and inclusion bodies in the epidermis and mid-dermis. These clinical and histological findings were consistent with the diagnosis of HSV infection. (Ann Dermatol 23(1) 67∼69, 2011)

Spontaneous vaginal hemorrhage caused by choriocarcinoma : Necessity for the early diagnosis and treatment

( Ye Jin Seon ),( Ji Hye Kim ),( Yun Dan Kang ),( Jin Wan Park ),( Jong Soo Kim ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-

Hemorrhagic choriocarcinoma lesions may lead to life-threatening conditions, but an early diagnosis contributes to a potential cure. We report a case of an woman with choriocarcinoma, that occurred within one month after full term delivery. The 25-year-old patient with gravida 1, para 1 was admitted in our hospital for massive vaginal bleeding and dry cough. Radiological investigation found a 8.4cm mass in enlarged uterus and also multiple nodules in both lungs. Her serum β-hCG level was 747,682 mIU/mL. An emergency surgery was performed to control heavy vaginal bleeding. The patient was early diagnosed as choriocarcinoma FIGO stage III and the score of the Prognostic Scoring Index modified by the WHO was 12. Multiagent chemotherapy, the EMACO regimen(etoposide, actinomycin D, methotrexate, vincristine and cyclophosphamide) was administered. After the seventh chemotherapy session, her serum β-hCG level was <5 mIU/mL. The diagnosis of choriocarcinoma may be difficult, especially in the setting with the limit of medical resources. The early application of various diagnostic techniques such as x-ray, computed tomography is helpful for evaluating the patient´s condition.

The Huge ovarian mass mimicking a uterine sarcoma

( Ye Jin Seon ),( So Ryeoung Kim ),( Ji Suk Han ),( Hee Young Ahn ),( Eun Jin Heo ),( Yun Dan Kang ),( Jong Soo Kim ),( Jin Wan Park ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Uterine sarcomas are rare mesodermal tumors that account for 3-7% of uterine cancer. They are a heterogeneous group of tumors and have poor prognosis. It is difficult to diagnosis at preoperatively, that the positive predictive value using image study such as Abdominal Pelvis computed tomography (AP-CT) or Pelvis magnetic resonance (MRI) scan is very low. We present a rare case of the primary ovarian fibrothercoma mimicking uterine sarcoma. A 89-years old postmenopausal women present with progressive abdominal pain and palpable abdominal mass. AP-CT revealed about 16cm sized uterine was suspected uterine sarcoma. Tumor markers are normal range. She underwent exploratory laparotomy. There are a huge irregular hard mass with several feeding vessels originated right ovary and grossly normal uterus and left adnexa. A surgical exploration was performed within whole abdomen. there was no metastatic nodules. we performed Right salpingo-oophorectomy and requested frozen biopsy at pathologist. It was a ovarian stromal tumor. Therefore, we performed total hysterectomy, Left salpingo-oophorectomy and both pelvic lymph node biopsy. The final pathologic diagnosis documented an ovarian fibrothecoma. This case reported an unusual case of the primary ovarian fibrothecoma mimicking uterine sarcoma.