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Han Thi Vo,Tien Duc Dao,Tuyen Van Duong,Tan Thanh Nguyen,Binh Nhu Do,Tinh Xuan Do,Khue Minh Pham,Vinh Hai Vu,Linh Van Pham,Lien Thi Hong Nguyen,Lan Thi Huong Le,Hoang Cong Nguyen,Nga Hoang Dang,Trung 질병관리청 2024 Osong Public Health and Research Persptectives Vol.15 No.1
Objectives: The incidence of posttraumatic stress disorder (PTSD) has increased, particularly among individuals who have recovered from coronavirus disease 2019 (COVID-19) infection. Health literacy is considered a “social vaccine” that helps people respond effectively to the pandemic. We aimed to investigate the association between long COVID-19 and PTSD, and to examine the modifying role of health literacy in this association.Methods: A cross-sectional study was conducted at 18 hospitals and health centers in Vietnam from December 2021 to October 2022. We recruited 4,463 individuals who had recovered from COVID-19 infection for at least 4 weeks. Participants provided information about their sociodemographics, clinical parameters, health-related behaviors, health literacy (using the 12-item short-form health literacy scale), long COVID-19 symptoms and PTSD (Impact Event Scale-Revised score of 33 or higher). Logistic regression models were used to examine associations and interactions.Results: Out of the study sample, 55.9% had long COVID-19 symptoms, and 49.6% had PTSD. Individuals with long COVID-19 symptoms had a higher likelihood of PTSD (odds ratio [OR], 1.68; 95% confidence interval [CI], 1.63–2.12; p<0.001). Higher health literacy was associated with a lower likelihood of PTSD (OR, 0.98; 95% CI, 0.97–0.99; p=0.001). Compared to those with long COVID-19 symptoms and the lowest health literacy score, those with long COVID-19 symptoms and a 1-point health literacy increment had a 3% lower likelihood of PTSD (OR, 0.97; 95% CI, 0.96–0.99; p=0.001).Conclusion: Health literacy was found to be a protective factor against PTSD and modified the negative impact of long COVID-19 symptoms on PTSD.
Truong Xuan NGUYEN,Khai Quang LUU,Thien Thuan Hoang NGUYEN,An Van HA,Han Bao Huynh NGUYEN,Anh Nhu Thi BUI 한국유통과학회 2018 KODISA ICBE (International Conference on Business Vol.2018 No.-
This study to explore and examines the factors affecting 4.0 industrial adoption in enterprises in Ho Chi Minh City. The research model based on the two main research theories is the Technology Adaptation Model (Davis, 1989) and the Theory of Planned Behavior (Ajzen, 1991), and previous literature on technology 4.0 to build conceptual models which appropriate to the research content. Both qualitative and quantitative research methods are applied in the study. Qualitative research is conducted first in the form of in-depth interviews to adjust the conceptual model. Quantitative research was then used to verify the conceptual model. Samples taken by the non-probability method and convenience sampling technical through the official questionnaire for 380 small and medium enterprises have been applying elements of industry 4.0. The results show that in addition to the effect of Intent to Use on Use decision, in the group of independent variables affecting Perceived Usefulness of the business, turning Perceived Saving Cost has the strongest impact, and in the group of independent variables which influence Intent to Use, the Business Resource variable has the strongest impact.
( Tuan Hiep Tran ),( Tuan Duc Nguyen ),( Han Van Nguyen ),( Hanh Thuy Nguyen ),( Jong Oh Kim ),( Chul Soon Yong ),( Chien Ngoc Nguyen ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-
Polyro.t-lactic-co-glycolic acid) (PLGA) nanoparticles with negative surface charge were reversed to positive by cationic surfactant-DDAB before being coated with an anionic polymer, hyaluronic acid, to improve their site-specific intracellular delivery against CD44 receptor overexpressing cancer cells. Incorporating artesunate (ART)-a promising anticancer drug into PLGA/HA nanoparticles, is expected not only to overcome its poor aqueous solubility and stability but also enhance the activities. The obtained particles were characterized by dynamic light scattering, zeta potential measurements, and transmission electron microscopy (TEM). Cancer cell internalization of the NPs was evaluated by flow cytometry and cytotoxicity of the NPs was tested by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay. PLGA/HA nanoparticles showed greater extent of cellular uptake to SCC-7 and MCF-7 cells, indicating their affinity with CD44 receptor-mediated endocytosis. Almost 60 % of ART was released into the outer media after 48 h. In vitro fluorescence sorting demonstrated that PLGA/HA had highly efficient targeting and accumulation into CD44 receptor overexpression cells. The significant reduction in cell viability as well as greater induction of apoptosis suggested a potential in anticancer therapy of ART loaded PLGA/HA.
Van Phap Nguyen,조진성,이지훈,김민하,최영임,박응준,김원찬,황성빈,Kyung-Hwan Han,고재흥 한국식물학회 2017 Journal of Plant Biology Vol.60 No.2
Unlike xylem, which is primarily composed of dead cells in vascular bundles, phloem has living cells. It transports organic nutrients and long-distance communication signals to all parts of plants. In this report, we describe a promoter from Populus trichocarpa that drives strong gene expression in a phloem tissue-specific manner. First, we identified five candidate genes with strong expression in the developing phloem (DP) tissue from whole-transcriptome gene chip analyses of different tissue types of poplar. The putative promoter sequences of them were isolated and tested for their promoter activity in transgenic Arabidopsis plants. Among them, a promoter of the Potri.001G340200.1 gene (called the PtrDP3 promoter) was identified that has the strongest activity in phloem tissue. PtrDP3 promoter activity was found exclusively in phloem cells of the stem and root tissues of transgenic Arabidopsis plants, which was reproduced in the transgenic poplar plants. The phloemspecific activity of the PtrDP3 promoter was detected as early as in three-day-old seedlings and was not affected by abiotic stresses or exogenously applied plant hormones in transgenic Arabidopsis plants. Promoter deletion analysis identified a 100-bp regulatory region of the PtrDP3 promoter, which is necessary to drive phloem specific expression. This study provides evidence of a strong phloem-specific promoter that is suitable for phloem-specific biotechnological modifications in plants.
Nguyen Van Duc Long,이동영,Thi Hiep Han,박선용,황병봉,이문용 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.11
Many design variables and constraints, such as operating temperature and pressure of existing batch distillation or operating temperature of existing cooling and heating media, must be verified and satisfied during design and optimization when an existing batch distillation column is utilized for new mixture. The convergence of batch distillation simulation is sensitive with the initial values of these variables. Thus, a new systematic methodology was proposed to design and optimize separation of a new mixture using an existing batch column. The systematic methodology was based on an industrial case study of dichlorodifluoromethane (R-12) reclamation from a waste refrigerant mixture. Based on a comparison of the Pxy diagram with experimental data, “REFerence fluid PROPerties” was selected as the thermodynamic model. After design and optimization using shortcut and rigorous methodologies, the existing batch distillation unit was operated to validate the proposed methodology. The experimented performance match well with the simulated results. Under the optimized operating condition, complete purification of R-12 (purity=99.5%) was achieved experimentally after 28.3 h. The advantages and disadvantages of the proposed methodology were then discussed.