김환기의 근대기 작품에 나타난 체험과 감각

김인아(Kim In-ah) 한국근현대미술사학회 2015 한국근현대미술사학 Vol.29 No.-

It is prevalent opinion that Kim Whan?ki from the 1930s to the early 1940s was an abstract artist. As well known, Kim had strong ties with the avant-garde communities of Japan when he was a student there as well as when back to Korea while producing abstract works. Kim later formed a neorealism community with Yoo Youngkuk and Lee KyuSang, where he seeked the ‘Neo-Reality’. He also reflected his interest in korean tradition and antiques in his work while having made an exchange with artists, poets, and writers who had worked through ‘Munjang’ that is literature magazine. That much of the academic literature on Kim’s paintings from this period have been focused on abstract and avant-garde art and orientalism may be a natural consequence of his historical trajectory as the above. As the advanced researches tell, Kim Whan?ki’s interest is not the departure from an object but the way ‘abstractifying’ an object, while pursuing the abstract art. This study also begins from the premise that the key element necessary for interpreting Kim’s abstract art is the way rather than the concept. I would like to go even a step further to argue that the form and content of the abstract in Kim’s work reflect the artist’s personal experiences and emotional sensations. And I’ll argue that such personal experiences-which exist on the outskirts of Kim’s abstract art-are imbued with a kind of romanticism. To illuminate these points, I analyze the abstract features of Kim’s work that appear as geometrical designs in conjunction with the social atmosphere of the era, and also interpret the artist’s personal experiences reflected in the work through references to articles, photographs, and related written works published in the literary magazines of the day. I attempt to show that Kim Whan-ki’s painting which abstractly portrayed the city and machines-symbols of the most cutting-edge elements of civilization- are not simply a matter of style but concrete expressions of the artist’s existential interpretations of nature, life, and modern civilization. It may seem unusual for an artist who interprets the world through the lens of existentialism to pursue such an abstract style. However, at that time, this is not unusual. This is because the avant-garde discourse in those days was developed in each artist’s personal understanding. The experiences of the 1930s that appear in Kim’s work were personal and everyday experiences of modern civilization, and this is why his artwork includes hints at the modernist emotional connection with urban life. Kim’s nostalgia for the modern lifestyle he experienced during his student years in Tokyo occasionally appears as a landscape that is in turn representational or contemplative. These approach is similar to imagism in literature. Kim Gi-rim, a leading Korean modernist poet, defines poetry as the expression of not the mental but the “real” world in writing. Similarly, Kim Whan?ki’s work is an expression of reality as created through the artist’s memories and experiences.

영화국가 만들기

김선아(Kim Sun Ah) 한국영화학회 2011 영화연구 Vol.0 No.48

A foundation of North Korean cinema was established during the 1960s to 1970s and Film Art by Kim Jong-il is placed in its core. Re-mediating Kim Il-sung Suryung(the great leader)’s struggle and revolutionary operas written by Kim Il-sung into cinema as a modern technology, Kim Jong-il reformed North Korea as Cinema-state. In doing so, the heredity of the dictatorial power was naturalized and necessitated just as a transmission to new modern media. Cinema operated as signs of everyday life which North Korean people could interpret their reality through, and provided an opportunity that people took part in and shared Kim Il-sung Suyung’s myth. As accelerating the centralization and unification of economy, politics and culture under the name of Suryung, North Korean cinema has been distorted with a drastic development. Kim Jong-il deleted the existing film history with emphasizing the tradition of revolutionary cinema and wrote Film Art that became the origin of other art theories. Since then Kim created films of the Suryung figure and established the Juche Idea(self-reliance/subjecthood). The procedure of development of North Korea film history from a revolutionary cinema during 1960 to 1970 and Film Art to a cinema of a Suryung figure let us know a birth and fall of Kim’s Cinema-State and a perfect union of technology and state power. Film Art provided the foundation for the aestheticization of politics and melodramaticization of a history in the Cinema-state. Film Art was the only art theory written by Kim Jong-il in the 1970s where Kim reckoned cinema as the representative art of socialist realism for the age of independent and creative Juche. It emphasizes a human being’s consciousness-raising, the organization of feelings and contents. At the same time it inherited the problems of romanticism, organicism and passive human being. The illusion of Father-Nation-State on a huge cinematic screen in North Korea during the 1960s to 1970s were vanished. Cinema-State faced to the end because of intolerable distance between a reality and a cinema and the development of multimedia technology.

초등학교 고학년 아동의 성별 음란물 접촉실태와 성 갈등에 대한 연구

차남현 ( Nam Hyun Cha ),왕명자 ( Wang Myoung Ja ),유경희 ( Kyung Hui Yu ),김정아 ( Jeong Ah Kim ) 경희대학교 동서의학연구소 2007 동서간호학연구지 Vol.13 No.2

본 연구 대상 아동 952명중 ‘음란물에 대해 들어본 경험이 있다`` 고 응답한 남아는 63. 2%,(288명) 이고 여아는 60.5% (300명)이지만,‘음란물에 접촉한 경험’이 있다 ``에는 남아 34.4% (l57명), 여아27.4% (l36명)가 응답하여, 대부분의 아동은 음란물에 대하여 들어본 경험은 있지만, 접촉한 경험은 없는 것을 알 수 있다. 초등 아동을 연구한 Kim과 woo (2001), Kim (2002)과 Kang (2004)이 음란물 접촉자율을 각각 20.3%, 28.6%, 30%로 보고한 선행연구 결과보다 더 높은 퍼센트를 나타내었다. 처음 음란물을 접촉한 시기는 ``5학년 때’가 남가 아동 39.5%, 여아 44.1%로 가장 많았고, ``4학년 이전’도 남아 31.8% , 여아 30.9% 로서, 음란물을 첫 접촉한 시기가 4학년 이전 16.8%(Kim,2002) , 19.8% (Oh, 2003)라는 선행연구에 비하면, 본 연구 대상 아동의 ``4학년 이전’ 음란물 접촉 비율이 또한 높은 것을 알 수 있다. 이와 같은 결과는 매스미디어를 통해 초등학교 아동들이 상업적인 성에 노출과 관련이 있는 것으로 보이며 매스미디어의 광범위성, 대중성, 능동성, 동시성의 특성을 고려한다면 앞으로 음란물 접촉을 및 저학년 접촉빈도는 계속 증가할 것으로 생각된다. 접촉한 음란물 유형에 대한 복수응답 결과,‘컴퓨터를 통해 음란물을 보았다``는 남아 82.8%(l30명), 여아 90.4% (l23명)로 가장 빈도가 높은 접촉유형이고’ 다른 음란 접촉 유형은 비슷한 빈도 분포를 나타내었다. 컴퓨터를 통한 음란물에 초등학교 아동이 쉽게 접촉하고 있음을 지적한 선행연구 (Yom, Yun, & Lee, 2002; Hong, 2003; Kang, 2004)의 결과와 일치하고 있다. 이와 같은 결과는 개인용 컴퓨터와 인터넷 사용인구가 급증하고, 학교나 주택가 주변 PC방이 즐비 하면서 음란물들을 더욱 쉽게 볼 수 있게 된 때문으로 사료된다. 이에 대해, Kim과 woo (2001), Park(2001)는 연구에서 컴퓨터 음란물 차단프로그램의 설치가 각각 19.4%, 13.3%에 불과하다고 지적하고 있다. 사실 컴퓨터 매체를 이용한 인터넷 음란물은 대중성과 동시성 등의 특성이 있어 미성년자의 접근이 쉽고 광범위하게 노출이 될 수 있는 반면, 통제할 수 있는 시스템과 대책이 매우 부족한 실정에 있다. 따라서 인터넷 음란물에 대해 정부에서는 청소년보호법 이 실효성을 거둘 수 있도록 규제 및 처벌을 더욱 엄격하게 하고, 음란물 차단 프로그램의 설치를 강화해야 할 필요성이 있다. 음란물에 접촉하는 동기는``우연히`` 라고 응답한 경우가 가장 많았고 (남아 51.6%, 여아 53.7%) ‘스팸메일’을 통해서, 친구 및 형제’의 권유로,‘호기심``으로 직접 찾아봄순으되 남녀 등 모두 우연히 접하는 경우가 많았다.‘스팸메일’을 통해사는 남아보다 여아가 접하는 경우가 더 많은 것으로 나타났다. 이는 통계 청 (2005)에서 제시한 청소년 음란물 사이트 접속경로로 우연히 (남이 32.7%, 여아 35.5%), 친구나 선후배 소개로 (남아 31.5%, 여아 11.7%), 일부러 음란물 검색 (남아 20.9%, 여아 6.9%), 스팸메일 (남아 6.5%, 여아 14.8%)과 순서가 일부 일치함을 보이고 있다. 이와 같이 아동이 무엇보다 우연히 음란물을 접하는 경우가 많은 결과는 포르노 사이트의 무차별적 음란물 배포에 대하여, 초등학교 아동들이 무방비 상태로 노출 되어 있으며, 현재 이를 차단할 수 있는 프로그램의 설치의 미흡을 의미하는 것이다. 음란물과 접촉하는 빈도는 ‘거의 안보거나 특정 싸이클이 없다. (남아 73.7%, 여아 87. 2%)는 응답이 많았고)거의 매일 보는, 남아는 4.5%, 여아는 0.7%였다. 이는 통계청 (2005) 의 청소년음란사이트 이용경험 조사에서 ‘한번도 없음’(남아 24. 5%, 여아 70.6%), ‘일년에 l-2회, 접촉히는 남아가 l5.8%, 여아 8.5%,‘한달에 l- 2회’ 접촉하는 남아 26.8%, 여아 4.8%, ‘일주일에 l- 2회’ 접촉하는 남아 l5,9%, 여아 1.9% 라는 결과에서 제시하듯이, 대부분 이동은 음란물에 접촉하지 않고 있으나, 음란물 접촉은 남아가 여아보다 더 많았다. 음란물과 접촉하는 기간은·15분 미만이 남아 86.8%, 여아 96.2%로 가장 많았고, 15분 이상’은 남아 l3.2%, 여아 3.8%로 대부분의 아동은 음란물 접촉시간이 짧은 것을 알 수 있다. 그러나, 소수이기는 하나 정기적으로 음란물에 접촉하는 아동에 대한 주의를 기울일 필요가 있다. 음란물을 정기적으로 이용하는 아동일수록 학습에 많은 지장을 받고 있음은 물론, 성과 관련된 반응에 있어서 보다 쉽게 자극 받고 충동을 일으키며, 그 충동을 실제 행동으로 옮길 가능성이 크고 (oh, 2003), 중독성이 강하며, 성에 대해 비하하는 태도와 행위, 충동조절 능력 저하, 폭력적이 거나 모욕적인 성행위를 선호하게 될 수 있다. 따라서, 정부와 학교당국, 부모님의 음란물에의 적극적이 고 효과적 인 대처 방안이 시급하다. 음란물과 접촉하는 장소는 자기 집이 (남아 68,8%, 여아 81.5%) 가장 않았고 친구집(남아 16.0%, 여아 7.6%), PC방 (남아 4,2%, 여아 5.9%), 학교 순으로 응답하였다. 이는 통계청 (2005)에서 보고한 6-l4세 어린이가 이용하는 인터넷 장소로 가정 90.5%, PC방 빛 게임방 25. 8%, 학교 18.2%라는 결과와 순위가 일치 하고 있다. 따라서 음란물 접촉이 가장 많다고 응답 한 가정에서 부모의 음란물을 방지 대책마련이 요구된다. 공개적으로 아이들과 PC를 공유하는 방을 마련하고 음란물 차단 시스템을 PC에 설치하며, 수시로 관심 있게 보는 사이트 및 정보를 확인,대화하고 컴퓨터 이용시간을 제한하여 아이들의 건전한 컴퓨티 이용문화를 형성하도록 지도하여야 한다. 음란물 접촉 이유는 ‘우연히’가 가장 많았고 (남아 35.7%, 여아 57.3%), 남아는 ‘호기심’때문에,‘스팸메일,을 열어보다가,‘친구``가 권해서,‘재미, 스트레스 해소와 성충동’ 때문이라고 답했고, 여아는 ‘스팸메일’ 윤 열어보다가,‘호기심’ 때문에,‘친구’가 권해서,‘재미,스트레스 해소’ 위해,‘성충동과 성적지식’을 얻기 위해 순으로 응답하였다. 이는 의도적인 접촉보다 비의도적인 접촉이 많다는 것으로 해석되어져 다행스럽긴 하나, 음란물은 처음 접했을 경우 충격적이지만, 호기심을 가지고 접하면서 무뎌지고 점차 더 자극적인 음란물을 경험하고자 하며 모방행동으로까지 발전되는 특성이 있다고 한다. 초·중 아동을 대 상으로 한 Hong(2003)의 연구에서 음란물 경험 후 실제로 ‘모방행동을 해 본적이 있다’ 에 11.l%가 응답한 것으로 볼 때 절대 간과해서논 안 될 문제이다. 음란물 접촉 후 반응은 부정적 반응에 대한 응답율이 높은 반면, 긍정적이거나 충동적 반응에 대한 응답율은 저조하였다. 부정적인 반응은 ‘부끄럽고 창피하다’가 (남아31.51%, 여아 32.05%)가장 많았고, 남아는 ‘죄책감’, ‘내가 이상한건가 하는 생각’, ‘혐오감’을, 여아는 ‘혐오감’, ‘내가 이상한건가 하는 생각’, ‘죄책감’ 순으로 반응하였다. 음란물 접촉 후 반응이 긍정적 반응보다는 부정적 반응에 대한 응답이 많은 것을 볼 때, 음란물 접촉아동은 음란물을 통해 성이 아름답고 신성한 것이 아닌 은밀하고 부끄러운 것으로 인식되 왜곡된 성의식을 가지게 되며, 혼란과 갈등을 겪게 될 것으로 보인다. 이런 결과는 선행연구(Kang, 2004; Kim, 2004; oh, 2003; Kim, 2002)에서도 지적하고 있다. 성 갈등은 남녀 아동 모두 음란물에 접촉한 아동이 접촉하지 않은 아동보다 더 느끼는 것으로 나타났으나,음란물 접촉후 아동간의 성 갈등 차이는 통계적으로 유의하지 않아 성별에 따른 성 갈등은 차이가 없었다. 음란물에 노출될수록 중독성이 강하여 성 정체성이 확립되어야 하는 초등학교 고학년 아동들에게 성에 대한 부정적인 영향을 미치기 쉬우므로 음란물로부터 보호하기 위한 대책마련이 시급하다. 서구에서는 영상매체가 청소년에게 미치는 영향을 방지하기 위한 스크린 (screening) 컴퓨터 프로그램을 개발하거나 Tv에 V-chiP을 설치해 부모나 성인의 감독 없이 영상매체에 근접하지 못하게 한다 (Cho & Kim, 2004). 우리나라는 아직 그러한 방지책이 실질적으로 이용되고 있지 않기 때문에, 무조건 음란물을 못보게 막으려 시도하기 보다는 아동에게 음란물에 대한 비평능력을 심어주어 스스로 통제할 수 있도록 하는 성교육이 우선적으로 고려되어야 한다고 생각된다. Gruer와 Grube(2000)의하면, 얼마나 위험요인이 될 수 있는지 아무런 비판없이 무분별하게 청소년이 음란물에 접하 면,음란물에 대한 부정적인 영향을 더 많이 받을 수 있었으나, 실제로 성교육을 통해 청소년이 올바른 성 지식 습득하였을 때 성 태도가 긍정적으로 변하였고,음란물의 영향을 더 적게 받고, 직접적인 성행동을 감소시킬 수 있었다. woo, Kim과 Park (2001) 은 중학교 청소년을 대상으로 성교육이 컴퓨터와 비디오 음란물 접촉에 미치는 효과를 파악하기 위한 비동등성 대조군 전후 실험연구를 한 결과,성 교육 후 실험군은 성교육을 받지 않은 대조군보다 음란물 접촉에 대한 의식점수가 높았고’ 컴퓨터를 통한 원조교제에 대한 의식점수가 높았으며, 음란물 접촉빈도가 적었다고 하면서 음란물에 대한 성교육의 중요성을 강조하였다 따라서 가정과 학교에서 부모나 교사인 어른들의 입장에서 고려된 보수적이고 전 근대적인 성교육방법 과 내용만을 고수하여 무조건적으로 음란물 접촉을 막는 것보다는, 아동이 올바른 성의식을 확립하여 스스로 볼 수 있는 것과 보지 않아야 할 것을 구별할 수 있는 비판능력을 함양시킬 수 있는 성교육이 필요하다. 결과적으로 아동들 스스로가 성행동의 주체로서 음란물 공해에서도 자신 있게 맞설 수 있는 성숙한 자아로 성장할 수 있도록 도울 수 있어야 하며, 이와 더불어 무차별적인 대중매체로부터 아동들을 보호하는 시스템의 조기 구축이 요구된다. This study was to examine the possibility of the contact with pornographs of elementary school boys and girls and to confirm responses after that, and to compare the feeling of sexual conflict between the boys and girls. Methods: The subjects were 952 5th and 6th graders of elementary school in four city areas(456 boys, 496 girls). Data collection was via questionnaires Results: Except several pupils(34.4% of boys, 27.4% of girls), most of subjects of the study had no contact with pornographs. The response after the contact with pornographs was feeling of shame the most, which was a negative reaction. The sexual conflict appeared more in pupils who had contact with pornographs than in those who had not boys(t=3.84, p<.000), girls(t3.96, p<.000), which showed a significant difference. However, the conflict between boys and girls was not significant statistically. Conclusion: We would like to suggest that a sound control system must be prepared and a development of programs related to sexual education and promotion of ability fighting against them that can release their impulse of sex.

Amino-Functionalized Mesoporous Silica Particles for Ocular Delivery of Brimonidine

Kim, Se-Na,Ko, Song Ah,Park, Chun Gwon,Lee, Seung Ho,Huh, Beom Kang,Park, Yoh Han,Kim, Young Kook,Ha, Ahnul,Park, Ki Ho,Choy, Young Bin American Chemical Society 2018 MOLECULAR PHARMACEUTICS Vol.15 No.8

<P>To treat glaucoma, conventional eye drops are often prescribed. However, the eye drops have limited effectiveness as a result of low drug bioavailability due to their rapid clearance from the preocular space. To resolve this, we proposed amino-functionalized mesoporous silica (AMS) particles as delivery carriers of the glaucoma drug, brimonidine. Because of the presence of mesopores, brimonidine (BMD) could be encapsulated in the AMS with a loading amount of 41.73 μg/mg (i.e., drug loading capacity of about 4.17%) to give the BMD-AMS, which could release the drug in a sustained manner over 8 h. BMD-AMS was also shown to be mucoadhesive due to the presence of both hydroxyl and amino groups in the surface, allowing for formation of hydrogen bonds and an ionic complex with the mucin, respectively. Therefore, when topically administered to rabbit eyes in vivo, BMD-AMS could reside in the preocular space for up to 12 h because of its adherence to the mucous layer. To assess in vivo efficacy, we examined the variance in intraocular pressure (IOP) and brimonidine concentration in the aqueous humor (AH) after applying BMD-AMS to the eye, which was compared with that induced by Alphagan P, the marketed brimonidine eye drops. For BMD-AMS, the duration in the decrease in IOP and the area under the drug concentration in the AH-time curve (AUC) were 12 h and 2.68 μg·h/mL, respectively, which were about twice as large as those obtained with Alphagan P; this finding indicated enhanced ocular bioavailability of brimonidine with BMD-AMS.</P> [FIG OMISSION]</BR>

EGFR 돌연변이와 ROS1 전위를 동시에 가진 폐선암 환자의 Erlotinib 치료 1예

김민환,박예현,박혜정,지아영,송창호,진무년,김영주,김선욱,이중희,김인수,김혜련,김주항,조병철 Ewha Womans University School of Medicine 2014 EMJ (Ewha medical journal) Vol.37 No.1

The rearrangement of c-ros oncogene 1 (ROS1) has been recently identified as an important molecular target in non small cell lung cancer (NSCLC). ROS1 rearrangement and epidermal growth factor receptor (EGFR) mutation were mutually exclusive each other in previous studies, and the clinical implication of co-existence of the two genetic alterations has not been determined. We report a case of 46-year-old female never-smoker NSCLC patient whose tumor harbored ROS1 rearrangement and EGFR mutation concomitantly. She had undergone curative surgery for stage IIIA NSCLC, and the recurrence in left pleura and brain occurred at 2 years after the surgery. She received several lines of chemotherapy including docetaxel plus carboplatin, erlotinib, pemetrexed, and gemcitabine. Erlotinib therapy showed a favorable treatment response with progression-free survival of 9.5 months and partial response of tumor on radiologic evaluations. This case represents a successful erlotinib treatment in a NSCLC patient with concurrent ROS1 rearrangement and EGFR mutation.

Original Article : Geographic difference of epidemiological features of HCV infection in Korea

( Kyung Ah Kim ),( Sook Hyang Jeong ),( Eun Sun Jang ),( Young Seok Kim3 ),( Youn Jae Lee ),( Eun Uk Jung ),( In Hee Kim ),( Sung Bum Cho ),( Mee Kyung Kee ),( Chun Kang ) 대한간학회 2014 Clinical and Molecular Hepatology(대한간학회지) Vol.20 No.4

Background/Aims: The prevalence of hepatitis C virus (HCV) infection in Korea exhibits significant geographic variation, with it being higher in Busan and Jeonam than in other areas. The reason for this intranational geographic difference was investigated in this study by conducting a comparative analysis of the risk factors related to HCV infection among three geographic areas: the capital (Seoul), Busan, and the province of Jeolla. Methods: In total, 990 patients with chronic HCV infection were prospectively enrolled at 5 university hospitals located in Seoul (n=374), Busan (n=264), and Jeolla (n=352). A standardized questionnaire survey on the risk factors for HCV infection was administered to these three groups of patients, and a comparative analysis of the findings was performed. Results: The analysis revealed significant regional differences in exposure to the risk factors of HCV infection. By comparison with patients in Seoul as a control group in the multivariate analysis, patients in Busan had significantly more experience of invasive medical procedures, acupuncture, cosmetic procedures, and multiple sex partners. In contrast, patients in Jeolla were significantly older, and they had a higher prevalence of hepatocellular carcinoma, a lower prevalence of multiple sex partners, and had experienced fewer invasive procedures. Conclusions: There was a significant geographic difference in the exposure to potential risk factors of HCV infection between patients from the three studied regions. This may explain the regional variation of the prevalence of HCV infection in Korea, and should be taken into account when planning strategies for the prevention and management of HCV infection. (Clin Mol Hepatol 2014;20:361-367)

Paricalcitol attenuates lipopolysaccharide-induced inflammation and apoptosis in proximal tubular cells through the prostaglandin E₂ receptor EP4

( Yu Ah Hong ),( Keum Jin Yang ),( So Young Jung ),( Yoon Kyung Chang ),( Cheol Whee Park ),( Chul Woo Yang ),( Suk Young Kim ),( Hyeon Seok Hwang ) 대한신장학회 2017 Kidney Research and Clinical Practice Vol.36 No.2

Background: Vitamin D is considered to exert a protective effect on various renal diseases but its underlying molecular mechanism remains poorly understood. This study aimed to determine whether paricalcitol attenuates inflammation and apoptosis during lipopolysaccharide (LPS)-induced renal proximal tubular cell injury through the prostaglandin E₂ (PGE₂) receptor EP4. Methods: Human renal tubular epithelial (HK-2) cells were pretreated with paricalcitol (2 ng/mL) for 1 hour and exposed to LPS (1 μg/mL). The effects of paricalcitol pretreatment in relation to an EP4 blockade using AH-23848 or EP4 small interfering RNA (siRNA) were investigated. Results: The expression of cyclooxygenase-2, PGE₂, and EP4 were significantly increased in LPS-exposed HK-2 cells treated with paricalcitol compared with cells exposed to LPS only. Paricalcitol prevented cell death induced by LPS exposure, and the cotreatment of AH-23848 or EP4 siRNA offset these cell-protective effects. The phosphorylation and nuclear translocation of p65 nuclear factor-kappaB (NF-κB) were decreased and the phosphorylation of Akt was increased in LPS-exposed cells with paricalcitol treatment. AH-23848 or EP4 siRNA inhibited the suppressive effects of paricalcitol on p65 NF-κB nuclear translocation and the activation of Akt. The production of proinflammatory cytokines and the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling-positive cells were attenuated by paricalcitol in LPS exposed HK-2 cells. The cotreatment with an EP4 antagonist abolished these anti-inflammatory and antiapoptotic effects. Conclusion: EP4 plays a pivotal role in anti-inflammatory and antiapoptotic effects through Akt and NF-κB signaling after paricalcitol pretreatment in LPS-induced renal proximal tubule cell injury.

침 시술로 발생한 Non-O1, Non-O139 Vibrio cholerae에 의한 패혈증

임태섭,지아영,이중희,장수연,김인수,김영주,김범경,김승업,박준용,안상훈,한광협,김도영 Ewha Womans University School of Medicine 2013 EMJ (Ewha medical journal) Vol.36 No.S

Vibrio cholerae is mainly known to cause gastrointestinal infection after seawater exposure or raw seafood intake. It is rarely reported to cause cellulitis or sepsis, but threre has been no known case after acupuncture. Herein, We report a 56-year-old cirrhotic patient of non-O1, non-O139 Vibrio cholerae septicemia caused by cellulitis of both lower extremities after acupuncture.

In vivo study for the hemostatic efficacy and foreign body reaction of a new powder-type polysaccharide hemostatic agent

Yoonhyeong Byun,Eun Jin Kim,Areum Lee,Young-Ah Suh,Hee Ju Sohn,Jung Min Lee,Jae Seung Kang,Yoo Jin Choi,Youngmin Han,Hongbeom Kim,Wooil Kwon,Jin-Young Jang 대한외과학회 2022 Annals of Surgical Treatment and Research(ASRT) Vol.102 No.2

Purpose: Various hemostatic agents have been introduced in therapy as postoperative bleeding is a poor prognostic factor for postoperative outcomes. These products can be divided into those that directly promote the hemostatic cascade and those that physically form a barrier by absorbing blood. The latter, powder-type hemostatic agents have the advantages of being inexpensive and more absorbable with less foreign body reactions (FBRs) and are applicable to a relatively wide area. This study was conducted to verify the safety and efficacy of a newly invented polysaccharide product (OOZFIX, Theracion Biomedical), which improves blood absorption and hemostatic effects. Methods: Two separate animal experiments were performed. The first evaluated FBRs histologically at 3 days, 2 weeks, and 4 weeks, after implantation of OOZFIX in rats, and the second compared hemostatic performance of OOZFIX and Arista AH (Bard) in the porcine liver punch biopsy model. Results: We found minimal FBRs in the 3-day group and no reactions in both the 2-week and 4-week groups after implantation of hemostatic agents. The time to hemostasis of OOZFIX was not significantly different from that of Arista AH (median [interquartile range]: 9 [6–10] minutes vs. 8 [6–10] minutes, respectively; P = 0.522). When comparing the serial bleeding grade tendency, there was no statistical difference between OOZFIX and Arista AH (P = 0.656). Conclusion: OOZFIX caused a minimal FBR that disappeared within 2 weeks in vivo, and its hemostatic performance was comparable with that of an existing agent, Arista AH. Further clinical studies are required in the future.

국제 졸업컬렉션 공모전 "H&M 디자인 어워드" -2013 우승자 김민주의 사례를 중심으로-

김승아 ( Seung Ah Kim ) 한국의류학회 2015 패션정보와 기술 Vol.12 No.-