한강수계분지내 하천수의 지구화학적 특성

서혜영,김규한 이화여자대학교 환경문제연구소 1997 이화환경연구 Vol.1 No.-

한강 수계 분지 내의 하천수 (지표수)와 서울 지역 지핫의 화학적 특성 규명과 용존 이온종의 기원을 연구하기 위해 1996년 3월-4월 동안 하천수 시료 60개에 대하여, pH, TDS 등과 용존이온의 화학분석을 실시하였다. 남한강과 북한강 하천수의 화학성분은 주로 수계분지 지역에 분포하는 암석에 의해 영향을 받고 있으며, 한강본류의 하천수는 인위적인 오염에 의한 영향이 크게 나타나고 있다. 즉, 남한강은 상류지역에 분포하는 탄산염암, 탄광 및 금속광산 폐수등에서 용출된 Ca(), Mg(), HCO(), SO() 등이 현저하며 북한강은 화강암질암의 풍화 산물인 K(), Na(), Ca()등의 이온종이 특징적이다. 한편 양수리에서 상기 2개 하천이 합류하여 서울 도심을 지나는 한강 본류는 SO(), NO(), PO(), Cl()등 생활하수 오염의 영향이 현저하게 나타나고 있다. 한강 본류로 유입되는 서울 지역의 왕숙천, 탄천, 중랑천, 안양천의 4개의 지천은 NO(), Cl(), PO(), SO(), Mn등 인위적인 오염현상이 크게 나타나고 있다. 한강 하천수의 화학 성분의 군집, 요인 및 회귀 분석 결과, 전체 자료 분산은 오염 인자에 의한 분산이 약 79%, 지질과의 물-암석 반응에 의한 분산이 약 7%이다. 남한강과 북한강의 합류 지점에서의 Cl에 대한 혼합 비율은 약 60:40이다. 1981년 분석 자료와 1996년 자료의 비교에서 암석 풍화에 의한 1차적 용존 성분인 Ca(), Mg(), HCO()등은 변화가 적으나 Na(), NO(), PO(), SO()등 인위적 오염원의 성분은 크게 증가하는 경향이 있다. To investigate geochemical characteristics and the sources of the dissolved ion species in the river water in the Han river drainage basin, samples were collected at 60 sites from the Han river drainage basin. The data for pH, conductivity, TDS(total dissolved solid), temperature, and concentrations of dissolved ions were obtained as follows:(1) The geochemical characteristics of the surface water in the South and North Han river drainage basins are mainly controlled by bed rock geology in the drainager basin and in the main stream of the Han river considerably affected by anthropogenic pollution. The South Han river water samples have high concentration of Ca() (ave. 15.42ppm), Mg()(ave. 2.74 ppm), HCO()(ave 51.9ppm), which evidently indicates that the bed rock geology in a limestone area mainly controls the surface water chemistry. The concentration of SO() is remarkably high(SHr10-2:129.9ppm) because of acid mine drainage from the metal and coal mines in the upper reaches of the South Han river. (2)The South Han river and the North Han river join the Han river in the Yangsuri, Kyounggido and flow through Seoul metropolitan city. The mixing ratio is about 60:40 at the meeting point(sample number HR10). (3)The result of factor analysis suggests that the pollution factor accounts for about 79% and the bed rock type factor accounts for about 7% of the data variation. This means that the geochemical characteristics of the Han river water mainly controlled by anthropogenic pollution in the South Han river and main stream of the Han river drainage basin. (4)The chmical data for four tributaries such as the Wangsukcheon, the Tancheon, the Zungrangcheon, and the Anyangcheon show that the concentration of pollution elements such as NO(), Cl(), PO(), SO() and Mn are high due to municipal waste disposal.

‘병동 중심의 처치수가 산정지침 개발’ 등을 통한 간호업무 표준화 및 그 효과

한혜정,설미진,김영주,박소영,박아리스,문한경,이현영 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.1

문제: 병동 처치수가 산정 부정확 및 누락으로 인한 부적절한 재고관리로 진료차질, 불필요한 업무발생 및 수익이 감소한다. 목적: 병동 처치수가 산정 정확화를 위한 업무 표준화 도구 및 시스템을 개발하여 적정 재고관리를 통한 수익증대 및 직무만족도를 향상시킨다. 의료기관: 서울시 종로구에 소재한 대학병원 질 향상 활동: 병동중심의 처치 산정지침 개발 및 수가물품의 적정재고 관리방안을 모색하였다. 개선효과: 병동중심의 처치수가 산정 지침서를 제작하여 업무표준화를 기하였음. 응급청구 품목 및 수량이 ’07년 대비 71%감소하고 타 병동 차용품목이 활동 전에 비해 61% 감소, 수량은 77% 감소함. 응급청구 총소요시간이 활동 전에 비해 ’07년 대비 77% 감소하고 타 병동 차용 총 소요시간이 61% 감소함. 전년 동기간 대비 수익이 4% 증가하였으며 또한 54병동과 보험 심사팀에서 직원들의 직무만족도가 향상되었다.

초음파 유도하 맘모톰 생검을 이용한 병변의 완전제거 : 6개월 추적 초음파 검사를 통해 알아본 유용성

김혜성,한부경,최연현,김지영,고영혜,양정현,남석진,김정한 대한초음파의학회 2004 ULTRASONOGRAPHY Vol.23 No.1

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

Lipopolysaccharide, Dexamethasone, 및 N-Nitro-L-Arginine Methyl Ester가 흰쥐 간 조직의 프리라디칼 발생과 제거에 미치는 영향

한기정,김석배,김양균,윤혜영,백광진,이희성,권년수 중앙대학교 의과대학 의과학연구소 2003 中央醫大誌 Vol.28 No.1

Lipopolysaccharide (LPS) stimulates various immune and inflammatory reactions to induces the generation of reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI). ROI and RNI are free radicals with very high reactivity, oxidize cellular constituents including proteins and lipid membranes, and thus play important roles in the pathogenesis of tissue damages in LPS-induced septic shock. The present study examined effects of dexamethasone (DexM), and N-nitro-L-arginine methyl ester (L-NAME) on the generation of ROI and RNI, and on the activities of enzymes removing ROI in the liver of rat model of septic shock. DexM has widely been used as an immunosuppressant. L-NAME has known to block synthesis of nitric oxide (NO), the main RNI, by inhibiting NO synthase (NOS). LPS (10 mg/kg body weight) markedly enhanced NO generation in serum and liver. The increased NO generation was completely blocked by pretreatment with DexM (10 mg/kg) and effectively inhibited by L-NAME (10 mg/kg). Induction of NOS protein expression by LPS was demonstrated by a Western analysis. The NOS expression was completely blocked by DexM pre-treatment, and markedly inhibited by L-NAME. However, the generation of superoxide radical, an important ROI, was not enhance in rat liver by LPS, rather it was decreased a little. Superoxide radical production was increased by L-NAME treatment or combined treatment of DexM and LPS. The level of lipid peroxidation, an index for free radical-induced cell damage, was increased by either LPS or DexM. The enhancement of lipid peroxidation by DexM was abolished by adding LPS. DexM markedly enhanced the activities of ROI removing enzymes, superoxide dismutase, glutathione peroxidase and catalase. However, rats were treated with LPS in addition to DexM, the elevated activities of superoxide dismutase, glutathione peroxidase and catalase were abolished. These results provide information on the generation and removal of ROI and RNI by LPS, DexM and L-NAME in rat liver, and on development of drugs to inhibit free radical-induced liver damage in sepsis.

기존 교육과정에서의 성과바탕 의학교육 이론 적용

홍영선,한재진,김정아,최희정,윤주천,정혜경,김한수 이화여자대학교 의과학연구소 2017 EMJ (Ewha medical journal) Vol.40 No.1

Objectives: This paper aims to describe an outcome-based curriculum development process at a medical school that has difficulty in advancement from the higher stage outcomes to the individual lesson outcomes, and to propose a way to implement it practically. Methods: We reviewed the objectives, strategies and previous products of the school’s taskforce activities and suggested the principle of bidirectional approaches of outcome based curriculum development. Results: The developing strategy identified such as firstly, the evaluation of present curriculum and then, the review of the outcomes developed previously with considering the nation-wide environmental change in medical education. Then, we selected one example course which was focused the resources of the school to, and finally the product of the example course was propagated to the other courses with central monitoring. Conclusion: Bidirectional model of ‘Top-down’ plus ‘Bottom-up’ approaches could be an efficient way to develop the outcome-based curriculum in a medical school, which has difficulties to advance the developing process due to various reasons including limited resources.

초등학교 자녀의 구강보건에 관한 학부모의 인식 및 행동

한수진,문혁수,정재연,김영경,이병진,김은경,정혜련 韓國學校保健學會 2001 韓國學校保健學會誌 Vol.14 No.1

The purpose of this study was to collect basic data for the development of oral health education program of parents and to encourage their actual interest and participation in school oral health program. The authors surveyed parents' awareness and behaviors about the oral health of their children. The subjects in this study were 193 parents of elementary school children in Seoul. The collected data were analyzed, the obtained results were as follows: 1. Thirty-five percent of the parents investigated paid a regular visit to a dental clinic. The must common tooth brushing time among them was after dinner, the second was after breakfast, and this was followed by before bedtime and before breakfast. 2. Ninety-four percent of the parents responded that prevention is necessary, 92.2% had a plan to visit a dental clinic to prevent dental caries, and 60.1% experienced receiving pit and fissure sealants. Ninety-seven percent responded that they did check their children's dental caries. 54.9% chocked their children's oral status after tooth brushing. The parents who visit a dental clinic on a regular basis were more likely to check their children's teeth after tooth brushing than those who don't(P<0.05). 3. Eighty eight percent of respondents wanted to keep the fluoride mouth rinse program. 4. It is recommended that an oral health education program be developed for parents to visit dental clinics on a regular basis, to educate as to the right tooth brushing time, and to check out their children's oral status after tooth blushing.

Lipopolysaccharide, Dexamethasone 및 23,24-Dihydrocucurbitacin D가 마우스 뇌조직의 프리라디칼 발생과 제거에 미치는 영향

한기정,강종권,윤혜영,백광진,이희성,권년수 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.4

부산시의 O_3 농도 변화 특성 및 시정에 관한 연구

한영옥,배혜진 부산교육대학교 교육대학원 2000 논문집 Vol.2 No.-

This study analysed O_3 concentration data and various data of meteorological factors to investigate the characteristics of O_3 concentration variation and determined how the high air pollutants concentration was generated under the meteorological condition. It also studied visibility variation and visibility impairment factors. The characteristics of O_3 concentration variation and the characteristics of O_3 episode day(≥60 ppb) were discussed on the base of the O_3 concentration data by air quality monitoring system in Pusan. Also the characteristics of visibility variation and visibility impairment factors were studied on the base of the visibility data and meteorological data of Pusan Meteorological Administration. According to the work, O_3 concentration was increased comparing to the previous year and coastal area was higher O_3 concentration than other area. O_3 episode day is annually increasing and the frequency of episode day is the most in summer. The high concentration of O_3 were occurred in narrow bounds and were not continued for long. Low mean wind speed were important meteorological parameter accompanying with the high episode days. Visibility was gradually decreased until 1990 and after then it was on the increase but poor visibility range became longer than good visibility range. So many people felt air pollution more seriously. Visibility impairment were influenced by TSP concentration, NO_2 concentration, temperature, wind speed and relative humidity. Especially increase of TSP concentration and relative humidity had high generation of low visibility.

한국인 주요우울장애 환자에서 혈중 ACTH, Cortisol 농도와 해밀턴 우울 평가 척도의 신체증상 항목과의 상관관계

여혜빈,김린,함병주,심세훈,권영준,정희연,정한용,한상우,이민수,이화영 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2

Objectives:Hypothalamic-Pituitary-Adrenocortical(HPA) system dysregulation plays an important role in the pathophysiology of major depressive disorder. Medically unexplained somatic symptoms comprised the predominant complaints of korean patients with major depressive disorder. It might be related to dysregulation of HPA system and somatic symptoms. The aim of this study was to investigate the association between Hamilton Depression Rating Scale severity and the Plasma Adrenocorticotropic Hormone(ACTH) & Serum Cortisol level in Korean patients with major depressive disorder. Methods:Our study design was prospective. A total 111 hospitalized patients with major depressive disorder (DSM-IV) at Anam Hospital, Korea University Medical Center between Jan 2009 and May 2011 were selected. Hamilton Depression Rating Scale was measured by psychiatrist. Plasma ACTH, Serum Cortisol levels were analyzed at the time of admission. Results:There are significant correlations(p<0.05) between Hamilton Depression Rating Scale of somatic component(HAM-D 11-15 item) and Plasma ACTH and Serum Cortisol level. However, other HAM-D sub items were not significantly correlated with Plasma ACTH and Serum Cortisol level except somatic component. Conclusion:Our Study results suggest that hyperactivity of HPA axis might be correlation with somatic symptoms in korean patients with major depressive disorder.