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김한샘(Kim, Han-saem) 우리말글학회 2015 우리말 글 Vol.65 No.-
초등학교 교과서 어휘 분석 말뭉치를 대상으로 고유어 명사 파생 접두사의 생산성을 측정해 보았다. Baayen(1989)의 방법론을 한국어에 적용하기 위해 기존 공식을 검토하여 생산성 측정식을 ‘P = (n1+U+1)?T/N’로 제안하였다. n1은 단발어의 수, U는 미등재어의 수, T는 해당 접사 형성 파생어 종수, N은 빈도가 평균 빈도 이하인 해당 접사 형성 파생어 빈도의 총합을 의미한다. 측정 결과 ‘수- > 한- > 참- > 통- > 암- > 실-, 헛-> 맞-, 덧- > 쇠- > 맨- > 개-, 햇- > 알-, 줄-, 쪽-, 풋-, 날- > 돌- >잔- > 들-, 막-, 찰- > 먹- > 맏- > 늦-, 민-, 외- > 군- , 말-, 웃- >홀- > 메- > 겹- > 떡-’의 순으로 생산성이 측정되었다. 접사의 생산성에 대한 논의는 어종, 세부 범주의 측면에서 확대되어야 하며 그간의 이론적인 연구를 어떻게 어휘 교육에 적용할 것인가로 발전해 나가야 할 것이다. Elementary school textbooks looked vocabulary corpus in this study to measure the productivity of native language noun derived prefix. Baayen(1989) review the existing formula to apply the methodology was proposed in Korean productivity measuring expression as "P = (n1 + U + 1) .T / N". n1 is the number of Sudan I, U is the number of tail lamp Measure, T is the total sum of the macro means forming species derivatives, N is the frequency of the average frequency of less than or equal to the frequency of the macro forming derivatives. Measurement "Su- > Han- > Cham- > Tong- > Am- > Si-, Heot- > Mat-, Deot- > Soe- > Maen- > Gae-, Haet- > Al-, Jul-, Jjok-, Put-, Nal- > Dol- > Jan- > Deuls -, Mak-, Chal- > Meok- > Mat- > Neut-, Min-, Oe- > Gun-, Mal-, Ut- > Hol- > Me- > Gyeop- > Ddeok" was measured in the order. Discussion on the productivity of the macro is to be expanded in terms of species, will get developed into detailed categories and how to apply the theoretical study of vocabulary teaching meantime.
[P417] A case of rheumatoid neutrophilic dermatosis mimicking herpes simplex infection
( Han-saem Kim ),( Junghwa Yang ),( Yun Ho Lee ),( Jung Yup Kim ),( Sunmin Yim ),( Jae Yun Lim ),( Ju-yeon Choi ),( Joon Hong Min ),( Young Jun Choi ),( Jae-hui Nam ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder. Various cutaneous manifestations are associated with RA, including rheumatoid nodule, vasculitis, palisading granulomatous dermatitis, and neutrophilic disorders. Rheumatoid neutrophilic dermatitis (RND) occurs in patients with active and severe RA, and vesicular-type RND is rarely reported, which predominantly involves the lower extremities. A 66-year-old female presented a 6-year history of RA. She had successfully treated with the combination of systemic prednisolone and methotrexate. At the beginning of 2015, erythematous vesicles with crust and erosion suddenly began to spread symmetrically on the both thighs. The lesion was accompanied with intermittent pain. The patient was initially treated with oral acyclovir and a mid-potent topical steroid, based on the diagnosis of herpes simplex. The lesions, however, were recurrent every month despite taking medications. A year later, a skin biopsy was performed. The histological examination showed intracorneal pustules and dense dermal inflammatory infiltrates, consisting mainly of adundant neutrophils. There were endothelial swelling and luekocytoclasis, but no vasculitis. The patient was then started on leflunomide for the control of RA with satisfactory preliminary skin response. The based on the clinical and histological features, RND was diagnosed.
Construction of Yonsei 20th Century Corpus
( Han Saem Kim ) 연세대학교 언어정보연구원 2016 언어사실과 관점 Vol.37 No.-
연세20세기 말뭉치는 20세기 이후 현대국어를 기술하는 사전을 편찬할 목적으로 접근 가능한 전자 텍스트를 최대한 수집하는 것을 목표로 하였다. “연세현대한국어대사전”은 기술의 대상이 되는 현대국어 어휘의 시간적 범위를 20세기 전반으로 확대한 것이다. 20세기 초의 국어와 현재의 국어가 다르다는 것을 전제로 할 때 사전에서 현대국어를 기술한다는 것은 20 세기 이후의 국어 어휘의 통시적 변화를 기술하는 것과 같은 맥락이다. 20세기 100 년을 10년 단위로 나누고 매체와 텍스트의 성격을 중심으로 신문, 잡지, 문학적 텍스트, 정보적 텍스트, 교과서의 대분류를 설정하여 지금까지 약 1 억 4천 어절의 말뭉치를 구축하였다. 연세 20 세기말뭉치는 현재 상태에 고정되지 않고 구축 중인 말뭉치이며 20 세기 초기의 신문, 정보적 텍스트 등 비어 있는 부분을 위주로 지속적으로 확장해 나가는 중이다. 말뭉치의 양이나 균형성의 측면에서 아직 미완성이고 검색 시스템의 기능이 단순하고 제약적이지만 말뭉치온라인 용례 검색기에서 옛한글 입출력을 구현한 것이 처음이므로 연세 20 세기말뭉치가 20세기 국어 연구에 기여하는 바가 있을 것이다. 어휘의 통시적 변화 및 경쟁 관계, 외래어의 의미와 표기 분화, 품사 범주의 문법화 등 다양한 관점에서 연세 20 세기말뭉치를 국어 연구에 활용할 가능성에 대해 예를 보였다.
P073 Rosacea and its association with enteral microbiome and systemic diseases
( Han-saem Kim ),( Jung Yup Kim ),( Sunmin Yim ),( Jae Yun Lim ),( Ju-yeon Choi ),( Jung-in Kim ),( Jung Min ),( Ho Joo Jung ),( Joon Hong Min ),( Young Jun Choi ),( Jae Hui Nam ),( Ga-young Lee ),( W 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Rosacea is a common chronic inflammatory skin disease. Recently, it is revealed that systemic diseases are associated with rosacea. Objectives: To investigate the relationship between gut microbiome, associated diseases and rosacea. Methods: A cross-sectional analysis was performed among healthy female subjects. Study data were obtained from 282 subjects who participated in a health check-up program. Rosacea was assessed by a questionnaire. Other medical illnesses were evaluated by thorough medical examination and history taking. Stool microbiota was analysed by QIIME (Quantitative Insights Into Microbial Ecology) software. Results: The study included 12 patients with rosacea and 270 subjects without rosacea (control group). After adjusting for age, body mass index (BMI) was significantly higher in rosacea patients as compared with the control group (odds ratio 1.20, 95% confidence interval 1.02-1.42). Seven metagenomic genera were correlated with rosacea: Peptococcaceae family unknown genus, Methanobrevibacter genus, Acidaminococcus genus, Megasphaera genus, Lactococcus genus, Eggerthella genus, Lactobacillales order unknown family unknown genus (p<0.05). Conclusion: This study shows that rosacea is associated with BMI and specific gut microbiota.
Kim, Han-Saem,Chung, Choong-Ki,Kim, Jeong-Jun Geological Society of London 2018 Quarterly journal of engineering geology and hydro Vol.51 No.1
<P>Borehole data are more commonly used than other geotechnical methods for determining the 3D geospatial information of a given site. However, the inadequate acquisition of continuous geotechnical information over an entire site limits the usefulness of this technique. In contrast, 2D continuous geophysical tomography over a large area reveals geophysical characteristics that can be transformed into geotechnical information. It is therefore possible to obtain more reliable stratal information by combining borehole datasets and geophysical measurements using geostatistical methods. In this study, a 3D geostatistical integration method incorporating site-specific geotechnical variability was proposed to construct a 3D geospatial database for developing geological unit boundaries for engineering projects. First, borehole datasets, reviewed by a geologist, were modified to fit a geostatistical trend of geological strata using a cross-validation-based outlier detection method. Then, site-specific geological layer criteria were determined based on proper statistical comparisons to convert geophysical values into boundary criteria for each geological layer. Finally, 3D geospatial information incorporating site-specific geomaterial characteristics was determined using indicator kriging. The proposed framework was established as functional modules in a geographic information system (GIS) platform and applied to three testbeds in Korea, incorporating a variety of site conditions such as spatial variability of coastal and mountainous areas, to validate its applicability depending on various geophysical characteristics. Application of the proposed framework indicates increases in estimation accuracy of 3D subsurfaces using geophysical and borehole information. However, the geostatistical integration of the two datasets has limited application in areas of geological complexity, such as areas with faults or anisotropic geological strata.</P>
A New α-Amylase from Reticulitermes speratus KMT1
Han Saem Park,Young Seok Ham,Hee Hoon Ahn,Keum Shin,Yeong Suk Kim,Tae Jong Kim 한국목재공학회 2014 목재공학 Vol.42 No.2
Termites are wood pests that cause vast economic damage every year. They digest both cellulose and starch, but the enzymes for starch digestion have not been well characterized. We obtained complete amino acid sequence information on the KME1 α-amylase from Reticulitermes speratus KMT1 through analysis of total mRNA sequences. The KME1 enzyme has two α-amylase domains and is 68% identical to the α-amylase from Blattellager manica, its closest rela-tivein the GenBank database. Some unique features of its conserved region and its distant evolutionary relationship to other insect α-amylases suggest that KME1 is a new type of α-amylase.