서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

법과학을 적용한 형사사법의 선진화 방안(Ⅱ)

강지현(Ji Hyon Kang),김민지(Min Chi Kim),김성규(KimㆍSeong Gyu),Jane Goodman-Delahunty,Paula Saunders,Mandeep Dhami,Yvette Tinsley 한국형사법무정책연구원 2011 형사정책연구원 연구총서 Vol.- No.-

허혈성 심질환에서 나타나는 황상화지수, 사이토카인 및 염증지표의 변화

전상훈,안지훈,방덕원,온영근,현민수,김성구,권영주 순천향대학교 의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

..

우리나라 어린이와 청소년의 구강건강을 위한 공공서비스의 현황과 전망

이광희,김지영,송지현,김윤희,임경욱,정승열 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.3

소아치과학이 목표로 하는 어린이와 청소년의 구강건강을 달성하기 위하여는 민간 치과의료기관에서 내원 환자를 대상으로 하는 진료만으로는 한계가 있으며 공공서비스(公共service)의 역할이 필요하다. 학교구강보건설이 설치된 초등학교는 전체의 7.2%이었고,초등학교 중에서 불소용액양치사업을 수행한 비율은 57.5%, 급식 후 집단잇솔질을 한 비율은 46.9%이었으며,초등학생 중에서 구강보건교육을 받은 비율은 48.0%, 치아홈메우기를 받은 비율은 12.4%이었다(2006년). 0∼6세 영유아의 약 42%가 지난 1년간 구강검진,불소도포,치면세마,치아홈메우기 중 하나 이상의 예방적 치과진료를 받았으며,받은 장소는 교육시설이 약 18%, 보건소가 약 1%이었다(2005년). 불소농도가 조정된 수돗물을 마시는 인구 비율은 전국 평균이 5.7%이었다(2006년). 학교구강보건사업의 발전을 위해서 행정의 일원화,보건교사에 대한 교육,구강보건교사제도의 도입,순회 학교치과의사와 학교치과병원을 통한 포괄적 진료서비스의 제공 등을 고려할 수 있을 것이다. 또한 아동·청소년 주치의제의 도입으로 민간기관을 통해 공공서비스를 강화하는 방안이 검토되고 있다. To achieve the dental health of children and adolescents which is the objective of the pediatric dentistry, the role of the public service should be increased. The basis of the public service is established by many laws of which the Dental Health Law is most important. The percentages of primary schools that had the school dental health clinic, that implemented the fluoride rinsing program, and that implemented the group toothbrushing after lunch were 7.2%, 57.5%, and 46.9%, respectively, and the percentages of primary school children that received the dental health education and that received the fissure sealing were 48.0% and 12.4%, respective1y(2006). About 42% of infants and preschool children from 0 to 6 years received preventive dental care in the last one year, at the nursery or kindergarten(18%) or at the health center(1%)(2005). The percentage of the health centers that implemented water fluohdation was 11.3%, and the percentage of the population who drank the fluoridated water was 5.7 %(2006). It was suggested that the school dental health administration should be unified, that dental health teachers should be employed, and that the comprehensive dental health care should be supplied to all the children and adolescents through the circuit school dentists and the school dental hospitals in the long term. Also, the dentist in charge system for the children and adolescent was suggested.

자가면역 용혈빈혈의 임상적 분석

박치영,강지은,박상곤,김상현,김형선,정춘해 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Background: Autoimmune hemolytic anemia (AIHA) is a very uncommon disorder with the incidence between one and three cases per a hundred thousans a year. There have been very few studies about AIHA in Korea because of its low incidence. Most AIHA studies in Korea were about case history. The aim of this study was to review the clinical features, therapy and outcome of AIHA patients in single institution clinic. Methods: We reviewed retrospectively the medical records of AIHA patients from December 2002 to December 2006. Results: Twelve patient with AIHA were identified, and their median age was 49 years (range 27-75). Male to female ratio is 9:3. The median hemoglobin level was 5.0 g/㎗ (range 2.5-8.2). Warm type AIHA was most common (8/12), cold type was three, and mixed type was one. There was histories of associated disease in six patients. Two patients were complicated by systemic lupus erythematosus and mycoplasma infection and one patient by idiopathic myelofibrosis and solid tumor. Oral steroid was used as the first-line treatment in nine patients. An initial response was observed in eight patients with complete response. One patient had not responded to the initial steroid treatment, and then showed complete response with rituximab. Two relapsed patients were treated with rituximab and partial splenic embolization. Conclusion: The majority of patients can be treated with steroid. Rituximab can improve the response rate in relapsed and refractory AIHA.

허혈성 심질환에서 나타나는 항산화지수, 사이토카인 및 염증지표의 변화

전상훔,안지훈,방덕원,온영근,현민수,김성구,권영주 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Purpose : As diet habits change and the elderly popuation increases conronary artery disease(CAD) has also increased. Recent ongoing studies on varous inflammatory indexes in acute coronary syndrome(ACS) are underway. Several study results have shown that total antioxidant status(TAS) was remarkably lower in unstable angina than in chronic stable angina and levels of interleukin-(IL-6), C-reactive protein(CRP), monocyte chemoattractant protein-1(MCP-1), P-selectin were reported to be elevated in unstable angina and acute myocardial infarction(AMI). In our study, we studied and compared the level changes of cytokines and inflammatory indexes that play important roles inside the blood vessel. Methods : Study subjects were patients who were admitted and underwent coronary angiography at the cardiology department in Soonchunhyang university hospital. Subjects were divided into 4 groups, a control group, a stable angina and unstable angina group and an acute myocardial infarction group. The clinical findings, TAS, inflammatory cytokines(P-selectin, MCP-1, IL-6), anti-inflammatory cytokines(IL-10), Homocysteine and CRP levels in each group were measured and compared. Results : The total number of study participants was 86 patients, with 26 patients in the control group, 21 patients with stable angina, 15 patients with unstable angina, and 24 patients with AMI. There were significant differences in the TAS among the 4 grouops. 1.7±0.51 mmol/L, 1.6±0.60 mmol/L, 1.4±0.20 mmol/L, 1.4±0.29 mmol/L respectively. IL-6 levels also showed a significant difference between groups, averaging 0.8±2.47 pg/ml, 2.7±3.77 pg/ml, 6.8±10.63 pg/ml, 10.9±17.43 pg/ml respectively. Homocysteine levels averaged 8.0±2.47 pg/ml, 6.8±10.63 pg/ml, 10.9±17.43 pg/ml restectively. Homocysteine levels averaged 8.0±1.0 μmol/L in the control group, 14.3±5.14 μmol/L in patients with stable angina, 16.0±4.66 μmol/L in patients with unstable angina, and 17.3±10.08 μmol/L in AMI patients. Conclusion : Compared to the control group, the TAS levels were significantly lower in patients with unstable angina and AMI. there was no difference between the control group and those with stable angina. IL-6 and homocysteine levels were also higher in patients with unstable angina and AMI. Therefore we concluded that measurements of TAS, IL-6 and homocysteine are useful in measuring the inflammatory index of coronary artery diseases and may be important factors in predicting the states and prognosis of cardiovascular disorders.

재발된 원발성 고환림프종이 동반된 류마티스 관절염 환자에서 Rituximab으로 치료한 1예

박열,박상민,한경택,강지인,이준,김상현 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Several studies have shown that patients with rheumatoid arthritis(RA) have a doubled to tripled increased risk for developing lymphomas compared with the general population, Indeed, primary testicular lymphoma accounts for about 1% of all lymphomas. We present a case of RA with primary testicular lymphoma treated with rituximab. A 67-year-o1d man was admitted due to aggravated polyarthralgia and morning stiffness. hIe was diagnosed testicular diffuse large B cell lymphoma (DLBCL) and done orchidectomy last year. There was no adjuvant chemotherapy nor radiotherapy because of patient's loss. Abdominal computed tomography (CT)scan showed about 6x4cm mass on the left adrenal gland. Malignant lymphoma (DLBCL) was proven by CT guided needle biopsy and he was treated with CHOP (cyclophosphamide, hydroxydaunorubicine, oncovin, prednisone) and rituximab (375㎎/㎡) combination regimen. After two cycle treatment, the clinical symptoms and laboratory data improved.

젊은 성인에서 흡연에 의한 상완동맥 내피기능의 부전에 관한 연구

이상철,권영주,방덕원,이선해,이보영,김지욱,김영훈,온영근,현민수,김성구 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

Background and Objectives : Cigarette smoking is a major factor and the most modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherosclerosis, before the structural change of the systemic arteries. We hypothesized that endothelial dysfunction might be present in the systemic arteries of young adult smokers and that this might be dose-dependent phenomenon. Therefore, we try to certify that smoking is associated with endothelial dysfunction in healthy young adults without other risk factor of atherosclerosis. Subjects and Methods : we studied noninvasively 29 subjects aged 3 to 4 decades without other risk factor of atherosclerosis, they were composed of the two groups, current smokers(n=15) and nonsmokers(n=14). Smoking history varied from 3 to 20 pack years. Using high-resolution ultrasound, vessel diameter and mean flow rate were measured at rest, during reactive hyperemia(with flow-mediated endothelium-dependent dilation), and after sublingual nitroglycerin(NG-induced endothelium-independent vasodilation). Result : Flow mediated endothelium dependent dilation was observed in the control subjects (9.4±3.44%) but was impaired in the smokers(5.8±2.51%)(p=0.004). NG-induced endothelium independent dilation is no difference in all subjects. Conclusion : Cigarette smoking is associated with endothelial dysfunction in healthy young adults.

L1 Transfer in L2 Relative Clause Attachment

Ji Hyon Kim 한국영어학학회 2010 영어학연구 Vol.16 No.3

The present study investigates an effect of L1 transfer in L2 comprehension through an off-line experiment examining how Korean L2 learners of English interpret ambiguous sentences containing relative clauses. Results from the experiment show that while English is known to be a low attachment (LA) language (Cuetos & Mitchell 1988; Carreiras & Clifton 1999), the group of Korean L2 learners showed a strong high attachment (HA) preference, suggesting that the relative clause (RC) attachment of the L1, Korean, was transferred to the L2. Although there was a slight tendency toward a positive correlation between L2 proficiency and L2 relative clause attachment preference, the correlation only neared significance. I suggest that although L2 proficiency may be a factor that affects the interpretation of the ambiguous relative clause construction, the effects of L1 transfer are strong enough to override this factor.

The influence of sentence complexity and working memory on relative clause ambiguity resolution

Ji Hyon Kim 한국외국어대학교 외국어 종합연구센터 언어연구소 2010 언어와 언어학 Vol.0 No.48

The present study aims to investigate the influence of sentence complexity on the relative clause ambiguity resolution preferences of native English speakers through the manipulation of three factors: relative clause length, relative clause position, and relative pronoun extraction site. The results of an offline questionnaire probing relative clause attachment preferences found significant effects of relative clause length and position, suggesting that syntactic complexity is a factor that influences ambiguity resolution strategies within a language. In addition, the influence of individual working memory capacity on relative clause processing was also examined, with the results showing a significant negative correlation between working memory capacity and relative clause attachment preference