Suppression of peroxisome proliferator-activated receptor gamma-coactivator-1alpha normalizes the glucolipotoxicity-induced decreased BETA2/NeuroD gene transcription and improved glucose tolerance in diabetic rats.

Kim, Ji-Won,You, Young-Hye,Ham, Dong-Sik,Cho, Jae-Hyoung,Ko, Seung-Hyun,Song, Ki-Ho,Son, Ho-Young,Suh-Kim, Haeyoung,Lee, In-Kyu,Yoon, Kun-Ho Association for the Study of Internal Secretions 2009 Endocrinology Vol.150 No.9

<P>Peroxisome proliferator-activated receptor gamma-coactivator-1alpha (PGC-1alpha) is significantly elevated in the islets of animal models of diabetes. However, the molecular mechanism has not been clarified. We investigated whether the suppression of PGC-1alpha expression protects against beta-cell dysfunction in vivo and determined the mechanism of action of PGC-1alpha in beta-cells. The studies were performed in glucolipotixicity-induced primary rat islets and INS-1 cells. In vitro and in vivo approaches using adenoviruses were used to evaluate the role of PGC-1alpha in glucolipotoxicity-associated beta-cell dysfunction. The expression of PGC-1alpha in cultured beta-cells increased gradually with glucolipotoxicity. The overexpression of PGC-1alpha also suppressed the expression of the insulin and beta-cell E-box transcription factor (BETA2/NeuroD) genes, which was reversed by PGC-1alpha small interfering RNA (siRNA). BETA2/NeuroD, p300-enhanced BETA2/NeuroD, and insulin transcriptional activities were significantly suppressed by Ad-PGC-1alpha but were rescued by Ad-siPGC-1alpha. PGC-1alpha binding at the glucocorticoid receptor site on the BETA2/NeuroD promoter increased in the presence of PGC-1alpha. Ad-siPGC-1alpha injection through the celiac arteries of 90% pancreatectomized diabetic rats improved their glucose tolerance and maintained their fasting insulin levels. The suppression of PGC-1alpha expression protects the glucolipotoxicity-induced beta-cell dysfunction in vivo and in vitro. A better understanding of the functions of molecules such as PGC-1alpha, which play key roles in intracellular fuel regulation, could herald a new era of the treatment of patients with type 2 diabetes mellitus by providing protection from glucolipotoxicity, which is an important cause of the development and progression of the disease.</P>

부산지역 수돗물과 지하수의 중금속 농도

김준연,손지언,김형수,김두희,원미숙,김인식,이혜령 동아대학교 산업의학연구소 2000 산업의학연구소 논총 Vol.- No.5

This study investigated mean airborne CO concention of 15 workplaces, suspected of CO exposure and conducted self-reported questionnaire completion and indirect COHb concentration measure using Micro II Smokerlyzer to healthy 702 adult subjects from 1999 May to 1999 September in order to find a relation of CO exposure and occupational factors, socioeconomic factors, and health related behaviors and confirm the related conditions in the screening test for CO exposure. The results of this study were summarized as follows : 1. In the CO exposed and non exposed group, COHb concentrations of the smokers were 2.55±0.96% and 2.21±0.97% and that got a statistically significant difference, There were not statistically significant differences in the age and total smoking index. Passed times after the last smoking, Working time/day, and working duration were statistically significant difference (p〈0.05). 2. In the CO exposed and non exposed group, COHb concentrations of non-smoking group were 0.94±0.35% and 0.68±0.47% and that got a statistically significant difference. There were not statistically significant differences in the age and working duration but Working time/day was a statistically significant difference(p〈0.05). 3. In the CO exposed group, r-square of multiple regression of the smokers was 38.5 % and passed time after the last smoking, working time/day, and job category were statistically significant differences (p〈0.05). And r-square in the CO non-exposed group was 38.3 % and age, passed time after the last smoking, and total smoking index were statistically significant difference. 4. In the CO exposed group, r-square of multiple repression of the non-smokers was 66.3% and job category and airborne CO concentration were statistically significant differences(p〈0.05). But r-square of non-smokers in the CO non-exposed group was 1.0% and there was not a statistically significant difference(p〈0.05). 5. In the smokers of CO exposed and non exposed groups, relation of COHb concentration and passed time after the last smoking was expressed as exponential function, Y = 2.9182e-0.0083x and r-square of this function was 37.4%. Therefore it was more than 150 minutes that passed time after the last smoking was when COHb concentrations were measured as less than 1%. In conclusion, variable, that was statistically significant to COHb concentraion in the both CO exposed and non-exposed smokers, was a passed time after the last smoking. We suggest that you have to restrict the smoking of smokers at least 150 minutes in the exposed and non exposed group before COHb concentration measure in order to exclude smoking effects

The Effect of Rosiglitazone on the Cell Proliferation and the Expressions of p27 and Skp2 in<i>Helicobacter pylori</i>Infected Human Gastric Epithelial Cells

Kim, Sung-Soo,Cho, Young-Seok,Kim, Hyung-Keun,Shin, Ok-Ran,Chae, Hiun-Suk,Choi, Myung-Gyu,Chung, In-Sik The Korean Society of Gastroenterology 2010 대한소화기학회지 Vol.55 No.4

<P>Background/Aims: Ligands for peroxisome proliferator-activated receptorgamma (PPARgamma), a member of the ligand-activated nuclear receptor superfamily, exhibit anti-tumoral effects and are associated with de novo synthesis of proteins involved in regulating the cell cycle and cell survival/death. Helicobacter pylori (H. pylori) is an etiologic agent for gastric adenocarcinoma, and raises the cell turnover of gastric epithelium. The aim of this study was to investigate the effect of PPARgamma ligand rosiglitazone on the cell proliferation and the expressions of p27 and Skp2 protein in H. pylori infected gastric epithelial cells. Methods: We examined the expression of PPARgamma by Western blot in H. pylori infected AGS human gastric epithelial cells. The effect of rosiglitazone on the survival of H. pylori infected AGS cells was assessed by cell viability assay. After the treatment of rosiglitazone in H. pylori infected AGS cells, the expressions of p27 and Skp2 were assessed by Western blot. Results: The expression of PPARgamma protein was increased in H. pylori infected AGS cells. Cell growth was inhibited and decreased in dose- and time- dependent manner in H. pylori infected AGS cells treated with rosiglitazone. A decrease in Skp2 expression and a reciprocal increase in p27 expression were found in dose- and time-dependent manner in H. pylori infected AGS cells treated with rosiglitazone. Conclusions: Rosiglitazone inhibited the growth of H. pylori infected AGS cells. Rosiglitazone attenuated Skp2 expression, thereby promoting p27 accumulation in H. pylori infected human gastric epithelial cells. Further studies will be needed to find the effects of accumulation on cell turnover in H. pylori infection and the role in the H. pylori-associated gastric carcinogenesis.</P>

南北韓 國史敎科書에 登場하는 國王, 王族의 人物 比較

김인식,김선규 한국교육과정학회 2000 교육과정연구 Vol.18 No.2

본 연구는 남북한의 중등학교 국사 교과서에 등장하는 인물 중 국왕·왕족에 대하여 양적인 측면에서는 각 교과서별·시대별 분포와 설명이 있는 인물의 수 및 비율을, 질적인 측면에서는 공통으로 등장하는 인물에 관한 서술을 비교하는 것이었는데, 비교 대상 교과서는 남한의 중학교 및 고등학교 <국사>교과서와 북한의 고등중학교 국사교과서인 <조선력사>였다. 먼저 남북한 국사 교과서에 등장하는 전체 등장 인물의 수 및 비율을 각 교과서별·시대별·유형별로 분류하였다. 이어 남북한 국사교과서에 등장하는 국왕·왕족의 수 및 비율을 각 교과서별·시대별로 양적으로 분석하고, 각 인물의 양적인 비교를 보완하기 위하여 단순 등장 인물과 설명이 있는 인물의 등장 횟수 및 비율도 산출하였다. 아울러 이들 국왕·왕족이 남북한 국사교과서에 공통 및 어느 한쪽에만 등장하는 인물로 분류하여 각 시대별로 나누어 제시하였다. 다음으로 남북한 공통 등장 인물에 대한 질적인 비교는 인물의 '활동 분야·역할'의 측면, 서술 방식·비중'의 측면, 그리고 '인물 평가'의 측면으로 나누어 고찰하되 주로 각 측면별로 남북한이 상이하거나 부분적으로 일치하는 인물의 서술을 중심으로 논의 하였다. 비교의 결과 남북한 국사 교과서의 등장 인물을 양적으로 분석하면 인물의 수는 남한의 <국사>가, 설명이 있는 등장 인물은 북한의 <조선력사>가 더 많았으며, 남북한 공통 등장 인물보다 어느 한쪽에만 등장하는 인물의 수가 더 많았다. 이들 국왕·왕족을 질적으로 비교하면 인물의 '활동 분야·역할'과 같은 사실적 진술보다는, 인물의 '서술 방식·비중' 및 '인물 평가'의 측면에서 상이하거나 부분적으로 일치하는 노력이 요청된다. 하지만 남북한의 국사 교과서에는 이질적인 측면뿐만 아니라 유사하거나 동질적인 부분도 많은 만큼 공통적인 점은 더욱 심화·확대시키고, 차이점에 대해서는 이질성 극복을 위한 보다 적극적인 대처가 필요하다고 본다. The purpose of this study was to analyze the historical characters appearing in national history textbooks of South and North Korea, and to compare their similarities and differences in terms of quantitative dimension and qualitative dimension, In order to achieve these goals, this study overviewed the existing curricular structure and history education of South and north Korea, and analyzed the following three history textbooks ; <Junghak Kooksa> which is the history textbook for middle schools of South Korea, <Kogyo Kooksa> , which is the history textbook for high schools of South Korea, <Josun Ryuksa> which is the history textbook for secondary education of North Korea. As the quantitative approach, this study counted the frequency of all characters appearing in the textbooks, and divided them into a group of commonly appearing characters and a group of characters appearing in one part among three textbooks. Then, the frequency and the rate of all characters' appearance were calculated separatedly and compared with each other. As a result, some quantitative differences were founded in total counts of appearing characters in three textbooks. In total frequency of characters appearing in textbook, the history textbook of South Korea (<Junghak Kooksa> : 393, <Kogyo Koodsa> : 512) contained much more characters than North Korea's (<Josun ryuksa> : 348). And, commonly appearing characters in three comparative textbooks were 133, which amounted to only 18% of total numbers of appearing characters(735). It means that there are lots of differences between south Korea and north Korea in the number of appearing characters. And, as the qualitative approach, this study tried to analyze and discuss the similarities and difference of commonly appearing characters in three textbooks in terms of a character's activity area and role, description and weight of him/her, and historical evaluation of him/her as a whole. As a result, much more similarity was found in character's activity area and role any other aspects. On the other hand, in the aspect of description and weight of a character, difference between three textbooks was much more than similarity, and partially accordant characters were the most in historical evaluation of characters. Nowadays waking to the unification of South and North is faster and faster. So when we compare and study south and north Korean history education and characters in textbooks, we need to study more about 'how same' than 'how different'. Since appearing characters in textbook were deeply connected with their historical background and situation, how to describe a character would greatly influence on the historical interpretation. Therefore, in order to identify the reality of a character, we need a careful analysis on the historical viewpoint of textbook writers. It exceeds. however, the task and the focus of this study. In other word, based on the results of this study, a much more in-depth analysis on types of characters, modes of explaining them, and socio-cultural context should be continued in the future.

The Effect of Parental Imprinting on the INS - IGF2 Locus of Korean Type I Diabetic Patients

(Heung Sik Kim),(Dong Wook Lee),(Sang Jun Lee),(Bo Hwa Choi),(Sung Ik Chang),(Hyun Dae Yoon),(In Kyu Lee) 대한내과학회 2001 The Korean Journal of Internal Medicine Vol.16 No.4

N/A Background: Insulin-dependent diabetes mellitus (IDDM) is caused by the autoimmune destruction of pancreatic β-cells. Susceptibility to IDDM appears to depend on more than one genetic locus. Evidence of a genetic linkage for IDDM2 was found in male meioses from French and North American populations. It is linked to maternal imprinting (i.e. monoalleleic expression of the insulin gene) that is considered the most likely cause of these gender-related differences. IGF2 is expressed only in the paternal allele and therefore, is considered a candidate gene for IDDM2 transmission because of its important autocrine/paracrine effects on the thymus, lymphocytes and pancreas. Nevertheless, it remains controversial whether the parental origin of IDDM2 influences IDDM susceptibility. Methods: Using PCR and semi-quantitative RT-PCR, we analyzed the INS/PstI+1127 and IGF2/ApaIpolymorphisms and RNA expression level between PstI (+/-) and PstI (+/+) to determine genotype and allele-specific expression of the INS and IGF2 genes. Results : INS/PstI(+/+) and IGF2/ApaI(+/-) were observed in 36 (97.3%) of 37 IDDM patients and in 29 (72.5%) of 40 IDDM patients, respectively. The presence of both IGF2 alleles in RNA was observed in 21 (91.6%) of 24 IDDM patients. Our results show a 3-fold increase in RNA expression from PstI (+/-) allele over PstI (+/+) allele. Conclusion: Our conclusion does not entirely exclude IGF2 as the gene involved in IDDM2, even though the parental effect of IDDM2 transmission is not related to IGF2 maternal imprinting. The INS genotype appeared mostly in the PstI (+/+) homozygote and, therefore, we could not explain the INS imprinting pattern in Korean type 1 diabetic patients. Genetic differences between populations may account for the discrepancy between Korean type I diabetic patients and American or French type I diabetic patients.

1930년대 안재홍의 `조선학`론

김인식(Kim, In-Sik) 한국인물사연구회 2015 한국인물사연구 Vol.23 No.-

The term ‘Joseonhak" (Korean Studies, Koreanology) was first proposed by Choi Nam-seon in 1922 and 1927 in an effort to establish it as a field of study. The movement toward ‘Joseonhak" arose again as scholars commemorated the 99th anniversary of the death of Jeong Yak-yong (Dasan). Jeong In-bo, Mun Il-pyeong, and An Jae-hong, while raising public"s interests in Dasan, advocated ‘Joseonhak" with equal enthusiasm. Jeong In-bo, who is usually regarded as the leader of ‘Joseonhak", did not attempt to define it. Mun Il-pyeong, who defined and exhorted it in his own way, did not link it to Silhak (Practical Studies) of the late 19th century Joseon dynasy of Korea. It was An Jae-hong who connected ‘Joseonhak" with the public"s strong interest in Jeong Yak-yong around 1934. This paper aims to investigate An Jae-hong"s theory of the ‘Joseonhak" (Korean Studies). An Jae-hong used the term ‘Joseonhak" even before 1934, but it was in the last quarter of 1934 when he defined his concept of it. Prior to 1934, the term ‘Joseonhak" had not been a weighty concept in An Jae-hong"s theory of national movement, but he began to embrace it enthusiastically beginning in 1934. Around 1934, An Jae-hong judged that it was impossible to continue the political struggle against Japanese occupation by forming political organizations such as Singanhoe. As the fascist colonial rule strengthened, he advocated for a Movement for Korean Culture for the purposes of studying the past and present of the Korean people as a means of national survival, and uplifting the modern national consciousness among people. As he reified the Movement for Korean Culture, he contended that proclaiming ‘Joseonhak" was a way to succeed in devoting oneself to Korean culture. In this regard, ‘Joseonhak" was one area of practice in the Movement for Korean Culture.

췌담관 합류이상이 있는 환자에서 담도계 손상 기전에 대한 연구

정인호,정용식,김지훈,최수윤,김정운,김욱환,홍정,왕희정,유병무,김진홍,한재호,김영배,김재근,김명욱 한국간담췌외과학회 2003 한국간담췌외과학회지 Vol.7 No.2

편두통 환자의 임상 양상 및 생체전기 자율반응과의 상관성 고찰

이현종,정인태,김수영,이두익,김건식,이재동,이윤호,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objective : We had a clinical report in headache but didn't in migraine. We have planned this study in order to get the basic data of migraine in oriental medicine. Methods : The patient of 36 in migraine checked sec, age, onset, family history, severity of pain, influences of life, induced cause, clinical pain characteristics, associated symptom, treatment style, and paescription, frequency, using period of analgesics by a questionnaire and differentiated syndromes in migraine and evaluated autonomic bioelectric response recorder(ABR-2000). Results : There are 23.4% in prevalence rate of migraine. The ratio of sex is M: F=1:17. The age of an attack is the highest in thirties. The patient are the most in forties. The mean duration of illness is 12.0±9.9 years. 83.4% had a family history. 61.1% had a moderate grade in severity of pain. 77.8% selected fatigue in induced cause of migraine. 69.4% had tingling sense, nausea and vomiting in the associated symptoms. 91.7% used analgesics for treatment and 51.5% of them used analgesics voluntarily. 61.9% of them take analgesics less than once in a week. 33.6% had the phlegm syncope headache in differentiation of syndrome. In ABR-2000 results, item of graph showed low tendency mostly. Conclusions : We expected that this re port of clinical progress, differentiation of syndromes and ABR-2000 results in migraine would be used basic data by oriental medicine to treat migraine.

國家意識의 實態와 그 對策 : 국기, 애국가 및 국민교육헌장의 보급을 중심으로

李建衡,盧禎埴,成炳卓,姜萬石,朴泰岩,朴仁熙,金漢植 대구교육대학교 1971 論文集 Vol.7 No.-

國旗의 常備現況은 總體的으로 보아 低調한 實態에 있다. 全體 標集者의 86.8%가 國旗를 備置하고 있다는 反應을 보였으나, 이 數置가 보이는 內容은 區區하다. 卽 깃발과 그 附帶品一切를 完備한 家庭은 全體의 42.5%에 不過하고 깃발만을 備置한 家庭이 20.4%, 函까지를 갖춘 家庭이 45.8%로서 約 半數의 家庭이 適當한 場所에 깃발을 保管하고 揭揚時에는 적의한 막대기로 代用할뿐만 아니라 깃발조차 없는 家庭이 約 15%에 이르는 셈이다. 最少限 깃발만이라도 갖춘 家庭을 地域別로 보았을 때 中都市의 96%, 農村의 90%만이 全體의 86.6%를 上廻하고 있고 漁村 79.6%가 特히 低調함은 注目할 일이다. 그리고 附帶品의 具備狀況이나保管도 中都市가 比較的 充實하고 漁村이 低調한 傾向을 보이고 있으며 意外로 農村보다도 大都市가 모든 面에서 不實함도 注目할 일이다. 國旗의 保管이나 揭揚은 主로 젊은 學生層에서 擔當하고 있다. 이러한 傾向은 農·山村일수록 年令이 낮아지고 中都市와 大都市는 비슷하게 年令이 높아지는데 이로 미루어 高令層의 啓蒙이 要請된다고 하겠다. 國慶日의 國旗揭揚狀況는 質問紙에 依한 應答 結果는 約 70%이나 實際 揭揚은 約 35%의 低調한 것이어서 깃발조차 갖고 있지않는 約 15%를 감안하더라도 言行이 一致하지 않는 一面을 엿볼 수 있다. 特히 中都市(37%) 大都市(49.2%) 農村(37.8%)과 對比할 때 前述한 깃발 備置狀況과 逆現象을 보인 都市人의 覺醒을 促求하지 않을 수 없다. 國旗揭揚法의 正確性 與否는 問題가 될 것이나, 大部分 알고 있으면서도 關心과 誠意가 없어서 國慶日에 國旗를 揭揚하지 않는다고 反應한 데 對한 積極的인 對策이 要望되며 特히 國慶日을 모르기 때문에 憩揚하지 않는다은 것을 1順位로 反應한 山村을 留意해야 겠다. 國旗의 뜻을 잘 모른는 國民이 大部分이고 이러한 現象은 意外로 靑年層일수록 더한 것이 豫想과는 相反되고 있다. 國旗의 制定由來나 그 國家象徵性을 認識하지 못하는 傾向 亦是 같은 現象을 보이고 있다. 다만 由來나 象徵性에 對한 認識에 關한 限 都市民과 漁村民이 比較的 높고, 農村과 山村民이 相對的으로 낮다. 農·山村에 比한 漁村, 大都市에 比한 中都市의 住民이 갖는 相對的으로 높은 認識度는 東海岸民의 安保意識과 中都市人의 等質性 및 國家施策의 浸透 容易性에 緣由하는 것이라고 생각된다. 그리고 우리 國民은 國旗의 뜻을 모른는 者가 3分의 1에 該當하고 國旗에 대한 公式的 敎育을 받지 못한 사람도 3分의 1에 이르며 國旗를 그릴 수 없는 사람이 半以上이나 된다. 國旗에 關한 諸般 認識度는 男子보다 女子가, 年令別로는 老令層이, 生活程度는 낮을수록 低調한 것을 알 수 있고, 全體 國民의 우리 國旗에 對한 滿足度에는 유감이 없음을 보여주고 있다. 愛國歌의 普及 實態는 過히 不振한 便은 아닌 것 같다. 80.9%의 國民이 적어도 愛國歌의 1절以上을 부를 수 있고 愛國歌가 들려올 때 約 18.6%의 國民을 除外한 大多數 國民이 차려姿勢 또는 경건한 態度를 가질뿐만 아니라 愛國歌의 普及强化를 所望하는 反應이 78.1%나 되었다는 것이 이를 立證하고 있다. 그리고 地域的으로는 大都市에 比해 中都市가 農·山村에 比해 漁村이 보다 健全함을 보여주고 있다. 그러나 部分的으로는 問題가 없는 것도 아니다. 愛國歌를 1절도 못외우는 18.4%, 愛國歌가 들려와도 無關心한 18.6%의 國民이 있고, 이러한 反應度는 愛國歌 부르기 敎育을 받은 적이 없는 33.2%의 國民, 愛國歌 解說敎育을 받은 적이 없는 47.8%의 國民 및 한해에 한번도 愛國歌를 부를 機會가 없는 36.0%의 國民이 있다는 事實과 有關하리라고 생각된다. 上述한 問題點은 地域的으로는 都市보다는 農·山·漁村이, 特히 農村에 比해 農·山村이, 學歷 및 年令上으로는 文盲者 및 國·漢文 解讀者를 그 속에 간직하고 있는老令層에, 男子보다는 女子가, 또한 生活程度는 낮을수록 尤甚하다는 것을 指摘할 수가 있다. 全體的으로 보아서는 中都市의 實積이 大都市 및 餘他地域보다 良好하고 豫想한대로 農·山村에 比해 漁村이 두드러진 特徵을 보이고 있는 點이다. 그리고 愛國歌의 普及 및 그 敎育에 있어서는 資料 通計上으로는 그 어떤 經路보다도 學校敎育의 充實이 가장 效果的이었다는 것을 보여주고 있으나 愛國歌의 普及强化策에 對한 反應을 中心으로 본다면 山·漁村을 除外한 모든 地域이 新聞 放送 等의 報道機關을 通한 普及을 希望하고 있다. 이는 이미 指摘한 老年層, 文盲者, 國漢文 解讀者, 및 家庭主婦인 女子를 相對로 한 境遇에 異論이 있을 수 없겠고, 報道機關의 普及率이 낮은 山村이 學生啓蒙運動을 그리고 安保意識이 强한 漁民이 地域別 成人敎育을 希望한다고 보아 無妨할 것이다. 그리고 劇場 演藝物을 通한 普及은 效果가 적을 것임이 나타났고 그 밖에는 妙案이 없는 것으로 反應되었다. 그리고 愛國歌의 普及强化를 所望하는 意志는 强하다고 할 수 있는 것은 이미 指摘하였거니와 이 境遇에는 規制的인 方法보다도 自律的인 方法 例컨대 報道機關을 通한 宣傳啓蒙이나 山·漁村을 對象으로 한 學生啓蒙運動 또는 里動單位의 自體啓蒙을 希望하고 있음을 特記해 둔다. 國民敎育憲章 普及實態의 全體的인 傾向은 公布事實마저도 모른다 24.0%, 憲章冊子를 가지지 않았다 約 30%, 制定의 理由를 모른다 30% 等으로 보아 制定公布된지 3年이란 時間的 經過에 비추어 豫想外로 低調하다 할 수 있으며 地域別로 보면 制定事實의 知悉, 內容理解 分析努力, 暗記努力, 普及施策 贊成面에서 中都市가 大都市보다 理解度가 높게 나타났으며 漁村이 現實與件上 國家意識이 높으리라는 豫想은 立證되지 않았으며, 山村은 豫想한대로 普及狀態가 極히 不振하였다. 性別로는 男子의 理解度가 높고, 年令別로는 年令이 낮을수록 學歷은 높을수록 生活程度는 높을수록 普及實態나 理解度가 높아지고 있다. 다만 制定理由의 知悉面이나 分析經驗 普及施策에 對한 贊同面에서 大學卒業 以上의 學歷者가 高等學校 卒業者보다 낮게 나타난 點은 異彩로운 現象이다. 職業別에 있어서는 大體로 公務員, 商·써비스業, 無職, 農業의 順으로 意識이 높다. 憲章公布事實을 알게 된 經路나 普及을 爲한 效果的인 施策의 選擇狀況을 보면 報道機關이 가장 效果的이며 學校敎育의 影響이 意外로 低調함을 發見할 수 있다. 普及施策中 學生을 通한 啓蒙運動에 對한 共鳴度도 낮고, 劇場 및 演藝機關을 通한 普及은 큰 支持를 받지 못하고 있음이 發見되었다. 暗記動機는 自發的인 境遇가 29.2%에 不過화고, 憲章에 對한 一般의 關心度가 낮으며 普及運動의 反對理由로는 "形式에 흘러 實效性이 없다"가 24.2%로 가장 높다. 以上을 綜合해 볼 때 國旗, 愛國歌, 및 國民敎育憲章 할 것 없이 그 普及 및 認識度가 豫想外로 低調함을 알 수 있다. 愛國歌에 關한 限 80.9%의 國民이 1절 以上의 愛國歌를 부를 수 있는 바 他 2者에 比해 相對的으로 良好한 便이나 公式集會의 慣例 탓으로 4절까지를 모두 외우는 者는 極히 不振하다. 要컨대 三者가 모두 敎育 또는 啓蒙이 不實하였음이 立證되었으며 特히 知識水準이 낮은 老年層과 性別로는 女子, 地域的으로는 山村, 農村, 漁村의 順으로 不振하였고 豫想外로 大都市 및 大學卒業者가 低調하였음도 發見되었다. 그리고 愛國歌에 關한 限 學校敎育으 效果가 斷然 越等한 反面 國民敎育憲章의 普及 및 認識은 學校敎育보다도 報道機關의 啓蒙이 奏效하였음이 發見되었다. 그리고 國旗의 國家象徵性에 關한 認識은 光復後의 學校敎育을 받은 靑少年層이 보다 健全하여 日帝下에서 靑壯年期를 보낸 壯·老年層이 意外로 低調한 傾向을 보여주고 있다. The research in this report was done to discover the reality of the korean National Consciousness. By this we mean an awareness of the National flag, the National Anthem, and the Charter of National Education in Korea. Also since threre appears to be a lack of awareness in certain areas we have attempted to propose adequate measures to imporve these conditions. Methods and materials used for this study are as follows: the method was of Random Sampling in which we selected randomly 900 men and women living in a city, a town, farm areas, remote areas, and sea-side areas. The materials was an interview form called "the schedule" which consisted of 46 items. From the data received we reached the conclusion that knowledge about the National Flag, the National Anthem, and the Charter of National Education in Korea was generally poor. This trend appeared more in the farm area, remote area, and seaside area then in the city and town; more in women than in men; more in the old than in the young, more in those of lower academic careers and lower economic levels than of their counterparts with better careers and living levels. From the above conclusions we propose that the community schools and the mass communication system in korea strive actively to increase the instruction of these people in order to improve the national consciousness of the above mentioned people.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.