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      • A comparison of survival outcome of open, total laparoscopic and laparoscopy-assisted vaginal radical hysterectomy in patients with early cervical cancer of stage IB2

        ( Sul Lee ),( Hyung Joon Yoon ),( Eun Hye Jeon ),( Juseok Yang ),( Yong Jung Song ),( Hyun Jin Roh ),( Sang Hun Lee ),( Byung Su Kwon ),( Ki Hyung Kim ),( Dong Soo Suh ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-

        Objective: The aim of this study is to evaluate oncologic outcomes of total abdominal radical hysterectomy (TARH), total laparoscopic radical hysterectomy (TLRH) and laparoscopic-assisted radical vaginal hysterectomy (LARVH) in early cervical cancer patients (stage IB2-3, tumor size≥2cm), analyzing the risk factors that may affect the clinical results. Methods: A total of 756 patients underwent radical hysterectomy between 2000 and 2019 from three university hospitals (Pusan National University Hospital, Yang-san Pusan National University Hospital, Ulsan University Hospital) were enrolled. Among them, 172 patients with stage IB2-3 were analyzed retrospectively. Results: Seventy-seven patients were treated with TARH, and 95 were managed via minimally invasive surgery (MIS), consisting of 35 with TLRH and 60 with LARVH. TARH group had better disease five-year disease free survival (DFS) and overall survival (OS) compared with MIS group (86.4% vs. 73.4 for DFS and 91.7 vs. 82.2 for OS), but not statistically significant in both (p=0.058 for DFS and p=0.119 for OS). When TARH and the LARVH group were compared, both five-year DFS and OS were not significant different (86.4 vs 82.2%; p=0.288 for DFS and 91.7 vs 84.4%; p=0.206 for OS). However, when TARH and the TLRH group were compared, TLRH group had significantly worse five-year DFS than TARH (86.4 vs 54.5%; p=0.008), but five-year OS was not significant different (91.7 vs 77.5%; p=0.127). Multivariate analysis showed that LN metastasis and TLRH surgical approaches were an independent prognostic factor for DFS in IB2-3 cervical cancers. Conclusion: Our findings provided the evidence that TLRH surgical approach was associated with worse DFS in IB2-3 cervical cancers but that of LARVH was not. Such results may have important implications of colpotomy method for MIS in cervical cancer.

      • KCI등재

        Shelf Life Determination of Precooked Frozen Meat Dumplings

        Lee, Young-Chun,Yang, Hyung-Sub,Kim, Dong-Ho 한국산업식품공학회 2002 산업 식품공학 Vol.6 No.3

        Quality of frozen foods is significantly affected by the storage temperature and tie, and the consumers' demand for safe quality frozen foods is increasing. The objective of this research was to estimate the shelf life of frozen cooked meat dumplings, based on the changes in the selected physico-chemical and sensory quality attributes. Precooked frozen meat dumplings sampled from the same lot produced at a frozen food company in Seoul were stored at -10, -15, and -20℃. The meat dumplings sampled at 3- to 4-week intervals were subjected to the determination of volatile basic nitrogen (VBN), thiobarbituric acid (TBA), peroxide value (POV), surface color and shear value after thawing at 5℃ for 15 h. High quality life (HQL) was determined through the triangle test and practical quality life (PQL) through the scoring test. VBN, TBA and POV increased as the storage period was increased. HQL of the frozen meat dumplings were 189 and 252 days at -10 and -15℃, respectively. The estimated PQL were 349, 475, and 491 days at -10, -15, and -20 ℃, respectively. Statistical analysis indicated that there were significant relationships between sensory scores and VBN and POV of the stored meat dumplings. VBN was selected as the most reliable objective quality index for the shelf life determination (PQL) of the precooked frozen meat dumplings.

      • KCI등재

        HSDPA 모뎀용 동기추적회로의 설계 및 성능분석

        양연실,박형래 한국항행학회 2003 韓國航行學會論文誌 Vol.7 No.1

        본 논문에서는 3GPP HSDPA 모뎀용 비동기식 동기추적회로를 설계하고, 설계된 동기추적회로에 대하여 정상상태 지터 분산과 타이밍 에러의 과도응답 특성을 이론적으로 분석하였다. 우선 AWGN 환경에서의 지터 분산을 펄스성형 필터, 타이밍 오프셋, 신호 대 잡음비, 루프 대역폭에 대한 식으로 유도하였으며, 과도응답특성 또한 이론적으로 해석하였다. 끝으로 설계된 동기추적회로의 성능을 컴퓨터 시뮬레이션을 통하여 확인하였다. In this paper, a non-coherent code tracking loop is designed for 3GPP HSDPA MODEM and its performance is analyzed in terms of steady-state jitter variance and transient response characteristics. Analytical closed-form formula for steady-state jitter variance is first derived for AWGN environments as a function of pulse-shaping filter, timing offset, signal-to-interference ratio, and loop bandwidth. Also obtained is the transient response characteristic of a tracking loop. Finally, the performance of the designed tracking loop is confirmed by computer simulations.

      • KCI등재

        데페록사민 전처치가 토끼 심근경색 크기의 감소에 미치는 효과

        양관모,오동렬,박승현,박규남,이원재,김형국,황두영,최승필,채장성 대한응급의학회 1998 대한응급의학회지 Vol.9 No.4

        Background: Reperfusion of ischemic myocardium has been postulated to result in a specific oxygen radical mediated tissue injury. Iron may liberate during ischemia and we hypothesized that administration of the iron chelator, deferoxamine during ischemia would result in improved recovery after postischemic reperfusion. Purpose: To test whether iron-catalyzed processes contribute to myocardial necrosis during ischemia and reperfusion, deferoxamine was administered to block iron catalyzed hydroxyl radical formation in rabbits. Methods: Eleven rabbits were divided into two groups : control group (n=5) and deferoxamine pretreatment group (n=6). The left circumflex coronay artery was ligated for 30 minutes and reperfused for 180 minutes. Area at risk (AR) was measured by non-stained area with methylene blue injection into left atrium after left circumflex coronary artery ligation. Infarct size was measured by weighing after triphenyltetrazolium chloride staining. Heart rate was measured using electrocardiographic recording and systemic blood pressure was monitored by pressure transducer connected to the catheter in the left ventricle. Results: 1. There was no significant difference of heart rate and blood pressure in deferoxamine pretreatment group compared with control group. 2. There was significant decrease of serum iron concentration after continuous infusion of deferoxamine compared with serum iron concentration before ligation of coronary artery(P<0.05). 3. There was no significant difference of area at risk between control and deferoxamine pretreatment group. 4. Area at necrosis to area at risk was significantly reduced in deferoxamine pretreatment group compared with control group(P<0.05). The results suggest that deferoxamine infusion prior to coronary artery occlusion has a significant benefit in reducing infarct size in this model.

      • 유세포 측정을 통한 CD34^(+)세포의 정량방법 비교

        양형모,서영훈,엄현석,민창기,김희제,정대철,이종욱,진종율,한치화,김춘추,김학주 대한조혈모세포이식학회 1998 대한조혈모세포이식학회지 Vol.3 No.2

        본 연구소에서는 현재 CD34^(+) 세포의 정량에 사용되고 있는 4가지 서로 다른 방법을 가지고 골수에 적용하여 그 결과를 비교하였다. 각각의 방법들이 편리한 점과 불리한 점들을 가지고 있었지만, 통계적으로는 유의한 차이를 보이지 않았다. 1) CD34-PE/CD45-FITC 방법13(ISHAGE: International Society of Hematotherapy and Graft Engineering), 2) CD34-PE/CD14-FITC 방법, 3) CD34-PE/CD14-FITC/CD45-PerCP 방법, 4) DNA dye/CD34-PE/CD45-PerCP4(Becton Dickinson) 등을 비교하였으며 그 결과 CD34^(+) 세포의 농도는 다음과 같았다. 1) 0.473±0.345, (%Mean±SD, N=70) 2) 0.663±0.519, (N=20), 3) 0.543±0.381 (N=46), 4) 0.624±0.341, (N=32). 시료로는 여의도 성모병원 카톨릭 조혈모세포이식 센터에서 채혈한 골수를 이용하였다. Four different methods for flow cytometric quantitation of CD34+ cell were compared using bone marrow samples (n=168). Following combination of antibodies were used for the analysis : A) CD45-FITC/CD34-PE (n=70), B) CD14-FITC/CD34-PE (n=20), C) CD14-FITC /CD34-PE /CD45-PerCP(n=46), D) DNA dye/CD34-PE/CD45-PerCP (n=32). Each method showed no significant differences among them (P=0.126, ANOVA test, SPSS Version 7.5). When we compare these methods using same samples (n=12), the P value became 0.832. The mean % of CD34+ cells calculated in this experiment were A) 0.474%, B) 0.663%, C) 0.548%, D) 0.624% respectively. In our laboratory, we decided to use CD45-FITC/CD34-PE methods as a routine protocol.

      • 서비스 공정성이 학생 만족도에 미치는 영향에 관한 연구 : 대구 D 대학 재학생을 중심으로 In Context of Students of Daegu D College

        양승복,이형백 대구보건대학 2002 대구보건대학 論文集 Vol.22 No.-

        The purpose of this study is to understand the critical role of customers' perceived service justices in relationship marketing. This paper examined the relationships of service justices with relationship quality and student satisfaction, and investigated the effects of relationship quality and satisfaction on student' voluntary behaviors in a social exchange perspective. Data were collected from 190 collage students at a private university located in Taegu, Korea. The empirical results indicated that distributive justice, procedural justice and interactional justice takes strong effect on student satisfaction.

      • KCI등재

        항정신병약물로 야기되는 초과민성 정신병에 관한 연구

        양동균,윤진상,이형영 大韓神經精神醫學會 1989 신경정신의학 Vol.28 No.2

        Chronic antipsychotic treatment can induce tardive dyskinesia and supersensitivity psychosis, and these may be explained by supersensitivity phenomena of the dopamine receptor in the brain. This study was conducted to compare the clinical characteristics between tardive dyskinesia and supersensitivity psychosis in schizophrenia. The subjects of the study were composed of 8 schizophrenics with tardive dyskinesia(TD ), 10 schizophrenics with supersensitivity psychosis(SP), and 5 schizophrenics with both syndromes(TD with SP). They all had been treated with antipsychotics. We compared the difference in general and antipsychoti-related characteristics among the three groups. The results are as follows : 1) In the comparison of general characteristics ; There was a significant difference in the number of hospitalizations among the three groups. The number of hospitalizations was most frequent in SP group, and this was followed by TD with SP group(P<0.05). There was also a significant difference in the length of hospitalization : the longest in SP group and the shortest in TD group. Among the schizophrenic subtypes by Andreason-0lsen's criteria, the number of positive schizophrenics were significantly greater in SP and TD with SP group than in TD group(P<O.05) . 2) In the comparison of antipsychotic-related characteristics : There was a significant difference in the current antipsychotic dose among the three groups. The current antipsychotic dose was highest in SP group and this was followed by TD with SP group(P<0.05). The therapeutic response to antipsychotics was significantly better in SP group than in TD group, and the serum prolactin level was significantly higher in SP group than in TD group, and the serum prolactin level was significantly higher in SP group than in TD group(P<0.05; respectively) 3) Regardless TD, if SP was present, the serum prolactin level was significantly correlated to the current antipsychotic dose(P<0.05). 4) But, there was no significant difference in mean age, age of onset, duration, schizophrenic subtype by DSM-Ⅲ criteria, duration of antipsychotic treatment, prognosis, and antipsychotic potency among the three group.

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