HIV 감염자에 대한 달팽이 엑기스의 혈액면역학적 효과

조영걸,이희정,오원일,강은숙,김은순,김영봉,조양자,조군제 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.2

A unique sialic-acid-binding lectin from giant African snail Achatina fulica(AF) has a T cell mitogenicity. It was also noted that acetone extracts of AF have a anti-HIV effect in vitro. Thirty HIV-infected individuals(HIV+) were treated with AF extract(40% Chunho extract) for average 5. 5 months. Peripheral blood sampling and questionnaire were done every month after take. There was a significant decrease of WBC from 4 months after take. As a result, lymphocyte counts also decreased(P<0.01). However, there was a significant increase of CD4+T cell percentage from 1 month(P<0.01). The mean increase of CD4+T cell count was significant for first one month(39/pl)(P<0.05). Body weight also increased significantly(P<0.05). Over 90% HIV+ ex-pressed symptomatic improvement and wanted to be treated with AF extract continuously after the end of this study. In one HIV+ treated with AF for 19 months, the increases of CD4+T cell percentage and counts over 11 times after AF extract take were mean 67% and 85%, respectively, compared to baseline value. These data strongly suggest that aqueous AF extract has a immune enhancing effect on HN+.

간호실무에서 신봉이론(Espoused theories)에 대한 탐색적 연구

서문자,김혜숙,이은희,박영숙,조경숙,강현숙,임난영,김주현,이소우,조복희,이명하,지성애,하양숙,손영희,권성복,김희진,추진아 성인간호학회 2001 성인간호학회지 Vol.13 No.1

As a nursing practice involves nurses' actions in a specific context of health care, this study has focused on exploring the espoused theories in nursing practice within the action science perspectives, Espoused theories are the belief, principles, and rationale expressed by the practitioner as guiding her/his actions in a situation of practice. The data were analysed qualitatively and 25 elements of espoused theories of nursing action were identified and clustered into 6 categories. The 25 elements of espoused theories are as follows: The clinical nurse worked in wholistic and individual nursing, focussed on the patient's needed, comfort and supportive nursing (5 theories of nursing goal) ; excellent skills, knowledge based, assessment and data collection, explaining, educating or a scientific basis(6 theories of nursing intervention): advocacy, value oriented, treatment, account- ability and commitment(4 theories of nursing ethics) ; human respect. partnership, trust(3 theories of patient-nurse relationship) : knowledgable, accumulated clinical experiences and personally lived experiences. positive perspectives(4 theories of nurse), role of intervention. rewarding peer relationship(3 theories of situations) The above mentioned espoused theories are similar to that of nursing textbooks which students learned through basic nursing education and almost the same as the Acts ofa Nurse in Korean. However, we are doubtful whether nurses actually do as they think. Therefore. it is recommended to review the theories-in-use in order to and any discrepancies between the espoused theories and the reality of nursing actions

항암화학요법 관련 오심과 구토 완화를 위한 비약물요법에 관한 연구동향

소향숙,최자윤,조인숙,김영재,김지영,김애숙,김옥미,김춘심,김현오,설영애,안정옥,이애리,이영자 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: Purposes of this study were to understand the current trends on complementary therapy in relieving chemotherapy-induced nausea and vomiting and to suggest the future research direction. Method: Subjects were selected on CINAHL, MEDLINE, Korean Academy Data Base from 1980 to 2001 which used nausea, vomiting, chemotherapy and complementary therapy as key words in experimental studies. Eight korean articles and twenty-one international articles were analyzed in terms of general characteristics, research methods, and types of complementary therapy. Data were analyzed by using descriptive statistical methods. Result: Since 2000, researchers have more actively used complementary therapy. In subject characteristics, mean age was 35.5 years old, 45% of the researchers were performed with high level of incidence of chemotherapy induced vomiting, 14% of them set limit of consecutive cycle during research, and 65% of them did not comment the selecting criteria of sample. About 60% of them were designed post-test only control group: 35% used INV by Rhodes, 31% used Likert scale, and 24% used VAS for dependent variable. Muscle relaxation therapy was mostly applied for relief of nausea and vomiting. Conclusion: Further studies will be needed to control extrinsic variables affecting nausea and vomiting in research design and to accumulate evidence with studies applying various complementary therapies.

Geocrete와 규산액을 이용한 매립지 사면 침출수 누출제어

조재범,현재혁,나진성,김자영 충남대학교 환경문제연구소 2000 環境硏究 Vol.18 No.-

There are two strategies to cope with the troubles in landfill site after closure. The first method is active in a way that the wastes are dug up and the recyclable materials are reutilized, meanwhile the materials not recyclable are incinerated in order to minimize the volume of residues to be disposed of. The second method is rather passive and defensive in a way that the source of contamination, that is, buried wastes are not treated. Instead, the transport of leaking leachate and gases generated from the wastes are intercepted and controlled. In the study, as a passive way, the efficient leachate blocking process will be investigated, and how well geocrete and soluble sodium silicate can be utilized as a substitute to controls leachate leaking from landfill sidewall. In case of compression test, the strength of mixture ( I ) and (Ⅱ), even after 7 days' curing were higher than the criteria threshold (5 kg/cm2). Soaking in the acrid for 4 days and 7 days respectively, the compressive strength of the specimens reduced seriously. The toxicity of geocrete is not detected through the bioassay test, once it is mixed with sodium silicate and the complex is formed. The hydraulic conductivity of the mixtures even after 7 days' curing satisfied the threshold limit (1.0×10-7cm/s).

통합적 림프부종 간호중재 개발 연구

조명옥,정향미,전점이,손수경,우영자,노미영,박순옥 성인간호학회 2003 성인간호학회지 Vol.15 No.2

The purpose of this study was the development of a comprehensive nursing intervention program for the client with acute lymph stasis and stage I lymphedema. Method: The Quasi-experimental design using a non-equivalent control group was used. The subjects were 22 stroke patients with lymph stasis in the control group and 23 patients in the experimental group. The complex physical therapy of Casley-Smith was carried out to the control group for 0 hours, and comprehensive nursing intervention for the experimental group was carried out for 60 minutes. The data for this study was gathered from Feb. 2002 until June 2002 and pertains knowledge about lymphedema, self-care for managing lymphedema, and circumferences of affected limbs. Data was analyzed by mean, standard deviation, x^2-test. And t-test. Result: The changes in knowledge about lymphedema, self-care practices, and circumference of affected limbs after nursing intervention did not show significant differences between control group and experiment group. Conclusion : It can be concluded that comprehensive nursing intervention had more efficiency than complex physical therapy in the treatment of edema for stroke patients because of it’s simplicity and time saving. Thereby, the comprehensive nursing intervention program developed in this study would be a useful therapy for the clients with lymph stasis and early stage lymphedema.

자색고구마가 사염화탄소 투여에 의한 흰쥐의 간손상 보호에 미치는 영향

조영자,김현아,방미애,오용비,정병춘,문윤호,정우진 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.3

The purpose of this study was to investigate the effects of dietary purple sweet potato(lpomoea batatas) powder on serum lipid levels and antioxidative enzymes in normal and pretective effect on hepatotoxicity rats induced by carbon tetrachlolide. Four groups of rats (3-week-old inbred Sprague-Dawley male rats) were normal rats fed control diet(C)_(1) induced hepatotoxicity rats fed control diet(EC)_(1) normal rats fed purple sweet potato diet(P), and induced hepatotoxicity rats fed purple potato sweet diet(EP). Rats were induced by single injection of 50% carbon tetrachloide(0.1 mL/100 g B.W., i.p.). The rats were fed ad libitum each of the experimental diet for 5 weeks. After 5 weeks the rats were sacrificed and activities of antioxidant enzymes and lipid peroxidation products were determined in their liver homogenates. But serum concentrations of lipid was not significant in all groups. Serum alanine aminotransferase(ALT/GPT) and aspartate aminotransferase(ALT/GPT)of the EC and EP groups were heigher than the C and P groups. The hepatic glucose 6-phosphatase(G9Pase) activity of the group fed purple potato diet(P) was lower than the other groups(p<0.05). However, The glutathione peroxidase(GPx) activities was not statistically different between the groups. Renal glutathione S-transferase(GST) activity of the EC and EP groups were lower than the C and P groups(p<0.05). In conclusion, these results suggest that purple sweet potato is believed to be possible protective effect on hepatotoxicity rats induced by carbon tetrachlolide.

간장의 덧에서 분리한 Zygosaccharomyces rouxii BH-90과 Candida versatilies BH-91의 동정및 특성

조경자,박춘옥,채영주,김동석,류병호 慶星大學校 1993 論文集 Vol.14 No.2

This studies attempted to bred the two yeasts of highest level of alcohol and 4-ethylguaiacol production from fermented mash conventional soy sauce. Two kinds of yeast isolated from conventional fermented mash were identified and designated as Zugosaccharomyces rouxii BH-90 and candida versatilis BH-91 which produced the highest levels of ethyl alcohol and 4-ethylguaiacol. The two yeast strains preferred pH 5.0 and 30℃for highest levels of 2.5% ethylalcohol and 18mg/? 4-ethylgaicacol production.

식이 중 인동초를 섭취한 당뇨유발 흰쥐의 혈당 및 지질대사

조영자,김현아,방미애 목포대학교 생활과학연구소 2000 생활과학논집 Vol.3 No.-

The purpose of this study was to invesgate the effect of L. japonica tumbo(P) on blood glucose level and lipid metabolism in streptozotocin(STZ) induced diabetic rats. Male Sprague-Dawley rats weighing(180~200g)were divided into four groups: control(C), STZ-control(CD), and two experimental groups(P and PD). Diabetes mellitus were induced by single injection of the streptozotocin at tue dose of 60mg/kg B.W. The experimental groups were fed a AIN-76 recomendation diet mixed with the P powder(5%/kg diet). The diet and water were intake determined everyday. The blood glucose level was determined everyweek, and the serum cholesterol was determined every two weeks. After 5 weeks, the rats sacrificed and the blood glucose, serum cholesterol. triglyceride, HDL-cholesterol concentrations were determined. LDL-cholesterol concentrations was calculated by eqation. Diabetic rats showed the lower weight gain compared to the normal rats. The serum glucose level of PD was not lower than C group. However, the serum cholesterol, triglyceride and HDL-cholesterol level of CDI and PD group were heigher than C group. Diabetic rats showed that the hepartic glutathione reductase(GR) was sighificantly heigher than C group, but malondialdehyde level was significantly decreased. P supplymentation was reduced the hepartic malondialdehyde(MDA) level. The glutathione reductase(GR) and HDL-cholestrol level were increased in the diabetic experimental groups compared C group. In comculusion, showing the possibility of preventive and therpeutic use of the wild edible plant(Indong- Cho) to the diabetes mellitus.

림프부종 환자의 자가관리에 관한 실태 조사

조명옥,정향미,전점이,손수경,우영자,노미영,박순옥 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose : The purpose of this descriptive study was to gain basic data to develop a self-care protocol for the lymphedema patients. Method : The subjects of this study consisted of 115 patients with lymphedema from 8 hospitals and two community health and welfare centers in Busan and Seoul. The data was collected with questionnaire by self reporting of patients between March 2001 and December 2001. Data was analyzed by mean and percentage. Result : For self-care activities in daily life, compliance of 'use skin care preparations', 'use heat and cold', 'protect from local compression on affected limbs', 'protect from insect biting', 'use aids to protect affected limbs', 'take diuretics and take protein diet' did not reach to 50%. For self-care activities related to complex physical therapy, 28.7% of subjects complied with compression garment, 14.8% with manual lymph drainage and 13.0% with exercise, 20.0% of subjects tried to treat with acupuncture and 13.9% with heat therapy. Conclusion : From this study, it is suggested that patients need to get a self-care education with correct information about self care activities and health care professionals need to develop more convenience self-care techniques of massage and exercise.

뽕잎, 감초, 솔잎 및 당귀분말이 흰쥐의 혈청조성에 미치는 영향

조영자,허원녕 한국식생활문화학회 2005 韓國食生活文化學會誌 Vol.20 No.1

The purpose of this study was to investigate the effect of dietary Morus alba L.(Bong-ip, B), Glycyrrhizae glabra(Gam-chei, C), Pinus densiflora(Sol-Ip, S) and Angelica gigas(Dang-gi, D)powder on serum composition in rats(Sprague-Dawley male rats, 100-110g). Serum TG(triglyceride, p〈0.01), total cholesterol, glucose, total protein, albumin, GGT(y-glutamyl transferase, p〈0.05) were significantly increased D group than that of nomal and other groups. but UA(uric acid, p〈0.05) was significantly decreased, and C group(p〈0.05)was significantly increased. but C group of urine(p〈0.05)was significantly decreased. Also, B and S groups(p〈0.05) of BUN(blood urea nitrogen). S group(p〈0.05) of ALP(alkaline phosphokinase, B and C(p〈0.05) of CPK(creatinine phosphokinsae, p〈0.05) were significantly increased. B. S and C groups were better than D group for lipid metabolism. and pretection to liver. Also, B and C groups of glucose were same as normal diet. so Mows alba L. was good food for lipid metabolism and hypoglycemic effect.