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서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)
김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3
Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.
저혈청 배지에서 인간 전골수세포(HL-60)를 이용한 tPA 생산과 세포사멸기작에 관한 연구
김현구,성기돈,김태호,안주희,함문선,박진서,이현용 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1
tPA 생산과 세포 사멸의 연구를 하기 위해서 인간 전골수세포가 배양되었다. 연속 관류 배양하에서 최대 tPA 생산량은 324 ng/ml이며 최대 세포 농도는 5.27×10 exp (6) cells/ml였다. Phorbol ester를 넣었을 때 tPA 생산량은 420 ng/ml까지 향상되었다. 형광 현미경으로 관찰했을 때, apoptosis는 세포 배양 초기부터 중반까지 우세했고 빠른 교반 속도에서도 우세했다. 그러나 necrosis는 세포배양 말기와 동결된 세포가 해동 되었을 때 우세했다. HL-60 was cultivated to produce tPA (tissue-type plasminogen activator) and study the mechanism of cell death. Maximum cell density and tPA production were obtained as 5.27×10 exp (6) cells/ml and 324 ng/ml, respectively under perfusion cultivation. tPA production was enhanced to 420 ng/ml in adding 160 nM of phorbol ester. The cells were gradually differentiated to granulocytes rather than proliferation. By Fluorescent microscope, apoptosis was prevailed except the death phase and in high agitation speed, but necrosis was prevailed in thawed cells and during the latter periods of the cultivation. It was also proved that tPA was most produced in apoptosis. To obtain higher tPA productivity, the cells must be maintained in apoptosis, not necrosis phase when the cells were dying.
홍소현,김도연,김태오,배지윤,이신아 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.S
자발성 신파열은 외상 혹은 수술 등의 병력 없이 신장 피막 혹은 신장 주위 혈종이 자발적으로 발생하는 드문 질환으로, 원인으로는 요로 결석[1], 결핵, 신우신염, 신농양 같은 감염성 질환이나[2] 신장의 종양 및 신장 이식 수술 후[3], 후천성 낭성 신환[4] 등이 관련이 있다. 그 중 복막 투석 환자에서 낭성 신질환에 의한 자발성 신파열은 국내 보고가 있었으나 요로감염에 의한 자발성 피막하 혈종을 동반한 신파열은 문헌 보고가 없었다. 저자들은 요로감염으로 진단된 환자에서 피막하 혈종을 동반한 신파열 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.
김현태,이상무,어수택,박춘식,정성환,허승재,남충희,강창희,김용훈 순천향대학교 1994 논문집 Vol.17 No.4
We analysed 404 patients with primary lung carcinoma who were treated at Soonchunhyang University Hospital from July, 1985 to september, 1993 in order to investigate the survival rate and epidemiolgical properties of primary lung cancer. They were 330 males and 74 females. The most prevalent decade was seventh. In terms of cell type, the squamous cell was 225 patients (55%), and adenocarcinoma, small cell, mixed type was 21%, 19%, 4%, respectively. Among non-small cell lung carcinoma, stage Ⅲa was the most prevalent one(92%). In case of small cell carcinoma, the limited stage was 64%. The 12-, 24-, 36- month survival rate of total patients was 57%, 31%, 22%, respectivley and median sruvival time was 15 months. The 36-month survival rate tended to be longer in non-small cell lung carcinoma than that of small cell lung cancer, but there was no difference between two groups, statistically. In non-small cell carcinoma, The 36-month survival rate and meidan survival time were longer in the stage Ⅰ and Ⅱ than those of Ⅲa, Ⅲb, Ⅳ (80% versus 38%, 22%, 0%, p<0.05). According to involvement of lymph node, the 36-month survival rate was longer in NO and N1 than those of N2, N3 (61.9%, 48.7% versus 17.7%, 17.3%, p<0.05). In small cell carcinoma, The 36-month survival rate and median survival rate were higher and longer in limited stage than those of extensive stage(16.1% and 13 month vs 10% and 8 month, p<0.05). In conclusion, we report here the incidence of primary lung carcinoma and the survival rate of paients with primary lung carcinoma who were treated in Soonchunhyang University Hospital.
김정태,황현식 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1
The purpose of this study was to evaluate the changes of occlusal contact in the first year following orthodontic tooth movement, and further find out the time of occlusal stabilization after orthodontic appliance removal. The sample consisted of twenty orthodontic patients who had been treated with edgewise appliances. Occlusal contacts in maximum intercuspation were recorded using silicone-based impression material at the time of the removal of orthodontic appliance and 1, 2, 3, 4, 5, 6, 9, and 12 months after the appliance removal. After all the occlusal contacts were evaluated and classified as either true or near contacts, the numbers of each contact were recorded. Each interocclusal record was then transferred to the study model, and the changes in the location of the occlusal contact were compared and analyzed. Through the statistical analyses, the following results were obtained. 1. The number of occlusal contacts showed an increasing pattern with a linear trend during the period of this study. 2. The number of occlusal contacts showed the most steep increasing pattern for one month after appliance removal. 3. There was no significant increase in the number of occlusal contacts after 6 months following orthodontic tooth movement. 4. When it was compared with changes in location of occlusal contact, the number of contacts which migrated toward central fossa was greater than that of contacts which migrated away from central fossa till 6 months after appliance removal. The above results suggest that occlusal stabilization following orthodontic tooth movement mostly occurs within the 6 months after appliance removal and mechanical retention is required during this period.
김수자,송태현 이화여자대학교 이화인문과학원 2010 탈경계 인문학 Vol.3 No.3
For some years, there have been widespread and on-going discussions over the issue of globalization from various perspectives. Some take a positive view of the issue, saying that globalization, in the end, benefits all of us; others take a defensive stance against globalization, defining it as imperialist invasion. The same goes for the cultural globalization issue. Some argue that unless we make efforts to preserve our local culture, our cultures will be homogenized into one dominant global culture, and our cultural objects will become mere commodities in the global market with the trend of cultural imperialism. Others welcome globalization as benefiting cultural diversity, greatly esteeming the willingness of local cultures to embrace the larger global culture and assimilate into it. With our world globalizing, we are witnessing the phenomena of cultural homogenization as well as cultural heterogenization and cultural pluralism, all at the same time. In this context, the concept of glocality becomes very significant because glocalization, a combination of the terms "global" and "local," can serve as an alternative to globalization. Instead of local cultures becoming objects assimilated into global culture, glocalization may enable local cultures to better understand different cultures of the world. McDonald’s, a leading global brand, has become a symbol of globalization in cultural and economic contexts. McDonald’s, at the same time, represents glocalization with its regionalization efforts accommodating local cultures as it expands into many international markets. Since 1997, McDonald’s in Korea has been adapting to local Korean culture, offering a regionalized version of its menu, such as the Bulgogi Burger and the Shrimp Burger, to satisfy the palate of the Korean people. This wouldn’t have been possible without a deep understanding of Korean culture as well as of the sentiments of Koreans. As a multinational corporation, McDonald’s clearly saw the importance of keeping up with the current trends of local culture, communicating effectively inter-culturally, and implementing cultural regionalization strategically. Yet, on a closer look, we see the phenomenon of McDonald’s glocalization efforts as only superficial. In other words, McDonald’s regionalization efforts were made only for the purpose of making maximum profits in the market, without genuine interest in going local. Therefore, in research on glocality, we need to explore how two important issues of the preservation of local culture and the integration into global culture can go hand in hand and how a new paradigm of glocalized culture can be created.