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      • 중환자에서 동맥혈 가스분석 횟수와 그로인한 실혈량에 대한 연구

        이석열,전철우,정영수,오희숙,마분란,이정미,정혜영,이만복,이길노 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

        Background : Arterial blood gas analysis is the most comon exam in intensive care unit. In this study, the frequency of blood gas analysis and the amount of blood loss after Blood Gas Analysis in Intensive Care Unit were observed. Methods : From November 1999 to February 2000, 115 patients admitted to intensive care unit at Soonchunhyang university Kumi hospital were studied prospectively for the frequency of blood gas analysis and the amount of blood loss after blood gas analysis in Intensive Care Unit. Results : The mean value of frequency of blood gas analysis was 6.41±6.49 and the mean value of amount of blood loss after blood gas analysis was 0.78ml. This was lower than that of other foreign reports. The patients with ventilator therapy above 24 hours showed higher frequency of blood gas analysis than that of not applied ventilator patients. Pulse oxymetry was applied to all patients and the frequency of blood gas analysis was decreased due to the use of strict pulse oxymetry. Conclusion : Doctors and nurses in intensive care unit keep in mind that adequate blood sampling is needed for the decrease of blood loss. Education and protocol for the decrease of blood loss after arterial blood gas analysis may be necessary.

      • KCI등재후보

        한국어 문법 교육에서 '표현항목' 설정에 대한 연구

        이미혜 국제한국어교육학회 2002 한국어 교육 Vol.13 No.2

        Mi-Hye Lee. 2002. A Study on the education of 'Grammar Marker-dependent Expressions' in current textbooks and establishing criteria instituting the expressions in Korean Grammar Education. Journal of Korean Language Education 13-2: 205∼225. This paper's purpose is to look at instituting 'Grammar Marker-dependent Expressions' which are included in current Korean grammar education. 'Grammar Marker-dependent Expressions' are defined as a group of words 'chunked' which include a grammar market. These expressions are difficult to sort into a precise grammatical category such as conjunctive endings, terminative endings or particles. In actual applications in Korean education classrooms many parts of grammar are presented as 'chunk' items, but up to now there has been no formal study conducted on 'Grammar Marker-dependent Expressions' as separate items. In studying whether present methods of how 'Grammar Market-dependent Expressions' are presented in classroom settings are beneficial and how to optimize the presentation of the items, this paper attempts the following: 1. Clearly define the concept of grammatical items and 'Grammar Marker-dependent Expressions' to make the study of the target clearer. This is especially important in that 'Grammar Marker-dependent Expressions' constitute a significant portion of the Korean education textbooks analyzed in the study. 2. Classify patterns of 'Grammar Marker-dependent Expressions' in existing materials for Korean grammar education. 3. Examine whether 'Grammar Marker-dependent Expressions' were combined with other points of grammar or introduced separately in current Korean textbooks and the possible reasons for doing so. 4. Present criteria to optimally standardize the institution of 'Grammar Marker-dependent Expressions' based on this paper's findings. (Ewha Womans Uninversity)

      • SCOPUSKCI등재

        New polymorphic microsatellite markers in the Korean mi-iuy croaker, $Miichthys$ $miiuy$, and their application to the genetic characterization of wild and farmed populations

        An, Hye-Suck,Kim, Eun-Mi,Lee, Jang-Wook,Kim, Dae-Jung,Kim, Yi-Cheong The Korean Society for Integrative Biology 2012 Animal cells and systems Vol.16 No.1

        Eighteen new polymorphic microsatellite markers were developed for the Korean mi-iuy croaker ($Miichthys$ $miiuy$, Perciformes, Sciaenidae), and allelic variability was compared between a wild population in Mokpo, Korea, and a hatchery population in Tongyeong, Korea. All loci were amplified readily and demonstrated allelic variability, with the number of alleles ranging from 5 to 37 in the wild population, and from 4 to 12 in the farmed population. The average observed and expected heterozygosities were estimated, respectively, to be 0.74 and 0.78 in the hatchery population samples, and 0.79 and 0.86 in the wild samples. These results indicate lower genetic variability in the hatchery population compared with the wild population, and significant genetic differentiation between the wild population and the hatchery samples ($F_{ST}$=0.058, P<0.001). These microsatellite loci may be valuable for future population genetic studies, monitoring changes in the genetic variation within stocks in a commercial breeding program, conservation genetics, and molecular assisted selective breeding of the mi-iuy croaker in the future.

      • 노인의 영적 간호요구

        최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

        This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

      • KCI등재

        일 도농복합지역 저소득층 노인의 건강문제 분석 : 보건소 방문간호사업 대상자 중심으로

        고일선,,이태화,이경자,이정렬,임미혜,천의영,주윤미,이계철 노인간호학회 2005 노인간호학회지 Vol.7 No.2

        Purpose: The purpose of this study was to analyze the health problems of low-income aged with chronic illness living in urban-rural composite area. Method: The sample consisted of 440 aged who were receiving home care services from a public health center. MDS-HC was applied to analyze the health problems of the aged. Data were collected through a face- to-face interview by six trained interviewers from June 28 to July 15, 2004. Result: Subjects had average number of 8 health problems in both urban and rural area. Lack of preventive health care measure, pain, and visual function were the most frequent health problem. The rural aged had more pain, bowel management problems, compared to the urban aged having more urinary incontinence and indwelling catheter. There were many health problems related to falls and pressure ulcers with middle-old aged in urban, and old-old aged in rural area. Conclusion: The results of this study showed strategies for care intervention of low-income elderly to put in practice. Therefore, tailored-service for each subject should be provided.

      • 다공성 하천구조물을 이용한 2차 처리수의 수질개선 효과

        이혜미,오종민,최이송 경희대학교 환경연구소 2002 環境硏究 論文集 Vol.11 No.-

        This study was performed to application of porous hydraulic structures(porous weir and porous river bed materials) to water purification in small and middle stream. This study was investigated the ability of water purification according to the variety of environmental conditions, periphytons and material of hydraulic structures. When the ordinary hydraulic structure was used as contact d a , the average removal efficiency of SS, BOD and COD were SS(48.4%), BOD(25.2%), COD(12.0%) respectively. Also when the porous hydraulic structure was used as contact media, the average removal efficiency of SS, BOD, COD and T-P were SS(83.0%), BOD(62.1%), COD(45.9%), T-P(32.3%) respectively. Judging from our results, porous concrete applied to the weir from took a great role of removal efficiencies of BOD, COD(low concentration range of organic materials) and T-P

      • KCI등재

        한국의 불문학 수용의 특성에 관한 비교 연구 : Une etude comparative avec d'autres litteratures occidentales

        이미혜 한국 프랑스어문교육학회 1998 프랑스어문교육 Vol.6 No.-

        A partir de 1895 ou Cho-Sun s'est ouvert officiellement s la civilisation occidentale, on a commence a recevoir la litterature occidentale. Le ministere de l'education a construit un appareil charge de publier des ouvrages historiques. Aussi des intellectuels progressistes ont-ils essaye d'instruire des lecteurs et de provoquer leur patriotisme par des romans adaptes. L'annexion de la Coree au Japon a diminue la tendance a recevoir activement la litterature occidentale. Dans les annees 10, il a paru seulement quelques romans feuilleton adaptes et simplifies. A partir de la Manifestation de 1919, le gouvernement colonial a cede sur la politique oppressive qu'il pratiquait, et a permis un minimum de liberte de la presse. Certains ont fonde des journaux et des revues dans lesquels ils ont commence a introduire des poetes symbolistes francais, des ecrivains russes comme Tolstoi et Tourgueniev. Sous la domination japonaise, la plupart des traducteurs et introducteurs de la litterature etrangere etaient ecrivains ou journalistes. Ils s'attachaient donc aux problemes du temps, ce qui explique la preference d'Yeats, de Tagore, poetes des pays colonises, et la preoccupation de la technique romanesque realiste. Apres la Liberation, on a retrouve la langue maternelle et la demande d'oeuvres traduites s'est agrandie. Dans les annees 50-60, des chefs-d'oeuvre classiques ont paru en edition collective bien que beaucoup d'entre eux soient retraduits des editions japonaises. Sous l'influence de la guerre froide, la reception de la litterature de langue anglaise etait en floraison, en revanche, celle de la litterature russe s'est diminuee remarquablement. D'autre part, on a commence 1'enseignement des litterature etrangereres dans des universites. Par degres des professeurs formaient la majorite des chercheurs, et jouaient un role important dans la reception. Des chercheurs universitaires s'essayaient a former des outils aptes a analyser la litterature coreenne en s'appuyant sur des theories litteraires occidentales comme la critique sociologique allemande et le structuralisme francais. Aujourd 'hui, de 1'expansion de 1'enseignement universitaire naissent bien des chercheurs qui effectuent des etudes plus approfondies et traduisent des oeuvres plus variees qu'auparavant. Mais masque's du developpement apparent, il se trouve des problemes a resoudre : la traduction inclinee exclusivement sur des oeuvres comtemporaines, surtout a des best-sellers, des etudes meprisant des lecteurs et meprisees par eux.

      • 스포츠관광상품개발에 관한 연구

        이미혜 경기대학교 2005 論文集 Vol.49 No.-

        The purpose of this study is to propose the Development of Tourism Product Sport for differentiating selling tourism product. In this research, the theories and case study of sport tourism product and new sport tourism product are reviewed. Thereafter Findings of new sport tourism product plan is four: experience-orientated, sport event-orientated , sport theme-orientated and region-orientated. At the conclusion, one of the most important thing in the development of the new sport tourism product. keeps up with the needs, preference and behavior changes of sport tourist.

      • KCI등재후보

        시험관내 심내막염 모델에서 Methicillin 내성 포도구균에 대한 Vancomycin, Arbekacin, Gentamicin 단독 혹은 병합효과

        이동건,전혜선,임동석,최수미,최정현,유진홍,신완식,강문원 대한감염학회 2003 감염과 화학요법 Vol.35 No.3

        목적 : Methicillin 내성 포도구균(methicillin resistant Staphylococcus aureus, MRSA)은 병원감염의 중요한 원인균으로 vancomycin이 선택약제이다. 그러나 심내막염 등의 중증감염에서는 vancomycin의 치료실패와 함께 최근 내성균도 증가하고 있어 vancomycin을 대체할 수 있는 항균제와 보다 효과적인 항균요법의 개발이 필요하다. 본 연구에서는 사람의 환경과 유사한 시험관내 감염 모델을 적용하여 MRSA 치료를 위한 vancomycin, arbekacin, gentamicin의 단독 및 병합효과를 비교하였다. 방법 : 임상에서 분리된 MRSA 2균주(GRI 53, gentamicin 내성 : GS171, gentamicin 감수성)로 fibrin clot을 제작하여 시험관내 심내막염 모델을 만들어 vancomycin, arbekacin, gentamicin을 단독 혹은 병합주입하였다. 반감기와 최고 및 최저농도는 사람의 약동학을 기준으로 하였다. Vancomycin은 6, 12, 24시간마다 주입하거나 24시간 연속주입하였고 arbekacin은 12, 24시간마다, gentamicin은 8, 24시간마다 주입하였다. 병합주입의 경우 vancomycin은 12시간마다, gentamicin, arbekacin은 24시간마다 투여하였다. 각 투여군의 살균효과는 0, 8, 24, 32, 48, 72시간째의 fibrin clot내 집락수로 측정하였다. 결과 : GRI153에 gentamicin을 주입한 군 이외의 모든 실험군에서 대조군에 비해 의미있게 fibrin clot내 집락수가 감소하였다(P<0.001). Vancomycin과 arbekacin 단독주입군내서 8시간째의 집락수는 GRI153보다 GS171에서 의미있게 낮았고(P=0.02), GS171에 arbekacin 12시간마다 투여한 군의 집락수가 가장 낮았다(P=0.01). 72시간째 집락수는 균주의 종류나 vancomycin 혹은 arbekacin의 투여간격에 따른 차이가 없었다. GRI153에서 vancomycin과 arbekacin의 병합주입군은 24시간까지 상가작용이 있었으나 vancomycin과 gentamicin 병합주입에서는 무관작용이었고 GS171에서도 72시간 동안 무관작용을 보였다. 또한 전 실험기간 동안 내성균은 발현되지 않았다. 결론 : 시험관내 심내막염 모델에서 MRSA에 대한 arbekacin의 항균력은 vancomycin과 유사하여 단독주입이 가능함을 시사한다. Gentamicin 내성균주의 경우 두가지 항균제의 병합주입으로 24시간까지 상가작용을 보이고 있으나 임상에 적용하기 위해서는 추가연구가 필요할 것으로 생각된다. Background : Glycopeptide has been used for the one-and-only treatment of choice in methicillin resistant Staphylococcus aureus (MRSA) infection, but its exclusive use for the MRSA infection has led to the increased risk of glycopeptide-resistance. To find an alternative (s), we employed an in vitro infective endocarditis model (IVIEM) to compare the efficacy of vancomycin (VCM). arbekacin (ABK), and gentamicin (GM) alone or in combination. Methods : Using two strains of clinically isolated MRSA, one GM susceptible (GS171) and the other GM resistant (GR153), fibrin clots were prepared and suspended in IVIEM. Antibiotics were added as a bolus to simulate human pharmacokinetics of regimens, including q 6 h, q 12 h, q 24 h, or continuous infusion with VCM, q 12h or q 24 h with ABK, and q 8 h or q 24 h with GM. In cases of combination, regimens were VCM q 12 h plus ABK q 24 h, and VCM q 12 h plus GM q 24 h. Fibrin clots were removed from each model at 0, 8, 24, 32, 48. and 72 h, and the bacterial densities (in CFU/g) were determined. Results : At 8 hour, the colony counts of GS171 were lower than those of GR153 (P=0.02), and the lowest with the ABK q12h against GS171 (P=0.01). At 72 hour, monotherapy with ABK or VCM produced same degree of bacterial reductions in IVIEM, regardless of dosing frequency or GM-resistance. In the case of GM-resistance, combination of VCM and ABK did show additive effect until 24 hours, although VCM and GM showed no indifference during all the experiments. Development of resistance during experiment was not observed with any regimens. Conclusions : Our data suggest that ABK monotherapy could be used as an alternative to VCM even in the treatment of GM-resistant staphylococcal endocarditis. Further studies will clinical trials are warranted to evaluate the additive effect of VCM and ABK.

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