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황규홍,김상모 慶尙大學校生産技術硏究所 1999 生産技術硏究所論文集 Vol.15 No.-
Castable refractories are widely used due to their easy application to most of high temperature works. Among these low cement mullite-bonded castables with high forming density becomes the focus of attention due to high hot strength and excellent wear resistance against molten metals and slags. In this study, the flowability and workability of mullite-bonded castables were estimated as a function of the size of fine matrix phases and their compositions. It was found that the use of medium size alumina as the matrix phase, was an effective means for substantial increase of flowability and workability of castables. And by decreasing the q-value of Anderssen, nonvibrating flowability could be increased to the level for self-flow castables.
김상모,신현택,황규홍 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-
Recently there has been an increased demand for monolithic refractories. Among these Monolithic refractories castable are in particularly widely used because of their easy application to almost any kind of works. In this study the densification and volume stability of high alumina castable refractories was estimated as a function of aggregate size and composition, the amount of matrix phases, and their compositions. It was found that the particle size distribution equation given by Anderassen could be used for predicting the flowability of a castable with good agreement. The addition of microsilica and/or ultrafine-alumina decreased q-vale of Andreassen equation and resulted in better flowability of castables. Andalusite was substituted instead of fine alumina powder in the matrix for better volume stability. Despite of it's good ability for the mullite formation in the matrix, some ultrafine alumina should be added for preventing overfiring and bloating at high temperature. So castables with microsilica and ultrafine-alumina addition to matrix showed good workability and good resistance to large expansion at high temperature.
김성렬,황재익,김명모 東亞大學校 建設技術硏究所 2005 硏究論文集 Vol.29 No.1
Iai(1989) suggested the similitude law for 1g shaking table tests using basic equations governing the soil-structure-fluid systems. However, the validity of this similitude law was not fully verified. In this research, shaking table tests for gravity type quay walls were performed to verify the similitude law for soil-structure interaction problems. The validity of the similitude law was analyzed by checking whether different sizes of models show the same physical behavior. The test results showed that the excess pore pressure and the dynamic thrust acting on quay walls were difficult to be simulated in model tests. However, it was found that the displacement of the wall can be properly predicted from model tests if the total force acting on the wall is simulated in models.
Bacillus sp. KCM-101에 의한 내열성 α-amylase의 생산 및 효소학적 성질
강상모,최유정,황윤영,이동희,권태종 건국대학교 산업기술연구원 2000 건국기술연구논문지 Vol.25 No.-
A strain isolated from soil was able to produce thermostable α-amylase. The strain (KC-101) was identification as Bacillus sp. Bacillus sp. KC-101 was treated NTG(N-methyl-nitro-nitrosoguanidine). The mutant KCM-101 increased α-amylase activity and decreased pretease activity. The condition for production, purification, and properties of α-amylase were investigated. α-Amylase production was maximized when was grown on soluble starch 2.0%, yeast extract 0.5%, K2HPO4 0.1% and MnCl2 0.02% for 24hrs at 37℃, and initial pH 7.0. The enzyme production was also increased by the addition of 0.01% Triton X-100. The enzyme was purified by ultrafiltration(MW 10,000), 80% ammonium sulfate precipitation, and Sephadex G-75 gel chromatography and it's yield 15.0%, The characteristics of purified α-amylase were as follow : MW 55,000, optimal pH and temperature were 7.0 and 95℃, respectively. The enzyme was activated by Ca++ and Mn++ ion but inhibited Co++, Cu++, Hg++, and Pb++ ion. The enzyme was stable at 95℃ and it's thermostability was greatly increased by the addition of Ca++. In kinetic studies, the Km value of α-amylase for soluble starch was 0.93mg/mL.
Sung Kwon Kim,Jangsup Moon,Jin Mo Cho,Kyung Hwan Kim,김세훈,김영일,김영준,Ho Sung Kim,도윤식,박재성,Ji Eun Park,서영범,Kyoung-Su Sung,송진호,Chan Woo Wee,Wan-Soo Yoon,윤홍인,Se-Hoon Lee,임도훈,임정호,장종희,한명훈,홍제범,Kihwan Hwang,박철기,이 대한뇌종양학회 2020 Brain Tumor Research and Treatment Vol.8 No.1
Background: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey for diverse queries faced in the treatment of brain tumors. As part I of the survey, the aim of this study is to evaluate national patterns of clinical practice about antiepileptic drug (AED) and steroid usage for management of brain tumors. Methods: A web-based survey was sent to all members of the KSNO by email. The survey included 9 questions of AED usage and 5 questions of steroid usage for brain tumor patients. All questions were developed by consensus of the Guideline Working Group. Results: The overall response rate was 12.8% (54/423). Regarding AED usage, the majority of respondents (95.2%) routinely prescribed prophylactic AEDs for patients with seizure at the peri/postoperative period. However, as many as 72.8% of respondents prescribed AED routinely for seizure-naive patients, and others prescribed AED as the case may be. The duration of AED prophylaxis showed wide variance according to the epilepsy status and the location of tumor. Levetiracetam (82.9%) was the most preferred AED for epilepsy prophylaxis. Regarding steroid usage, 90.5% of respondents use steroids in perioperative period, including 34.2% of them as a routine manner. Presence of peritumoral edema (90.9%) was considered as the most important factor determining steroid usage followed by degree of clinical symptoms (60.6%). More than half of respondents (51.2%) replied to discontinue the steroids within a week after surgery if there are no specific medical conditions, while 7.3% preferred slow tapering up to a month after surgery. Conclusion: The survey demonstrated the prevailing practice patterns on AED and steroid usage in neuro-oncologic field among members of the KSNO. This information provides a point of reference for establishing a practical guideline in the management of brain tumor patients.
Sung Kwon Kim,Ji Eun Park,Kyung Hwan Kim,Jin Mo Cho,문장섭,Wan-Soo Yoon,김세훈,김영일,김영준,Ho Sung Kim,도윤식,박재성,윤홍인,서영범,Kyoung-Su Sung,송진호,Chan Woo Wee,Se-Hoon Lee,임도훈,임정호,장종희,한명훈,홍제범,Kihwan Hwang,Chul-Kee Park 대한뇌종양학회 2020 Brain Tumor Research and Treatment Vol.8 No.1
Background: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted the nationwide questionnaire survey for diverse queries facing to treat patients with brain tumor. As part III of the survey, the aim of this study is to evaluate the national patterns of clinical practice for patients with brain metastasis and primary central nervous system lymphoma (PCNSL). Methods: A web-based survey was sent to all members of the KSNO by email. The survey included 7 questions of brain metastasis and 5 questions of PCNSL, focused on the management strategies in specific situations. All questions were developed by consensus of the Guideline Working Group. Results: In the survey about brain metastasis, respondents preferred surgical resection with adjuvant treatment for patients with a surgically accessible single brain metastatic lesion less than 3 cm in size without extracranial systemic lesions. However, most respondents considered radiosurgery for surgically inaccessible lesions. As the preferred treatment of multiple brain metastases according to the number of brain lesions, respondents tended to choose radiotherapy with increasing number of lesions Radiosurgery was mostly chosen for the brain metastases of less than or equal to 4. In the survey about PCNSL, a half of respondents choose high-dose methotrexate-based polychemotherapy as the first-line induction therapy for PCNSL. The consolidation and salvage therapy showed a little variation among respondents. For PCNSL patients with cerebrospinal fluid dissemination, intrathecal chemotherapy was most preferred. Conclusion: The survey demonstrates the prevailing clinical practice patterns for patients with brain metastasis and PCNSL among members of the KSNO. This information provides a point of reference for establishing a practical guideline in the management of brain metastasis and PCNSL.