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Fate of Acute Heart Failure Patients With Mid-Range Ejection Fraction
Gwag, Hye Bin,Lee, Ga Yeon,Choi, Jin-Oh,Lee, Hae-Young,Kim, Jae-Joong,Hwang, Kyung-Kuk,Chae, Shung Chull,Baek, Sang Hong,Kang, Seok-Min,Choi, Dong-Ju,Yoo, Byung-Su,Kim, Kye Hun,Park, Hyun-Young,Cho, M The Japanese Circulation Society 2018 CIRCULATION JOURNAL Vol.82 No.8
<P>Conclusions: One-third of HFmrEF patients showed improved LVEF; moreover, the survival rate in the improved group was higher than the other groups. Renin-angiotensin system blockers and aldosterone antagonists could improve the survival of HFmrEF patients.</P>
곽혜빈 ( Hye Bin Gwag ),정기선 ( Ki Sun Jung ),이지현 ( Ji Hyeon Lee ),김도희 ( Do Hee Kim ),임아영 ( A Young Lim ),김은경 ( Eun Kyoung Kim ) 대한내과학회 2015 대한내과학회지 Vol.89 No.3
Tuberculous-infected aortic aneurysms are rare, but delayed diagnosis can lead to serious complications, including sudden aortic rupture. Here, we report a case of a tuberculous infected aneurysm in the thoracic aorta that was mistaken for lymphadenopathy. In this case, we could differentiate the lesion with the aid of contrast-enhanced computed tomography and positron emission tomography (PET). This case demonstrates the diagnostic value of PET in aortic aneurysms. (Korean J Med 2015;89:323-326)
( Do Hee Kim ),( A Young Lim ),( Hye Bin Gwag ),( Ji Hyeon Lee ),( Ki Sun Jung ),( Keol Lee ),( Woo Seong Huh ),( Dae Joong Kim ),( Yoon Goo Kim ),( Ha Young Oh ),( Ki Hyun Kim ),( Gee Young Kwon ),( 대한신장학회 2014 Kidney Research and Clinical Practice Vol.33 No.2
Fanconi syndrome (FS) is a rare condition that is characterized by defects in theproximal tubular function. A 48-year-old woman was admitted for evaluation ofproteinuria. The patient showed normal anion gap acidosis, normoglycemic glycosuria,hypophosphatemia, and hypouricemia. Thus, her condition was compatiblewith FS. The M peak was found behind the beta globulin region in urine proteinelectrophoresis. Upon bone marrow examination, we found that 24% of cells wereCD138þ plasma cells with kappa restriction. From a kidney biopsy, we foundcrystalline inclusions within proximal tubular epithelial cells. Thereafter, shewas diagnosed with FS accompanied by multiple myeloma. The patient receivedchemotherapy and autologous stem cell transplantation, and obtained very goodpartial hematologic response. However, proximal tubular dysfunction was persistentuntil 1 year after autologous stem cell transplantation. In short, we report acase of FS accompanied by multiple myeloma, demonstrating crystalline inclusionin proximal tubular cells on kidney biopsy.
( A Young Lim ),( Ji Hyeon Lee ),( Ki Sun Jung ),( Hye Bin Gwag ),( Do Hee Kim ),( Seok Jin Kim ),( Ga Yeon Lee ),( Jung Sun Kim ),( Hee Jin Kim ),( Soo Youn Lee ),( Jung Eun Lee ),( Eun Seok Jeon ),( 대한내과학회 2015 The Korean Journal of Internal Medicine Vol.30 No.4
Background/Aims: The gastrointestinal (GI) tract often becomes involved in patients with systemic amyloidosis. As few GI amyloidosis data have been reported,we describe the clinical features and outcomes of patients with pathologically proven GI amyloidosis. Methods: We identified 155 patients diagnosed with systemic amyloidosis between April 1995 and April 2013. Twenty-four patients (15.5%) were diagnosed with GI amyloidosis using associated symptoms, and the diagnoses were confirmed bydirect biopsy. Results: Among the 24 patients, 20 (83.3%) had amyloidosis light chain (AL), three (12.5%) had amyloid A, and one (4.2%) had transthyretin-related type amyloidosis. Their median age was 57 years (range, 37 to 72), and 10 patients were female (41.7%).The most common symptoms of GI amyloidosis were diarrhea (11 patients, 45.8%), followed by anorexia (nine patients, 37.5%), weight loss, and nausea and/ or vomiting (seven patients, 29.2%). The histologically confirmed GI tract site in AL amyloidosis was the stomach in 11 patients (55.0%), the colon in nine (45.0%), the rectum in seven (35.0%), and the small bowel in one (5.0%). Patients with GIinvolvement had a greater frequency of organ involvement (p = 0.014). Median overall survival (OS) in patients with GI involvement was shorter (7.95 months; range, 0.3 to 40.54) than in those without GI involvement (15.84 months; range, 0.0 to 114.53; p = 0.069) in a univariate analysis. A multivariate analysis of prognostic factors for AL amyloidosis revealed that GI involvement was not a significant predictorof OS (p = 0.447). Conclusions: The prognosis of patients with AL amyloidosis and GI involvement was poorer than those without GI involvement, and they presented with more organ involvement and more advanced disease than those without organ involvement.