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김한석,김명래,이성근,강상원,김기환,김형섭 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.1
Objective : This is to report the effectiveness of intraoral distraction osteogenesis for alveolar augmentation in the extremely atrophied alveolar defects and to review the clinical results of the 2 cases. Subjects and Methods : Anterior segmental osteotomy was performed and the trans-oral alveolar distractors(Martin, Germany) were applied in 2 patients with the severe acquired anterior maxillary and mandibular defect. After latent period for 1 week, the osteomized alveolar segments were distracted by 1 ㎜ a day (0.5 ㎜/l turn) for 8 days in case Ⅰ and 0.6 ㎜ a day(0.3 ㎜/l turn) for 10 days in case Ⅱ. The consolidation period was about 8 weeks in each case. Thereafter, 6 titanium threaded implants(Branemark, Restore) were simultaneously installed with removal of distractor. The implants were tested clinically and radiographically. Results : Amounts of acquired alveolar bone were 8 ㎜ in case Ⅰ and 6 ㎜ in case Ⅱ respectively, with the increased width of the ridge crests and soft tissue expansion. Dental implants installated on the augmented alveolar ridges in 8 weeks after distrction were confirmed as in good osseointegration and in good function without any complications. Conclusion : Intraoral distraction osteogenesis can be a good option for alveolar ridge augmentation of the severely atrophied ridges and soft-tissue defects. However, for the better vector control of distracting segments and for anterior esthetics, customized distraction devices could be considered later.
k-ε 모형에 의한 2차원 균질분류장의 해석에 관한 연구
김기홍,이형래 진주산업대학교 건설기술연구소 1998 건설기술연구소보 Vol.1 No.-
A numerical study on the homogeneous jets has remained of requiring more intensive investigation for problems due to the treatments of free surface, Reynolds stress /flux terms in turbulent flow. The verification of predicted results from the numerical study continues to be in the qualitative study, because of the lack of experimental data, due to the difficulties in measuring the turbulent fluctuations in flow. In this study, the computer program of k-ε model being widely used for the simplicity of computation has been developed to compute the characteristics of two-dimensional homogeneous jets with the free surface boundary condition. By comparing these results with Gaussian distribution, it is found that this model can predict fairly well the characteristics of two-dimensional homogeneous jets in the momentum region.
김기흥,류근상,신영철,이형래 진주산업대학교 산업과학기술연구소 2004 산업과학기술연구소보 Vol.- No.11
In order to evaluate six formula of T_(c) presented in the facilities criterion of small basin, the water stages were observed on fifteen mountainous small basin in Sanchung county region. The results of six formula compared with the observed data to evaluate T_(c). All basin area were less than 2.25 ㎢. The average basin area was 1.19 ㎢, the average basin length was 1.65 ㎢, the average basin slope was 6.95%, average length and slope of main channel were 1.86 ㎞ and 7%. The average T_(c) was 33.77 minutes and results of six formula showed the changes in average and standard deviation widely. The conclusions obtained in this study are as follows. The time of concentration was influenced basin slope, basin length, basin slope and channel slope consequently but did not affected the shape factor of basin.
Visible Human Data의 3차원 가시화에 대한 연구
최형근,김동현,탁계래,신현준 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-
Visualization is the process of exploring, transforming and viewing data as images to gain understanding and insight into the data. Visualization in medicine is helpful in understanding human anatomy by presenting the information in a form that is not only pleasing but also easily recognizable as well as in gaining functional attributes of medical systems, such as biomechanical and physiological properties. Medical applications include accurate anatomy and function mapping, enhanced diagnosis. accurate treatment planning and rehearsal, and education/training. The Visible Human data set of the National Library of Medicine, the most complete anatomically detailed. computerized database of the human body ever assembled, has been used for these purposes. In this study, we have visualized the Visible Human Data set with VTK(Visualization ToolKit, Kitware Inc.), IAP(Image Application Platform, ISG Inc.) and Visual C++ 6.0. A motivation of this study is the fact that computer imaging techniques have become an important diagnostic tool in the practice of modern medicine. The 3D visualization system consists of a basic 2D image processing such as filtering, panning, zooming and measuring image as well as 3D image processing such as multiplanar reformatting, surface rendering and volume rendering. The wide-spread use and accessibility of the web have been required to provide the visualization of 3D image on the web. Thus, we have developed web-based medical 3D visualization system that supports World-Wide-Web using VRML and client/server architecture.
Kim, Hyeong Rae,Park, Ji-woon,Kim, Hyung Sun,Yong, Dongeun,Hwang, Jungho Pergamon Press 2018 Journal of aerosol science Vol.115 No.-
<P><B>Abstract</B></P> <P>Impactor is a widely used air sampling device because of it is relatively inexpensive and easy to use for sampling bioaerosols. However, sensitive microorganisms may have significant mechanical stress by inertia impaction. Therefore, this sampling method can underestimate the concentration of airborne bioaerosols. Electrostatic sampling can be a good alternative method for bioaerosol sampling because of a less stressful collection technique and has been frequently used. However, it is well known that ions and ozone generated by corona discharge can also inactivate the bioaerosols. In this study, the performance of our lab-made electrostatic rod-type sampler was compared with that of a single stage viable impactor (TE-10–880, Tisch Environmental, USA). The flow rate of our electrostatic sampler was determined so that the number of aerosols collected using the electrostatic sampler would be same as that of aerosols collected using the impactor of which flow rate was 28.3 lpm. After counting the colony numbers of bacteria captured using two different samplers, each cultured colony was identified with Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) at indoor environment. The total number of identified bacterial genus was 17. Among 17 bacterial genuses, 15 genuses were identified when the electrostatic sampler was used while 9 genuses were identified when the impactor was used. In common, 7 genuses were detected from both samplers. 5.2 folds concentration of bacteria were cultured when the lab-made electrostatic rod-type sampler was used.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Same number of bacteria was sampled for both electrostatic sampler and impactor. </LI> <LI> Some genuses of sampled bacteria could be detected or undetected, depending on sampling method. </LI> <LI> 15 genuses were identified using the electrostatic sampler while only 9 genuses were identified using the impactor. </LI> </UL> </P>
A case of actinic keratoses and squamous cell carcinomas treated with ingenol mebutate gel
( Hyeong Rae Kim ),( Hae Eul Lee ),( Myung Im ),( Young Lee ),( Jeung Hoon Lee ),( Young Joon Seo ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Chronic skin exposure to ultraviolet irradiation causes well-known phenomenon called photodamaging and skin cancer and precancerous lesions like actinic keratosis (AK) develop on severely damaged area. The concept of filed cancerization, first introducd in 1953, is adopted by dermatologists to describe chronically photodamaged skin with multiple AK and skin cancers. For the treatment of both clinical and subclinical lesions, not lesions-directed therapy but field-directed therapy is advocated and which include photodynamic therapy and topical agents such as imiquimod, 5-fluorouracil and topical diclofenac. Ingenol mebutate gel is recently induced topical agent from plant Euphobia peplus and there have been no case report treated with this new agent in Korean literature. A 72-year-old man presented with extensive erythematous scaly lesions on his face and both distal upper extremities. Histopathologic examination showed actinic keratosis and squamous cell carcinomas. Two sessions of topical treatment was done and more than 80% of lesions disappeared after 5 months follow-up. There was moderately severe local reaction transiently after treatment.
Effects of β-Glucan from Aureobasidium pullulans on Acute Inflammation in Mice
Hyeong-Dong Kim,Bok-ryeon Park,Hee-Jeong Jang,Lin-Su Kim,Hyeung-Sik Lee,Sae-Kwang Ku,Hyung-Rae Cho,Seung-bae Moon,Hyun-Dong Shin,Kun-Ju Yang 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.3
The effects of β-glucan isolated from Aureobasidium pullulans were observed on acute xyleneinduced inflammation. β-glucan at a dose of 62.5, 125 or 250 mg/kg were administered once orally to xylene-treated mice (0.03 mL of xylene was applied on the anterior surface of the right ear to induce inflammation), and the body weight change, ear weight, histological profiles and histomorphometrical analyses of ear were conducted upon sacrifice. The xylene was topically applied 30min after dosing with β-glucan. The results were compared to those of diclofenac, indomethacin and dexamethasone (15 mg/kg injected once intraperitoneally). All animals were sacrificed 2 h after xylene application. Xylene application resulted in marked increases in induced ear weights compared to that of intact control ear; hence, the differences between intact and induced ear were also significantly increased. The histological characteristics of acute inflammation, such as severe vasodilation, edematous changes of skin and infiltration of inflammatory cells, were detected in xylene-treated control ears with marked increase in the thickness of the ear tissues. However, these xylene-induced acute inflammatory changes were significantly and dose-dependently decreased by β-glucan treatment. We conclude that β-glucan from A. pullulans has a somewhat favorable effect in the reduction of the acute inflammatory responses induced by xylene application in mice.
Squamous cell carcinoma arising from porokeratosis of Mibelli
( Hyeong Rae Kim ),( Hae Eul Lee ),( Myung Im ),( Young Lee ),( Jeung Hoon Lee ),( Young Joon Seo ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Porokeratosis is an epidermal keritinization disordercharacterized clinically by raised hyperkeratotic border and histologically by the presence of cornoid lamellae. Several clinical variants have been recognized and development of squamous cell carcinoma (SCC) in lesions has been reported in all variants. Risk of malignancy is associated with older age, longstanding duration and linear variants. We report a case of SCC arising from porokeratosis of Mibelli. A 80-year-old woman presented with erythematous scaly plaque for 13 years. Physical examination showed erythematous scaly plaque, 5 x 6 cm in diameter, on left knee. After diagnosis of Porokeratosis was made, isotretinoin cream, calcipotriol ointment, and oral acitretin was prescribed, but lesions did not reached complete remission and has wax and waned. Ulceration with mass formation occurred after 4 years of initial diagnosis. Tumor excision was performed and histopathological examination showed a squmamous cell carcinoma with keratination. Excised margin was negative for tumor cells and patient was follow-up for additional 6 months without recurrence of the cancer.