Tetracycline 처리된 차폐막이 치은 섬유아세포에 미치는 영향

심재창,김영준,정현주,박병주 전남대학교 치과대학 1999 전남치대논문집 Vol.11 No.1

The purpose of this study was to evaluate the effect of tetracycline-treated e-PTFE membrane on the human gingival fibroblast attachment. To evaluate the cell attachment to membrane, the number of gingival fibroblast attached to e-PTFE membrane was counted by hemocytometer. Also the cytotoxic effect of tetracycline-treated e-PTFE membrane on human gingival fibroblast was measured by Wataha's MTT assay. After tetracycline-treated barrier membrane was exposed to culture media for 24 hours, cell attaachment to membrane and cytotoxic effect were measured. The results were as follows; As for cell proliferation rate, total cell number increase in both control group and tetracycline-treated e-PTFE membrane in course of time, but the cell numbers were decreased to half in tetracycline-treated barrier membrane as in the control group. In MTT assay, tetracycline-treated e-PTFE membrane showed moderate to weak cytotoxic effect compared to non-treated control. At the begining, tetracycline-treated, so was barrier membrane released abundant tetracycline and so decreased the number of cell attached barrier membrane, but not almost observed cellular activity inhibition on attached cell and as decreasing tetracycline-treated barrier membrane, the number of attached cell were increased. These results might suggest that tetracycline-treated e-PTFE membrane showed relatively low proliferation rate of attached cells, but weak cytotoxic effect. So it is suggested tetracycline-treated e-PTFE membrane could bind gingival connective tissue normally and the healing site could gain stability.

모바일로봇 장애물회피 제어

심병균,Nguyen Huu Cong,김준홍,조창제,한성현 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

This paper achieves a research about avoidance of obstacles avoidance based on ultrasonic sensor. The performance of the proposed obstacle avoidance robot controller in order to determine the exact dynamic systems modeling system that uncertainty is difficult for nomadic controlled robot direction angle by ultrasonic sensors throughout controlled performance tests. In additionally, this study is an in different ways than the self-driving simulator in the development of ultrasonic sensors and unmanned remote control techniques used by the self-driving robot controlled driving through an unmanned remote controlled unmanned realize the performance of factory automation.

핸드볼 페널티드로우 시 숙련자와 비숙련자 간의 시각적 변이 비교 분석

한재희,박영민,신선미,이준희,심윤식 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

The purpose of this study is to analyze the visual variation of skilled and unskilled people, and to obtain data necessary for skill improvement of effective handball penalty throw. An eye tracker was used to collect eye movements, concentration points, directions, and paths during penalty throws. The results are as follows: 1) For skilled players, the place where they threw and the place where their eyes were focused matched. 2) There is no difference in the presence or absence of eye contact with the goalkeeper.

전기자극이 성견 골결손부에 매식된 임플란트 주위조직의 치유에 미치는 영향

심재창,김영준,김옥수,정현주 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.2

Several experimental studies showed that the application of small amounts of electric current to bone stimulated osteogenesis at the site of the cathode and suggested that electrical currents promote osseointegration around dental implants. The purpose of this study was to determine the effect of direct microcurrent to endosseous titanium implants placed in bone defects. The right and left 2nd, 3rd and 4th mandibular premolars in ten mongrel dogs (15kg of weight) were extracted. One month later, Ti-machined screw type implants(3.8 mm diameter×8.5 mm length, AVANA�, Ostem) were placed in surgically created circumferential defect area(width 5mm, depth 4mm). The implants were divided into three groups according to the treatment modalities: Control group- implants without electrical stimulation; Experimental group I- implants with allogenic demineralized freeze dried bone grafting and Experimental group Ⅱ- implants allogenic demineralized freeze dried bone grafting and electric stimulation. The animals were sacrificed in the 4th and 8th week after implant placement and un-decalcified specimens were prepared for histological and histometrical evaluation of bone-implant contact ratio (BIC) and bone formation area ratio (BFA) in defect area. Some specimens at 8 weeks after implantation were used for removal torque testing. Histologically, there were connective tissue infiltration in the coronal part of defect area in control and the experimental group I. whereas direct bone contact was found in the experimental group Ⅱ without connective tissue invasion. Average BIC ratios at 4 weeks of healing were 60.1% in the experimental group Ⅱ, 47.4% in the experimental group I and 42.7% in the control. Average BIC ratios at 8 weeks after implantation were 67.6% in the experimental group Ⅱ, 55.9% in the experimental group I and 54,6% in the control. The average BFA ratio was 84.0% in the experimental group Ⅱ, 71.8% in the experimental group I and 58.8% in the control at 4 weeks, and the BFA ratios were 89.6% in the experimental group Ⅱ, 81.4% in the experimental group I and 70.5% in the control at 8 weeks after implantation. The experimental group Ⅱ showed also significantly greater BIC and BFA ratios compared to the control and the experimental group I (p<0.05). The removal torque values at 8 weeks after implantation were 56 Ncm in the experimental group Ⅱ, 49 Ncm in the experimental group I and 43 Ncm in the control. There was a statistically significant difference among 3 groups(p<0.05) . These results suggest that electrical stimulation improve and accelerate bone healing around endosseous titanium implants in bone defect.

창의력 향상을 위한 WBI 시스템 구현 및 평가

심재권,전호실,박기홍 군산대학교 정보통신기술연구소 2000 情報通信技術硏究論文集 Vol.4 No.-

This thesis present implementation of a WBI system for creativity development of the elementary school student in the training activity through web. A proposed system consists of made up a learner module and a manager module. The learner module helps the training activity for developing fluency, flexibility and originality, and the manager module helps and appraises the training activity of the learner. This WBI system is the embodiment of already established creativity development program on th Web. It is anticipated that this system is the model applying the advantage of the Internet to the education and training field in effectiveness.

종골 골절 치료에 있어서의 전산화 단층 촬영의 유용성

김학준,하권익,윤정로,심재익,김택선,김영배,이우승,최재혁 대한골절학회 2003 대한골절학회지 Vol.16 No.4

이형성 신장과 동반된 이소성 요관

김재헌,한민철,박성재,정준호,심봉석,조민선 이화여자대학교 의과대학 2005 EMJ (Ewha medical journal) Vol.28 No.1

Ectopic ureteral orifice presents predominantly in young girls with duplicated kidneys and ureters, and mostly drains from ectopic ureters were associated with non-duplicated upper urinary systems and it is called a single system ectopic ureter. It is frequently associated with renal dysplasia or agenesis and ureterocele. Compared with ectopic ureter draining from the duplicated kidney, the diagnosis of single system ectopic ureter is often delayed because the ectopic ureter may be associated with a single small dysplastic, poorly functioning kidney. We report a case of single system ectopic ureter associated with dysplastic and poorly functioning kidney.

지역사회획득 폐렴의 치료지침 권고안

송재훈,정기석,강문원,김도진,배현주,서지영,심태선,안중현,안철민,우준희,이남용,이동건,이미숙,이상무,이영선,이혁민,정두련,지역사회획득 폐렴 치료지침 제정위원회 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

A successful therapy of community-acquired pneumonia requires appropriate empirical antimicrobial therapy. Etiology and antimicrobial susceptibility of major pathogens of pneumonia can differ by country. Therefore, an ideal treatment guideline of community-acquired pneumonia should be based on the studies performed in each country. We developed a treatment guideline for community-acquired pneumonia in immunocompetent adults in Korea. This guideline was developed by the joint committee of the Korean Society for Chemotherapy, the Korean Society of Infectious Diseases, and the Korean Academy of Tuberculosis and Respiratory diseases.

쇄골 중간부 골절후 불유합 및 지연 유합의 원인

윤정로,심재익,김택선,이성종,김영배,김학준,안국환,장재영,홍명표 대한골절학회 2002 대한골절학회지 Vol.15 No.4

쇄골 중간 1/3 부위의 골절은 치료 결과가 양호하여 보존적 치료가 원칙적으로 받아 들어지고 잇으며 불유합에 대한 빈도도 낮은 것으로 되어 있다. 그러나 최근 전위 및 단축의 정도가 심할 경우 높은 불유합의 결과와 불량한 임상 결과를 보고하고 있어 이런 예에 대해선 수술적 치료를 권장하고 있다. 저자들은 단축 및 전위의 정도와 불유합의 연관성을 알아보고자 하였다. 연구 대상 및 방법 : 1993년 2월부터 2002년 1월까지 본원에 내원 했던 성인 중간부 쇄골 골절 환자 194명 중 완전 전위를 보인 78례를 조사하여 이중 63례를 대상으로 분석하여 후 향적 연구를 시행하였다. 4개월 추시 후에도 방사성 사진상 유합 소견이 관찰되지 않으면 불유합의 유의성을 알아보고자 하였다. 결 과 : 63례 중 불유합 및 지연 유합을 소견을 보인 환자는 15(23%)례였다. 골유합을 보인 48례의 단축은 평균 8.6㎜(2㎜-17㎜)였고, 전위는 평균 9.7㎜(2-22㎜)였다 .불유합 및 지연 유합을 보였던 15례에서 단축은 평균 14.5㎜(3㎜-37㎜), 전위는 평균 17.3㎜(4-25㎜)였다. 18㎜이상 단축이 있었던 경우 불유합의 발생과는 통계학적으로 유의성을 나타내었고(Fisher's exact test, p<0.01), Chi-square test상 16㎜ 이상의 전위를 보였던 경우 불유합 발생과 통계학적으로 의미가 있었다(p<0.01). 결 론 : 쇄골 골절 특히 중간 1/3의 골절은 비교적 보존적 치료에 결과가 좋은 것으로 되어 있으나, 전위 및 단축이 심한 경우 불유합에 대한 가능성이 높이 때문에 보다 경과 관찰시 유합의 진행이 없으면 적극적인 치료를 고려해야한다. Purpose : Because the prognosis of the mid 1.3 clavicle fracture is good, the conservative treatment with a figure of 8 bandage is the gold standard and the nonunions are rare. However, recently surgical treatment is recommended when the shortening and displacement is severe because of the high nonunion rate and the poor clinical result. This study was undertaken to evaluate that the shortening and displacement at fracture site are associated with the development of nonunion. Materials and Methods : We analysed the 194 fractures of mid 1/3 clavicle in adults which had been treated conservatively from February 1993 to January 2002 and did the retrospective study. Of these, 78 cases were originally in the middle third of the clavicle and had been completely displaced. We reviewed 63 of these cases. The shortening and displacement at the fracture site was measured on the initial roentgenogram. And the analysis of the patients' chart was done for another predisposing nonunion factors. Nonunion and delayed union are considered to be present when there has been little or no progression of clinical or radiographic healing at a minimum of 4 months after injury. Results : 15 of the 63 cases had developed nonunion.. The average 8.6㎜(2㎜-17㎜) shortening and average 9.7㎜(2-22㎜) in the union patients. The average 14.5㎜(3㎜-37㎜) shortening and average 17.3㎜(4-25㎜) in the nonunion patients. We found that initial shortening ≥18㎜(Fisher's exact test, p<0.01) and initial displacement ≥ 16㎜(Chi-square test. p<0.01)at the fracture site were significantly associated with the development of nonunion. Conclusion : The conservative treatment with figure-80-bandage is the gold standard in the clavicle middle one third fracture. However, the nonunion is commonly occurs in the cases of more of severely shortened and displaced fractures. If there are no signs of callus formation and the patient complains of pain after several week, osteosynthesis should be considered.

포도종실 추출물이 Methylcellulose 필름 성질에 미치는 영향

유승모,박준서,정하열,심재용,김병호,박장우 한국산업식품공학회 2003 산업 식품공학 Vol.7 No.4

The film with methylcellulose(MC) and grape seed extract(GSE) were prepared by casting their aqueous solution at 80℃ and drying at 23℃ for 48 hrs. Effect of grape seed extract(GSE) on the barrier permeabilities and the thermomechanical property of methylcellulose(MC) film was studied. The barrier permeabilities and the thermomechanical property of MC film containing various contents of GSE were evaluated in terms of water vapor, oxygen permeabilities, and dynamic mechanical analysis(DMA). The rate of water vapor permeability of MC film decreased with GSE contnets in the MC films. Also, the rate of oxygen permeability also decreased with GSE contents indicating higher oxygen barrier property of MC film. The results showed that GSE had a good miscibility with MC and acted as a plasticizer for MC film resuling in lowering the glass transition temperature of the film.