중세어 ‘지-’ 구성의 현대어 수용 양상에 대해

양지현(Yang, Ji-hyeon),황병순(Byung-sun Hwang) 언어과학회 2016 언어과학연구 Vol.0 No.79

‘JI-’ having a meaning of desire, was used in the composition of ‘V JI-’, ‘V EOJI-’, ‘V GOJI-’ in the medieval language, ‘-JYEO’ in ‘V JYEO’, which is a component of ‘V JI-’, was transformed to ‘-JA’ in the contemporary language. ‘V JYEO HA’, an extensive form of ‘V JI-’, was abbreviated with ‘HA’ and integrated with ending behind ‘HA’, which formed ‘-JAMYEON’, ‘-JANI’ and ‘-JAGO’ in the contemporary languages. ‘V EOJI-’ disappeared. ‘v GOJI-’ is generally used as an extension. Among extension forms, ‘V GOJEO HAYA’ in ‘V GOJEO HA’ composition was abbreviated with ‘HA’ and transformed to ‘-GOJA’ in the contemporary language. ‘V GOJYEO SIB-’ composition was abbreviated to ‘-GO SIP-’ in the contemporary language and is also used as ‘-GOP’ with the more abbreviated form. This component is used as dialect in some areas in the form of ‘-GOJEOB/GOJEOP-’.

Multiplex PCR Detection for 3 Events of Genetically Modified Maize, DAS-59122-7, TC6275, and MIR604

Ji-Hye Ahn,Jae-Hwan Kim,Su-Youn Kim,Woo-Young Lee,Sun-Hee Park,Hae-Yeong Kim 한국식품과학회 2008 Food Science and Biotechnology Vol.17 No.3

A multiplex polymerase chain reaction (PCR) method was developed to simultaneously detect 3 events of genetically modified (GM) maize. The event-specific primers were used to discriminate the following 3 events of GM maize (DAS-59122-7, TC6275, and MIR604) using multiplex PCR method. The zein gene was used as an endogenous maize reference gene in the multiplex PCR detection. The primer pair Zein-F/R producing a 99 bp amplicon was used to amplify the zein gene. The primer JI-Das-F1/R1 for DAS-59122-7, JI-TC6275-F3/R3 for TC6275, and JI-MIR F1/R1 for MIR604 yielded an amplicon of 130, 162, and 197 bp, respectively. The detection limit of multiplex PCR was 1% for DAS-59122-7, TC6275, and MIR604 for one reaction.

[P8-249] Capsanthin, the Main Compounds in Red Paprika Fruit (Capsicum annuum L.), Prevents H<SUB>2</SUB>O<SUB>2</SUB>-Induced Inhibition of Gap-Junction Intercellular Communication

Ji?Sun Kim,Jiyun Ahn,Sun-hye Lim,Suna Kim,Tae-Youl Ha 한국식품영양과학회 2010 한국식품영양과학회 학술대회발표집 Vol.2010 No.10

Claudin-1 expression decreases with increasing pathologic grade in actinic keratosis and may be used as a marker of high-risk actinic keratosis

( Ji Su Lee ),( Hyun-sun Park ),( Hyun-sun Yoon ),( Soyun Cho ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Actinic keratosis (AK) is a common sun-induced skin disorder of importance for the progression to invasive squamous cell carcinoma. However, there is still no good way to predict high risk AK. Objectives: To identify markers which reflect the biologic behavior of AK and to understand the pathogenesis of AK Methods: A total of 52 patients with AK and site-matched 17 normal controls were included. We evaluated solar elastosis and immunohistochemical features using the following antibodies: p53, vitamin D receptor (VDR), claudin-1, and Langerin. Results: Solar elastosis increased and Langerhans cell (LC) density decreased with aging in both patients and controls. Solar elastosis and p53 expression were higher and VDR expression was lower in patients than controls; however, they showed no statistical difference in relation to the pathologic grade of AK. Claudin-1 expression gradually decreased from normal control to severe AK and decreased in the areas with epidermal atypia. LC density in severe AK was significantly lower than in normal control and mild AK; no difference in LC density was seen among control, mild AK and moderate AK. Conclusion: Claudin-1 can be a useful marker of pathologic severity of AK. In contrast, p53 increases and VDR decreases in AK not in gradual manner but in the early steps of carcinogenesis. LC density is relatively maintained in AK until it reaches severe dysplasia.

Atypical pigmented basal cell carcinoma mimicking traumatic pigmented tattoo

( Ji Won Kim ),( Hyun-sun Park ),( Hyun-sun Yoon ),( Soyun Cho ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Basal Cell Carcinoma, the most common type of skin cancer in humans, usually develops in the sun-exposed area of head and neck. A 63-year-old woman presented with 1-year history of a bean-sized, slightly protruded bluish dermal patch in her right para-nasal area, and it gradually increased in size after she perceived its presence. It looked like traumatic pigmented tattoo because of bluish color and flat patchy features. A punch biopsy was performed, and the lesion was diagnosed as a basal cell carcinoma (BCC). Histopathologically, melanophages were seen scattered between typical basaloid BCC tumor nests in the reticular dermis, making the lesion appear similar to a traumatic pigmented tattoo by Tyndall effect. Typically pigmented BCC appears as a hyperpigmented, translucenet papule which may also have eroded borders. The patient only showed bluish colored patch without eroded borders, making it appear clinically similar to a pigmented tattoo. Herein, we report an interesting case of pigmented BCC which mimicked traumatic pigmented tattoo but was confirmed to be a BCC by biopsy.

Hairless Mice를 이용한 광노화 모델에서 APB-01의 경구반복투여에 의한 피부주름개선 효과 시험

이지해(Ji-Hae Lee),이병석(Byung-Suk Lee),변범선(Bum-Sun Byun),김완기(Wan-Gi Kim),이상준(Sang-Jun Lee),심영철(Young-Chul Sim),김배환(Bae-Hwan Kim) 한국독성학회 2003 Toxicological Research Vol.19 No.4

Ultraviolet (UV) is thought to induce erythema, sun-burn, photo-toxicity, photo-allergy, photo-aging and sometimes skin tumor. To investigate the photo-protective effects of APB-01 (Amore-<br/> Pacific Beauty-01, the mixture of Jaummi-dan and Fujiflavone P10) on UV-induced skin damage, forty of SKH hairless female mice were orally administered with APB-01 or saline fifth a week, and irradiated with UV third a week for up to ten weeks. We examined the relationship between visible changes and skin damage in the dermis and epidermis. In the APB-01 treated group, a better skin<br/> and less wrinkles formation were observed when compared to the UV control group. This results demonstrated that oral administration of APB-01 seems to have photo-protective effects on UV-induced<br/> skin damage of hairless mice due to an inhibitory effect on collagen breakdown, and the model using hairless mice is very useful to investigate the efficacy of functional beauty foods.

『표해록(漂海錄)』과 『승차록(乘蹉錄)』에 나타난 산동(山東) 인식의 비교

손지수 ( Ji Si Sun ) 경상대학교 남명학연구소 2014 남명학연구 Vol.44 No.-

본고에서는 崔溥의 .漂海錄.과 崔斗燦의 .乘.錄.에 나타나는 두 저자의 산동 인식을 각각의 시대 별로 살펴보았다. 중국 당나라와 원나라는 국제화 정책을 시행하여 많은 유학생을 수 용했다, 그러나 명나라 건국 이후에는 쇄국정책을 실시하여 유학생 수 용을 금지했다. 이로 인해 조선의 선비들은 중국을 경험할 수 있는 기회 가 줄었고, 대체로 책을 통해서 중국을 체험하게 되었다. 명.청 시기, 조선에서 공식적으로 파견한 사신들은 중국에 관한 기록을 남겼으나, 사신의 신분으로는 북경 이남 지역의 경험이 불가능했기 때문에 북경 이외의 지역에 대한 기록은 찾아보기 어렵다. 한편, 비공식적인 漂流人 의 경우 북경 이남 지역을 경험하고 기록을 남기기도 했는데, 그 가운데 崔溥와 崔斗燦의 저작이 가장 대표적이다. 崔溥와 崔斗燦은 표류인의 자격으로 북경 이외의 지역을 경험했으며 이러한 경험이 담겨 있는 .漂海錄.과 .乘.錄.은 연구 자료로서 중요성을 띤다. 성종 연간에 관인 崔溥 일행은 제주도 앞바다에서 태풍을 만나 표류 하게 되었다. 그리고 순조 연간, 장인인 제주 대정현감 金仁澤의 요청으로 제주도로 떠난 崔斗燦은 1년 후 귀향길에서 큰 풍랑을 만나 표류하 게 되었다. 성종 17년(1486) 중국에 표류한 崔溥를 이어, 崔斗燦은 300여년 후인 순조 18년(1818) 중국에 표류했다. 두 시기 모두 조선 왕조는 이어지고 있었지만, 중국은 왕조가 바뀐 완전히 다른 시대였다. 같은 지역이라 하더라도 다른 시대 배경 아래서 겪는 체험과 감상은 다를 수밖에 없었다. 두 시대의 국가 경제와 국민 생활의 차이 등 다양 한 면에서 동이점을 찾아볼 수 있다. 한편으로 崔溥는 조선 시대의 관인 으로서 어명을 받아 .漂海錄.을 작성한 것에 반해, 崔斗燦은 자신의 취미대로 .乘.錄.을 기록했다. 이러한 점 역시 두 텍스트의 차이를 야기했다. 崔溥는 매우 상세하고도 다양한 범위의 내용을 기록했으나, 집필의 의무가 없었던 崔斗燦의 텍스트에는 감정의 표출의 기록과 詩 歌가 빈번하게 나타난다. This study analyzed two authors`` experience in Shandong, represented by their works『漂海錄』 by 崔溥 and『乘蹉錄』by 崔斗燦, according to the era they lived in. The Tang and Yuan dynasties of China had open international policies and accepted many students studying abroad from foreign regions. The establishment of Ming dynasty and adoption of isolationist policy, however, led to abolishment of foreign students. Thus, scholars of Chosun had few opportunities to have experience in China, and resorted to learning about the country through books. In Ming/Qin dynasties, official ambassadors sent from Chosun left records of China, but their access as ambassadors prohibited travel south of Beijing. Therefore, records describing regions outside Beijing are sparse. Yet, unofficial 漂流人 were able to access regions south of Beijing and make records, the most representative of which are works by 崔溥 and 崔斗燦. These authors were able to experience regions outside Beijing as drifters, and 『漂海錄』and 『乘 蹉錄』, which depict their experiences, have significance as important primary sources for research. 崔溥, an official from Seong-Jong``s rule, encountered a typhoon in the seas near Jeju and became a drifter. 崔斗燦, who left for Jeju bythe request of his father in law 金仁澤 - a governor of DaeJung in Jeju, also encountered a big typhoon on his return journey and became a drifter. 崔溥 grounded on Chinese shore in 1486, 17th yearofSeong-Jong``srule,and崔斗燦 grounded 300 years later on 1818, 18th year of Sun-Jo``s rule. While Chosun dynasty had endured through both periods, China had experienced a transition into a completely different dynasty. Thus the experience of living in a different era and rule, even though the physical geography remained the same, had to be changed significantly. With the works, many similarities and differences can be found between the two eras in a range of topics such as national economy and civilian living standards. While崔溥, as an official from Chosun, received royal command to record his experience in 『漂海錄』, 崔斗燦 recorded 『乘 蹉錄』at his own leisure. This contextual difference of the two records contributed to differences in their content: 『漂海錄』covers a wide range of topics in meticulous detail, but 『乘蹉錄』, in which the author had no obligations, often contains records of emotional expressions and 詩歌.

A rare case of abdominal adenoid basal cell carcinoma in a patient with a history of radiation therapy

Kim, Ji Hun,Kim, Sun Eung,Cheon, Young Woo Korean Society of Plastic and Reconstructive Surge 2020 Archives of Plastic Surgery Vol.47 No.1

Basal cell carcinoma (BCC) is the most common skin cancer and its incidence is steadily increasing. Prior radiation therapy is one of the most important risk factors for BCC. Although the mechanism remains undefined, long-term studies have shown that people exposed to radiation have an increased risk of BCC. Despite the fact that BCC occurs most frequently in sun-exposed areas of the body, patients with a history of radiation therapy have an increased risk of BCC in areas previously exposed to radiation. Here, we report a case of adenoid BCC on the abdomen in a 67-year-old woman after radiation therapy post-hysterectomy.

복합문화공간의 색채계획 : 수원시 영통구 상업지구를 중심으로

서주환,여화선,최선주,박선영,김옥경,승지현,김홍균 경희대학교 부설 디자인연구원 2007 예술· 디자인학연구 Vol.10 No.1

The recognition on leisure living which have been enjoyed by prestige level from popular persons is now widely spreaded in modern capitalism society and change of the leisure living influenced very much to the society and Industry. The 5 day work per week system expanded to the school and contemporary leisure living of the people is recognised as one culture with various contents. This change of leisure living made a recognition on the need for a space for leisure culture contents, which related to a creation of Complex-culture facility to contain various type of multiple leisure culture. The Complex-culture facility is mainly focused on the entertainment space with increased leisure living, which is consist of important element of the Complex-culture facility as performance space, exhibition, sports and shopping space to construct performance hall, theater, exhibition room, sports center, shopping mall, leisure space and plaza. This study, therefore, will Investigate on the function and value of color, and review on the cases of Complex-cultural facility and then choose a space of cultural element lack. It will recompose in Complex-cultural facility.

Differentiation of Desmoplastic Spitz Nevus from Similar Conditions

( Min-woo Kim ),( Ji Soo Lim ),( Yun Seon Choe ),( Jung Ho Kim ),( Hyun-sun Yoon ),( Soyun Cho ),( Hyun-sun Park ) 대한피부과학회 2016 대한피부과학회지 Vol.54 No.9

The diagnosis of classic Spitz nevus with characteristic histopathologic findings is often straightforward, but unusual variants can cause diagnostic difficulties. Desmoplastic Spitz nevus (DSN) is of particular importance, as its differential diagnosis from other diseases, including desmoplastic malignant melanoma (DMM), is essential but often difficult¹. A 38-year-old Caucasian woman presented with a 6-mm brownish papule of unknown onset on the dorsum of her left hand (Fig. 1A). She did not report any change in the papule size, trauma history, or related symptoms, but she wanted to have the lesion removed. Punch excision of the specimen revealed proliferation of individual spindle and epithelioid cells with scanty pigmentation within dense colla-genous dermal stroma (Fig. 1B, C). The specimen was focal positive for S-100 and HMB-45, positive for Melan-A, and 1% positive for Ki-67 (Fig. 2A∼C). The lesion did not recur after punch excision at the 1-year follow-up. Since its first report in 1975, there have been only a few case series of DSN owing to the rarity of this disease and its under-recognition, except for intermittent case reports^1-3. DSN usually presents as a small red-brown papule on the trunk and extremities. It can occur at any age, but is mostly observed in young adults, with a slight female predominance. The distinctive histopathologic features of DSN―an intradermal growth pattern of large spindle or epithelioid nevus cells embedded in a fibrotic stroma, sparse melanin pigment, no junctional activity, no Kamino bodies, no prominent nest formation―can aid its differentiation from clinical simulators. Additionally, immunohistochemistry is essential for a differential diagnosis. DSN tests positive for S-100, Melan-A, and HMB-45, whereas dermatofibroma is negative for all three³. Hypomelanotic blue nevus shows uniform positivity for HMB-45, whereas DSN shows differential expression in most spindled cells3. The distinction between DSN and DMM is the most important. DMM is more common in elderly patients and tends to occur on sun-damaged head and neck areas. It also shows cellular atypia, strong mitotic activity and Ki-67 expression, less frequent S-100 and Melan-A positivity, and almost exclusive negativity for HMB-45^2,3. Some researchers regarded DSN as an end stage of Spitz nevus that had lost continuity with the epidermis and undergone fibrosis. Paniago-Pereira et al.² also reported that DSNs occurred in patients older than 30 years. These findings suggest that desmoplasia might be an aging process of Spitz nevus. However, Barr et al.1 found no significant difference in patient age, disease duration, or trauma history between patients with DSN and common variants of Spitz nevus, and suggested that desmoplasia may be a tumor-induced reactive stromal induction rather than a regressive phenomenon. The pathogenesis of desmoplasia has not yet been clearly elucidated. Moreover, it is controversial whether DSN should be regarded as a variant of Spitz nevus or whether it belongs to a spectrum of desmoplastic nevus as a distinctive entity^3,4. Some researchers5 suggested strict diagnostic criteria for de-smoplastic nevus, including greater cellularity in the super-ficial portion, and a mixture of melanocytic nevus cells, ovoid and dendritic melanocytes, and spitzoid melanocytes. Further, they mentioned that lesions in which one particular type of melanocyte predominates over others are more likely to represent DSN. Dermoscopic findings can also aid the distinction, because DSN shows dotted vessels and reticular depigmentation whereas desmoplastic nevus demonstrates a delicate pigment network over a pinkish background⁴. Although it is regrettable that we did not acquire dermoscopic image to support the diagnosis, our case overall seems more com-patible with DSN. However, the probability of a morphologic spectrum that embraces DSN and desmoplastic nevus cannot be excluded, and requires further studies. Here, we report an unusual desmoplastic variant of Spitz nevus with a literature review, and propose keynotes for differential diagnosis from its simulators, especially DMM.