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      • 커패시터 放電 임펄스 着磁機 및 着磁 요크시스템의 定數算定에 관한 硏究

        白壽鉉,金 龍,金必洙,尹秀鳳,朴永浩,尹信容 동국대학교 대학원 1992 大學院硏究論集-東國大學校 大學院 Vol.22 No.-

        In a capacitor-discharge impulse magnetizer, a magnet is magnetized by the discharging current of capacitor The actual construction of magnetizing fixtures and discharge matching is expensive and time-consuming. Since the parameters of the impulse magnetizer have been determined and the resistance and inductance of such a magnetizing fixture can be easily computed using FEA, it is possible to predict the performance of such a fixture without actually building it. This paper describes that by mathematically modeling the capacitor-discharge impulse magnetizer fixture the problem can be solved with resonable predictability. The basic equations are presented and used to predict the magnetic-field intensity inside the fixtures. Finite-Element-Analysis is also used as part of the design process

      • Benzo(a)pyrene에 의해 유도된 간기능 장해에 미치는 당귀의 효과

        윤수홍,조수열,이윤경,하두현 한국환경독성학회 1992 환경독성보건학회지 Vol.7 No.1

        This study was performed to investigate the effect of Angelicae gigantis Radix extract on the hepatic detoxifying enzyme activities and lipids. Male sprague-dawley rats were administrated the extracts with benzo(a)pyrene, a hepatotoxic agent, inducing liver damages. Results obtained from this study were as follows: 1. The markedly increased enzyme activities (AST, ALT, LDH, ALP, γ-GTP, GSH -Px) in B(a)P induced groups tended to be decreased by the treatment of the Angelicae gigantis Radix extract. 2. Liver GSH content and lipid peroxide activity were decreased by the administration of the extracts. 3. It tended that the curative effects were better than the protective effects of the extracts.

      • KCI등재

        3단 및 변형 2단 카세트 샘플러의 공기중 수산화나트륨 포집효율의 실험적 연구

        윤영식,김치년,김현수,노재훈 한국산업위생학회 2002 한국산업보건학회지 Vol.12 No.1

        Sodium hydroxide(NaOH) is one of the chemicals produced great quantity in Korea. It variously uses for acid neutralization, petroleum refining, electroplating, metal cleaning, laundering, bleaching, washing dish, manufacture of paper, etc. NaOH is used in various field of industry but information on the sampling efficiency for NaOH IS seldom provided. The objective of this study was to compare the sampling efficiency of the three-piece cassette sampler with the modified two-piece cassette sampler. The three-pieces cassette consisted of an inlet cover, a spacer, a mixed cellulose ester membrane(MCE) filter, a back-up pad and a bottom. The modified two-pieces cassette consisted of the same parts as a three-piece cassette without a spacer. The whole inner surface of the 2-piece cassette was loaded with MCE filter to ensure that all of the aspirated NaOH. The air sampling of airborne NaOH WAS performed according to the Occupational Safety and Health Administration(OSHA) analytical method manual ID-121 that is used for the method of occupational environment measurement and analysis. Air samplings were per-formed by simultaneous samplings using the three-piece and modified two-piece cassette sampler at the same time and same place in the chemical plants. The significant difference between average adsorbed amounts on the MCE filters of the three-piece and modified two-piece cassette sampler was found. Sampling amounts of the modified two-piece cassette sampler was 1.84 times higher than that of the three-piece casstte sampler(p<0.01). An average 47% of NaOH was collected on the upper (inlet+middle-rim) side of the modified two-piece cassette. As the result of his study, it is verified that the modified two-piece cassette sampler is more effective than the three-piece cassette sampler for collection of airborne NaOH.

      • 화학적 간장해에 대한 시호와 황금의 보호효과

        윤수홍,오관현,하헌 대구효성카톨릭대학교 1997 연구논문집 Vol.56 No.2

        In oriental medicine several valuabel prescriptions for hepatic diseases usually contained the Bupleuri Radix and Scutellariae Radix. The possible protective effect of these oriental herb on hepatotoxicity induced with benzo(a)pyrene(B(a)P) in vivo were examined. Water extracts of Bupleleuri Radix, Scutellariae Radix and the mixture of both Radix were separately administered by orally to rats with hepatic demage induced by B(a)P(0.1 mg/kg, i.p.) and their effects in the serum were biochemically investigated. B(a)P treated group had siginificantly increased AST, ALT, ALP and LDH activities of Radix, Scutellariae Radix significantly diminished these increased enzyme activities. Increased total lipid, triglyceride and total cholesterol contents of serum by B(a)P injection were decreased by administration of water extract of Bupleuri Radix, Scutellariae Radix and mixture. Favorable results of this experiments indicate that herb mixture can be considered as a good therapeutic agent for the treatment of hepatic injury.

      • 農家所得增大를 위한 보리쌀 消費增大方案에 관한 硏究 : 보리쌀 炊飯特性 硏究를 통한 보리 利用性 提高方案

        尹水弘,徐挺植,金尙玉,玄仁煥 영남이공대학 1981 論文集 Vol.10 No.-

        This study was carried out as a program to increase the utilization of barley by improving the acceptable eating quality of Korea's traditional cooked barley of a grain type. The barley's characteristics of cooking and acceptable eating quality according to its pearling rate by pearling it differently in the four classes; 70%, 60%, 50%. 45% (as the weight ratio of pearled barley to covered one) were examined extensively including the general compositions of samples, the time course changes of barley's volume and weight in proportion to the soaking before cooking, the experiments of the physiochemical characteristics (the water-uptake ratio and swelled volume of polished barley when cooked, the pII, iodine color intensity and total solids in the residual cooking liquid) and textural properties by the universal testing machine about the cooked barley as a objective testing method of acceptable eating qualities, the sensory evaluation of cooked barley as a subjective testing method of acceptable eating qualities, etc. The results were as follows: 1. According to the decrease of pearling rates, moisture contents and nitrogen-free extracts of samples were increased slightly, but their components of crude protein, crude lipid, crude fibre and ash were decreased greatly 2. In the time-course changes of the capacity of water-uptake and swelling of volume according to the soaking of samples before cooking, the increased weight ratios were increased in proportion to the decrease of pearling rate of barley, but the increased volume ratios were increased according to the order of covered barley, Akibare(rice), 50% pearled barley, 60% pearled barley, 70% pearled barley, 45% pearled, ane especially the volume increases were marked at the early stage of soaking in 70% pearled barley. 3. According to the decrease of pearling rate, water-uptake ratios during cooking were increased, but swelling of volume had the maximum value at 60% pearled barley, decreased again having the minimum value at 45% pearled barley. 4. pH values of the residual cooking liquid of the cooked barley were decreased according to the decrease of pearling rate and were considerably less than the pH, 6.46 of Akibare. The iodine color intensity and total solids of the residual cooking liquid of the cooked barley were increased greatly according to the decrease of pearling rate, but were considerably lower as compared with those of Akibare as a whole. 5. The texture profile of the cooked barley obtained by the universal testing machine were analyzed by the methods of Bourne. Henry etc. Max. force known to hardness, force to 20% compression, compressive gumminess, compressive chewiness were increased according to the order of pearling rate, 60%, 50%, 45%, 70% and recorded the higher values as compared with those of Akibare. Compressive cohesiveness, peak force, tensile hardness, tensile springiness, tensile cohesiveness, tensile gumminess, tensile chewiness were increased according to the decrease of pearling rate of barley and reached the maximum at 45% pearled barley, but recorded the much lower values as compared with those of Akibare. But springiness did not show some differences between the pearling rates or rice and barley polished. 6. According to the results of panel tests about the cooked barley by the hedonic scoring method based on a 5-point scale, color, tasts, appearance, adhesiveness, total acceptability had significant differences between samples at 95% level, but other quality factors did not and there were no significant differences between panel members. The means of total scores increased according to the order of pearling rate. 60%. 70%, 50%, 45%, and therefore it was shown that 45% pearled barley had the best acceptable eating quality.

      • 머리염색이 인체에 미치는 영향

        윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

        일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.

      • SCOPUSKCI등재
      • Butane gas가 흰쥐 혈청과 조직의 Lactatedehydrogenase 및 Cholinesterase에 미치는 영향

        윤수홍,박은주,조수열,최현태 한국환경독성학회 1991 환경독성보건학회지 Vol.6 No.2

        Acute poisoning with organic solvents and other volatile compounds now usually follows deliberate inhalation (volatile substance abuse) or ingestion of these compounds. The effect of butane gas inhalation was analyzed for serum, liver, brain, lung and muscle. And the observations are revealed on rat cholinesterase activity, lactatedehydrogenase activity and electrophoretic pattern of lactatedehydrogenase isozyme. The results are as follows: 1. The rat cholinesterase activity on serum, liver and muscle show the decreased by increasing of inhalation time of butane gas in particular the lung cholinesterase activity was greatly affected. 2. Butane gas inhalation brought out the lactatedehydrogenase activity increased of the serum and the tissues and had an important effect especially in both the liver and muscle lactatedehydrogenase activities. 3. Each tissue was found to have a characteristic distribution of lactatedehydrogenase isozymes on celluloseacetate electrophoresis and the development of inhalation time is shown the disappearance and diffusion of band. The toxicity of butane gas inhalation was most prominence in the liver and lung toxicity was occurred also.

      • KCI등재후보
      • 천연자원을 이용한 간기능 증진제 개발 연구 : Benzo(a) pyrene에 의해 유도된 간기능 장해에 미치는 세신 추출액의 영향 The Effect of Asiasari Radix on Benzo(a)pyrene Induced Hepatotoxicity

        윤수홍,박은주,오관현 효성여자대학교 부설 한국환경위생연구소 1994 환경위생연구 Vol.4 No.1

        Effect of Asiasari Radix, which is a herbal drug used frequently in the oriental prescriptions, water extract on the liver-protective activities were investigated in the rats. Asiasari Radix extract, when administered into the gast-ric intubation, produced liver-protective effect against benzo(a)pyrene induced liver damage. The results obtainedfrom liver microsomal enzyme assay, measurement of serm and liver alanine·aspartate aminotransferase and lipid accumulation, indicated that alismatis extract showed significant liver-protective activities agai-nst benzo(a) pyrene poisoning.

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