간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

광 대역 무선/이동 멀티미디어 전송을 위한 기반 기술에 관한 연구

정재윤 慶北專門大學 2003 慶北專門大學 論文集 Vol.22 No.-

This paper propose the modified interference cancellation scheme to overcome MAI in DS-CDMA. Among ICs(Interference Cancellers), PIC(Parallel IC) requires the more complexity, and SIC(Successive IC) faces the problems of the long delay time. Most of all, the adaptive detector achieves good BER performance using the adaptive filter conducted iteration algorithm. so it requires many iterations. To resolve the problems, this paper propose an improved adaptive detector that the received signal removed MAI through the sorting scheme and the cancellation method are fed into the adaptive filter. Because the improved input signal is fed into the adaptive filter, it has the same BER performance only using smaller iterations than the conventional adaptive detector, and the proposed detector having adaptive filter requires less complexity than the other detectors.

혈액투석 환자에게서 발생한 재생불량성 빈혈 1예

정지용,윤나라,강대웅,오종찬,장재현,선길홍,박경희,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Aplastic anemia is a disease characterized by pancytopenia in the peripheral blood and hypocellular bone marrow with the fatty infiltration. The causes of the acquired aplastic anemia were usually related to drugs and immune-related diseases. A 34-years old man was admitted due to general weakness. He has been going hemodialysis for 2 years because of end stage renal disease (ESRD) due to chronic glomerulonephritis. At admission, laboratory tests showed hemoglobin 6.2 g/dL, hematocrit 18.0 %, WBC 5,710mm (neutrophil 71.8%, lymphocyte 19.1%, monocyte 5.9%), reticulocyte 1.9%, platelet 93,000/mm, Fe 12.8 ug/dL, TIBC 204 ug/dL, ferritin 941.47 ng /ml, haptoglobin 0.72 g/L, vitamin B12 508.17 pmol/L, folate 24 ng/mL, total protein 6.54 g/dL, albumin 3.76 g/dL, Alk. pohsphatase 79 IU/L, AST 30.0 IU/L, ALT 39.7 IU/L, total bilirubin 0.57 mg/dl, BUN 79.4 mg/dl and creatinine 10.18 mg/dl. Peripheral blood smear showed the normocytic normochromic anemia with anisocytosis. Anemia was diagnosed but it was irresponsive to the recombinant human erythropoietin (EPO) and blood transfusion. In the bone marrow aspiration smear were there the hypoplastic myeloid and erythroid precursors. The bone marrow biopsy section showed the hypoplasia of all components (10-20%) and the fatty infiltration. We have experienced one case of the idiopathic aplastic anemia in a patient going through hemodialysis and we just report it with documentary records. 저자들은 혈액 투석 중인 환자에서 약물, 면역계 이상등의 원인을 발견할 수 없었음에도 재생 불량성 빈혈이 발생한 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다.

라운드 리클라이너 개발을 위한 정적 강도 해석 및 안전성 평가

정윤구,임재규,김형종 江原大學校 産業技術硏究所 2004 産業技術硏究 Vol.24 No.A

Seat is one of the most important part of an automobile for passenger's safety especially when an accident happens. A recliner is a part of the seat assembly, having the function of adjusting the back-plate angle of a seat. Recently, many kinds of vehicles have adopted the round recliner module rather than the conventional types of recliners because of its broad compatibility and structural simplicity. In this study a two-dimensional finite element strength analysis has been performed using a commercial code ABAQUS/Standard for the purpose of developing a new round recliner model. The loading condition for the analysis is the same as the FMVSS 301 regulation. The finite element result for the round recliner has been compared with that for the conventional type.

일시적인 피질맹과 인지기능장애로 발현한 간성 뇌병증 1예

윤고운,박민정,박경원,차재관,김재우 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

A 55-year-old woman presented with transient cortical blindness and multiple cognitive impairments as initial symptoms of hepatic encephalopathy. Her past history was negative for chronic liver disease or gastrointestinal bleeding. Neurologic examinations showed bilateral visual loss with a normal pupillary reflex to light and neuropsychological test showed significant impairments in all cognitive domains. Laboratory tests revealed increased liver enzymes, ammonia level, and positive IgG HbcAb. Ultrsonography of the liver showed findings consistent with liver cirrhosis with splenomegaly. The visual evoked potential study resulted in no wave formation on both sides. T1-weighted brain MRI showed high signal intensity lesions in both globus pallidus and cerebral peduncles of the midbrain. After treatment with lactulose, cortical blindness and cognitive dysfunctions disappeared within several days. In rare cases of hepatic encephalopathy, cortical blindness with cognitive impairments may occur before alteration of consciousness and usually recovers following treatment of the hepatic encephalopathy.

공복 시 Caffeine 투여 후 일회성 운동이 흰쥐의 인슐린 및 골격근의 GLUT-4 발현에 미치는 영향

정일규,오명진,김영표,김종오,윤재석,서태범,윤진환 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

This study was done to investigate the effects of caffeine ingestion on the expression of GLUT-4 in rats' skeletal muscle(soleus m) and blood insulin level after 12 hr fasting condition and one hour treadmill running. Total 19 rats(Sprague-Dawley) who were 7week Did were used for experimental subjects and raised for 1week in the room controled the air temperature and relative humudity(22℃ and 50%). They were divided three groups ; 12hr fasting group(F group, n=5), fasting+exercise group(FE, n= 7) and fasting+caffeine+exercise group(FCE group, n=7). FG and FCE group performed treadmill running for one hour and the treadmill speed was 18m/min that was supposed to be moderate exercise to rats. Each Dr rats in FCE group was forced to he given the caffeine solution(5mg/kg, Sigma Chemical co.) through stainless steel tube directly to their stomachs one hour before treadmill exercise. Immediately after treadmill running, we anesthetized them with the mixed solution(Ketamin 80g/kg and Rompun 5ml/kg) to draw 3ml blood from heart four insulin analysis and then obtained the rats' soleus muscle for GLUT-4 expression. We found that FCE group showed significantly higher GLUT - expression then the other groups and FE group showed the lowest GLUT-4 expression. This rusults suggest that the endurance type of exercise in fasting condition inhibit the GLUT-4 expression in working muscle and the caffeine helped to facilitate the GLUT-4 expression during endurance type of exercise. The future studies needed to confirm the action of caffeine to increase the GLUT- 4 and the mechanism.

양측 하악과두 골절에 대한 관혈적 정보술후 나타난 근약화와 시력장애 : 증례보고

정기훈,신용길,김태열,신재명,윤규호,전인성 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.6

The condylar fracture show high occurrence rate in the following of symphysis and angle, because it is easy to have concentration of outer pressure due to its long and narrow anatomical shape and mouth opened state when trauma is attacked. For the clinical findings, there are trismus, opening deviation, mal-occlusion and open bite The classification of condylar fracture is varied due to the location of condylar bone fragment, fracture site. There are conservative and surgical methods for treatment modalities. Because of many advantages, conservative method is widely used it has no particular limits of treatment adjustment but the cases of absolutely surgical correction indication are easily found in clinical experience. Although many methods are suggested for treatments of condylar fracture, there are no particular surgical methods for precise reduction due to difficult accessibility in high condylar neck fracture. For precise reduction of condyle, we used Nam's method. However, in Nam's method, because condyle is fixed when once it is kept off externally reduced in avascular state, so complication such as condyle resorption is pointed out as a problem. In our clinic, we obtained some knowledge by treating a patient who had muscle weakness and vision disorder after temporary airway obstruction follownig the both condylar fracure operated using Nam's method, so here we reported the case with a study of documents.

오이의 品種 및 臺木의 種類에 따른 溢泌量, 無機成分 및 植物호르몬의 含量

鄭淳宰,申允燮,具禹書 東亞大學校生命資源科學大學附設 農業資源硏究所 1992 農業生命資援硏究 Vol.1 No.1

臺木의 種類 및 오이品種의 溢泌現象 및 無機成分과 식물 hormone 含量에 關하여 硏究하엿던 바 그 主要結果는 다음과 같이 要約될 수 있다. 1. 溢泌液의 量 및 經時的인 變化를 보면 接木오이가 自根오이보다 顯著히 높아 臺木의 效果가 뚜렷하였으며 自根苗에서는 四葉오이가, 接木苗에서는 四葉오이를 黑種호박에 接木한 苗에서 增加되었다. 經時的인 變化는 接木, 自根 共히 最初의 1時間 採取時에 가장 많았고 時間이 經過함에 따라 低下하였다. 2 .溢泌液內의 無機物含量은 수세미와 黑種호박에서 K, Ca, Mg含量이 높았고 만춘청장마디오이와 四葉오이는 接木에 依해 K와 Ca의 含量이 增加되었으나, 溢泌液內의 無機物의 含量과 臺木의 生育促進效果와는 特定한 關係가 있다고는 判斷되지 않는다. 3. 溢泌液으로부터 Cytokinine과 Gibberellin을 抽出할 수 있었는데 Bioassays에 依해 檢出된 Gibberellin含量은 臺木의 接穗促進效果와도 關係가 있을 것으로 推定되었으나 Cytokinine含量에서는 特定한 傾向을 찾아볼 수 없었다 Studies were conducted to investigate the xylem sap exudation phenomena, mineral element contents and endogenous plant hormones in cucumber cultivars and different rootstocks. The major results can be summarized as follows. 1. The amount of xylem sap exudated from the basal cut stem were significantly influenced by cucumber cultivars and kind of rootstock. Among the tested cucumber cultivars, ‘Sayeup’ showed the largest amount of xylem sap. ‘Heukzong’ rootstock also showed the largest amount of xylem sap among the tested rootstocks. The amount of xylem sap exudation was largest in the first hour of cut and gradually decreased with time after cutting. 2. The contents of K, Ca and Mg were higher in the xylem sap of ‘Susemi’ and ‘Heukzong’ rootstocks contents of K and Ca in ‘Manchoon Chungjang-madi’ and ‘Sayeup’ Cucumber were also increased by grafting. The contents of mineral elements in xylem sap of rootstocks could not be correlated with the growth promotion effect of the rootstocks. 3. Contents of gibberellin-like substance in xylem sap of rootstocks seemed to have some relationship on its growth promotive effect of the scion by rootstocks. Cytokinins were also extracted but their role in scion growth is yet to be clarified.

Bovine botulism outbreak associated with incidental consumption of presumably contaminated leftover food

( Jae Won Byun ),( Kyung Hyun Lee ),( Ha Young Kim ),( Soon Seek Yoon ),( Ji Youl Jung1 ),( Woo Seog Jeong1 ),( Jae Ku Oem ),( Jong Soo Lim ),( Myoung Heon Lee ),( You Chan Bae ) 한국예방수의학회(구 한국수의공중보건학회) 2013 예방수의학회지 Vol.37 No.1

Nine cattle among 18 in a native Korean herd died or were euthanized within 3 days. The affected cattle showed cowshed. The pigs and dogs had been fed leftover food originating from nearby restaurants, and the cattle could presumably reach the contaminated food in the pig troughs. Necropsy revealed a few chicken bones and red pepper pieces as well as large amounts of grain and rice straw hay mixed in the rumen. Botulism type D was isolated in the ruminal contents of one of the cattle. We speculated that the outbreak was associated with the cattle incidentally eating presumably contaminated leftover food from the pig trough.

자궁경부 상피종양에서 human papillomavirus 감염과 survivin 발현

윤재호,정동준,이정은,박동명,배동한,선우재근,백무준,김창진 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Human papillomavirus (HPV) has been considered a causative agent of uterine cervical carcinoma. HPV is a DNA oncogenic virus, which is well known as a causative virus in uterine cervical carcinoma. The virus is classified into two groups genotypically, low risk and high risk, according to the carcinogenic potentiality, and the determination of the viral genotype is important in clinical practice. Recently, numerous genotypes can be determined by high throughput method using DNA chip. Survivin is a recently characterized inhibitor of anti-apoptosis (IAP) protein, which is abundantly expressed in most solid and hematological malignancies, but undetectable in normal adult tissues. In this study, HPV genotypes are determined by DNA chip and the expression of survivin was examined by immunohistochemistry in 80 cases of uterine cervical intraepithelial neoplasia (CIN) and invasive carcinoma to see the roles of HPV and survivin in the carciogenesis of uterine cervical epithelial neoplasia. The results were as follows: 1. HPV positive rate was 72.5%, while negative rate was 27.5% in 80 cases of CIN and invasive carcinoma. The CIN and invasive carcinoma showed higher HPV positive rate (p <0.05). 2. HPV positive rate according to the histologic grade were 60%, 65%, 77% and 90% in CINI, CINII, CINII and invasive carcinoma, respectively. HPV positive rate showed increasing tendency according to the histologic grade, though there was no statistical significance. 3. The most frequent genotype was type 16 and the next were 58, 52, 18 and 33 in order of frequency. 4. Survivin was expressed in 96.3% of CIN and invasive carcinoma. The expression rate of survivin showed no significant difference between the histologic grade of CIN and invasive carcinoma, but showed tendency of increased expression rate in invasive carcinoma. 5. Survivin was expressed in HPV positive and in HPV negative each as in 95.5% and 96.6% respectively. There was no significant difference of survivin expression between HPV positive and negative cases. The above results suggest that HPV has no effect on the regulation of survivin expresson level in the uterine cervical intraepithelial neoplasia and invasive carcinomas.