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      • 레토르트파우치 튀김어묵의 熱處理條件에 關한 硏究 : 2. 熱處理條件과 Cook-value

        河璡桓,李應昊,金珍洙,具在根 제주대학교 1991 논문집 Vol.33 No.-

        魚肉煉製品은 最近 그 生産量이 急增하고 있으나 AF-2등 食品防腐劑의 使用이 전면 禁止됨에 따라 재래식 方法으로 만든 어묵은 유통에 상당한 어려움을 겪고 있다. 本 硏究는 이를 解決하기 위한 方案의 하나로 營養的 및 官能的인 品質의 低下를 最少化할 수 있는 高溫熱處理條件을 찾고자 하였다. 즉 熱處理時間은 F。값 6을 基準으로 하고 레토르트파우치 튀김어묵의 크기와 熱處理溫度를 달리 하였을 때의 品質을 C값을 利用하여 檢討하였다. 그 結果를 要約하면 다음과 같다. Fourier數의 性質과 같이 熱處理溫度가 높을수록 그리고 製品의 직경이 작을수록 熱處理時間을 短縮할 수 있었으며 熱處理溫度가 製品의 직경보다 熱處理時間을 短縮시키는데 더 크게 影響을 미쳤다. 製品의 中心, 表面 그리고 體積平均 C값은 모두 직경이 가장 작은 12㎜의 것이 제일 적었고 직경이 가장 큰 31㎜의 것은 제일 컸으며 이 경향은 熱處理溫度가 높을수록 뚜렸하였다. C값은 前報에서의 結果와 잘 一致하여 레토르트파우치 튀김어묵의 品質을 評價하는 좋은 理論的 指標가 될 수 있었으며 직경이 16㎜ 혹은 그 以下의 것은 高溫短時間熱處理로 品質低下를 最少化할 수 있었다. The fish meat paste products are rapidly growing in its production. However, the recent prohibition of AF-2 gives a lot of difficulties in the marketing of fish meat paste products manufactured by conventional procedures. The present study aims to obtain the thermal treatment conditions for minimizing the quality deterioration of the fish meat paste products. The fried fish meat paste was sealed in the retort pouches and treated by heat under the condition which the F。-value designated to 6. The influences of the thermal treatment temperature (112,116,120 and 124℃) and the diameter of the products ( 12,16,23,27 and 31㎜) on the quality were investigated using the cook-value. The results are summarized as follow: Like as characteristics of Fourier number, the thermal treatment time was shortened with higher temperature and smaller diameter. The increase in temperature influenced more effectively to shortening the thermal treatment time than decrease in the diameter of the products. The products with 12㎜ in diameter marked the lowest cook-values of center, surface and volume average in all and those with 31㎜ the highest values. From the results described above and in previous work, cook-values could be extensively used in the determination of quality of the fried fish meat paste products since those values conincided well with other practical values such as jelly strength, texture, color values and in vitro protein digestibility. It was concoluded that the fried fish meat paste products with 16㎜ or less in diameter which were thermally treated at higher temperature could minimize quality deterioration.

      • KCI등재

        산재보상을 신청한 뇌심혈관질환의 특성 분석

        유재홍,하은희,김수근,김정연,김용규,이의철,이철호,손준석 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.1

        목적: 이 연구는 뇌 · 심혈관 질환으로 업무상재해를 신청한 사례 중에서 승인된 사례와 불승인된 사례의 특성을 비교하여 뇌 · 심혈관 질환의 업무상 재해여부를 판단하는데 필요한 기초 자료를 제공하고자 한다. 방법: 2000년부터 2004년까지 근로복지공단에 업무상 재해로 요양이 신청되어 승인여부가 결정된 뇌 · 심혈관 질환자 12,309명을 대상으로 하였다. 승인여부와 관련된 특성을 확인하기 위해 연도별, 업종별, 규모별, 직업별, 성별, 연령별, 질환별, 생존유무별 그리고 기존질환 유무에 대하여 카이제곱 검정과 다변량 로지스틱 회귀분석을 이용하였다. 결과: 다변량 로지스틱 분석에서 뇌 · 심혈관 질환의 불승인에 대한 승인의 비차비는 광업을 기준으로 하였을 때에 전기가스 상수도업이 4.18(95% CI=1.43~12.17), 건설업이 2.39 (95% CI=1.22~4.69), 제조업이 2.10 (95% CI=1.08~4.07)이었고, 장치기계조작원 및 조립원에 비하여 서비스 근로자 및 상점과 시장 판매근로자 군이 1.90(95% CI=1.47~2.47), 전문가 군이 1.83(95% CI=1.50~2.23), 기술공 및 준전문가 군이 1.63(95% CI=1.35~1.97), 입법 공무원과 고위 임직원 및 관리자 군이 1.62(95% CI=1.24~2.12)이었고, 여성이 남성에 비하여 1.31(95% CI=1.13~1.53), 심장질환에 비하여 뇌혈관질환이 2.75(95% CI=2.42~3.13), 사망한 경우가 생존한 경우에 비하여 6.01(95% CI=4.89~7.38)이었다. 결론: 우리나라에서 뇌심혈관질환으로 업무상 재해를 신청하는 건수는 증가하고 있고 승인율은 비교적 높았으며 승인에 영향을 미치는 요인으로는 업종, 규모, 직종, 성, 연령, 질환, 생존유무 등이 확인되었다. 특히 업종과 직종에 따라서 승인율의 차이가 큰 것이 어떠한 요인의 영향 때문인지에 대한 검토가 필요하고, 특히 뇌실질내 출혈의 경우에 다른 질환에 비하여 승인율이 매우 높았던 것은 업무수행성에 대한 인정기준의 잘못된 적용의 결과 이므로 시정이 필요하겠다. Objectives: This study was performed to provide fundamental data to judge whether or not cerebro and cardiovascular diseases are work-related, by comparing the characteristics between approved and non-approved cases among the worker's compensation claims. Methods: We collected 12,309 cerebro and cardiovascular disease claims based on the worker's compensation records of the Labor Welfare Corporation from 2000 to 2004. The approved and non-approved cases were analyzed according to factors such as the calendar year, industry, company size, occupation, gender, age group, classification of cerebro and cardiovascular diseases, fatality and underlying diseases. We used x²-test and multivariate logistic regression for the analysis. Results: According to multivariate logistic regression, electricity gas and water supply (OR=4.18, 95% CI=1.43~12.17), construction (OR=2.39, 95% CI=1.22~4.69) and manufacturing (OR=2.10, 95% CI=1.08~4.07) industries had a higher approval rate than mining and quarrying industries. Service workers and sales & marketing department workers (OR=1.90, 95% CI=1.47~2.47), professionals (OR=1.83, 95% CI=1.50~2.23), technicians and associate professionals (OR=1.63, 95% CI=1.35~1.97) and legislators and senior officials and managers (OR=l.62, 95% CI=1.24~2.12) had a higher approval rate than plant and machine operators and assemblers. Female workers had a higher approval rate (OR=1.31, 95% CI=1.13~1.53) than male workers. Cerebrovascular diseases had a higher approval rate (OR=2.75, 95% CI=2.42~3.13) than cardiovascular diseases. Fatal cases had a higher approval rate (OR=6.01, 95% CI=4.89~7.38) than surviving cases. Conclusion: For cerebro and cardiovascular diseases, workers' compensation claims are increasing, approval rates are relatively high and factors such as industry, company size, occupation, gender and fatality are related. A remarkable difference in the approval rate was found according to industry and occupation, suggesting the need for further study to identify which factors influence the approval rate. The approval rate for intracerebral hemorrhage arising in the course of employment (COE) was significantly higher than that arising out of employment (AOE), suggesting the need to correct the approval criteria.

      • KCI등재

        한국인 직무 스트레스 측정도구의 개발 및 표준화

        장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

        Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

      • Proteome analysis of human stomach tissue : Separation of soluble proteins by two - dimensional polyacrylamide gel electrophoresis and identification by mass spectrometry

        Geun Hyoung Ha,Seung Uook Lee,Deok Gyeong Kang,Na-Young Ha,Soon Hee Kim,Jina Kim,Jong Min Bae,Jae Won Kim,Chang-Won Lee 한국생명과학회 2002 한국생명과학회 심포지움 Vol.38 No.-

        Two-dimensional gel electrophoresis (2-DE) maps for human stomach tissue proteins have been prepared by displaying the protein components of the tissue by 2-DE and identifying them using mass spectrometry. This will enable us to present an overview of the proteins expressed in human stomach tissues and lays the basis for subsequent comparative proteome analysis studies with gastric diseases such as gastric cancer. In this study, 2-DE maps of soluble fraction proteins were prepared on two gel images with partially overlapping pH ranges of 4-7 and 6-9. On the gels covering pH 4-7 and pH 6-9, about 900 and 600 protein spots were detected on silver staining, respectively. For protein identification, proteins spots on micropreparative gels stained by colloidal Coomassie Brilliant Blue G-250 were excised, digested in-gel with trypsin, and analyzed by peptide mass fingerprinting with delayed extraction-matrix assisted laser desorption/ionization-mass spectrometry (DE-MALDI-MS). In all, 243 protein spots (168 spots in acidic map and 75 spots in basic map) corresponding to 136 different proteins were identified. Besides these principal maps, maps of lower resolution, i.e. overview maps (displayed on pH 3-10 gels) for total homogenate and soluble fraction, are also presented with some identifications mapped on them. Based on the 2-DE maps presented in this study, a 2-DE database for human stomach tissue proteome has been constructed and available at http://proteome.gsnu.ac.kr/DB/2DPAGE/Stomach/. The 2-DE maps and the database resulting from this study will serve important resources for subsequent proteomic studies for analyzing the normal protein variability in healthy tissues and specific protein variations in diseased tissues.

      • SCIESCOPUSKCI등재

        Spin Dependent Transport Phenomena for Annealed Co46Al19O35 Granular Thin Films

        Jae-Geun Ha 한국자기학회 1998 Journal of Magnetics Vol.3 No.4

        I have overviewed the change in GMR on annealing, in conjunction with the change in microstructure. The Co_(46)Al_(19)O_(35) granular thin films were annealed at 300℃ for various annealing time to change the microstructure. The magnitude of GMR decreases considerably with increasing annealing time, although the size of Co granules estimated from TEM observation show a small change. Parameter fits of magnetization curves and magnetoresistance curves to the Langevin function suggest that large clusters consisting of several small Co granules, which are coupled ferromagnetically, are related with the decrease of GMR on annealing. The temperature dependence of electrical resistivity (p) shows the relationship of log p versus T^(-½) for the sample annealed for 10 min., 1 hr. and 6 hrs. However, the sample annealed for 38 hrs. shows the relationship of log p versus T^(-¼), which represents a significant change in the transport mechanism.

      • SCOPUSKCI등재

        Occurrence and characterization of oseltamivir-resistant influenza virus in children between 2007-2008 and 2008-2009 seasons

        Kim, Seoung Geun,Hwang, Yoon Ha,Shin, Yung Hae,Kim, Sung Won,Jung, Woo Sik,Kim, Sung Mi,Oh, Jae Min,Lee, Na Young,Kim, Mun Ju,Cho, Kyung Soon,Park, Yeon Gyeong,Min, Sang Kee,Lee, Chang Kyu,Kim, Jun Su The Korean Pediatric Society 2013 Clinical and Experimental Pediatrics (CEP) Vol.56 No.4

        Purpose: There was a global increase in the prevalence of oseltamivir-resistant influenza viruses during the 2007-2008 influenza season. This study was conducted to investigate the occurrence and characteristics of oseltamivir-resistant influenza viruses during the 2007-2008 and 2008-2009 influenza seasons among patients who were treated with oseltamivir (group A) and those that did not receive oseltamivir (group B). Methods: A prospective study was conducted on 321 pediatric patients who were hospitalized because of influenza during the 2007-2008 and 2008-2009 influenza seasons. Drug resistance tests were conducted on influenza viruses isolated from 91 patients. Results: There was no significant difference between the clinical characteristics of groups A and B during both seasons. Influenza A/H1N1, isolated from both groups A and B during the 2007-2008 and 2008-2009 periods, was not resistant to zanamivir. However, phenotypic analysis of the virus revealed a high oseltamivir $IC_{50}$ range and that H275Y substitution of the neuraminidase (NA) gene and partial variation of the hemagglutinin (HA) gene did not affect its antigenicity to the HA vaccine even though group A had a shorter hospitalization duration and fewer lower respiratory tract complications than group B. In addition, there was no significant difference in the clinical manifestations between oseltamivir-susceptible and oseltamivir-resistant strains of influenza A/H1N1. Conclusion: Establishment of guidelines to efficiently treat influenza with oseltamivir, a commonly used drug for treating influenza in Korean pediatric patients, and a treatment strategy with a new therapeutic agent is required.

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