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RISS 인기검색어
- 검색키워드
- 저자 : ( Ilham Sentissi ) (검색결과 2 건)
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Electronic monitoring of medication adherence for tuberculosis treatment in Morocco: a pilot study
( Seung Heon Lee ),( Seup Park ),( Ilham Sentissi ),( Seung Jae Gil ),( Won Seok Park ),( Ah Reum Son ),( Young Ju Kong ),( Eunseong Paek ),( Yong Joon Park ),( Je Hyeong Kim ),( Chol Shin ) 대한결핵 및 호흡기학회 2015 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.120 No.-
Background: Non-adherence to treatment of tuberculosis (TB) is a major barrier to TB control. Objective:We investigated the effectiveness of Medication Event Monitoring System (MEMS) as a tailored adherence-promoting intervention for improving patients’ adherence to TB treatment in Morocco. Method: The outcome of TB treatment were compared between the patients who received MEMS and the patients who received standard TB care among patients confirmed by sputum acid fast bacilli smear. Standard TB care was based on directly observed treatment (DOT) and self-administration-treatment. Results of participants, recruited between April 2014 and August 2015, were retrospectively analyzed. The patients from 5 health centers who received MEMS (MEMS group) were compared with the patients from 7 health centers who received standard of care (control group) during same period in Morocco, Sale region. Results: One hundred three patients in MEMS group and 161 patients in control group were compared. The mean age (37.2 ± 16.3 VS. 36.1 ± 15.9) and the male-to-female ratio (73:30 VS. 111:50) were not different between two groups. The mean adherence rate in MEMS group was 94.3%. The cure rate and the completion rate in MEMS group were 33.7%, and 64.4%, respectively. Those in control group were 12.4%, and 65.2%, respectively. The default rate were significantly lower in MEMS group than in control group [1% (1/103) VS. 19.3% (31/161), odds ratio=0.04 (0.01-0.31), p < 0.01] Conclusion: MEMS could reduce the default rate of infectious TB patients in Morocco, Sale region.
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Cost effectiveness of using medication event monitoring system for tuberculosis treatment in Morocco
( In-hwan Oh ),( Jangmi Yang ),( Nathan Green ),( Seup Park ),( Ilham Sentissi ),( Byungkwon Oh ),( Won-seok Park ),( Eunseong Paek ),( Yong Joon Park ),( Je-hyung Kim ),( Chol Shin ),( Seung Heon Lee 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Background: Non-adherence to tuberculosis (TB) treatment is a barrier to effective TB control. Medication Event Monitoring System (MEMS) to enhance drug compliance based on a mobile health monitoring program instead of directly observed treatment (DOT) played a successful role in rural Morocco of North Africa. We aimed to evaluate the cost-effectiveness of MEMS for TB compared with the conventional TB treatment. Methods: The costs of TB treatment strategies were calculated using a mixed cost analysis method and expressed in 2015 US dollars. Cost-effectiveness was investigated using a decision analysis model from the health system perspective. Treatments outcomes in first-line treatment for patients with sputum smear positive, comparing MEMS with conventional group, based on a real cohort data from five health centers in the Sale area of the Rabat in Morocco (from 2014 to 2015). The incremental cost-effectiveness and disability-adjusted life years (DALY) of treating a cohort, 36-years old an average, starting from initial first-line treatment to retreatment and multidrug resistant (MDR) TB treatment adjusted by model assumption, was compared in a Markov model over a period of 5 years with 3% of discount rate. Results: The average total cost per patient in the MEMS group and conventional group was US$ 2,624 and US$ 2,770, respectively. However, the DALY was 1.148 and 1.949 in each group, respectively. The incremental cost-effectiveness ratio (ICER, US dollars/DALY averted) for MEMS compared with conventional group was 181.6 over period of 5 years, and 28.7 over 10yeras. The MEMS seems to be very cost-effective at a willingness-to-pay (WTP) threshold of US$ 3,007 when used during the initial first-line TB treatment. Conclusions: MEMS was very cost-effective, compared with the conventional method for the treatment of infectious TB patients by improving drug compliance, avoiding the retreatment or MDR treatment in Morocco.
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