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RISS 인기검색어
- 검색키워드
- 저자 : ( Hanyeong Wang ) (검색결과 5 건)
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Spontaneous regression of acquired melanocytic nevus without peripheral halo
( So Young Jung ),( Hanyeong Wang ),( Wonkyung Lee ),( June Eun Seol ),( Hyojin Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Halo nevus is a pigmented nevus surrounded by depigmented patch clinically and it can be seen aroundacquired or congenital melanocytic nevus, blue nevus, Spitz nevus, dysplastic nevus or melanoma. Rarely halo nevus without halo can occur. In that case, nevus shows identical histologic features to those seen in halo nevus but without presenting a halo clinically. A 41 year-old male presented with hyperpigmented macule on the back. The lesion occurred and had been darkened since 6 months before. On physical examination, 1.5 X 1.5 cm sized hyperpigmented plaque was seen on the back, however, there was no depigmentation around the plaqueor other parts of body. Histopathologic findings of the lesion revealed dense lichenoid infiltration with nevoid cell nests in upper dermis, which was compatible with halo nevus. Halo nevus is related with spontaneous regression of the nevus that we decided to observe the lesion withoutany treatment. One year later, it disappeared without depigmentation. Herein, we report a case of histologically proven halo nevus without halo showing spontaneous regression.
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Lepromatous leprosy with type II reaction misunderstood as Tsutsugamushi disease
( So Young Jung ),( Hanyeong Wang ),( Jun Young Kim ),( Wonkyung Lee ),( Jung Eun Seo ),( Hyojin Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Leprosy is chronic granulomatous infection caused by Mycobacterium leprae and affects primarily skin and nerve. The incidence and newly diagnosed case has decreased over the years, so it can be misdiagnosed as other granulomatous diseases such as sarcoidosis, cutaneous tuberculosis or other infectious diseases at first inspection. A 62 year-old female had multiple erythematous indurated plaques on whole body with fever that developed 3 weeks ago. Under clinical impression of tsutsugamushi disease, she took doxycycline for 3 days, however, her symptoms was not improved. For further evaluation, she was hospitalized and on physical examination, hair loss of both eyebrows were seen and stocking-glove pattern of sensory impairment, anhidrosis of palms and soles were checked. Histopathologic examination showed granulomatous inflammation with foamy histiocytes in the dermis and marked upper dermal edema. And numerous bacilli were seen on Wade-Fite stain. Lepromatous leprosy with type II reaction was diagnosed. After taking methylprednisolone, clarithromycin, rifampicin, ofloxacin, minocin and NSAID for 5 days, the reactional symptoms improved dramatically. After then she is treated with rifampicin, ofloxacin and minocin. Herein, we report a case of lepromatous leprosy with type II reaction which was misunderstood as tsutsugamushi disease due to the low incidence of this disease recently.
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( So Young Jung ),( Hanyeong Wang ),( Wonkyung Lee ),( Jung Eun Seol ),( Hyojin Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Recently, TNF-α inhibitors has been widely used in the treatment of various inflammatory disease such as psoriasis. However, new-onset or worsening of psoriasiform eruption can be occurred paradoxically during TNF-α inhibitor treatment, that is called paradoxical effect. Here, we report a case of palmoplantar pustulosis occurred in the patient after injection of adalimumab and following golimumab for the treatment of ankylosing spondylitis. A 52-year-old man presented with asymptomatic erythematous scaly patches with pustules on his palms and soles, which developed 3 months ago. He had ankylosing spondylitis that had been treated with adalimumab for 3 years. Histopathologic examination showed psoriasiform hyperplasia with intraepidermal neutrophilic aggregation. As adalimumab is thought to be the cause of this eruption, the rheumatologist decided to discontinue adalimumab injection and his skin lesions were improved after 4 weeks treatment with cyclosporine, topical calcipotriol and corticosteroid combination cream. However, as he suffered from a relapse of back pain, golimumab as a substitute for adalimumab was initiated to control ankylosing spondylitis. After 4th injection, his palmoplantar psoriasiform eruption recurred. Considering the situation that TNF antagonist cannot be stopped, we decided to control the skin lesion with topical agent and occasional use of systemic cyclosporine and corticosteroid.
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Cutaneous metastasis of tonsillar squamous cell carcinoma occurred on the thigh
( Sung Hwan Hwang ),( So Young Jung ),( Hanyeong Wang ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Skin metastasis from internal organ malignancy is very rare, but can occur in any body part and at any time during the course of primary carcinogenesis. Herein, we report a rare case of cutaneous metastasis of tonsillar squamous cell carcinoma occurred on the thigh. A 58-year-old Korean man presented with a 3-week history of painful, erythematous nodule on his left thigh. He was diagnosed with tonsillar squamous cell carcinoma two years prior, and had been undergoing chemotherapy. Histologic examination showed nodular aggregates of pleomorphic and hyperchromatic keratinocytes throughout the dermis, with no involvement of the epidermis. They were positive for CK5/6 and p63. And polymerase chain reaction revealed the presence of human papillomavirus type 16 DNA. The nodule on the thigh was diagnosed as metastatic squamous cell carcinoma of tonsillar origin. Head and neck cancer metastasis most commonly involve the lymph nodes, lung, and bone around the head and neck. However, distant metastasis to the skin is very rare. This case emphasizes the fact that new skin lesions in the distal part of primary cancer sites, including tonsillar malignancy, should be evaluated to rule out metastatic carcinoma.
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Combined treatment of atrophic acne scars with polydioxanone (PDO) thread
( Hwang Sung Hwan ),( Jung So Young ),( Wang Hanyeong ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Atrophic acne scar can be found in up to 90% of patients with acne and causes various medical and cosmetic problems that cause significant impact on quality of life. Many options are available for the treatment of acne scars, which include various laser treatments, dermabrasion, chemical peeling, subcision, punch techniques and others. Alone these treatments are less effective and often prone to side effects. Recently hyaluronic acid fillers have been used, but the results have been various depending on the lesion conditions or on the technique used with possible side effects including foreign body reaction and skin necrosis. We used a randomized split-face trial in four 20-year-old male patients. Each of the participants received a subcision, followed by an insertion of a spiral type PDO thread with 23-gauge needles, then an erbium fractional laser treatment on one side. The other side received the same treatment excluding the thread insertion. The therapeutic effects were evaluated at baseline, week 4, and week 12. The side treated with POD thread insertion showed excellent results with good patient satisfaction. And no serious adverse effects were observed. We suggest that combining spring-shaped polydioxanone thread insertion with other therapies can be an effective treatment candidate for atrophic acne scars.
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